Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(125 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(125 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(92 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5600 productos de "Apoptosis"
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DAPT
CAS:<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Forma y color:White SolidPeso molecular:432.46Didymin
CAS:<p>Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.</p>Fórmula:C28H34O14Pureza:99.12% - 99.87%Forma y color:Faintly Beige PowderPeso molecular:594.56AZ960
CAS:<p>AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).</p>Fórmula:C18H16F2N6Pureza:96.02% - 98.51%Forma y color:SolidPeso molecular:354.36Sulforaphane
CAS:<p>Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.</p>Fórmula:C6H11NOS2Pureza:95% - 99.79%Forma y color:Light Yellow LiquidPeso molecular:177.29Fimepinostat
CAS:<p>Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.</p>Fórmula:C23H24N8O4SPureza:98.27% - 99.87%Forma y color:SolidPeso molecular:508.55Ipatasertib
CAS:<p>Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.</p>Fórmula:C24H32ClN5O2Pureza:98.28% - 99.21%Forma y color:SolidPeso molecular:458Almorexant
CAS:<p>Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.</p>Fórmula:C29H31F3N2O3Pureza:97.75% - 98.02%Forma y color:SolidPeso molecular:512.56TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Forma y color:SolidPeso molecular:428.82Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Fórmula:C33H25F6N3O3Pureza:99.75%Forma y color:SolidPeso molecular:625.56Nutlin-3a
CAS:<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Forma y color:SolidPeso molecular:581.49Gemcitabine hydrochloride
CAS:<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Forma y color:White Crystalline Granular OdorlessPeso molecular:299.66EB-3D
CAS:<p>EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.</p>Fórmula:C30H36Br2N4O2Pureza:99.48%Forma y color:SolidPeso molecular:644.4Pogostone
CAS:<p>Pogostone: anti-bacterial/fungal, blocks T-cells, modulates cytokines, protects against gastric ulcers, boosts antioxidants/PGE2/NP-SH.</p>Fórmula:C12H16O4Pureza:98.46% - 99.03%Forma y color:SolidPeso molecular:224.25Bilobalide
CAS:<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Fórmula:C15H18O8Pureza:98.81% - 99.92%Forma y color:White SolidPeso molecular:326.3CID5721353
CAS:<p>CID5721353 disrupts BCL6/corepressor complexes, binds critical BTB groove site in vitro/vivo.</p>Fórmula:C15H9BrN2O6S2Pureza:98.90%Forma y color:SolidPeso molecular:457.28Schisandrin C
CAS:<p>Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.</p>Fórmula:C22H24O6Pureza:99.44% - 99.56%Forma y color:SolidPeso molecular:384.42FTI-277 hydrochloride
CAS:<p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>Fórmula:C22H30ClN3O3S2Pureza:97.57% - 97.61%Forma y color:SolidPeso molecular:484.07CCG-1423
CAS:<p>CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.</p>Fórmula:C18H13ClF6N2O3Pureza:99.80%Forma y color:SolidPeso molecular:454.75NQDI-1
CAS:<p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>Fórmula:C19H13NO4Pureza:97.1% - 98.10%Forma y color:SolidPeso molecular:319.313-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Forma y color:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08Lupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Fórmula:C20H18O5Pureza:98.92%Forma y color:SolidPeso molecular:338.35BTdCPU
CAS:<p>BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.</p>Fórmula:C13H8Cl2N4OSPureza:98.94% - 99.59%Forma y color:SolidPeso molecular:339.2NVP-CGM097
CAS:<p>NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).</p>Fórmula:C38H47ClN4O4Pureza:98.77%Forma y color:SolidPeso molecular:659.26MK-4101
CAS:<p>MK-4101 inhibits Hedgehog pathway, causing apoptosis and reduced proliferation in cancer cells.</p>Fórmula:C24H24F5N5OPureza:98.2% - 99.13%Forma y color:SolidPeso molecular:493.47Tomivosertib HCl
