PDE
Las fosfodiesterasas (PDEs) son enzimas que hidrolizan nucleótidos cíclicos, como el AMPc y el GMPc, en sus formas inactivas, desempeñando un papel clave en la regulación de las vías de señalización intracelular. Los inhibidores de PDE se utilizan en el tratamiento de diversas afecciones, como enfermedades cardiovasculares, disfunción eréctil y trastornos respiratorios, debido a su capacidad para modular los niveles de nucleótidos cíclicos. En CymitQuimica, ofrecemos una gama de inhibidores de PDE para apoyar su investigación en señalización celular, farmacología y desarrollo terapéutico.
Se han encontrado 165 productos de "PDE"
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PDE IV-IN-1
CAS:<p>PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease</p>Fórmula:C20H23ClN4O2Pureza:99.79%Forma y color:SolidPeso molecular:386.88Tanimilast
CAS:<p>Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.</p>Fórmula:C30H30Cl2F2N2O8SPureza:98.34%Forma y color:SolidPeso molecular:687.54uk-50001
CAS:<p>UK-50001 is a PDE4 inhibitor for treating inflammation, allergies, respiratory issues, and wounds.</p>Fórmula:C26H24F3N3O4Pureza:99.90%Forma y color:SolidPeso molecular:499.48PDE4B-IN-2
CAS:<p>PDE4B-IN-2 (A 33), an oral PDE4B inhibitor, IC50: 15 nM; less potent on PDE4D (IC50: 1.7 µM), has anti-inflammatory properties.</p>Fórmula:C19H18ClN3O2SPureza:99.32%Forma y color:SolidPeso molecular:387.88Nanterinone
CAS:<p>Nanterinone: oral phosphodiesterase inhibitor, improves acute heart failure hemodynamics.</p>Fórmula:C15H15N3OPureza:99.53%Forma y color:SolidPeso molecular:253.3Dovramilast
CAS:<p>Dovramilast (CC-11050) is a PDE4 inhibitor that reduces the production of pro-inflammatory mediators in lupus erythematosus.</p>Fórmula:C24H28N2O6SPureza:98.75% - 99.62%Forma y color:SolidPeso molecular:472.55Verofylline
CAS:<p>Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for the</p>Fórmula:C12H18N4O2Pureza:98.33% - 98.83%Forma y color:SolidPeso molecular:250.3Carbazeran
CAS:<p>Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases.</p>Fórmula:C18H24N4O4Pureza:99.3%Forma y color:SolidPeso molecular:360.41AWD 12-281
CAS:<p>AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).</p>Fórmula:C22H14Cl2FN3O3Pureza:99.25% - 99.85%Forma y color:SolidPeso molecular:458.27Autotaxin-IN-3
CAS:<p>Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.</p>Fórmula:C22H21N9O2Pureza:99.54% - 99.79%Forma y color:SolidPeso molecular:443.46Filaminast
CAS:<p>Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.</p>Fórmula:C15H20N2O4Pureza:98.53% - 98.93%Forma y color:SolidPeso molecular:292.33MK-0873
CAS:<p>MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.</p>Fórmula:C25H18N4O3Pureza:98.40%Forma y color:SolidPeso molecular:422.44Mopidamol
CAS:<p>Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental</p>Fórmula:C19H31N7O4Pureza:99.05% - 99.78%Forma y color:SolidPeso molecular:421.49Isomazole
CAS:<p>Isomazole is a novel orally available phosphodiesterase (PDE) inhibitor with calcium-sensitizing properties that inhibits PDE3 and PDE4.</p>Fórmula:C14H13N3O2SPureza:98.66%Forma y color:SolidPeso molecular:287.34Tofimilast
CAS:<p>Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.</p>Fórmula:C18H21N5SPureza:99.55%Forma y color:SolidPeso molecular:339.46Dasantafil
CAS:<p>Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.</p>Fórmula:C22H28BrN5O5Pureza:99.4% - 99.50%Forma y color:SolidPeso molecular:522.39PF-04447943
CAS:<p>PF-04447943, a selective PDE9A inhibitor (IC50=12nM), may aid sickle cell anemia research with its anti-inflammatory properties.</p>Fórmula:C20H25N7O2Pureza:99.36% - 99.59%Forma y color:SolidPeso molecular:395.46GSK356278
CAS:<p>GSK356278: selective PDE4A/B/D inhibitor, pIC50~8.7, anti-inflammatory, anxiolytic, cognition-enhancing.</p>Fórmula:C21H25N7O2SPureza:99.90% - 99.97%Forma y color:SolidPeso molecular:439.53MK-8189
CAS:<p>MK-8189 is a potent and selective pyrimidine PDE10A inhibitor, with excellent PDE (phosphodiesterase) selectivity for the treatment of schizophrenia.</p>Fórmula:C19H22N6OSPureza:99.38% - 99.67%Forma y color:SolidPeso molecular:382.48Autotaxin-IN-5
CAS:<p>Autotaxin-IN-5 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.</p>Fórmula:C30H29N9O2Pureza:98%Forma y color:SolidPeso molecular:547.61
