Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(141 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(138 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(14 productos)
- Survivin(14 productos)
- TNF(92 productos)
- c-RET(55 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 5865 productos de "Apoptosis"
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PROTAC c-Met degrader-6
PROTACc-Met degrader-6 is a potent and orally active c-Met PROTAC degrader. It effectively promotes the degradation of c-Met protein, with DC50 values of 0.52 nM in EBC-1 cells and 0.45 nM in Hs746T cells. This compound almost completely abolishes the migration and invasion capabilities of tumor cells, significantly induces apoptosis (apoptosis), and arrests the cell cycle at the G0/G1 phase. PROTACc-Met degrader-6 is useful for studying various cancers, including non-small cell lung cancer and gastric cancer.Forma y color:Odour SolidRK-10
CAS:RK-10 is a peptide that binds to PD-L1. After being conjugated with Cy5 or Biotin, RK-10 can be used to identify PD-L1-expressing tumors through flow cytometry or immunohistochemistry. It is applicable for research in detecting cancers such as non-small cell lung cancer (NSCLC), breast cancer, squamous cell carcinoma, and melanoma.Fórmula:C105H176N28O36SForma y color:SolidPeso molecular:2438.75Lipustobart
CAS:<p>Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplastic</p>Pureza:98%Forma y color:LiquidMBC-11 trisodium
CAS:MBC-11 trisodium, a bisphosphonate-Ara-C conjugate, may treat TIBD.Fórmula:C11H17N3Na3O14P3Pureza:98%Forma y color:SolidPeso molecular:577.16NSD-IN-4
<p>NSD-IN-4 (Compound A8) is a potent and orally active inhibitor of NSD3, inducing apoptosis in a dose-dependent manner. It demonstrates significant antitumor activity against lung squamous cell carcinoma.</p>Fórmula:C17H12ClFN2O2Forma y color:SolidPeso molecular:330.741EGFR-IN-169
EGFR-IN-169 is an epidermal growth factor receptor (EGFR) inhibitor derived from ginsenoside, with an IC50 of 5.19 μM. It disrupts colorectal cancer cell migration and growth by inhibiting the EGFR-mediated RalA/EMT pathway. With an IC50 of 4.46 μM against HCT-116 cells and a selectivity index (SI) of 16.92, EGFR-IN-169 also inhibits CDKs, induces G0/G1 cell cycle arrest, and suppresses cell migration and invasion. Additionally, EGFR-IN-169 reduces mitochondrial membrane potential, induces apoptosis and reactive oxygen species (ROS) production. It is applicable in cancer research, particularly for colorectal cancer.Forma y color:Odour SolidIDOi-Pt(IV) prodrug-1
<p>IDOi-Pt(IV) prodrug-1 (Compound 10) is an IDOi-Pt(IV) prodrug that suppresses IDO expression. It induces apoptosis, reduces mitochondrial membrane potential, and inhibits tumor cell migration and invasion. Additionally, IDOi-Pt(IV) prodrug-1 triggers reactive oxygen species-mediated endoplasmic reticulum stress and the secretion of damage-associated molecular patterns (DAMPs), leading to immunogenic cell death (ICD). Compared to cisplatin, IDOi-Pt(IV) prodrug-1 exhibits relatively high efficiency and low toxicity in its antitumor activity.</p>Fórmula:C21H26Cl3N3O6PtSForma y color:SolidPeso molecular:749.96Anti-Mouse PD-1 Antibody (RMP1-14)
Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling. High-Quality, Low-Cost!Pureza:14.68mg/ml - >95%Forma y color:Odour LiquidAZD5153
CAS:AZD5153 is an orally active and selective BET/BRD4 bromodomain inhibitor with an IC50 value of 1.7nM for BRD4.Fórmula:C25H33N7O3Pureza:99.25%Forma y color:SolidPeso molecular:479.57Solanidine
CAS:Solanidine is a cholestane alkaloid isolated from potato species with antitumor effects. Solanidine inhibits proliferation.Fórmula:C27H43NOPureza:96.83%Forma y color:SolidPeso molecular:397.64Asudemotide
CAS:Asudemotide is a bioactive chemical.Fórmula:C58H80N10O17Pureza:98%Forma y color:SolidPeso molecular:1189.31Thevetiaflavone
CAS:<p>Thevetiaflavone, a natural flavonoid from W. indica, blocks LDH leakage, boosting cell survival.</p>Fórmula:C16H12O5Pureza:98%Forma y color:SolidPeso molecular:284.26BKM1644
CAS:<p>BKM1644 is an effective inhibition of the proliferation of metastatic, castration-resistant PCa (mCRPC) cells.</p>Fórmula:C34H37Cl2F5N2O9P2Pureza:98%Forma y color:SolidPeso molecular:845.51(Iso)-Z-VAD(OMe)-FMK
CAS:<p>(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor UCHL1.</p>Fórmula:C22H30FN3O7Pureza:97.10%Forma y color:SoildPeso molecular:467.49Ara-SH
<p>Ara-SH, a derivative of Cytarabine with a mercaptopropionic acid substitution, serves as the initiator for the self-assembly of a smart, co-loaded Cytarabine</p>Fórmula:C12H17N3O6SPureza:98%Forma y color:SolidPeso molecular:331.34Human membrane-bound PD-L1 polypeptide
CAS:<p>Human membrane-bound PD-L1 polypeptide serves as an antigen for inducing the production of PD-L1 antibodies [1].</p>Fórmula:C85H140N26O36SPureza:98%Forma y color:SolidPeso molecular:2134.24Waltonitone
CAS:<p>Waltonitone is a natural ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill.</p>Fórmula:C30H48O2Pureza:98%Forma y color:SolidPeso molecular:440.7Sodium propionate
CAS:Sodium propionate (Propionic acid sodium salt) has potential anti-inflammatory and anti-apoptotic activities, inhibiting certain signaling pathways.Fórmula:C3H5NaO2Forma y color:SoildPeso molecular:96.06Silicon naphthalocyanine dichloride
CAS:<p>Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. This compound is employed in photodynamic therapy to inhibit cancer by effectively absorbing specific wavelengths of light, thereby generating oxygen radicals that aid in the destruction of cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride demonstrates promising prospects for medical applications.</p>Fórmula:C48H24Cl2N8SiForma y color:SolidPeso molecular:811.75Pim-1 kinase inhibitor 4
Pim-1 kinase inhibitor 4 is a potent Pim-1 kinase inhibitor with an IC50 value of 17.01 nM.Pim-1 kinase inhibitor 4 also possesses antioxidant activity andFórmula:C19H12ClN3OPureza:97.37%Forma y color:SolidPeso molecular:333.77
