Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(125 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(125 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(92 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5600 productos de "Apoptosis"
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Nofazinlimab
CAS:<p>Nofazinlimab (CS1003) is a human anti-PD-1 IgG4 monoclonal antibody for the study of unresectable hepatocellular carcinoma (uHCC).</p>Pureza:98.6% (SDS-PAGE); 99.7% (SEC-HPLC) - 98.6% (SDS-PAGE); 99.7% (SEC-HPLC)Forma y color:LiquidLatikafusp
CAS:<p>Latikafusp (AMG 256) is a fusion protein that is a PD-1 blocker and IL-21R agonist with antitumor activity.</p>Pureza:97.1% (SDS-PAGE); 97.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.4% (SEC-HPLC)Forma y color:LiquidPacmilimab
CAS:<p>Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.</p>Pureza:98.8% (SDS-PAGE); 96.3% (SEC-HPLC) - 98.8% (SDS-PAGE); 96.3% (SEC-HPLC)Forma y color:LiquidAcrixolimab
CAS:<p>Acrixolimab is a humanized IgG4-κ monoclonal antibody that selectively targets PD-1 [1] [2].</p>Pureza:98%Forma y color:LiquidProlgolimab
CAS:<p>Prolgolimab (BCD-100) is an anti-PD-1 antibody used in melanoma research.</p>Pureza:>95%Forma y color:LiquidPoly (I:C):Kanamycin (1:1)
<p>Poly (I:C):Kanamycin (1:1) is an equimolar mixture of Poly(I:C) and kanamycin. TLR3 agonist commonly used as a vaccine adjuvant; enhanced Poly(I:C) stability.</p>Forma y color:SolidDanburstotug
CAS:<p>Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 (PDL1, B7 homologue 1, B7H1).</p>Pureza:98%Forma y color:Liquid4-Nitro-3-cresol
CAS:<p>4-Nitro-3-cresol exhibits ciliate toxicity against Tetrahymena pyriformis and is widely used in biochemical experiments and drug synthesis research.</p>Fórmula:C7H7NO3Pureza:99.87%Forma y color:Beige PowderPeso molecular:153.14WF 10129
CAS:<p>WF 10129 is a new angiotensin converting enzyme inhibitor generated by a fungus, Doratomyces putredinis.</p>Fórmula:C20H28N2O8Pureza:98%Forma y color:SolidPeso molecular:424.45Pro-GA
CAS:<p>Pro-GA is a cell-permeable γ-glutamylcyclotransferase (γ-GGCT) inhibitor that inhibit proliferation in multiple bladder cancer cell lines. antitumour.</p>Fórmula:C12H19NO7Forma y color:SolidPeso molecular:289.28Claturafenib
CAS:<p>Claturafenib is a brain-permeable, selective, all-mutant BRAF inhibitor.PF-07799933 has shown antitumor activity, used in combination with MEK inhibitors.</p>Fórmula:C18H15Cl2F2N5O3SPureza:98.68% - 99.85%Forma y color:SolidPeso molecular:490.31Solanidine
CAS:<p>Solanidine is a cholestane alkaloid isolated from potato species with antitumor effects. Solanidine inhibits proliferation.</p>Fórmula:C27H43NOPureza:96.83%Forma y color:SolidPeso molecular:397.64FOXJ1 agonist 1
<p>FOXJ1 agonist 1 (compound 16c), an orally effective small molecule, effectively enhances FOXJ1 expression and acts on multiciliated cells (MCC) in the mammalian airway system to prevent chronic obstructive pulmonary disease (COPD). Foxj1-IN-1 induces motile cilia production in the respiratory system of both zebrafish and mammals and inhibits elastase-induced COPD in mouse models. Additionally, Foxj1-IN-1 demonstrates good liver microsomal stability and favorable in vivo pharmacokinetic (PK) curves and area under the curve (AUC). It exhibits negligible inhibition of CYP and hERG and lacks significant cytotoxicity.</p>Fórmula:C24H27N5O3Forma y color:SolidPeso molecular:433.5Amorfrutin A
CAS:<p>Amorfrutin A is a useful organic compound for research related to life sciences. The catalog number is T124190 and the CAS number is 80489-90-3.</p>Fórmula:C21H24O4Forma y color:SolidPeso molecular:340.419BKM1644
CAS:<p>BKM1644 is an effective inhibition of the proliferation of metastatic, castration-resistant PCa (mCRPC) cells.</p>Fórmula:C34H37Cl2F5N2O9P2Pureza:98%Forma y color:SolidPeso molecular:845.51Isomahanine
