Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(159 productos)
- Bcr-Abl(115 productos)
- EGFR(593 productos)
- FAK(72 productos)
- FLT(89 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(182 productos)
- JAK(246 productos)
- PDGFR(126 productos)
- RAAS(90 productos)
- Src(81 productos)
- Syk(37 productos)
- Trombina(53 productos)
- VDA(2 productos)
- VEGFR(247 productos)
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Se han encontrado 2121 productos de "Angiogénesis"
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NSC81111
CAS:NSC81111 shows anticaner effects which is a potent and orally active inhibitor of EGFR-TK (IC50 = 0.15 nM) [1].Fórmula:C19H16O4Forma y color:SolidPeso molecular:308.33Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Fórmula:C29H38FN3O5Pureza:97.07% - 98.07%Forma y color:SolidPeso molecular:527.63DMPQ dihydrochloride
CAS:PDGFRβ inhibitorFórmula:C16H16Cl2N2O2Pureza:99.51%Forma y color:SolidPeso molecular:339.22Naphazoline
CAS:Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.Fórmula:C14H14N2Pureza:99.79%Forma y color:White Crystalline Powder SolidPeso molecular:210.27ARQ 069
CAS:ARQ 069 inhibits FGFR2 phosphorylation concentration-dependently (IC50: 9.7 µM), without affecting β-actin. Preferentially binds inactive FGFR1/2.Fórmula:C18H15N3Pureza:98%Forma y color:SolidPeso molecular:273.33BTK-IN-9
CAS:BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.Fórmula:C25H19N7O4Forma y color:SolidPeso molecular:481.46BCR-ABL-IN-7
CAS:BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.Fórmula:C19H16FN3O3SPureza:98.28%Forma y color:SolidPeso molecular:385.41PF-6422899
CAS:PF-6422899 irreversibly inhibits EGFR kinase activity by binding covalently to active-site cysteine residues in the ATP binding pocket of EGFR.Fórmula:C20H14ClFN4O2Forma y color:SolidPeso molecular:396.8MJ04
CAS:MJ04 is a selective inhibitor of Janus Kinase 3 (JAK3) with an IC50 of 2.03 nM. It hinders T cell differentiation and suppresses pro-inflammatory cytokines in macrophages induced by Lipopolysaccharides. In mice, MJ04 exhibits favorable pharmacokinetic properties and promotes hair growth in a DHT-induced alopecia model in athymic mice, without notable toxicity (LD50>2 g/kg).Fórmula:C20H16FN5Forma y color:SolidPeso molecular:345.37AC710 Mesylate
CAS:AC710 Mesylate is a potent PDGFR inhibitor (Kds: 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ).Fórmula:C32H46N6O7SPureza:98%Forma y color:SolidPeso molecular:658.81THS-044
CAS:THS-044 (N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine) binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activityFórmula:C11H12F3N3O3Pureza:99.89%Forma y color:SolidPeso molecular:291.23RTC-5
CAS:RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties.Fórmula:C24H22ClF3N2O3SPureza:98.14%Forma y color:SolidPeso molecular:510.96Cenisertib benzoate
CAS:Cenisertib benzoate is an orally bioavailable, synthetic, small-molecule multi-Aurora kinase inhibitor with potential antineoplastic activity.Fórmula:C31H36FN7O3Forma y color:SolidPeso molecular:573.66GDC-0834 S-enantiomer
CAS:GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK).Fórmula:C33H36N6O3SPureza:98%Forma y color:SolidPeso molecular:596.74VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.Fórmula:C26H20Cl2F3N5O3S2Forma y color:SolidPeso molecular:642.5A-420983
CAS:A-420983 is a novel potent Lck inhibitor, exhibiting oral efficacy in animal models of delayed-type hypersensitivity and organ transplant rejection.Fórmula:C33H39N9O2Forma y color:SolidPeso molecular:593.72ZD4190 HCl
CAS:ZD-4190, a potent VEGFR inhibitor, prevents tumour outgrowth in a model of minimal residual carcinoma in deep tissues.Fórmula:C19H17BrClFN6O2Pureza:98%Forma y color:SolidPeso molecular:495.73KBP-7018 HCl
CAS:KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).Fórmula:C31H31ClN4O5Forma y color:SolidPeso molecular:575.06AXL-IN-13
CAS:AXL-IN-13: potent, oral AXL inhibitor, IC50=1.6nM, Kd=0.26nM, anti-cancer, inhibits EMT, cell migration & invasion.Fórmula:C34H41FN6O5Pureza:99.95%Forma y color:SolidPeso molecular:632.72Tyrphostin 51
CAS:Tyrphostin 51 is an effective inhibitor of EGFR kinase.Fórmula:C13H8N4O3Pureza:98%Forma y color:SolidPeso molecular:268.23
