Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(125 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(125 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(92 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5600 productos de "Apoptosis"
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Laquinimod sodium
CAS:<p>Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.</p>Fórmula:C19H16ClN2NaO3Forma y color:SolidPeso molecular:378.79Copanlisib
CAS:<p>Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.</p>Fórmula:C23H28N8O4Pureza:99% - 99.88%Forma y color:SolidPeso molecular:480.52Sodium benzoate
CAS:<p>Sodium benzoate (Benzoic acid sodium salt) is a D-Amino Acid Oxidase Inhibitor.Sodium Benzoate is a Food Preservative.</p>Fórmula:C7H5NaO2Pureza:99.72%Forma y color:White Solid CrystallinePeso molecular:144.10Valproic Acid
CAS:<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Fórmula:C8H16O2Pureza:97.78% - 99%Forma y color:Colourless To Pale Yellow Liquid ViscousPeso molecular:144.21Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Fórmula:C20H18O11Pureza:97.02% - 99.94%Forma y color:White PowderPeso molecular:434.35Enzastaurin
CAS:<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Fórmula:C32H29N5O2Pureza:98% - >99.99%Forma y color:SolidPeso molecular:515.6Afimetoran
CAS:<p>Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.</p>Fórmula:C26H32N6OPureza:99.81% - 99.94%Forma y color:SolidPeso molecular:444.57Notopterol
CAS:<p>1. Notopterol induces apoptosis and inhibits cell cycle-specific.</p>Fórmula:C21H22O5Pureza:97.57% - 99.82%Forma y color:SolidPeso molecular:354.4PRLX-93936
CAS:<p>PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.</p>Fórmula:C21H24N4O2Forma y color:SolidPeso molecular:364.44NPS-1034
CAS:<p>NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.</p>Fórmula:C31H23F2N5O3Pureza:98.48%Forma y color:SolidPeso molecular:551.54Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Fórmula:C15H17ClFNO4SPureza:99.31% - >99.99%Forma y color:SolidPeso molecular:361.82PNU-74654
CAS:<p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>Fórmula:C19H16N2O3Pureza:97.27%Forma y color:SolidPeso molecular:320.34Thalidomide-PEG4-Propargyl
CAS:<p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>Fórmula:C24H28N2O9Pureza:97.46%Forma y color:SolidPeso molecular:488.49Tiplaxtinin
CAS:<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Fórmula:C24H16F3NO4Pureza:99.16% - 99.93%Forma y color:SolidPeso molecular:439.38Flavokawain C
CAS:<p>Flavokawain C: natural chalcone from Kava with potential as a colon cancer drug.</p>Fórmula:C17H16O5Pureza:99.94% - ≥95%Forma y color:SolidPeso molecular:300.31Fluazinam
CAS:<p>Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.</p>Fórmula:C13H4Cl2F6N4O4Pureza:98% - 99.7%Forma y color:Light Yellow CrystalsPeso molecular:465.09MCB-613
CAS:<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Fórmula:C20H20N2OPureza:98.17% - 99.754%Forma y color:SolidPeso molecular:304.39SKLB-163
CAS:<p>SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.</p>Fórmula:C18H16ClN3O2S2Pureza:99.23%Forma y color:SolidPeso molecular:405.92Mitoxantrone diacetate
CAS:<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Fórmula:C26H36N4O10Forma y color:SolidPeso molecular:564.592(R)-(-)-Gossypol acetic acid
CAS:<p>(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.</p>Fórmula:C30H30O8·C2H4O2Pureza:98.88% - 99.5%Forma y color:SolidPeso molecular:578.61Fedratinib
CAS:Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Fórmula:C27H36N6O3SPureza:97.31% - 99.96%Forma y color:SolidPeso molecular:524.68PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Forma y color:SolidPeso molecular:237.32VR23
CAS:<p>VR23: Potent proteasome inhibitor; IC50: 1 nM trypsin, 50-100 nM chymotrypsin, 3 μM caspase-like.</p>Fórmula:C19H16ClN5O6SPureza:98.99% - 99.22%Forma y color:SolidPeso molecular:477.88Dimethyl malonate