<p>Isomahanine is a useful organic compound for research related to life sciences and the catalog number is T125848.</p>Fórmula:C23H25NO2Forma y color:SolidPeso molecular:347.458Apoptosis inducer 29
Apoptosis Inducer 29 (compound Y9) demonstrates anticancer efficacy in non-small cell lung cancer by inducing lysosomal dysfunction and apoptosis, and exhibits superior performance to Gboixn both in vitro and in vivo.Fórmula:C33H46ClN3O3Forma y color:SolidPeso molecular:568.192-Chloronaphthalene
CAS:<p>2-Chloronaphthalene is an organochlorine chemical compound and is a chlorinated derivative of naphthalene. The compound is an isomer for 1-chloronaphthalene.</p>Fórmula:C10H7ClPureza:98%Forma y color:SolidPeso molecular:162.62Sodium propionate
CAS:<p>Sodium propionate (Propionic acid sodium salt) has potential anti-inflammatory and anti-apoptotic activities, inhibiting certain signaling pathways.</p>Fórmula:C3H5NaO2Forma y color:SoildPeso molecular:96.06Silicon naphthalocyanine dichloride
CAS:<p>Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. This compound is employed in photodynamic therapy to inhibit cancer by effectively absorbing specific wavelengths of light, thereby generating oxygen radicals that aid in the destruction of cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride demonstrates promising prospects for medical applications.</p>Fórmula:C48H24Cl2N8SiForma y color:SolidPeso molecular:811.75MG-C-30
CAS:<p>MG-C-30 is an orally active CD27 agonist with an EC50 of 0.84 μM. It activates co-stimulatory signaling in NK cells and T cells, thereby enhancing the immune response. In the EG7-OVA mouse model, MG-C-30 demonstrates antitumor activity.</p>Fórmula:C24H26N4O3SForma y color:SolidPeso molecular:450.55Lambertianic acid
CAS:<p>Lambertianic acid is a bioactive chemical that has anti-allergic and antibacterial effects.</p>Fórmula:C20H28O3Pureza:98%Forma y color:SolidPeso molecular:316.441Fludioxonil
CAS:<p>Fludioxonil (CGA 173506), a phenylpyrrole fungicide, inhibits the growth of B. cinerea from strawberry and blackberry crops.</p>Fórmula:C12H6F2N2O2Pureza:99.971%Forma y color:SolidPeso molecular:248.18Aspochalasin D
CAS:<p>Aspochalasin D, isolated from A. microcysticus, shows antibacterial properties and cytotoxicity affecting Ba/F3-V12 cells, with IC50s of 0.49 and 1.9 μg/ml.</p>Fórmula:C24H35NO4Forma y color:SolidPeso molecular:401.54N-Acetylpsychosine
CAS:<p>N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties.</p>Fórmula:C26H49NO8Forma y color:SolidPeso molecular:503.67YJ1206
CAS:<p>YJ1206 is a highly potent and selective CDK12/13 PROTAC degrader oral, DNA damage and cell-cycle arrest,and inhibits the proliferation of prostate cancer cells.</p>Fórmula:C49H52FN11O5Pureza:97.14%Forma y color:SolidPeso molecular:894.01SC-2001
CAS:<p>SC-2001 inhibits MCL-1 and STAT3, enhances SHP-1, induces apoptosis in breast cancer, and counters STAT3-driven sorafenib resistance in liver cancer.</p>Fórmula:C18H14BrN3OPureza:98%Forma y color:SolidPeso molecular:368.23Linearol
CAS:<p>Linearol: diterpene from Sideritis L. with antioxidant, anti-inflammatory, anti-apoptotic effects.</p>Fórmula:C22H34O4Pureza:98%Forma y color:SolidPeso molecular:362.50spisulosine
CAS:<p>spisulosine is a natural product for research related to life sciences. The catalog number is T9664 and the CAS number is 196497-48-0.</p>Fórmula:C18H39NOForma y color:SolidPeso molecular:285.5161-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
CAS:<p>Phospholipid with stearic acid and 15(S)-HpETE boosts ferroptosis in MEFs upon GPX4 inhibition.</p>Fórmula:C43H78NO10PForma y color:SolidPeso molecular:800.068Albicanol
CAS:<p>Albicanol is a biochemical.</p>Fórmula:C15H26OForma y color:SolidPeso molecular:222.372Ceftiofur hydrochloride
CAS:<p>Ceftiofur hydrochloride (U-67279A) is a stable, broad-spectrum 3rd-gen cephalosporin with antibacterial properties.</p>Fórmula:C19H17N5O7S3·HClPureza:99.51%Forma y color:Off-White SolidPeso molecular:560.02NQO2-IN-1
