Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(23 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5618 productos de "Apoptosis"
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Rosmarinic acid
CAS:<p>Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities.</p>Fórmula:C18H16O8Pureza:98.88% - 99.73%Forma y color:Brown Fine PowderPeso molecular:360.31NSC59984
CAS:<p>NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.</p>Fórmula:C12H15N3O4Pureza:99.33% - 99.59%Forma y color:SolidPeso molecular:265.27BAY 61-3606
CAS:<p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>Fórmula:C20H18N6O3Pureza:98.72%Forma y color:SolidPeso molecular:390.4Chloropyramine
CAS:<p>Chloropyramine: H1 antagonist for allergies like conjunctivitis, asthma; has anti-breast cancer properties.</p>Fórmula:C16H20ClN3Forma y color:SolidPeso molecular:289.8SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Forma y color:Pale YellowPeso molecular:331.3420(R)-Ginsenoside Rh2
CAS:<p>20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.</p>Fórmula:C36H62O8Pureza:99.58%Forma y color:SolidPeso molecular:622.87Amentoflavone
CAS:<p>Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.</p>Fórmula:C30H18O10Pureza:98.21% - 99.22%Forma y color:Odourless Whitish SolidPeso molecular:538.46WYC-209
CAS:<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Fórmula:C20H20N2O3SPureza:99.77%Forma y color:SolidPeso molecular:368.452-tert-Butyl-1,4-benzoquinone
CAS:<p>TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.</p>Fórmula:C10H12O2Pureza:97.19%Forma y color:SolidPeso molecular:164.2Methoxyamine HCl
CAS:<p>Methoxyamine HCl targets DNA repair sites, potentially increasing DNA breaks and enhancing alkylating agents' anti-cancer effects.</p>Fórmula:CH6ClNOPureza:≥98%Forma y color:SolidPeso molecular:83.51KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Fórmula:C20H20N4OPureza:98.43% - 99.69%Forma y color:SolidPeso molecular:332.4SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Forma y color:SolidPeso molecular:352.47Nafamostat mesylate
CAS:<p>Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis</p>Fórmula:C19H17N5O2·2CH4O3SPureza:97.36% - 99.76%Forma y color:Tan To Pale Orange SolidPeso molecular:539.58Benidipine
CAS:<p>Benidipine: potent oral calcium blocker, boosts nitric oxide synthase, enhances coronary flow, protects heart cells post-ischemia.</p>Fórmula:C28H31N3O6Forma y color:SolidPeso molecular:505.56Etidronic acid
CAS:<p>Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.</p>Fórmula:C2H8O7P2Pureza:99.93% - ≥95%Forma y color:Liquid SyrupPeso molecular:206.03TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H31N3O5Pureza:98% - 99.25%Forma y color:SolidPeso molecular:465.54Difurazon hydrochloride
CAS:<p>Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.</p>Fórmula:C14H13ClN6O6Pureza:98.51%Forma y color:SolidPeso molecular:396.74dBET6
CAS:<p>dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.</p>Fórmula:C42H45ClN8O7SPureza:97.57% - 99.12%Forma y color:SolidPeso molecular:841.37Thalidomide-NH-C4-NH-Boc
CAS:<p>Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.</p>Fórmula:C22H28N4O6Pureza:98.87%Forma y color:SolidPeso molecular:444.48Thalidomide-4-OH
CAS:<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Fórmula:C13H10N2O5Pureza:99.59%Forma y color:SolidPeso molecular:274.23Dinaciclib
CAS:<p>Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).</p>Fórmula:C21H28N6O2Pureza:98.21% - 99.75%Forma y color:SolidPeso molecular:396.49GSK778 hydrochloride
CAS:GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.Fórmula:C30H34ClN5O3Pureza:97.26% - 98.35%Forma y color:SolidPeso molecular:548.08Astragalin
CAS:<p>Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.</p>Fórmula:C21H20O11Pureza:98.8% - ≥95%Forma y color:SolidPeso molecular:448.38PRLX-93936
CAS:<p>PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.</p>Fórmula:C21H24N4O2Forma y color:SolidPeso molecular:364.44Desciclovir
