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Angiogénesis

Angiogénesis

Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.

Subcategorías de "Angiogénesis"

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Se han encontrado 2121 productos de "Angiogénesis"

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  • MNS

    CAS:
    MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
    Fórmula:C9H7NO4
    Pureza:98.53%
    Forma y color:Yellow Powder
    Peso molecular:193.16
  • 5-phenylthieno[2,3-d]pyrimidin-4-amine

    CAS:
    5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.
    Fórmula:C12H9N3S
    Pureza:97%
    Forma y color:Solid
    Peso molecular:227.29
  • Vandetanib

    CAS:
    Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.
    Fórmula:C22H24BrFN4O2
    Pureza:99.7% - >99.99%
    Forma y color:White Solid
    Peso molecular:475.35
  • Vandetanib trifluoroacetate

    CAS:
    Vandetanib trifluoroacetate: oral VEGFR2/KDR inhibitor, IC50=40nM, also blocks VEGFR3/FLT4 (110nM) and EGFR/HER1 (500nM).
    Fórmula:C24H25BrF4N4O4
    Forma y color:Solid
    Peso molecular:589.386
  • SPHINX31

    CAS:
    SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
    Fórmula:C27H24F3N5O2
    Pureza:99.3% - 99.87%
    Forma y color:Solid
    Peso molecular:507.51
  • ZM-447439

    CAS:
    ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.
    Fórmula:C29H31N5O4
    Pureza:99.11% - 99.59%
    Forma y color:Pale Yellow Solid
    Peso molecular:513.59
  • PD153035

    CAS:
    PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,
    Fórmula:C16H14BrN3O2
    Pureza:98.47% - 99.29%
    Forma y color:Solid
    Peso molecular:360.21
  • Momelotinib HCl

    CAS:
    Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.
    Fórmula:C23H24Cl2N6O2
    Forma y color:Solid
    Peso molecular:487.38
  • SU6656

    CAS:
    SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.
    Fórmula:C19H21N3O3S
    Pureza:98.21% - 98.73%
    Forma y color:Solid
    Peso molecular:371.45
  • AG490

    CAS:
    AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.
    Fórmula:C17H14N2O3
    Pureza:98.6% - 99.85%
    Forma y color:Yellow Solid
    Peso molecular:294.3
  • Olverembatinib dimesylate

    CAS:
    Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).
    Fórmula:C29H27F3N6O·2CH4O3S
    Pureza:97.66% - >99.99%
    Forma y color:Solid
    Peso molecular:724.77
  • Zoligratinib

    CAS:
    Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
    Fórmula:C20H16N6O
    Pureza:95.28% - 99.51%
    Forma y color:Solid
    Peso molecular:356.38
  • PD-161570

    CAS:
    PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.
    Fórmula:C26H35Cl2N7O
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:532.51
  • Crizotinib hydrochloride

    CAS:
    Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)
    Fórmula:C21H23Cl3FN5O
    Pureza:98.73% - 98.87%
    Forma y color:Solid
    Peso molecular:486.8
  • AC1NS4RE

    CAS:
    It is a tyrosine kinase inhibitor.
    Fórmula:C15H13ClN2O
    Pureza:99.53%
    Forma y color:Solid
    Peso molecular:272.73
  • Mubritinib

    CAS:
    Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
    Fórmula:C25H23F3N4O2
    Pureza:98.61% - 99.85%
    Forma y color:Solid
    Peso molecular:468.47
  • CYC-116

    CAS:
    CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active
    Fórmula:C18H20N6OS
    Pureza:97.36% - 97.59%
    Forma y color:Solid
    Peso molecular:368.46
  • lavendustin C

    CAS:
    lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
    Fórmula:C14H13NO5
    Pureza:98.06%
    Forma y color:Yellow To Tan Powder
    Peso molecular:275.26
  • BMS817378

    CAS:
    <p>BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).</p>
    Fórmula:C24H18ClF2N4O7P
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:578.85
  • TAS6417

    CAS:
    Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.
    Fórmula:C23H20N6O
    Pureza:99.71%
    Forma y color:Solid
    Peso molecular:396.44