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Angiogénesis

Angiogénesis

Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.

Subcategorías de "Angiogénesis"

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Se han encontrado 1522 productos de "Angiogénesis"

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  • BPIQ-I

    CAS:
    <p>BPIQ-I (PD 159121), an ATP-competitive EGFR tyrosine kinase inhibitor, exhibits potent anti-proliferative activity.</p>
    Fórmula:C16H12BrN5
    Forma y color:Solid
    Peso molecular:354.2
  • Nazartinib S-enantiomer

    CAS:
    <p>Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.</p>
    Fórmula:C26H31ClN6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:495.02
  • EGFR-IN-32

    CAS:
    <p>EGFR-IN-32, a potent EGFR blocker, shows promise for EGFR-mutated illnesses. (Patent WO2021185297A1, compound 2)</p>
    Fórmula:C31H34N6O3
    Forma y color:Solid
    Peso molecular:538.64
  • HDAC-IN-63

    CAS:
    <p>HDAC-IN-63 (Compound 63) is a dual FLT3/HDAC inhibitor with IC50 values of 0.844 nM for FLT3 and 30.0 nM for HDAC1.</p>
    Fórmula:C25H26Cl2N6O3
    Forma y color:Solid
    Peso molecular:529.42
  • KB SRC 4

    CAS:
    KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.CAS 번호13460-73-83-4
    Fórmula:C32H23ClN8
    Pureza:98.83% - 99.34%
    Forma y color:Solid
    Peso molecular:555.03
  • PI3K/VEGFR2-IN-1

    CAS:
    <p>PI3K/VEGFR2-IN-1 is a potent dual inhibitor targeting both PI3K and VEGFR2 with IC50 values of 2.21 μM for PI3K and 68 μM for VEGFR2, respectively.</p>
    Fórmula:C17H14ClN3OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:343.83
  • Sulfatinib

    CAS:
    <p>Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to</p>
    Fórmula:C24H28N6O3S
    Pureza:99.21% - >99.99%
    Forma y color:Solid
    Peso molecular:480.58
  • DZD1516

    CAS:
    <p>DZD1516, a potent and selective HER2 inhibitor (IC50 = 0.56 nM), demonstrates good blood-brain barrier permeability and exhibits antitumor activity in both</p>
    Fórmula:C28H27F2N7O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:547.56
  • TIE-2/VEGFR-2 kinase-IN-5

    CAS:
    TIE-2/VEGFR-2 kinase-IN-5 is a TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor commonly used in biomedical research related to angiogenesis.
    Fórmula:C21H13F6N5O2
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:481.35
  • Upadacitinib tartrate

    CAS:
    <p>Upadacitinib: potent, selective JAK1 inhibitor, 74x preferential to JAK2, effective in rat arthritis.</p>
    Fórmula:C21H33F3N6O11
    Pureza:98%
    Forma y color:Solid
    Peso molecular:602.521
  • EGFR-IN-74


    <p>EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM.</p>
    Fórmula:C32H28BrF3N6O4S
    Forma y color:Solid
    Peso molecular:729.57
  • FLT3/ITD-IN-4

    CAS:
    <p>FLT3/ITD-IN-4 inhibits FLT3-ITD mutations in acute myeloid leukemia (IC50: 2.3 nM).</p>
    Fórmula:C25H22N4O5
    Forma y color:Solid
    Peso molecular:458.47
  • EGFR-IN-30

    CAS:
    <p>EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, &lt;1 nM WT/mutants) with potential in cancer research.</p>
    Fórmula:C28H33BrN7O2P
    Forma y color:Solid
    Peso molecular:610.49
  • FGFR-IN-2

    CAS:
    <p>FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).</p>
    Fórmula:C25H30N6O2
    Forma y color:Solid
    Peso molecular:446.54
  • IN-1130

    CAS:
    <p>IN-1130: ALK5 inhibitor, IC50 - 5.3 nM (Smad3), 36 nM (casein), 4.3 μM (p38α MAPK).</p>
    Fórmula:C25H20N6O
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:420.47
  • Sevabertinib

    CAS:
    <p>Sevabertinib (BAY 2927088) is an EGFR tyrosine kinase inhibitor, with anticancer activity, used in research on non-small cell lung cancer.</p>
    Fórmula:C24H25ClN4O5
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:484.93
  • BMS-935177

    CAS:
    <p>BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.</p>
    Fórmula:C31H26N4O3
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:502.56
  • KER047

    CAS:
    ALK2-IN-4, a highly effective ALK2 inhibitor.
    Fórmula:C26H30FN7O
    Pureza:98.49% - >99.99%
    Forma y color:Solid
    Peso molecular:475.56
  • Zongertinib

    CAS:
    <p>Zongertinib is a human HER2-selective tyrosine kinase inhibitor, a novel TK that is highly selective for covalent binding to the HER2 tyrosine kinase domain (</p>
    Fórmula:C29H29N9O2
    Pureza:98.24%
    Forma y color:Solid
    Peso molecular:535.6
  • Ifebemtinib

    CAS:
    Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.
    Fórmula:C28H28F4N6O4
    Pureza:98.84% - 99.85%
    Forma y color:Solid
    Peso molecular:588.55