Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(96 productos)
- DPP-4(20 productos)
- Glutaminasa(40 productos)
- Proteasa del VIH(450 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(53 productos)
- Proteasoma(94 productos)
- Serina proteasa(50 productos)
- p97(14 productos)
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Se han encontrado 1044 productos de "Proteasas / Proteasoma"
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PR 39 (porcine) acetate
<p>PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.</p>Pureza:98%Forma y color:LiquidPeso molecular:N/A6-Acetylnimbandiol
CAS:<p>6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.</p>Fórmula:C28H34O8Forma y color:SolidPeso molecular:498.56Zetomipzomib maleate
CAS:<p>Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.</p>Fórmula:C34H46N4O12Forma y color:SolidPeso molecular:702.758Rivulariapeptolides 1185
<p>Rivulariapeptolides 1185 inhibits serine proteases; IC50: chymotrypsin 13.17 nM, elastase 23.59 nM, proteinase K 55.26 nM.</p>Fórmula:C61H87N9O15Forma y color:SolidPeso molecular:1186.39L 659286
CAS:<p>L 659286 is one kind of cephalosporin derivative.</p>Fórmula:C17H21N5O7S2Forma y color:SolidPeso molecular:471.51Pseudostellarin G
CAS:<p>Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.</p>Fórmula:C42H56N8O9Forma y color:SolidPeso molecular:816.94Rivulariapeptolides 988
<p>Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).</p>Fórmula:C50H68N8O13Forma y color:SolidPeso molecular:989.12Ellipyrone A
<p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>Fórmula:C25H34O8Forma y color:SolidPeso molecular:462.53CRA-2059
CAS:<p>CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.</p>Fórmula:C34H46N12O8Pureza:97.68%Forma y color:SolidPeso molecular:750.818Emtricitabine S-oxide
CAS:Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.Fórmula:C8H10FN3O4SPureza:98%Forma y color:SolidPeso molecular:263.25Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFórmula:C47H64N14O10Forma y color:SolidPeso molecular:985.1H-Gly-Pro-Hyp-OH
CAS:<p>H-Gly-Pro-Hyp-OH is a potent and oral anti-photoaging collagen peptide and improves the hydration of human skin, elasticity and anti-wrinkle properties.</p>Fórmula:C12H19N3O5Pureza:98.47%Forma y color:SolidPeso molecular:285.3Phaeosphaone D
CAS:<p>Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).</p>Fórmula:C20H27N3O3S2Forma y color:SolidPeso molecular:421.58CTS-1027
CAS:CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.Fórmula:C19H20ClNO6SForma y color:SolidPeso molecular:425.88Tenofovir hydrate
CAS:<p>Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.</p>Fórmula:C9H16N5O5PPureza:99.63%Forma y color:SolidPeso molecular:305.23S-Methylglutathione
CAS:<p>S-Methylglutathione (S-Methyl glutathione) is a 1-chloro-2,4-dinitrobenzene coupling inhibitor, an XOCl scavenger, and inhibitor of glyoxalase 1.</p>Fórmula:C11H19N3O6SPureza:98%Forma y color:SolidPeso molecular:321.35E-64d [for Biochemical Research]
CAS:Fórmula:C17H30N2O5Pureza:>95.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:342.44Ilomastat
CAS:Fórmula:C20H28N4O4Pureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:388.47Retagliptin
CAS:<p>Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.</p>Fórmula:C19H18F6N4O3Forma y color:SolidPeso molecular:464.36PSI-6206 13C,d3
CAS:<p>PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.</p>Fórmula:C10H13FN2O5Pureza:98%Forma y color:SolidPeso molecular:264.23MMP-8 Inhibitor I
CAS:<p>MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.</p>Fórmula:C17H18N2O5SForma y color:SolidPeso molecular:362.4Tilpisertib
CAS:<p>Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).</p>Fórmula:C33H33ClN8OForma y color:SolidPeso molecular:593.13Teneligliptin hydrobromide hydrate
CAS:<p>Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.</p>Fórmula:C22H33BrN6O2SForma y color:SolidPeso molecular:525.51Glutaminase-IN-3
CAS:<p>Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.</p>Fórmula:C19H19F3N6O2SPureza:98.51%Forma y color:SolidPeso molecular:452.45Tripeptide-32
CAS:<p>Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].</p>Fórmula:C12H22N4O5Pureza:98%Forma y color:SolidPeso molecular:302.33Sitagliptin fenilalanil
