Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(159 productos)
- Bcr-Abl(115 productos)
- EGFR(593 productos)
- FAK(72 productos)
- FLT(89 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(182 productos)
- JAK(246 productos)
- PDGFR(126 productos)
- RAAS(90 productos)
- Src(81 productos)
- Syk(37 productos)
- Trombina(53 productos)
- VDA(2 productos)
- VEGFR(247 productos)
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Se han encontrado 2121 productos de "Angiogénesis"
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Sitravatinib malate
CAS:<p>Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5</p>Fórmula:C37H35F2N5O9SPureza:98%Forma y color:SolidPeso molecular:763.76VEGFR-2-IN-27
CAS:VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.Fórmula:C25H21FN4O4Forma y color:SolidPeso molecular:460.46Lck Inhibitor III
CAS:Lck Inhibitor III, a potent inhibitor of Lck, exhibits an IC50 value of 867 nM.Fórmula:C25H30N6O4Forma y color:SolidPeso molecular:478.54Gefitinib N-oxide
CAS:Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib N-oxide is the N-oxide derivative of Gefitinib.Fórmula:C22H24ClFN4O4Pureza:98%Forma y color:SolidPeso molecular:462.9CP-547632 hydrochloride
CAS:CP-547632 hydrochloride: oral VEGFR-2/FGF inhibitor (IC50: 11/9 nM), well-tolerated, antitumor.Fórmula:C20H25BrClF2N5O3SForma y color:SolidPeso molecular:568.86EMI48
CAS:EMI48, a derivative of EMI1, exhibits increased efficacy against mutant EGFR compared to EMI1. It specifically inhibits EGFR triple mutants [1].Fórmula:C21H20N2O3Forma y color:SolidPeso molecular:348.4EGFR-IN-39
CAS:EGFR-IN-39, an acrylamide, is a potent EGFR inhibitor and antitumor agent targeting NSCLC with low toxicity. See WO2021185348A1 for details.Fórmula:C24H25ClN6O3Forma y color:SolidPeso molecular:480.95EGFR-IN-89
CAS:EGFR-IN-89 (compound 13k) is a fourth-generation inhibitor selectively targeting EGFR mutations, exhibiting potent activity with an IC50 of 10.1 nM againstFórmula:C26H31FN8O2SPureza:98%Forma y color:SolidPeso molecular:538.64PF-00337210
CAS:<p>PF-00337210, an oral VEGFR2 inhibitor, may hinder endothelial and tumor cell growth, reducing angiogenesis and potentially causing cancer cell death.</p>Fórmula:C26H27N3O5Forma y color:SolidPeso molecular:461.51VEGFR-2-IN-20
CAS:<p>VEGFR-2-IN-20 (Compound 7) is a highly effective VEGFR inhibitor with significant potential for cancer research [1].</p>Fórmula:C20H20N4O3SForma y color:SolidPeso molecular:396.46SB-220025 trihydrochloride
CAS:SB-220025 trihydrochloride is an effective and specific human p38 mitogen-activated protein kinase inhibitor.Fórmula:C18H22Cl3FN6Pureza:98%Forma y color:SolidPeso molecular:447.77WB-308
CAS:WB-308 is an EGFR inhibitor that acts by decreasing NSCLC cell proliferation and colony formation and causing G2/M arrest and apoptosis.Fórmula:C19H17FN2OPureza:98%Forma y color:SolidPeso molecular:308.35Tyrphostin AG 568
CAS:Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.Fórmula:C13H9N5O2Pureza:98%Forma y color:SolidPeso molecular:267.24Depatuxizumab mafodotin
CAS:Depatuxizumab mafodotin, an antibody-drug conjugate (ADC) targeting the epidermal growth factor receptor (EGFR), is utilized in cancer research [1].Forma y color:LiquidYH-306
CAS:<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Fórmula:C19H18N2O2Pureza:98.06%Forma y color:SolidPeso molecular:306.36EMI56
CAS:EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].Fórmula:C21H20N2O3Forma y color:SolidPeso molecular:348.4BMS-605541
CAS:<p>BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).</p>Fórmula:C19H17F2N5OSPureza:98.07%Forma y color:SolidPeso molecular:401.43LY 456236 hydrochloride
CAS:LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.Fórmula:C16H16ClN3O2Pureza:99.95%Forma y color:SolidPeso molecular:317.77Larotinib
CAS:Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.Fórmula:C24H26ClFN4O4Pureza:99.73%Forma y color:SolidPeso molecular:488.94EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Fórmula:C29H35N9O2SPureza:99.93%Forma y color:SolidPeso molecular:573.71
