Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(1 productos)
- Caspasa(154 productos)
- FOXO1(2 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(23 productos)
- Serina / treonina quinasa(17 productos)
- Survivin(14 productos)
- TNF(91 productos)
- c-RET(61 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 6170 productos de "Apoptosis"
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EGFR-IN-45
EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.Fórmula:C28H23N7OForma y color:SolidPeso molecular:473.53CAR-2
CAS:CAR-2 is a BODIPY-based photosensitizer that induces ferroptosis in photodynamic therapy (PDT) by targeting the endoplasmic reticulum (ER) and lipid droplets (LD). It exhibits phototoxicity against breast cancer cells with an IC50 of 0.01-0.02 μM and demonstrates antitumor efficacy in a 4T1 xenograft mouse model.Fórmula:C27H23BF2I2N4O2Forma y color:SolidPeso molecular:738.114FLT3/TrKA-IN-1
FLT3/TrKA-IN-1: Potent dual kinase inhibitor for FLT3 & TrKA, promising for AML research.Fórmula:C28H30N4O2Forma y color:SolidPeso molecular:454.56Tubulin inhibitor 17
Compound 3b inhibits tubulin polymerization, IC50 12.38 µM, with anticancer properties and promotes cell apoptosis.Fórmula:C17H16N2OForma y color:SolidPeso molecular:264.32CK156
CAS:CK156 inhibits DAPK with high selectivity; IC50: 182 nM (DRAK1), 34 μM (CK2a1), 39 μM (CK2a2); key in autoimmune/inflammation research.Fórmula:C21H25N5O3Forma y color:SolidPeso molecular:395.45Akt/NF-κB/JNK-IN-1
Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxideFórmula:C22H22N2O6Forma y color:SolidPeso molecular:410.42KIRA9
KIRA9 inhibits IRE1 with a 4.8 μM IC50, blocking ER-stress-induced mRNA decay and apoptosis by fully binding IRE1's ATP site.Fórmula:C27H27F3N6O3SForma y color:SolidPeso molecular:572.6Bcl-2-IN-7
Bcl-2-IN-7 inhibits Bcl-2, encourages apoptosis in cancer cells, and has anti-tumor activity with various IC50 values.Fórmula:C24H22N4O5S2Forma y color:SolidPeso molecular:510.59Mcl-1 inhibitor 9
CAS:Mcl-1 Inhibitor 9 (Example 2) is a potent inhibitor of myeloid cell leukemia 1 (Mcl-1), demonstrating anti-tumor activity with an IC50 value of 0.21889 nM.Fórmula:C32H39ClN2O5SForma y color:SolidPeso molecular:599.18Bcl-2-IN-6
Bcl-2-IN-6 suppresses Bcl-2, upregulates p53/Bax/caspase-7, arrests cell cycle, and induces MCF-7 apoptosis; IC50s: MCF-7 20.91 μM, others <48 μM.Fórmula:C25H24N4O5S2Forma y color:SolidPeso molecular:524.61HDAC1-IN-5
HDAC1-IN-5 inhibits HDAC1 (IC50=15 nM) & HDAC6 (IC50=20 nM), promotes apoptosis, damages chromatin, and reduces tumor growth in mice.Fórmula:C20H21N3O2SForma y color:SolidPeso molecular:367.46PARP10/15-IN-2
CAS:PARP10/15-IN-2 (Compound 8h) blocks PARP10/15, has IC50s: 0.15μM/0.37μM, cell-permeable, prevents apoptosis.Fórmula:C15H11FN2O3Forma y color:SolidPeso molecular:286.26Bomedemstat hydrochloride
Bomedemstat (IMG-7289) hydrochloride, an oral LSD1 inhibitor, has anticancer properties, blocking cell growth and triggering apoptosis.Fórmula:C28H35ClFN7O2Forma y color:SolidPeso molecular:556.08PD-1/PD-L1-IN-16
PD-1/PD-L1-IN-16 is a potent inhibitor of PD-1/PD-L1 (IC50: 53.2 nM) and has shown research potential for tumour immunotherapy.Fórmula:C34H30N4O4Forma y color:SolidPeso molecular:558.63VEGFR-2-IN-14
VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.Fórmula:C24H23N3O3SForma y color:SolidPeso molecular:433.52Topoisomerase inhibitor 4
CAS:Topoisomerase inhibitor4 (compound 45) acts as an effective inhibitor of Topoisomerase1/2, arresting the cell cycle at the G2/M phase and inducing Apoptosis. This compound exhibits potent antitumor activity.Fórmula:C30H28F3IN4O3Forma y color:SolidPeso molecular:676.47Verrucarin A
CAS:Verrucarin A, a mycotoxin from Myrothecium verrucaria, inhibits protein synthesis, leukemia growth, and triggers apoptosis.Fórmula:C27H34O9Forma y color:SolidPeso molecular:502.55Topoisomerase I/II inhibitor 3
Topoisomerase I/II inhibitor 3 suppresses cell growth and induces apoptosis in liver cancer by blocking PI3K/Akt/mTOR.Fórmula:C24H24N2O4Forma y color:SolidPeso molecular:404.46PD-1/PD-L1-IN-30
CAS:PD-1/PD-L1-IN-30: Cancer research inhibitor with 0.018 μM IC50.Fórmula:C29H28F3NO5Forma y color:SolidPeso molecular:527.53Antitumor agent-78
Antitumor agent-78 blocks GPx-4, raises COX2, triggers apoptosis, halts EMT, and stifles cancer cell growth and migration.Forma y color:Soild
