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Angiogénesis

Angiogénesis

Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.

Subcategorías de "Angiogénesis"

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Se han encontrado 2121 productos de "Angiogénesis"

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  • Mutated EGFR-IN-3
    Targetmol
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    Mutated EGFR-IN-3

    CAS:
    Mutated EGFR-IN-3: ATP-competitive, selective dibenzodiazepinone inhibitor for EGFR mutations, IC50 12-13 nM.
    Fórmula:C31H29FN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:508.59

    Ref: TM-T12131

  • ALK5-IN-30
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    ALK5-IN-30

    CAS:
    ALK5-IN-30 (EX-07) is a potent inhibitor of ALK with inhibitory effects on ALK5 (IC50< 10 nM) and TGFβ-R1 (IC50< 10 nM).
    Fórmula:C24H25FN8
    Forma y color:Solid
    Peso molecular:444.51

    Ref: TM-T62615

  • MMPP
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    MMPP

    CAS:
    MMPP is a VEGFR2 inhibitor with anti-inflammatory activity, inhibits STAT3 , inhibits angiogenesis, and can be used to alleviate myocardial injury.
    Fórmula:C17H18O3
    Pureza:99.31% - 99.83%
    Forma y color:Solid
    Peso molecular:270.32

    Ref: TM-T28077

  • RIPK2-IN-1
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    RIPK2-IN-1

    CAS:
    RIPK2-IN-1 (compound 18f) is a potent inhibitor of RIPK2 (IC50: 51 nM) and also inhibits ALK2 (IC50: 5 nM).
    Fórmula:C23H27N5O3S
    Forma y color:Solid
    Peso molecular:453.56

    Ref: TM-T62783

  • FLT3-IN-6
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    FLT3-IN-6

    CAS:
    FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM.
    Fórmula:C23H25N5O3
    Forma y color:Solid
    Peso molecular:419.48

    Ref: TM-T11300

  • EGFR-IN-59
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    EGFR-IN-59

    CAS:
    EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.
    Fórmula:C27H23N5O4S
    Forma y color:Solid
    Peso molecular:513.57

    Ref: TM-T63556

  • ALK5-IN-29
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    ALK5-IN-29

    CAS:
    <p>ALK5-IN-29: selective ALK inhibitor, IC50 ≤ 10 nM, curbs tumor growth, aids in cancer research.</p>
    Fórmula:C24H25FN8
    Forma y color:Solid
    Peso molecular:444.51

    Ref: TM-T62614

  • MBM-55S
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    MBM-55S

    CAS:
    MBM-55S, a Nek2 inhibitor with 1 nM IC50, induces cell cycle arrest and apoptosis, suppressing tumor growth.
    Fórmula:C36H39FN6O10
    Pureza:99.37% - 99.89%
    Forma y color:Solid
    Peso molecular:734.73

    Ref: TM-T11961

  • BMS-243117
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    BMS-243117

    CAS:
    BMS-243117: Selective LCK inhibitor, IC50=1.1µM, inhibits T cell growth, promising for immunosuppression, arthritis, asthma treatment.
    Fórmula:C20H21ClN4O2S
    Forma y color:Solid
    Peso molecular:416.92

    Ref: TM-T30508

  • RET-IN-19
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    RET-IN-19

    CAS:
    RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.
    Fórmula:C28H28N6O4S
    Forma y color:Solid
    Peso molecular:544.62

    Ref: TM-T63837

  • XST-14
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    XST-14

    CAS:
    XST-14 is a ULK1 inhibitor.XST-14 induces apoptosis and inhibits the growth of HCC cells.
    Fórmula:C16H21NO4
    Pureza:99.84% - 99.84%
    Forma y color:Solid
    Peso molecular:291.34

    Ref: TM-T60604

  • Aminoquinuride
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    Aminoquinuride

    CAS:
    Surfen, or Aminoquinuride, reduces inflammation but blocks remyelination in MS mouse models and regulates murine T cell activation.
    Fórmula:C21H20N6O
    Forma y color:Solid
    Peso molecular:372.42

    Ref: TM-T69320

  • Y 11
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    Y 11

    CAS:
    focal adhesion kinase (FAK) inhibitor
    Fórmula:C8H17BrN4O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:265.15

    Ref: TM-T23539

  • JNJ28871063 hydrochloride
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    JNJ28871063 hydrochloride

    CAS:
    ErbB receptor family inhibitor
    Fórmula:C24H28Cl2N6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:519.42

    Ref: TM-T22881

  • TyK2-IN-2
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    TyK2-IN-2

    CAS:
    TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).
    Fórmula:C16H18N6O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:310.35

    Ref: TM-T13232

  • Z118332870
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    Z118332870

    CAS:
    Z118332870 is a potent inhibitor of EGFR and BRD4.
    Fórmula:C18H18FN3O3
    Forma y color:Solid
    Peso molecular:343.35

    Ref: TM-T29199

  • HKI-357 dimaleate
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    HKI-357 dimaleate

    CAS:
    HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
    Fórmula:C39H37ClFN5O11
    Forma y color:Solid
    Peso molecular:806.2

    Ref: TM-T68360

  • EGFR-IN-46
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    EGFR-IN-46

    CAS:
    EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.
    Fórmula:C27H32F3N3O3
    Forma y color:Solid
    Peso molecular:503.56

    Ref: TM-T63431

  • CJ-2360
    Targetmol
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    CJ-2360

    CAS:
    CJ-2360 is a potent ALK inhibitor, effective on wild-type and various mutants, with IC50 values ranging from 2.2 to 8.9 nM, also targeting 468 kinases.
    Fórmula:C27H30FN5O2
    Forma y color:Solid
    Peso molecular:475.56

    Ref: TM-T63101

  • VA5 TG2 inhibitor
    Targetmol
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    VA5 TG2 inhibitor

    CAS:
    VA5 inhibits transamidase and GTP-binding by locking protein in an open state, disabling GTPase.
    Fórmula:C31H34N4O8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:590.62

    Ref: TM-T29086