Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(36 productos)
- Cisteína proteasa(110 productos)
- DPP-4(20 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(502 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(95 productos)
- Serina proteasa(56 productos)
- p97(15 productos)
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Se han encontrado 1092 productos de "Proteasas / Proteasoma"
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AL-611
CAS:<p>AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).</p>Fórmula:C25H33F2N6O8PForma y color:SolidPeso molecular:614.544TP0597850
CAS:TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].Fórmula:C41H57N9O13SForma y color:SolidPeso molecular:916.01Ac-PAL-AMC
CAS:Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.Fórmula:C26H34N4O6Forma y color:SolidPeso molecular:498.57Acetyl-Calpastatin (184-210)(human) acetate
<p>Acetyl-Calpastatin acetate inhibits µ-calpain (Ki=0.2nM) and cathepsin L (Ki=6μM) selectively and reversibly.</p>Fórmula:C144H234N36O46SPureza:97.84% - 98.16%Forma y color:SolidPeso molecular:3237.68MMP-3 Inhibitor acetate
MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.Fórmula:C29H50N10O11SPureza:98%Forma y color:SolidPeso molecular:746.83Nostosin G
Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).Fórmula:C25H33N5O6Forma y color:SolidPeso molecular:499.56Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Fórmula:C19H14BrClN4OForma y color:SolidPeso molecular:429.7RJS308
<p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>Fórmula:C63H75N13O11SForma y color:SolidPeso molecular:1222.42GCPII-IN-1
CAS:<p>GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.</p>Fórmula:C12H21N3O7Forma y color:SolidPeso molecular:319.314Ecallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention ofForma y color:Odour Solid(Iso)-Fosdevirine
CAS:(Iso)-Fosdevirine ( (Iso)-GSK2248761), a reverse transcriptase (NNRTI) inhibitor with anti-HIV activity, is used in the study of neurological diseases.Fórmula:C20H17ClN3O3PPureza:99.93%Forma y color:SoildPeso molecular:413.796,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFórmula:C30H42N2O4SForma y color:SolidPeso molecular:526.73ZG36
ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrialForma y color:Odour SolidHCVP-IN-1
CAS:HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.Fórmula:C30H34FN5O3Forma y color:SolidPeso molecular:531.632Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFórmula:C47H64N14O10Forma y color:SolidPeso molecular:985.1Carboxypeptidase C
CAS:Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.Forma y color:SolidAlisporivir
CAS:Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.Fórmula:C63H113N11O12Pureza:99.95%Forma y color:SolidPeso molecular:1216.64Acetyl-Calpastatin(184-210)(human) TFA
Acetyl-Calpastatin(184-210)(human) TFA inhibits μ-calpain (Ki 0.2 nM) and cathepsin L (Ki 6 μM) selectively and reversibly.Fórmula:C144H231F3N36O46SForma y color:SolidPeso molecular:3291.65RXP470
CAS:RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).Fórmula:C35H35BrClN4O10PForma y color:SolidPeso molecular:818Befovacimab
CAS:<p>Befovacimab, a human IgG2 antibody, targets TFPI for hemophilia A/B research.</p>Forma y color:Liquid
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