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Angiogénesis

Angiogénesis

Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.

Subcategorías de "Angiogénesis"

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Se han encontrado 2121 productos de "Angiogénesis"

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  • Falnidamol

    CAS:
    Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.
    Fórmula:C18H19ClFN7
    Pureza:98.816%
    Forma y color:Solid
    Peso molecular:387.84
  • Butyzamide

    CAS:
    <p>Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.</p>
    Fórmula:C29H32Cl2N2O5S
    Pureza:99.51% - 99.83%
    Forma y color:Soild
    Peso molecular:591.55
  • JNJ-49095397

    CAS:
    <p>JNJ-49095397 (RV568) is a p38 MAPK-α and p38 MAPK-γ kinase inhibitor for the study of respiratory syncytial virus infection.</p>
    Fórmula:C34H36N6O4
    Pureza:98.33% - 99.04%
    Forma y color:Solid
    Peso molecular:592.69
  • A 419259 trihydrochloride

    CAS:
    A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).
    Fórmula:C29H37Cl3N6O
    Pureza:99.75% - 99.96%
    Forma y color:Solid
    Peso molecular:592
  • Tilfrinib

    CAS:
    Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.
    Fórmula:C17H13N3O
    Pureza:99.54%
    Forma y color:Solid
    Peso molecular:275.3
  • STS-E412

    CAS:
    STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.
    Fórmula:C15H15ClN4O2
    Pureza:99.01%
    Forma y color:Solid
    Peso molecular:318.76
  • PKI-166

    CAS:
    PKI-166: oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM), halts growth & spread of many human cancers, including pancreatic.
    Fórmula:C20H18N4O
    Pureza:99.2%
    Forma y color:Solid
    Peso molecular:330.38
  • BRD7389

    CAS:
    BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.
    Fórmula:C24H18N2O2
    Pureza:99.51%
    Forma y color:Solid
    Peso molecular:366.41
  • Rezivertinib

    CAS:
    Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.
    Fórmula:C27H30N6O3
    Pureza:99.26% - 99.98%
    Forma y color:Solid
    Peso molecular:486.57
  • CCT365623 hydrochloride

    CAS:
    CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.
    Fórmula:C18H18ClNO4S3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:443.99
  • MS 154

    CAS:
    MS 154 is a potent PROTAC® targeting mutant EGFR in lung cancer, sparing WT-EGFR; effective in mice, with DC50 of 11-25 nM.
    Fórmula:C46H54ClFN8O8
    Forma y color:Solid
    Peso molecular:901.42
  • HPK1-IN-2 dihydrochloride

    CAS:
    HPK1-IN-2 dihydrochloride, a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1) with an IC 50 of less than 0.05 µM, demonstrates significant antitumor activity. It additionally exhibits inhibition of Lck kinase activity, with an IC 50 ranging from 0.05 to less than 0.5 µM, and Flt3 kinase activity, with an IC 50 of less than 0.05 µM [1].
    Fórmula:C19H22Cl2N6OS
    Forma y color:Solid
    Peso molecular:453.39
  • VEGFR-2-IN-37

    CAS:
    VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.
    Fórmula:C18H16N2O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:324.4
  • Cremastranone

    CAS:
    Cremastranone: natural homoisoflavanone that hinders human retinal cell proliferation, migration, and tube creation.
    Fórmula:C18H18O7
    Forma y color:Solid
    Peso molecular:346.33
  • BMS-599626 Hydrochloride

    CAS:
    BMS-599626 HCl (AC480 HCl) is an oral inhibitor of HER1, HER2, HER4 kinases, potentially blocking tumor growth. IC50: 22/32/190 nM.
    Fórmula:C27H28ClFN8O3
    Pureza:99.98%
    Forma y color:Solid
    Peso molecular:567.01
  • FGFR-IN-4

    CAS:
    FGFR-IN-4 is a potent inhibitor of FGFR. FGFR-IN-4 has potential for cancer disease studies.
    Fórmula:C24H21N7O2
    Forma y color:Solid
    Peso molecular:439.47
  • BMX-IN-1

    CAS:
    BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine
    Fórmula:C29H24N4O4S
    Pureza:98.38%
    Forma y color:Solid
    Peso molecular:524.59
  • BTK inhibitor 13

    CAS:
    BTK inhibitor 13 (compound 8) is an effective and selective BTK inhibitor(IC50: 1.2 nM).
    Fórmula:C29H26FN5O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:511.55
  • Pivanex

    CAS:
    Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.
    Fórmula:C10H18O4
    Pureza:≥98%
    Forma y color:Solid
    Peso molecular:202.25
  • OTS447

    CAS:
    OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .
    Fórmula:C27H32ClN3O2
    Pureza:98.78%
    Forma y color:Solid
    Peso molecular:466.02