Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(159 productos)
- Bcr-Abl(115 productos)
- EGFR(594 productos)
- FAK(72 productos)
- FLT(90 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(182 productos)
- JAK(246 productos)
- PDGFR(126 productos)
- RAAS(90 productos)
- Src(81 productos)
- Syk(37 productos)
- Trombina(53 productos)
- VDA(2 productos)
- VEGFR(249 productos)
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Se han encontrado 2061 productos de "Angiogénesis"
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AT-9283 L-lactate
CAS:AT-9283 L-lactate is an inhibitor of aurora kinase.Fórmula:C22H29N7O5Pureza:98%Forma y color:SolidPeso molecular:471.52(Z)-RG-13022
CAS:(Z)-RG-13022 is a tyrosine kinase (TK) inhibitor that preferentially inhibits the TK activity of the EGF receptor, restricting the EGF-stimulated growth of cultured cells. It demonstrates an IC50 of 11 μM for DNA synthesis in HN5 cells, showcasing thrice the potency of its isomer, (E)-RG-13022 (IC50 = 38 μM). This compound is applied in breast cancer cell research [1] [2].Fórmula:C16H14N2O2Forma y color:SolidPeso molecular:266.29Irpagratinib
CAS:<p>Irpagratinib (ABSK011) is an FGFR4 antagonist with anticancer activity, inhibiting FGFR4 autophosphorylation and blocking downstream signaling pathways.</p>Fórmula:C28H32F2N6O5Pureza:99.08% - 99.38%Forma y color:SolidPeso molecular:570.59Nezulcitinib
CAS:Nezulcitinib (TD-0903) is an inhaled pan-JAK inhibitor targeting COVID-19-related acute lung injury.Fórmula:C30H37N7O2Forma y color:SolidPeso molecular:527.66HIF-2α-IN-1
CAS:HIF-2α-IN-1 is a potent HIF-2α inhibitor with IC50 values less than 500 nM.Fórmula:C16H8F5NO4SPureza:97.99%Forma y color:SolidPeso molecular:405.3Roslin 2 bromide
CAS:Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5.Fórmula:C13H19BrN4Pureza:99.34%Forma y color:SolidPeso molecular:311.22PF-303
CAS:PF-303, a reversible covalent BTK inhibitor, shows potential for cancer and autoimmune therapy.Fórmula:C22H21ClN6O2Forma y color:SolidPeso molecular:436.89JNJ-17029259
CAS:JNJ-17029259 is an orally selective, potent inhibitors of the vascular endothelial growth factor receptor-2 (VEGF-R2).Fórmula:C26H30N6OPureza:98%Forma y color:SolidPeso molecular:442.56IN-1130
CAS:IN-1130: ALK5 inhibitor, IC50 - 5.3 nM (Smad3), 36 nM (casein), 4.3 μM (p38α MAPK).Fórmula:C25H20N6OPureza:99.79%Forma y color:SolidPeso molecular:420.47EGFR-IN-1 hydrochloride
CAS:EGFR-IN-1 HCl targets L858R/T790M EGFR mutants over wild-type; IC50: 4 nM in H1975, 28 nM in mutant HCC827 cells.Fórmula:C28H31ClN6O4Pureza:99.16%Forma y color:SolidPeso molecular:551.04BMS-935177
CAS:BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.Fórmula:C31H26N4O3Pureza:99.89%Forma y color:SolidPeso molecular:502.56ALK-IN-27
CAS:Neladalkib (NVL-655) is an ALK inhibitor with antitumor activity for the study of non-small cell cancers.Fórmula:C23H22ClFN6OPureza:99.71%Forma y color:SolidPeso molecular:452.91Sevabertinib
CAS:Sevabertinib (BAY 2927088) is an EGFR tyrosine kinase inhibitor, with anticancer activity, used in research on non-small cell lung cancer.Fórmula:C24H25ClN4O5Pureza:99.81%Forma y color:SolidPeso molecular:484.93Ifebemtinib
CAS:Ifebemtinib (BI-853520) is an adhesion plaque kinase inhibitor with anti-tumour activity for the study of breast cancer.Fórmula:C28H28F4N6O4Pureza:98.84% - 99.85%Forma y color:SolidPeso molecular:588.55EGFR-IN-87
CAS:EGFR-IN-87 is an EGFR tyrosine kinase inhibitor with potent inhibitory activity, exhibiting IC50 values of 3.1 nM, 1.3 nM, and 7.1 nM against EGFR_d746-750,Fórmula:C28H33N7O2Pureza:98.64%Forma y color:SolidPeso molecular:499.61KER047
CAS:ALK2-IN-4, a highly effective ALK2 inhibitor.Fórmula:C26H30FN7OPureza:98.49% - >99.99%Forma y color:SolidPeso molecular:475.56CH6953755
CAS:CH6953755: oral YES1 kinase inhibitor, IC50 1.8 nM, potent, selective, anticancer, halts cell proliferation.Fórmula:C26H22F2N6O4SPureza:98.87%Forma y color:SolidPeso molecular:552.55Zongertinib
CAS:Zongertinib is a human HER2-selective tyrosine kinase inhibitor, a novel TK that is highly selective for covalent binding to the HER2 tyrosine kinase domain (Fórmula:C29H29N9O2Pureza:98.24%Forma y color:SolidPeso molecular:535.6TAK-020
CAS:TAK-020 is a potent covalent inhibitor of Btk with potential antitumor activity for the study of rheumatoid arthritis and immune-related diseases.Fórmula:C18H17N5O3Pureza:98.66%Forma y color:SolidPeso molecular:351.36HM43239
CAS:HM43239: oral FLT3 inhibitor; IC50: FLT3 WT 1.1nM, ITD 1.8nM, D835Y 1.0nM; blocks p-STAT5/p-ERK; affects SYK, JAK1/2, TAK1; halts leukemia cell growth.Fórmula:C29H33ClN6Pureza:99.7%Forma y color:SolidPeso molecular:501.07
