Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(450 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(50 productos)
- p97(14 productos)
Mostrar 3 subcategorías más
Se han encontrado 1044 productos de "Proteasas / Proteasoma"
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Rolipram
CAS:Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.Fórmula:C16H21NO3Pureza:99.22% - >99.99%Forma y color:SolidPeso molecular:275.34NSC 405020
CAS:<p>NSC 405020 is a noncatalytic inhibitor of MT1-MMP.</p>Fórmula:C12H15Cl2NOPureza:96.93% - 99.07%Forma y color:SolidPeso molecular:260.16Talabostat mesylate
CAS:<p>Talabostat mesylate (PT100): Oral DPP4 inhibitor, IC50 0.18 nM, targets tumor-linked proteins, boosts hematopoiesis.</p>Fórmula:C10H23BN2O6SPureza:98% - 99.91%Forma y color:SolidPeso molecular:310.18FT011
CAS:<p>FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.</p>Fórmula:C20H17NO5Pureza:98.98%Forma y color:SolidPeso molecular:351.35Saxagliptin
CAS:<p>Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.</p>Fórmula:C18H25N3O2Pureza:99.17% - 99.95%Forma y color:SolidPeso molecular:315.41HZ-1157
CAS:<p>HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.</p>Fórmula:C12H16N4OPureza:98.23%Forma y color:SolidPeso molecular:232.28Doravirine
CAS:<p>Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.</p>Fórmula:C17H11ClF3N5O3Pureza:99.65% - 99.79%Forma y color:SolidPeso molecular:425.75Balicatib
CAS:<p>Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.</p>Fórmula:C23H33N5O2Pureza:97.78% - 98.17%Forma y color:White To Off-White Solid PowderPeso molecular:411.544-Isopropylcatechol
CAS:<p>4-Isopropylcatechol is a potent depigmenting agent and is of use in the topical therapy of selected patients with hypermelanosis.</p>Fórmula:C9H12O2Pureza:97.93%Forma y color:SolidPeso molecular:152.19PythiDC
CAS:<p>PythiDC is a selective collagen prolyl 4-hydroxylase inhibitor, neither causing general toxicity nor disrupting iron homeostasis.</p>Fórmula:C10H6N2O4SPureza:98.13%Forma y color:SolidPeso molecular:250.23RN-18
CAS:<p>RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).</p>Fórmula:C20H16N2O4SPureza:97.21% - 98.39%Forma y color:SolidPeso molecular:380.42CeMMEC13
CAS:<p>CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).</p>Fórmula:C19H16N2O4Pureza:98.52%Forma y color:SolidPeso molecular:336.34Dabigatran
CAS:<p>Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.</p>Fórmula:C25H25N7O3Pureza:97.44% - 98.7%Forma y color:Tan SolidPeso molecular:471.51CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)
<p>CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9.</p>Fórmula:C54H75N13O16S2Pureza:99.71%Forma y color:SolidPeso molecular:1226.39Coblopasvir
CAS:<p>Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.</p>Fórmula:C41H50N8O8Pureza:99.33%Forma y color:SolidPeso molecular:782.88Belnacasan
CAS:Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Fórmula:C24H33ClN4O6Pureza:96.53% - 99.5%Forma y color:SolidPeso molecular:508.99VCH-916 free acid(1200133-34-1 free base)
CAS:<p>VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.</p>Fórmula:C26H37NO4SPureza:98.45%Forma y color:SolidPeso molecular:459.64Chlorcyclizine
CAS:<p>CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.</p>Fórmula:C18H21ClN2Pureza:98.75%Forma y color:SolidPeso molecular:300.83(Arg)9 TFA (143413-47-2 free base)
CAS:(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.Fórmula:C56H111F3N36O12Pureza:>99.99%Forma y color:SolidPeso molecular:1537.71HIV-1 Inhibitor 18A
CAS:<p>HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.</p>Fórmula:C14H11N5O2SPureza:99.79%Forma y color:SolidPeso molecular:313.33GK921
CAS:<p>GK921 is a transglutaminase 2 (TGase) inhibitor.</p>Fórmula:C21H20N4OPureza:97.44% - 99.49%Forma y color:SolidPeso molecular:344.41KGP94
CAS:<p>KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.</p>Fórmula:C14H12BrN3OSPureza:99.6%Forma y color:SolidPeso molecular:350.23Marimastat
CAS:<p>Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.</p>Fórmula:C15H29N3O5Pureza:97.46% - 98.11%Forma y color:SolidPeso molecular:331.41Histatin 5 acetate
<p>Histatin 5 acetate inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.</p>Fórmula:C135H199N51O35Pureza:98.72%Forma y color:SolidPeso molecular:3096.35Y-29794 Tosylate
