Receptor de andrógenos
El receptor de andrógenos (AR) es un receptor hormonal nuclear que se activa al unirse a andrógenos, como la testosterona y la dihidrotestosterona. Este receptor juega un papel crucial en el desarrollo y mantenimiento de las características masculinas, así como en la regulación de varios procesos fisiológicos, incluyendo el crecimiento muscular, la libido y la densidad ósea. Los inhibidores del receptor de andrógenos son ampliamente estudiados en el contexto del cáncer de próstata, donde la señalización del AR a menudo está sobreexpresada. En CymitQuimica, ofrecemos una gama de moduladores del receptor de andrógenos de alta calidad para apoyar su investigación en endocrinología, biología del cáncer y regulación hormonal.
Se han encontrado 230 productos para "Receptor de andrógenos".
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UT-34
CAS:UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wildFórmula:C15H12F4N4O2Pureza:98.12%Forma y color:SolidPeso molecular:356.275Nilutamide
CAS:Nilutamide, a nonsteroidal anti-androgen, treats prostate cancer by blocking androgen receptors, not affecting other hormone receptors.Fórmula:C12H10F3N3O4Pureza:98.67% - 99.78%Forma y color:Crystalline SolidPeso molecular:317.22072,2,5,7,8-Pentamethyl-6-Chromanol
CAS:2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation andFórmula:C14H20O2Pureza:98.72% - 98.72%Forma y color:SolidPeso molecular:220.3074AR antagonist 1
CAS:AR antagonist 1 is a potent antagonist of the androgen receptor.Fórmula:C15H19ClN2OPureza:98.96%Forma y color:White SolidPeso molecular:278.777Bicalutamide
CAS:Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting theFórmula:C18H14F4N2O4SPureza:98% - 99.87%Forma y color:SolidPeso molecular:430.37UT-155
CAS:UT-155 is a selective and potent antagonist of the androgen receptor (AR) (Ki: 267 nM for UT-155 binding to AR-LBD).Fórmula:C20H15F4N3O2Pureza:98.94%Forma y color:White SolidPeso molecular:405.3456Luxdegalutamide
CAS:Luxdegalutamide (ARV-766) is an orally available and effective protein degrader of protein hydrolysis-targeted chimeras (PROTAC).Luxdegalutamide degrades theFórmula:C45H54FN7O6Pureza:99.95%Forma y color:White SolidPeso molecular:807.952Topilutamide
CAS:Topilutamide (Fluridil) is a topical nonsteroidal antiandrogen.Fórmula:C13H11F6N3O5Pureza:99.22% - 99.93%Forma y color:SolidPeso molecular:403.234Adrenosterone
CAS:Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Fórmula:C19H24O3Pureza:98.13% - 98.29%Forma y color:SolidPeso molecular:300.39Proxalutamide
CAS:Proxalutamide is a potent antagonist of the androgen receptor (AR).Fórmula:C24H19F4N5O2SPureza:99.11%Forma y color:SolidPeso molecular:517.499Adrenocorticotropic hormone TFA
Adrenocorticotropic hormone TFA is an adrenocorticotropic hormone involved in neurohormonal regulation of the body.Pureza:99.71%Forma y color:White SolidZanoterone
CAS:Zanoterone is an AR antagonist (androgen receptor).Zanoterone has antitumor activity for the treatment of genitourinary disorders and oncological disorders andFórmula:C23H32N2O3SPureza:99.03% - 99.92%Forma y color:White SolidPeso molecular:416.577Cyproterone acetate
CAS:Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues andFórmula:C24H29ClO4Pureza:98.43% - 99.83%Forma y color:White SolidPeso molecular:416.94SK33
CAS:SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.Fórmula:C20H13F9N2O3Pureza:99.66%Forma y color:SolidPeso molecular:500.3144Flutamide
CAS:Flutamide (SCH 13521) is an antiandrogen with about the same potency as cyproterone in rodent and canine species.Fórmula:C11H11F3N2O3Pureza:99.6% - 99.96%Forma y color:SolidPeso molecular:276.21Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Fórmula:C24H32O4SPureza:99.87%Forma y color:White PowderPeso molecular:416.5733,3'-Diindolylmethane
CAS:3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.Fórmula:C17H14N2Pureza:99.09%Forma y color:SolidPeso molecular:246.3065ORM-15341
CAS:ORM-15341 is a potent and full antagonist for human AR (hAR)( with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells)Fórmula:C19H17ClN6O2Pureza:98.01%Forma y color:SolidPeso molecular:396.83Medroxyprogesterone Acetate
CAS:Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. Farlutin is a long-acting contraceptive.Fórmula:C24H34O4Pureza:99.44% - 99.92%Forma y color:White SolidPeso molecular:386.5244N-Desmethyl-Apalutamide
CAS:N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite.Fórmula:C20H13F4N5O2SPureza:98.6%Forma y color:SolidPeso molecular:463.408