CAS:<p>Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.</p>Fórmula:C5H8O4Pureza:≥95%Forma y color:LiquidPeso molecular:132.11Itanapraced
CAS:<p>Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).</p>Fórmula:C16H11Cl2FO2Pureza:98% - 99.79%Forma y color:SolidPeso molecular:325.16Siremadlin
CAS:<p>Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.</p>Fórmula:C26H24Cl2N6O4Pureza:99.30% - 99.76%Forma y color:SolidPeso molecular:555.41Terrestrosin D
CAS:<p>Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.</p>Fórmula:C50H80O23Pureza:99.92% - 99.96%Forma y color:SolidPeso molecular:1049.16SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Forma y color:Pale YellowPeso molecular:331.34Ganetespib
CAS:<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Fórmula:C20H20N4O3Pureza:98% - 99.95%Forma y color:SolidPeso molecular:364.4Meloxicam sodium
CAS:<p>Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].</p>Fórmula:C14H12N3NaO4S2Forma y color:SolidPeso molecular:373.38Rosmarinic acid
CAS:<p>Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities.</p>Fórmula:C18H16O8Pureza:98.88% - 99.73%Forma y color:Brown Fine PowderPeso molecular:360.31Atorvastatin hemicalcium salt
CAS:<p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>Fórmula:C33H34FN2O5CaPureza:99.27% - >99.99%Forma y color:White Crystalline PowderPeso molecular:577.67Aminopurvalanol A
CAS:<p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>Fórmula:C19H26ClN7OPureza:99.73%Forma y color:SolidPeso molecular:403.91Ulinastatin
CAS:<p>Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.</p>Fórmula:C13H16O3Pureza:98%Forma y color:SolidPeso molecular:220.10994Droxinostat
CAS:<p>Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3</p>Fórmula:C11H14ClNO3Pureza:99.83%Forma y color:SolidPeso molecular:243.69SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Forma y color:SolidPeso molecular:352.47Apomine
CAS:<p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>Fórmula:C28H52O7P2Pureza:>99.99%Forma y color:SolidPeso molecular:562.66Prexasertib
CAS:<p>Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!</p>Fórmula:C18H19N7O2Pureza:97.3% - 98.23%Forma y color:SolidPeso molecular:365.398-Bromo-cAMP sodium salt
CAS:<p>8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.</p>Fórmula:C10H10BrN5NaO6PPureza:98% - 99.94%Forma y color:Off-White PowderPeso molecular:430.08Caffeic Acid Phenethyl Ester
CAS:<p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>Fórmula:C17H16O4Pureza:99.18% - 99.35%Forma y color:Less Transparent Liquid Colorless Transparent LiquidPeso molecular:284.31TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Fórmula:C10H14O2Pureza:99.17% - 99.53%Forma y color:White Solid PowderPeso molecular:166.22C5 Lenalidomide
CAS:<p>C5 Lenalidomide is an chemical weith inconclusive biological activity.</p>Fórmula:C13H13N3O3Pureza:99.4%Forma y color:SolidPeso molecular:259.26Kinetin riboside
CAS:<p>Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)</p>Fórmula:C15H17N5O5Pureza:98.17%Forma y color:White SolidPeso molecular:347.33Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Fórmula:C17H16O4Pureza:99.87% - ≥95%Forma y color:SolidPeso molecular:284.31Dacomitinib
CAS:<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Forma y color:SolidPeso molecular:469.94Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Fórmula:C22H22O4Pureza:99.73%Forma y color:SolidPeso molecular:350.41Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Fórmula:C36H62O8Pureza:99.20% - 99.76%Forma y color:White PowderPeso molecular:622.87Flupentixol dihydrochloride
CAS:<p>Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.</p>Fórmula:C23H27Cl2F3N2OSPureza:98.76% - >99.99%Forma y color:White Or Off-White SolidPeso molecular:507.43PR-619
CAS:<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Fórmula:C7H5N5S2Pureza:97.25% - >99.99%Forma y color:SolidPeso molecular:223.28
