Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(161 productos)
- Bcr-Abl(116 productos)
- EGFR(595 productos)
- FAK(72 productos)
- FLT(90 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(183 productos)
- JAK(247 productos)
- PDGFR(126 productos)
- RAAS(90 productos)
- Src(81 productos)
- Syk(37 productos)
- Trombina(53 productos)
- VDA(2 productos)
- VEGFR(246 productos)
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Se han encontrado 2141 productos de "Angiogénesis"
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R-932348 choline
CAS:R-932348 choline, a dual JAK/SYK inhibitor, is used potentially for treatment of dry eye disease.Fórmula:C28H35FN6O5SPureza:98%Forma y color:SolidPeso molecular:586.68PDE5-IN-3
CAS:PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.Fórmula:C21H14BrN5O2Forma y color:SolidPeso molecular:448.27Z118332870
CAS:Z118332870 is a potent inhibitor of EGFR and BRD4.Fórmula:C18H18FN3O3Forma y color:SolidPeso molecular:343.35TYK2-IN-12
CAS:TYK2-IN-12: selective oral TYK2 inhibitor (Ki: 0.51 nM), blocks IL-12-induced IFNγ; IC50: human 2.7 µM, mouse 7.0 µM, used for psoriasis research.Fórmula:C24H20F2N4O2Forma y color:SolidPeso molecular:434.44BCR-ABL-IN-7
CAS:BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.Fórmula:C19H16FN3O3SPureza:98.28%Forma y color:SolidPeso molecular:385.41PF-6422899
CAS:PF-6422899 irreversibly inhibits EGFR kinase activity by binding covalently to active-site cysteine residues in the ATP binding pocket of EGFR.Fórmula:C20H14ClFN4O2Forma y color:SolidPeso molecular:396.8MJ04
CAS:MJ04 is a selective inhibitor of Janus Kinase 3 (JAK3) with an IC50 of 2.03 nM. It hinders T cell differentiation and suppresses pro-inflammatory cytokines in macrophages induced by Lipopolysaccharides. In mice, MJ04 exhibits favorable pharmacokinetic properties and promotes hair growth in a DHT-induced alopecia model in athymic mice, without notable toxicity (LD50>2 g/kg).Fórmula:C20H16FN5Forma y color:SolidPeso molecular:345.37OD36 hydrochloride
CAS:OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficientlyFórmula:C16H16Cl2N4O2Pureza:99.85%Forma y color:SolidPeso molecular:367.23KBP-7018 HCl
CAS:KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).Fórmula:C31H31ClN4O5Forma y color:SolidPeso molecular:575.06TG-46
CAS:TG-46 (TG46) inhibits JAK2, FLT3, RET, JAK3 and can be used to study glaucoma.Fórmula:C26H34N6O3SPureza:98.82% - 99.86%Forma y color:SolidPeso molecular:510.65PF-06672131
CAS:PF-06672131 is a selective EGFR kinase inhibitor.Fórmula:C23H21ClFN5O2Forma y color:SolidPeso molecular:453.9Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Fórmula:C27H31N9O5Pureza:98%Forma y color:SolidPeso molecular:561.59Esuberaprost Sodium
CAS:<p>Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.</p>Fórmula:C23H27FN4O2Forma y color:SolidPeso molecular:410.48MS 154N
CAS:<p>MS 154N is a negative control for MS 154, binds WT/L858R EGFR tightly (Kd 3-4.3nM), doesn't trigger mutant EGFR degradation.</p>Fórmula:C47H56ClFN8O8Forma y color:SolidPeso molecular:915.45c-ABL-IN-2
CAS:C-ABL-IN-2 is a potent c-Abl protein inhibitor, promising for research in cancer and neurodegenerative diseases like ALS and PD.Fórmula:C21H20N4OForma y color:SolidPeso molecular:344.41NAMI-A
CAS:NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.Fórmula:C8H15Cl4N4ORuSPureza:98%Forma y color:SolidPeso molecular:458.18Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Fórmula:C24H30N6O3SPureza:99.71%Forma y color:SolidPeso molecular:482.6ALK5-IN-26
CAS:ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 (IC50 ≤ 1 nM).Fórmula:C24H25FN8Forma y color:SolidPeso molecular:444.51EGFR-IN-73
CAS:EGFR-IN-73 (Compound 3f) effectively inhibits the prevalent EGFR mutation, EGFR Del19, exhibiting an IC50 value of 119 nM [1].Fórmula:C19H17ClFN3O4Pureza:98%Forma y color:SolidPeso molecular:405.81ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFórmula:C20H22N2O5Pureza:98%Forma y color:SolidPeso molecular:370.4