CAS:<p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>Fórmula:C8H11N5O2Pureza:99.54%Forma y color:SolidPeso molecular:209.21Phellamurin
CAS:<p>Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.</p>Fórmula:C26H30O11Pureza:97.91%Forma y color:SolidPeso molecular:518.51PNU-74654
CAS:<p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>Fórmula:C19H16N2O3Pureza:97.27%Forma y color:SolidPeso molecular:320.34Pracinostat
CAS:<p>Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral</p>Fórmula:C20H30N4O2Pureza:99.15% - 99.67%Forma y color:SolidPeso molecular:358.482-Hydroxychalcone
CAS:<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Fórmula:C15H12O2Pureza:99.6%Forma y color:SolidPeso molecular:224.25UC2288
CAS:<p>UC2288, a Sorafenib-based p21 attenuator, reduces p21 levels without affecting its stability.</p>Fórmula:C20H18ClF6N3O2Pureza:99.75%Forma y color:SolidPeso molecular:481.82Brassinolide
CAS:<p>Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.</p>Fórmula:C28H48O6Pureza:98% - 99.189%Forma y color:Off-White SolidPeso molecular:480.682-HBA
CAS:<p>2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.</p>Fórmula:C17H14O3Pureza:99.76%Forma y color:SolidPeso molecular:266.29GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Fórmula:C43H46F3N7O7SPureza:98.78% - >99.99%Forma y color:SolidPeso molecular:861.93Ginkgetin
CAS:<p>Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.</p>Fórmula:C32H22O10Pureza:98.63% - 99.94%Forma y color:SolidPeso molecular:566.51Indirubin
CAS:<p>Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.</p>Fórmula:C16H10N2O2Pureza:97.21% - 99.74%Forma y color:Reddish-Violet PowderPeso molecular:262.26Liproxstatin-1 hydrochloride
CAS:<p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>Fórmula:C19H22Cl2N4Forma y color:SolidPeso molecular:377.31Valproic Acid
CAS:<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Fórmula:C8H16O2Pureza:97.78% - 99%Forma y color:Colourless To Pale Yellow Liquid ViscousPeso molecular:144.21MK-2206
CAS:<p>MK-2206: selective Akt inhibitor, oral, targets Akt1, Akt2, Akt3; effective in breast cancer, PIK3CA mutants, PTEN-deficient cells.</p>Fórmula:C25H22ClN5OForma y color:SolidPeso molecular:443.94GSK1059615
CAS:<p>GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.</p>Fórmula:C18H11N3O2SPureza:99.3% - ≥95%Forma y color:SolidPeso molecular:333.36Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Fórmula:C22H22O4Pureza:99.73%Forma y color:SolidPeso molecular:350.41Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Fórmula:C25H22N4O4Pureza:99.27%Forma y color:Orange To Red SolidPeso molecular:442.47Milademetan free base
CAS:<p>Milademetan (DS-3032b) is a potent MDM2 inhibitor, potentially blocking cancer growth by targeting p53 protein.</p>Fórmula:C37H42Cl2FN5O7SPureza:98%Forma y color:SolidPeso molecular:790.73STF-118804
CAS:<p>STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.</p>Fórmula:C25H23N3O4SPureza:98.66%Forma y color:SolidPeso molecular:461.53Methoxychlor
CAS:<p>Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.</p>Fórmula:C16H15Cl3O2Pureza:98.82% - ≥95%Forma y color:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfPeso molecular:345.65[6]-Gingerol
CAS:<p>[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.</p>Fórmula:C17H26O4Pureza:98% - 99.66%Forma y color:Light Yellow OilinessPeso molecular:294.39DIM-C-pPhCO2Me
CAS:<p>DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.</p>Fórmula:C25H20N2O2Pureza:99.55% - 99.86%Forma y color:SolidPeso molecular:380.44Epoxiconazole
CAS:<p>Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.</p>Fórmula:C17H13ClFN3OPureza:98.57%Forma y color:Solid PowderPeso molecular:329.76SKI II
CAS:SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.Fórmula:C15H11ClN2OSPureza:99.34% - 99.93%Forma y color:SolidPeso molecular:302.78Diffractaic Acid
CAS:<p>Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.</p>Fórmula:C20H22O7Pureza:99.81% - 99.87%Forma y color:SolidPeso molecular:374.38
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