CAS:Sitagliptin fenilalanil is a dipeptidyl aminopeptidase (DPP-4) inhibitor.Fórmula:C25H24F6N6O2Forma y color:SolidPeso molecular:554.49PKSI-527
CAS:<p>PKSI-527 inhibits plasma kallikrein (Ki=0.81μM), selective vs. glandular kallikrein/thrombin/urokinase/Xa, reduces bradykinin, affects clotting times.</p>Fórmula:C25H32ClN3O4Forma y color:SolidPeso molecular:473.99H-Arg-4MβNA
CAS:H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.Fórmula:C17H23N5O2Pureza:99.98%Forma y color:SolidPeso molecular:329.4BAY-677
CAS:<p>BAY-677, an inactive counterpart to BAY-678, inhibits human neutrophil elastase with 20 nM IC50 and is an SGC-nominated probe.</p>Fórmula:C20H15F3N4O2Forma y color:SolidPeso molecular:400.355-Amino-8-hydroxyquinoline
CAS:<p>5-Amino-8-hydroxyquinoline(5A8HQ),Proteasome inhibitor. Potential anticancer agent.</p>Fórmula:C9H8N2OPureza:99.69%Forma y color:SolidPeso molecular:160.176-Chloro-7-deazapurine-2F-β-D-arabinofuranose
CAS:<p>6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.</p>Fórmula:C11H11ClFN3O3Forma y color:SolidPeso molecular:287.67(Arg)9
CAS:(Arg)9 (Nona-L-arginine;Peptide R9) is a cell-penetrating peptide,and exhibits neuroprotective activity(IC50 of 0.78 μM, in the glutamic acid model).Fórmula:C54H110N36O10Forma y color:SolidPeso molecular:1423.69Dabigatran ethyl ester
CAS:<p>Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.</p>Fórmula:C27H29N7O3Pureza:99.98%Forma y color:SolidPeso molecular:499.56Ubenimex Hydrochloride [for Biochemical Research]
CAS:Fórmula:C16H24N2O4·HClPureza:>97.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:344.84PD-166793
CAS:<p>PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.</p>Fórmula:C17H18BrNO4SPureza:99.86%Forma y color:SolidPeso molecular:412.3Teneligliptin D8
CAS:<p>Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.</p>Fórmula:C22H30N6OSPureza:98%Forma y color:SolidPeso molecular:434.63Tomeglovir
CAS:Tomeglovir is a potent anti-CMV agent, inhibiting the processing of viral DNA-concatemers (IC50s: 0.34/0.039 μM for HCMV and MCMV).Fórmula:C23H27N3O4SPureza:98%Forma y color:SolidPeso molecular:441.54DMP 777
CAS:DMP 777 is an orally active inhibitor of human leukocyte elastase.Fórmula:C31H40N4O6Forma y color:SolidPeso molecular:564.67Thrombin inhibitor 5
CAS:<p>Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.</p>Fórmula:C11H9FN4O3Pureza:99.58%Forma y color:SolidPeso molecular:264.21H-Pro-Lys-OH TFA
<p>H-Pro-Lys-OH TFA is a dipeptide composed of proline and lysine, serving as a substrate for imino dipeptidase (prolinase). Additionally, it can be utilized in peptide synthesis.</p>Fórmula:C13H22F3N3O5Forma y color:SolidPeso molecular:357.332'-β-C-Ethynyladenosine
CAS:<p>2'-β-C-Ethynyladenosine is a nucleoside analog that potently inhibits hepatitis C virus (HCV) replication by targeting the viral NS5B polymerase.</p>Fórmula:C12H13N5O4Forma y color:SolidPeso molecular:291.26Sivelestat Sodium Tetrahydrate
CAS:Fórmula:C20H21N2NaO7S·4H2OPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:528.50Urokinase
CAS:<p>Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.</p>Forma y color:SolidTrisodium Hydrogen Ethylenediaminetetraacetate Hydrate [for Biochemical Research]
CAS:Fórmula:C10H13N2Na3O8·xH2OPureza:>98.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:358.19 (as Anhydrous)Anguizole
CAS:Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B.Fórmula:C17H11ClF2N4O2SForma y color:SolidPeso molecular:408.81Pepstatin A
CAS:Fórmula:C34H63N5O9Pureza:>90.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:685.90(-)-Gallocatechin Gallate
CAS:Fórmula:C22H18O11Pureza:>95.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:458.38Tanaproget
CAS:Tanaproget is an orally available, high-affinity, non-steroidal progesterone receptor (PR) agonist with an IC50 of 1.7 nM for hPR.Fórmula:C16H15N3OSPureza:98%Forma y color:SolidPeso molecular:297.38Ubenimex
CAS:Fórmula:C16H24N2O4Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:308.38LN5P45
<p>LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1</p>Fórmula:C13H15ClN2O2Forma y color:SolidPeso molecular:266.72
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