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Angiogénesis

Angiogénesis

Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.

Subcategorías de "Angiogénesis"

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Se han encontrado 2121 productos de "Angiogénesis"

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  • Allitinib tosylate

    CAS:
    Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.
    Fórmula:C31H26ClFN4O5S
    Pureza:98.46% - 98.68%
    Forma y color:Solid
    Peso molecular:621.08
  • ENMD-2076

    CAS:
    ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
    Fórmula:C21H25N7
    Pureza:97.63% - ≥95%
    Forma y color:Solid
    Peso molecular:375.47
  • TL-895

    CAS:
    TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).
    Fórmula:C25H26FN5O2
    Pureza:99.96%
    Forma y color:Solid
    Peso molecular:447.5
  • ATH686

    CAS:
    ATH686 is an potent and selective Inhibitor of FLT3.
    Fórmula:C25H28F3N7O2
    Pureza:98.07%
    Forma y color:Solid
    Peso molecular:515.53
  • RK-24466

    CAS:
    RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.
    Fórmula:C23H22N4O
    Pureza:98.07%
    Forma y color:Solid
    Peso molecular:370.45
  • Flumatinib

    CAS:
    Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.
    Fórmula:C29H29F3N8O
    Pureza:99.39% - 99.95%
    Forma y color:Solid
    Peso molecular:562.59
  • EGFR-IN-12

    CAS:
    EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
    Fórmula:C21H18F3N5O
    Pureza:98.3% - 99.76%
    Forma y color:Solid
    Peso molecular:413.4
  • HA 155

    CAS:
    HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
    Fórmula:C24H19BFNO5S
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:463.29
  • Vatalanib dihydrochloride

    CAS:
    Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.
    Fórmula:C20H15ClN4·2HCl
    Pureza:99.16%
    Forma y color:White To Off-White Crystalline Powder
    Peso molecular:419.73
  • PD173074

    CAS:
    PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.
    Fórmula:C28H41N7O3
    Pureza:98.15% - 98.21%
    Forma y color:Yellow Solid
    Peso molecular:523.67
  • AZ7550

    CAS:
    AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
    Fórmula:C27H31N7O2
    Pureza:97.07% - 99.75%
    Forma y color:Solid
    Peso molecular:485.58
  • PRN1371

    CAS:
    PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).
    Fórmula:C26H30Cl2N6O4
    Pureza:98.65%
    Forma y color:Solid
    Peso molecular:561.46
  • HPK1-IN-2

    CAS:
    HPK1-IN-2 is a strong, oral HPK1 inhibitor (IC50<0.05 μM), also blocking Lck, Flt3 kinases, with anticancer properties.
    Fórmula:C19H20N6OS
    Pureza:97.31%
    Forma y color:Solid
    Peso molecular:380.47
  • KW-2449

    CAS:
    KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.
    Fórmula:C20H20N4O
    Pureza:98.43% - 99.69%
    Forma y color:Solid
    Peso molecular:332.4
  • Fruquintinib

    CAS:
    Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-
    Fórmula:C21H19N3O5
    Pureza:98.84% - 99.89%
    Forma y color:Solid
    Peso molecular:393.39
  • S49076

    CAS:
    S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.
    Fórmula:C22H22N4O4S
    Pureza:95.35% - 97.4%
    Forma y color:Solid
    Peso molecular:438.5
  • AZD2932

    CAS:
    AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.
    Fórmula:C24H25N5O4
    Pureza:97.71% - 98.37%
    Forma y color:Solid
    Peso molecular:447.49
  • Golvatinib

    CAS:
    Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor
    Fórmula:C33H37F2N7O4
    Pureza:98.24% - ≥95%
    Forma y color:Solid
    Peso molecular:633.69
  • EOC317

    CAS:
    EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).
    Fórmula:C27H26F5N7O3
    Pureza:98.00% - 99.26%
    Forma y color:Solid
    Peso molecular:591.53
  • Compound Lup-20(29)-en-3-yl acetate


    <p>Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.</p>
    Fórmula:C32H52O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:468.75