CAS:<p>Tomivosertib (eFT508) is a MNK1/2 inhibitor that blocks eIF4E phosphorylation, hindering tumor growth and immune signaling.</p>Fórmula:C17H21ClN6O2Forma y color:SolidPeso molecular:376.8451400W dihydrochloride
CAS:<p>1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).</p>Fórmula:C10H17Cl2N3Pureza:98% - 99.94%Forma y color:SolidPeso molecular:250.17α-Lipoic Acid sodium
CAS:<p>α-Lipoic Acid (Thioctic acid) sodium, an essential cofactor for mitochondrial enzyme complexes, serves as an antioxidant.</p>Fórmula:C8H13NaO2S2Forma y color:SolidPeso molecular:228.31Aloperine
CAS:<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Fórmula:C15H24N2Pureza:98% - 99.88%Forma y color:Yellow Crystalline PowderPeso molecular:232.36WP1066
CAS:<p>WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.</p>Fórmula:C17H14BrN3OPureza:98.92% - 99.73%Forma y color:SolidPeso molecular:356.22Emricasan
CAS:<p>Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.</p>Fórmula:C26H27F4N3O7Pureza:98.13% - 99%Forma y color:SolidPeso molecular:569.5SM-164
CAS:<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Fórmula:C62H84N14O6Pureza:98.53% - 99.92%Forma y color:SolidPeso molecular:1121.42HJC0152 hydrochloride
CAS:<p>HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.</p>Fórmula:C15H14Cl3N3O4Pureza:99.01% - 99.06%Forma y color:SolidPeso molecular:406.64EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Forma y color:SolidPeso molecular:413.4IITZ-01
CAS:<p>IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)</p>Fórmula:C26H23FN8OPureza:99.31%Forma y color:SolidPeso molecular:482.51Selumetinib
CAS:<p>Selumetinib (AZD6244) is a selectivity and non-ATP-competitive MEK1/2 inhibitor. Selumetinib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C17H15BrClFN4O3Pureza:98.1% - 99.90%Forma y color:White Or Pale White SolidPeso molecular:457.68Solamargine
CAS:<p>Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.</p>Fórmula:C45H73NO15Pureza:99.17% - 99.96%Forma y color:SolidPeso molecular:868.06DPN
CAS:<p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>Fórmula:C15H13NO2Pureza:99.01%Forma y color:Off-White SolidPeso molecular:239.27Baicalein monohydrate
CAS:<p>Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.</p>Fórmula:C15H12O6Forma y color:SolidPeso molecular:288.25AR42
CAS:<p>AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).</p>Fórmula:C18H20N2O3Pureza:98.46% - 98.96%Forma y color:SolidPeso molecular:312.36RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Fórmula:C23H21ClN2O5Pureza:98% - 99.96%Forma y color:SolidPeso molecular:440.88Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Forma y color:SolidPeso molecular:532.61Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Forma y color:SolidPeso molecular:432.4NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Fórmula:C27H34N4O5Pureza:99.59%Forma y color:SolidPeso molecular:494.58Ganoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Forma y color:SolidPeso molecular:514.65Prexasertib Mesylate Hydrate
CAS:<p>Prexasertib Mesylate Hydrate is a potent CHK1 inhibitor (IC50<1nM), also inhibits CHK2, RSK1, induces DNA breaks, apoptosis, and has anti-tumor effects.</p>Fórmula:C19H25N7O6SForma y color:SolidPeso molecular:479.51PEAQX
CAS:<p>PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).</p>Fórmula:C17H17BrN3O5PPureza:98% - 99.9%Forma y color:SolidPeso molecular:454.21α-Mangostin
CAS:<p>alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.</p>Fórmula:C24H26O6Pureza:98.22% - 99.49%Forma y color:Yellow PowderPeso molecular:410.46JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Fórmula:C15H12F2N6O3SPureza:99.1% - 99.85%Forma y color:SolidPeso molecular:394.36Pembrolizumab
CAS:<p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>Pureza:95% - 99.70%Forma y color:LiquidPeso molecular:149 kDa
