Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(159 productos)
- Bcr-Abl(115 productos)
- EGFR(593 productos)
- FAK(72 productos)
- FLT(89 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(182 productos)
- JAK(246 productos)
- PDGFR(126 productos)
- RAAS(90 productos)
- Src(81 productos)
- Syk(37 productos)
- Trombina(53 productos)
- VDA(2 productos)
- VEGFR(247 productos)
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Se han encontrado 2121 productos de "Angiogénesis"
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CHMFL-EGFR-202
CAS:CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).Fórmula:C25H24ClN7O2Pureza:99.66%Forma y color:SolidPeso molecular:489.96CTA 056
CAS:CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Fórmula:C35H34N6OPureza:97.22% - 97.76%Forma y color:SolidPeso molecular:554.68TG-89
CAS:TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian andFórmula:C26H34N6O3SPureza:98.68%Forma y color:SolidPeso molecular:510.65TC-S 7009
CAS:TC-S 7009: Strong HIF-2α inhibitor (Kd 81 nM), weak for HIF-1α; disrupts dimerization & gene expression.Fórmula:C12H6ClFN4O3Pureza:99.46% - 99.71%Forma y color:SolidPeso molecular:308.65c-Fms-IN-3
CAS:c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Fórmula:C23H30N6OPureza:99.87%Forma y color:SolidPeso molecular:406.52Pz-1
CAS:Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.Fórmula:C26H26N6O2Pureza:99.89%Forma y color:SolidPeso molecular:454.52Dasatinib hydrochloride
CAS:Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Fórmula:C22H27Cl2N7O2SPureza:99.88% - 99.98%Forma y color:SolidPeso molecular:524.47Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Fórmula:C26H27NO6Pureza:98.99%Forma y color:SolidPeso molecular:449.5PP58
CAS:PP58 is an inhibitor of PDGFR, FGFR and Src family.Fórmula:C22H19Cl2N5O2Pureza:99.21%Forma y color:SolidPeso molecular:456.32Tafetinib
CAS:Tafetinib (SIM-010603) is a novel potent and orally available tyrosine kinase inhibitor with anti-angiogenic and anti-tumour activity.Fórmula:C24H29FN4O2Pureza:96.23%Forma y color:SolidPeso molecular:424.51SU16f
CAS:SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.Fórmula:C24H22N2O3Pureza:97.69%Forma y color:SolidPeso molecular:386.44HIF-2α-IN-3
CAS:HIF-2α-IN-3 is an allosteric inhibitor of HIF-2α (IC50: 0.4 μM; KD: 1.1 μM) with anticancer activity.Fórmula:C12H6ClN5O5Pureza:98.11%Forma y color:SolidPeso molecular:335.66VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Fórmula:C29H29ClF3N7OSPureza:99.95%Forma y color:SolidPeso molecular:616.1Defactinib hydrochloride
CAS:Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Fórmula:C20H22ClF3N8O3SPureza:98.06% - 98.78%Forma y color:SolidPeso molecular:546.95ARN25068
CAS:ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.Fórmula:C19H18N6SPureza:99.75%Forma y color:SolidPeso molecular:362.45(R)-Zanubrutinib
CAS:(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).Fórmula:C27H29N5O3Pureza:99.55%Forma y color:SolidPeso molecular:471.55P505-15 Acetate
CAS:<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Fórmula:C21H27N9O3Pureza:99.99%Forma y color:SolidPeso molecular:453.5TP0427736 hydrochloride
CAS:TP0427736 hydrochloride is a novel and selective ALK5 inhibitor, capable of inhibiting Smad2/3 phosphorylation in A549 cells.Fórmula:C14H11ClN4S2Pureza:98.99%Forma y color:SolidPeso molecular:334.85NX-2127
CAS:NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFórmula:C39H45N9O5Pureza:99.07%Forma y color:SolidPeso molecular:719.83MBM-55
CAS:MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.Fórmula:C28H27FN6O2Pureza:99.83%Forma y color:SolidPeso molecular:498.55