CAS:<p>NQO2-IN-1, a resveratrol analog, is a potent NQO2 inhibito,antitumor,generation of ROS and up-regulation of DR5 (death receptor 5) to promote apoptosis.</p>Fórmula:C18H18N2O3Pureza:99.83%Forma y color:SoildPeso molecular:310.35Verproside
CAS:<p>Verproside is a useful organic compound for research related to life sciences. The catalog number is T124745 and the CAS number is 50932-20-2.</p>Fórmula:C22H26O13Forma y color:SolidPeso molecular:498.437RET-IN-28
CAS:<p>RET-IN-28 (Compound 16) is an inhibitor of RET (a transmembrane receptor tyrosine kinase). It specifically inhibits the activity of a mutant RET enzyme (RET-V804M) and is utilized in cancer research.</p>Fórmula:C26H29N9Forma y color:SolidPeso molecular:467.57(E/Z)-10-Hydroxy-2-decenoic acid
CAS:<p>(E/Z)-10-Hydroxy-2-decenoic acid is a useful organic compound for research related to life sciences.</p>Fórmula:C10H18O3Forma y color:SolidPeso molecular:186.251Streptonigrin
CAS:<p>Streptonigrin, from Streptomyces flocculus, has anti-tumor and anti-bacterial properties, inhibiting PAD1-4.</p>Fórmula:C25H22N4O8Pureza:98%Forma y color:SolidPeso molecular:506.46Topoisomerase I/II inhibitor 6
<p>TopoisomeraseI/II inhibitor 6 (compound 3i) acts as an effective inhibitor of topoisomerase I and II, with IC50 values of 4.77 µM and 15 µM, respectively. Additionally, it exhibits antiproliferative activity against the human melanoma cell line LOX IMVI, demonstrating IC50 values of 26.7 µM and 25.4 µM.</p>Fórmula:C31H28F2N4O6SForma y color:SolidPeso molecular:622.64Azadirone
CAS:<p>Azadirone, a limonoid, sensitizes cancer cells to TRAIL by modulating DR4/DR5, survival, and apoptotic proteins.</p>Fórmula:C9H15N3O5Forma y color:SolidPeso molecular:245.23Resolvin D2 n-3 DPA
CAS:<p>RvD2 n-3 DPA is an SPM made from docosapentaenoic acid in human leukocytes, inhibiting neutrophil chemotaxis and adhesion.</p>Fórmula:C22H34O5Forma y color:SolidPeso molecular:378.509HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Fórmula:C35H43Cl2F2N5O4Forma y color:SolidPeso molecular:706.65Verdinexor
CAS:<p>Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.</p>Fórmula:C18H12F6N6OPureza:98% - 99.68%Forma y color:SolidPeso molecular:442.32Vonlerolizumab
CAS:<p>Vonlerolizumab (MOXR 0916) is a humanized IgG OX40 agonist monoclonal antibody with potential in cancer and immune disease research.</p>Pureza:SDS-PAGE:97.3%;SEC-HPLC:99.4%Forma y color:LiquidPeso molecular:145.25 kDaRozanolixizumab
CAS:<p>Rozanolixizumab (RYSTIGGO) is a humanized IgG4 monoclonal antibody that targets FcRn in newborns for autoimmune research.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:95.9%Forma y color:LiquidPeso molecular:145.19 kDaConophylline
CAS:<p>Conophylline, an alkaloid from Ervatamia microphylla, induces pancreatic cell differentiation and apoptosis, and suppresses HSC.</p>Fórmula:C44H50N4O10Pureza:98%Forma y color:SolidPeso molecular:794.89(R)-JAK2/STAT3-IN-10a
CAS:<p>(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a structural domain inhibitor of GP130 D1 with antitumor activity.</p>Fórmula:C34H35BrF3N5O2Pureza:97.99%Forma y color:SoildPeso molecular:682.57Taltirelin acetate
CAS:<p>Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an</p>Fórmula:C19H27N7O7Pureza:99.21%Forma y color:SolidPeso molecular:465.46Ferroptosis-IN-14
<p>Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.</p>Forma y color:Odour SolidKB03-SLF
CAS:<p>KB03-SLF is a protease with the capability to target specific proteins and regulate intracellular protein levels by inducing protein degradation. This mechanism renders KB03-SLF potentially valuable in the suppression of related diseases.</p>Fórmula:C50H63ClF3N5O12Forma y color:SolidPeso molecular:1018.51WKYMVM
CAS:<p>WKYMVM is a N-formyl peptide receptor (FPR1) agonist.</p>Fórmula:C41H61N9O7S2Pureza:98%Forma y color:SolidPeso molecular:856.11
