PDE
Las fosfodiesterasas (PDEs) son enzimas que hidrolizan nucleótidos cíclicos, como el AMPc y el GMPc, en sus formas inactivas, desempeñando un papel clave en la regulación de las vías de señalización intracelular. Los inhibidores de PDE se utilizan en el tratamiento de diversas afecciones, como enfermedades cardiovasculares, disfunción eréctil y trastornos respiratorios, debido a su capacidad para modular los niveles de nucleótidos cíclicos. En CymitQuimica, ofrecemos una gama de inhibidores de PDE para apoyar su investigación en señalización celular, farmacología y desarrollo terapéutico.
Se han encontrado 166 productos de "PDE"
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Anti-ALDH7A1 Antibody (3P955)
<p>Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.</p>Forma y color:Odour LiquidAnti-ALDH7A1 Antibody (5P692)
<p>Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.</p>Forma y color:Odour LiquidBay 60-7550
CAS:Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.Fórmula:C27H32N4O4Pureza:98.14%Forma y color:SolidPeso molecular:476.57ENPP1 Inhibitor C
CAS:<p>ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.</p>Fórmula:C15H18N6Pureza:99.28%Forma y color:SolidPeso molecular:282.34PF-05180999
CAS:<p>α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.</p>Fórmula:C19H17F3N8Pureza:99.43% - 99.82%Forma y color:SolidPeso molecular:414.39Anti-ALDH7A1 Antibody (6G475)
<p>Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.</p>Forma y color:Odour LiquidDNMDP
CAS:DNMDP is a potent and selective PDE3A inhibitor with anticancer activity. It binds to PDE3A, promoting its interaction with Schlafen 12 (SLFN12).Fórmula:C15H20N4O3Forma y color:SolidPeso molecular:304.34BAY 73-6691 racemate
CAS:<p>BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.</p>Fórmula:C15H12ClF3N4OForma y color:SolidPeso molecular:356.73PF-05085727
CAS:<p>PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.</p>Fórmula:C20H18F3N7Pureza:98%Forma y color:SolidPeso molecular:413.4Crisaborole
CAS:<p>Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.</p>Fórmula:C14H10BNO3Pureza:99.70%Forma y color:SolidPeso molecular:251.05Ensifentrine
CAS:<p>Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), that</p>Fórmula:C26H31N5O4Pureza:99.76% - 99.94%Forma y color:SolidPeso molecular:477.56Ibudilast
CAS:<p>Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.</p>Fórmula:C14H18N2OPureza:99.83% - >99.99%Forma y color:White SolidPeso molecular:230.31PQ-10
CAS:<p>PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.</p>Fórmula:C22H21N5O3Pureza:99.86%Forma y color:SolidPeso molecular:403.43Z-HA155
CAS:<p>Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.</p>Fórmula:C24H19BFNO5SPureza:99.18%Forma y color:SolidPeso molecular:463.29HA 155
CAS:<p>HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.</p>Fórmula:C24H19BFNO5SPureza:99.88%Forma y color:SolidPeso molecular:463.29PF-8380
CAS:<p>PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).</p>Fórmula:C22H21Cl2N3O5Pureza:98.70% - 99.25%Forma y color:SolidPeso molecular:478.33RS-25344 hydrochloride
CAS:<p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>Fórmula:C19H14ClN5O4Pureza:99.25%Forma y color:SolidPeso molecular:411.8SEP-0372814
CAS:<p>SEP-0372814 is a potent inhibitor of PDE10.</p>Fórmula:C21H19N7Pureza:99.29%Forma y color:SolidPeso molecular:369.42IBMX
CAS:<p>IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM</p>Fórmula:C10H14N4O2Pureza:98% - >99.99%Forma y color:Off-WhitePeso molecular:222.24ML-030
CAS:<p>ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.</p>Fórmula:C20H20N4O4SPureza:97.93%Forma y color:SolidPeso molecular:412.46
