Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1092 productos de "Proteasas / Proteasoma"

Pureza (%)

100

productos por página.

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NIM811
CAS:
- 143205-42-9
NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
Fórmula:C₆₂H₁₁₁N₁₁O₁₂
Pureza:98%
Forma y color:Solid
Peso molecular:1202.635
Ref: TM-T12226
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Rivulariapeptolides 1155
Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).
Fórmula:C₅₉H₈₁N₉O₁₅
Forma y color:Solid
Peso molecular:1156.33
Ref: TM-T75648
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HB-2-30
CAS:
- 3031522-14-9
HB-2-30 is a far-red fluorescent transglutaminase 2 (TG2) probe for in vitro and in vivo endocytosis imaging. HB-2-30 complexes with TG2 and α2-macroglobulin for efficient endocytosis via the LRP1 pathway.
Fórmula:C₆₆H₈₆N₁₀O₁₄S₂
Peso molecular:1307.58
Ref: TM-T204998
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CL 82198 hydrochloride
CAS:
- 1188890-36-9
CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.
Fórmula:C₁₇H₂₃ClN₂O₃
Forma y color:Solid
Peso molecular:338.83
Ref: TM-T41179
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PSI-353661
CAS:
- 1231747-08-2
PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.
Fórmula:C₂₄H₃₂FN₆O₈P
Forma y color:Solid
Peso molecular:582.52
Ref: TM-T74301
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GSK2818713
CAS:
- 1422484-32-9
GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
Fórmula:C₄₆H₅₆N₈O₈
Forma y color:Solid
Peso molecular:849.002
Ref: TM-T38858
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VD2173
CAS:
- 2574389-19-6
VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.
Fórmula:C₃₁H₄₅N₉O₆S
Forma y color:Solid
Peso molecular:671.81
Ref: TM-T74390
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HIV-1 Rev (34-50)
CAS:
- 141237-50-5
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity.
Fórmula:C₉₇H₁₇₃N₅₁O₂₄
Pureza:99.91%
Forma y color:Solid
Peso molecular:2437.74
Ref: TM-TP1149
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HCV-IN-7 hydrochloride
CAS:
- 1449756-87-9
HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
Fórmula:C₄₀H₅₀Cl₂N₈O₆S
Pureza:98%
Forma y color:Solid
Peso molecular:841.85
Ref: TM-T11548L
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PPACK II
CAS:
- 74392-49-7
PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .
Fórmula:C₂₅H₃₃ClN₆O₃
Forma y color:Solid
Peso molecular:501.02
Ref: TM-T73863
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Recombinant Proteinase K
Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.
Forma y color:Solid
Ref: TM-T76202
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Ichorcumab
CAS:
- 2589583-20-8
Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Forma y color:Liquid
Ref: TM-T9901A-779
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Relacatib
CAS:
- 362505-84-8
Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.
Fórmula:C₂₇H₃₂N₄O₆S
Forma y color:Solid
Peso molecular:540.64
Ref: TM-T40463
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Tyrosinase/elastase-IN-1
Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase
Fórmula:C₃₃H₅₂O₅
Forma y color:Solid
Peso molecular:528.76
Ref: TM-T74243
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5-epi-Arvestonate A
CAS:
- 2767066-84-0
5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.
Fórmula:C₁₆H₂₆O₅
Forma y color:Solid
Peso molecular:298.37
Ref: TM-T75535
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PS 915
CAS:
- 86356-77-6
PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
Fórmula:C₂₇H₃₆ClN₇O₆
Pureza:98%
Forma y color:Solid
Peso molecular:590.08
Ref: TM-T24674
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Rivulariapeptolides 1121
Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).
Fórmula:C₅₆H₈₃N₉O₁₅
Forma y color:Solid
Peso molecular:1122.31
Ref: TM-T75650
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KKI-5
CAS:
- 97145-43-2
KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.
Fórmula:C₃₅H₅₅N₁₁O₉
Pureza:98%
Forma y color:Solid
Peso molecular:773.88
Ref: TM-TP1792
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Histargin
CAS:
- 93361-66-1
Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.
Fórmula:C₁₄H₂₅N₇O₄
Forma y color:Solid
Peso molecular:355.39
Ref: TM-T25504
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LXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.
Fórmula:C₂₇H₂₂FN₇O₆
Pureza:99.89%
Forma y color:Soild
Peso molecular:559.51
Ref: TM-T39214L