Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(154 productos)
- Bcr-Abl(111 productos)
- EGFR(591 productos)
- FAK(71 productos)
- FLT(87 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(173 productos)
- JAK(245 productos)
- PDGFR(126 productos)
- RAAS(89 productos)
- Src(81 productos)
- Syk(37 productos)
- Trombina(52 productos)
- VDA(2 productos)
- VEGFR(253 productos)
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Se han encontrado 1884 productos de "Angiogénesis"
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EGFR-IN-59
CAS:<p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>Fórmula:C27H23N5O4SForma y color:SolidPeso molecular:513.57EAI001
CAS:EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.Fórmula:C19H15N3O2SPureza:99.94%Forma y color:SolidPeso molecular:349.41RIPK2-IN-1
CAS:RIPK2-IN-1 (compound 18f) is a potent inhibitor of RIPK2 (IC50: 51 nM) and also inhibits ALK2 (IC50: 5 nM).Fórmula:C23H27N5O3SForma y color:SolidPeso molecular:453.56ALK-IN-22
CAS:ALK-IN-22 suppresses ALK and mutants (IC50: 2.3-3.7 nM), hinders phosphorylation, and induces apoptosis in tumor studies.Fórmula:C24H24ClN7O2Forma y color:SolidPeso molecular:477.95AG-370
CAS:<p>AG 370, an indole tyrphostin, functions as a powerful inhibitor of PDGF-induced mitogenesis, demonstrating an IC50 of 20 μM.</p>Fórmula:C15H9N5Forma y color:SolidPeso molecular:259.27CpCDPK1/TgCDPK1-IN-1
CAS:CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.Fórmula:C18H17N5Pureza:99.61%Forma y color:SolidPeso molecular:303.36FGFR3-IN-2
CAS:<p>FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor that inhibits FGFR3 (IC50: 4.1 nM) and VEGFR2 (IC50: 570 nM).</p>Fórmula:C28H39N9O4SForma y color:SolidPeso molecular:597.73ZK-304709 HCl
CAS:ZK-304709 is an oral multitarget tumor growth inhibitor with activity against cell-cycle progression and angiogenesis.Fórmula:C22H29ClN6O2Forma y color:SolidPeso molecular:444.96UniPR1331
CAS:UniPR1331 is a novel selective antagonist of the Eph-ephrin system.Fórmula:C35H48N2O4Forma y color:SolidPeso molecular:560.77BPIQ-II (hydrochloride)
CAS:BPIQ-II, a selective EGFR inhibitor with an IC50 of 8 pM, targets ATP sites and halts EGF signals inside cells.Fórmula:C15H11BrClN5Forma y color:SolidPeso molecular:376.64IHMT-TRK-284
CAS:IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Fórmula:C25H27N7OSForma y color:SolidPeso molecular:473.59TYRA-200
CAS:TYRA-200 is an effective oral inhibitor of FGFR1/2/3. In both wild-type FGFR2 and FGFR2 mutant models, TYRA-200 can produce tumor regression effects in a dose-dependent manner. TYRA-200 can be used in the research of advanced or metastatic intrahepatic cholangiocarcinoma and other solid tumors driven by FGFR2.Fórmula:C23H24FN7O2Peso molecular:449.48PDGFR-IN-1
CAS:PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Fórmula:C25H30N8OPureza:99.13% - 99.49%Forma y color:SolidPeso molecular:458.56JNJ-64264681
CAS:JNJ-64264681 is a potent, orally active, selective, and irreversible covalent inhibitor of Bruton's tyrosine kinase (BTK).Fórmula:C27H30N6O3SPureza:98%Forma y color:SolidPeso molecular:518.63CS12192
CAS:CS12192 enhances survival, boosts weight, and shows promise in GVHD research per patent CN112773802A.Fórmula:C25H23ClFN7O2Forma y color:SolidPeso molecular:507.95PDE5-IN-3
CAS:PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.Fórmula:C21H14BrN5O2Forma y color:SolidPeso molecular:448.27NSC81111
CAS:NSC81111 shows anticaner effects which is a potent and orally active inhibitor of EGFR-TK (IC50 = 0.15 nM) [1].Fórmula:C19H16O4Forma y color:SolidPeso molecular:308.33AFN941
CAS:AFN941 is a staurosporine analog, acting as a Jak3-specific inhibitor.Fórmula:C28H30N4O3Forma y color:SolidPeso molecular:470.56RK-20448
CAS:RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2. It also inhibits BLK, Csk, Fyn, and Lyn. RK-20448 is the cis isomer of A-419259Fórmula:C29H34N6OForma y color:SolidPeso molecular:482.62TYK2-IN-12
CAS:TYK2-IN-12: selective oral TYK2 inhibitor (Ki: 0.51 nM), blocks IL-12-induced IFNγ; IC50: human 2.7 µM, mouse 7.0 µM, used for psoriasis research.Fórmula:C24H20F2N4O2Forma y color:SolidPeso molecular:434.44
