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Angiogénesis

Angiogénesis

Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.

Subcategorías de "Angiogénesis"

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Se han encontrado 2121 productos de "Angiogénesis"

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  • Vactosertib Hydrochloride

    CAS:
    Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an ALK5 inhibitor, a TGF-β receptor I inhibitor with antimetastatic and anticancer effects.
    Fórmula:C22H19ClFN7
    Pureza:98.03%
    Forma y color:Solid
    Peso molecular:435.89
  • Endoxifen (Z-isomer)

    CAS:
    Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.
    Fórmula:C25H27NO2
    Pureza:99.19% - 99.81%
    Forma y color:Solid
    Peso molecular:373.49
  • NVP-TAE 226

    CAS:
    NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.
    Fórmula:C23H25ClN6O3
    Pureza:98.07% - 98.78%
    Forma y color:Solid
    Peso molecular:468.94
  • PF-562271

    CAS:
    PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
    Fórmula:C21H20F3N7O3S
    Pureza:97.17% - >99.99%
    Forma y color:Solid
    Peso molecular:507.49
  • NRC-2694

    CAS:
    NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.
    Fórmula:C24H26N4O3
    Pureza:99.90%
    Forma y color:Solid
    Peso molecular:418.49
  • Nocodazole

    CAS:
    Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.
    Fórmula:C14H11N3O3S
    Pureza:98% - 99.91%
    Forma y color:Physical Description White Powder (Ntp 1992)
    Peso molecular:301.32
  • WS3

    CAS:
    WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.
    Fórmula:C28H30F3N7O3
    Pureza:97.93% - 99.94%
    Forma y color:Solid
    Peso molecular:569.58
  • CP-380736

    CAS:
    CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.
    Fórmula:C14H18N2O5
    Pureza:99.68%
    Forma y color:White To Off-White Solid
    Peso molecular:294.3
  • URMC-099

    CAS:
    URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.
    Fórmula:C27H27N5
    Pureza:99.32% - 99.98%
    Forma y color:Solid
    Peso molecular:421.54
  • AG-1557 hydrochloride (189290-58-2(free base))


    AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
    Fórmula:C16H15ClIN3O2
    Pureza:98.64%
    Forma y color:Solid
    Peso molecular:443.66
  • (E)-AG 99

    CAS:
    (E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).
    Fórmula:C10H8N2O3
    Pureza:99.23%
    Forma y color:Solid
    Peso molecular:204.18
  • Osimertinib

    CAS:
    Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.
    Fórmula:C28H33N7O2
    Pureza:99.32% - >99.99%
    Forma y color:Solid
    Peso molecular:499.61
  • Alectinib

    CAS:
    Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.
    Fórmula:C30H34N4O2
    Pureza:98% - 99.38%
    Forma y color:Solid
    Peso molecular:482.62
  • Lenvatinib mesylate

    CAS:
    Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.
    Fórmula:C22H23ClN4O7S
    Pureza:99.03% - 99.79%
    Forma y color:Solid
    Peso molecular:522.96
  • (Z)-Semaxinib

    CAS:
    (Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for
    Fórmula:C15H14N2O
    Pureza:98.82% - ≥95%
    Forma y color:Solid
    Peso molecular:238.28
  • Avitinib maleate

    CAS:
    Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.
    Fórmula:C30H30FN7O6
    Pureza:98% - 99.74%
    Forma y color:Solid
    Peso molecular:603.61
  • SU5204

    CAS:
    SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and
    Fórmula:C17H15NO2
    Pureza:99.46%
    Forma y color:Solid
    Peso molecular:265.31
  • Vatalanib free base

    CAS:
    Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).
    Fórmula:C20H15ClN4
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:346.81
  • (E/Z)-Zotiraciclib citrate


    (E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.
    Fórmula:C29H32N4O8
    Forma y color:Solid
    Peso molecular:564.59
  • Tyrphostin B44, (+) enantiomer

    CAS:
    Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)
    Fórmula:C18H16N2O3
    Pureza:97.18%
    Forma y color:Solid
    Peso molecular:308.33