Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(23 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5618 productos de "Apoptosis"
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IACS-010759
CAS:<p>IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.</p>Fórmula:C25H25F3N6O4SPureza:99.54% - 99.73%Forma y color:SolidPeso molecular:562.56TPCA-1
CAS:<p>TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases</p>Fórmula:C12H10FN3O2SPureza:95.03% - 97.86%Forma y color:SolidPeso molecular:279.29Oxysophoridine
CAS:Oxysophoridine protects against brain ischemia and heart damage through antioxidant, anti-apoptotic, and anti-inflammatory effects.Fórmula:C15H24N2O2Pureza:98.15% - >99.99%Forma y color:SolidPeso molecular:264.36Poziotinib
CAS:<p>Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).</p>Fórmula:C23H21Cl2FN4O3Pureza:98.69% - 99.78%Forma y color:SolidPeso molecular:491.34Kumatakenin
CAS:<p>Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.</p>Fórmula:C17H14O6Pureza:97.44% - 98.29%Forma y color:SolidPeso molecular:314.29BG45
CAS:<p>BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.</p>Fórmula:C11H10N4OPureza:99.77%Forma y color:SolidPeso molecular:214.22BRD3308
CAS:BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.Fórmula:C15H14FN3O2Pureza:97%Forma y color:SolidPeso molecular:287.29PS-1145
CAS:<p>PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.</p>Fórmula:C17H11ClN4OPureza:98.81% - >99.99%Forma y color:SolidPeso molecular:322.75Epieriocalyxin A
CAS:<p>Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.</p>Fórmula:C20H24O5Pureza:97.00%Forma y color:SolidPeso molecular:344.4Helichrysetin
CAS:<p>Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.</p>Fórmula:C16H14O5Pureza:96.32% - ≥95%Forma y color:SolidPeso molecular:286.28Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Forma y color:White SolidPeso molecular:562.7Navtemadlin
CAS:<p>Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM).Cost-effective and quality-assured.</p>Fórmula:C28H35Cl2NO5SPureza:95.55% - 99.08%Forma y color:SolidPeso molecular:568.55Paederosidic acid
CAS:<p>Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.</p>Fórmula:C18H24O12SPureza:98% - 99.56%Forma y color:SolidPeso molecular:464.445'-Methylthioadenosine
CAS:<p>5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.</p>Fórmula:C11H15N5O3SPureza:99.32% - 99.34%Forma y color:SolidPeso molecular:297.33(20S)-Protopanaxatriol
CAS:<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Fórmula:C30H52O4Pureza:95% - 99%Forma y color:SolidPeso molecular:476.73(Rac)-Idroxioleic acid
CAS:<p>(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.</p>Fórmula:C18H34O3Pureza:≥98%Forma y color:SolidPeso molecular:298.46K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Fórmula:C15H17ClIN3O3Pureza:97.16%Forma y color:SolidPeso molecular:449.67NVP-TAE 226
CAS:<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Fórmula:C23H25ClN6O3Pureza:98.07% - 98.78%Forma y color:SolidPeso molecular:468.94Mycophenolate Mofetil
CAS:<p>Mycophenolate Mofetil (TM-MMF), is an immunosuppressive agent, 2-morpholinoethyl ester of MPA, and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).</p>Fórmula:C23H31NO7Pureza:98.27% - 99.85%Forma y color:White To Off-White Crystalline PowderPeso molecular:433.49Sclareol
CAS:<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Fórmula:C20H36O2Pureza:99.58% - 99.97%Forma y color:White Fine PowderPeso molecular:308.5TW-37
CAS:<p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>Fórmula:C33H35NO6SPureza:97.06% - ≥95%Forma y color:SolidPeso molecular:573.7Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Fórmula:C25H22N4O4Pureza:99.27%Forma y color:Orange To Red SolidPeso molecular:442.47Ginkgetin
CAS:<p>Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.</p>Fórmula:C32H22O10Pureza:98.63% - 99.94%Forma y color:SolidPeso molecular:566.51TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07DD1
CAS:<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Fórmula:C16H14N2O3Pureza:99.57%Forma y color:SolidPeso molecular:282.29SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Forma y color:SolidPeso molecular:352.47Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Fórmula:C22H22O4Pureza:99.73%Forma y color:SolidPeso molecular:350.41Vanillyl Alcohol
CAS:<p>Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.</p>Fórmula:C8H10O3Pureza:97.02% - 98.42%Forma y color:Crystalline White To Off-White PowderPeso molecular:154.16Ixabepilone
CAS:Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor.Fórmula:C27H42N2O5SPureza:98% - 99.50%Forma y color:SolidPeso molecular:506.7Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Forma y color:Yellowish SolidPeso molecular:379.88NSC 15364
CAS:<p>NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.</p>Fórmula:C13H14N4OPureza:98.67%Forma y color:SolidPeso molecular:242.28Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Forma y color:Off-White PowderPeso molecular:466.53Deoxypodophyllotoxin
CAS:<p>Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.</p>Fórmula:C22H22O7Pureza:99.65% - 99.84%Forma y color:SolidPeso molecular:398.413-O-Methylgallic acid
CAS:<p>3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and</p>Fórmula:C8H8O5Pureza:99.56%Forma y color:SolidPeso molecular:184.15W-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Fórmula:C16H22Cl2N2O2SPureza:99.63%Forma y color:White Crystalline SolidPeso molecular:377.32Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Forma y color:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Clobenpropit dihydrobromide
CAS:<p>Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)</p>Fórmula:C14H19Br2ClN4SPureza:99.86%Forma y color:SolidPeso molecular:470.7Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Forma y color:SolidPeso molecular:384.27Otenaproxesul
CAS:Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.Fórmula:C21H19NO3SPureza:98.76% - 99.13%Forma y color:SolidPeso molecular:365.45iCRT3
CAS:<p>iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.</p>Fórmula:C23H26N2O2SPureza:98.32% - 98.47%Forma y color:SolidPeso molecular:394.53Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Fórmula:C32H48N4O8·HClPureza:99.94%Forma y color:SolidPeso molecular:653.21Ganoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Forma y color:SolidPeso molecular:514.65Pembrolizumab
CAS:<p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>Pureza:95% - 99.70%Forma y color:LiquidPeso molecular:149 kDaTorin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Forma y color:SolidPeso molecular:432.4IITZ-01
CAS:<p>IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)</p>Fórmula:C26H23FN8OPureza:99.31%Forma y color:SolidPeso molecular:482.513-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Forma y color:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08BTdCPU
CAS:<p>BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.</p>Fórmula:C13H8Cl2N4OSPureza:98.94% - 99.59%Forma y color:SolidPeso molecular:339.2Demethylzeylasteral
CAS:<p>Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities.</p>Fórmula:C29H36O6Pureza:98.74% - 99.82%Forma y color:SolidPeso molecular:480.59Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Fórmula:C50H71N13O12Pureza:95% - >99.99%Forma y color:SolidPeso molecular:1046.18Mancozeb
CAS:<p>Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.</p>Fórmula:C8H12MnN4S8ZnPureza:98%Forma y color:Grayish-Yellow PowderPeso molecular:541.08