CAS:<p>Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.</p>Fórmula:C30H42N2O4S3Pureza:99.86%Forma y color:SolidPeso molecular:590.86Hepln-13
CAS:<p>Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.</p>Fórmula:C17H13BrN2Pureza:97.67%Forma y color:SolidPeso molecular:325.2Proteinase K
CAS:<p>Proteinase K (Protease K) is a non-specific serine protease. Proteinase K hydrolyzes peptide bonds and is used for protein digestion. Cost-effective and quality-assured.</p>Fórmula:C29H27N2O12PPureza:98%Forma y color:SolidPeso molecular:626.511Thiamine disulfide
CAS:<p>Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.</p>Fórmula:C24H34N8O4S2Pureza:99.81%Forma y color:CoaPeso molecular:562.71Omarigliptin
CAS:Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.Fórmula:C17H20F2N4O3SPureza:99.68% - 99.77%Forma y color:SolidPeso molecular:398.43Delavirdine mesylate
CAS:<p>Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).</p>Fórmula:C23H32N6O6S2Pureza:99.99%Forma y color:Light Brown SolidPeso molecular:552.67PSI-6206
CAS:<p>PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.</p>Fórmula:C10H13FN2O5Pureza:98% - 99.79%Forma y color:SolidPeso molecular:260.22Rusalatide acetate (497221-38-2 free base)
CAS:<p>Rusalatide acetate (TP508 amide acetate), a regenerated peptide, alleviates radiation-induced gastrointestinal injury by activating stem cells.</p>Fórmula:C99H151N29O37SPureza:>99.99%Forma y color:SolidPeso molecular:2371.5Ivachtin
CAS:<p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>Fórmula:C20H21N3O7SPureza:99.74%Forma y color:SolidPeso molecular:447.46JNJ0966
CAS:<p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>Fórmula:C16H16N4O2S2Pureza:99.46% - 99.62%Forma y color:SolidPeso molecular:360.45Methylchloroisothiazolinone/Methylisothiazolinone Mixture
CAS:<p>Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.</p>Fórmula:C8H9ClN2O2S2Forma y color:SolidPeso molecular:264.75KP-457
CAS:<p>KP-457 is a ADAM17 and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).</p>Fórmula:C21H24N2O7S2Pureza:98.33%Forma y color:SolidPeso molecular:480.56Sitagliptin phosphate monohydrate
CAS:<p>Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.</p>Fórmula:C16H15F6N5O·H3PO4·H2OPureza:99.85% - 99.98%Forma y color:White Or Almost White Crystalline PowderPeso molecular:523.33Rilpivirine HCl
CAS:<p>Rilpivirine HCl (Rilpivirine hydrochloride) is an NNRTI inhibitor with antiviral activity that inhibits the HIV virus.</p>Fórmula:C22H19ClN6Pureza:99.48%Forma y color:SolidPeso molecular:402.88(1S,2R)-Alicapistat
CAS:<p>(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.</p>Fórmula:C25H27N3O4Pureza:99.60%Forma y color:SoildPeso molecular:433.5Teneligliptin
CAS:<p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>Fórmula:C22H30N6OSPureza:99.73%Forma y color:SolidPeso molecular:426.58Ledipasvir
CAS:<p>Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.</p>Fórmula:C49H54F2N8O6Pureza:99.96%Forma y color:SolidPeso molecular:889(R)-Trolox
CAS:(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.Fórmula:C14H18O4Pureza:99.88%Forma y color:SolidPeso molecular:250.29Danoprevir
CAS:<p>Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).</p>Fórmula:C35H46FN5O9SPureza:98% - 99.35%Forma y color:SolidPeso molecular:731.83Nelfinavir
CAS:<p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>Fórmula:C32H45N3O4SPureza:98.16% - 99.5%Forma y color:White To Off-White Crystalline PowderPeso molecular:567.78PSI
CAS:<p>PSI is a proteasome inhibitor.</p>Fórmula:C32H50N4O8Pureza:97% - 98.33%Forma y color:SolidPeso molecular:618.76Galegenimab
CAS:<p>Galegenimab (FHTR 2163; RG 6147; RO 7171009) is an HTRA1 antibody fragment for AMD research.</p>Pureza:95% - 95%Forma y color:LiquidTriton X-45(n=4)
CAS:<p>Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.</p>Fórmula:C22H38O5Forma y color:SolidPeso molecular:382.53Lanadelumab
CAS:<p>Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.</p>Pureza:95% - 95%Forma y color:LiquidZampilimab
CAS:<p>Zampilimab (UCB-7858) is a humanised monoclonal antibody targeting TGM2, inhibits the cross-linking transamidase activity of TG2, renal fibrosis.</p>Pureza:95%Forma y color:LiquidKZR-504
CAS:KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).Fórmula:C21H23N3O6Forma y color:SolidPeso molecular:413.42
