Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(51 productos)
- Cisteína proteasa(139 productos)
- DPP-4(91 productos)
- Glutaminasa(49 productos)
- Proteasa del VIH(505 productos)
- PAI-1(31 productos)
- Inhibidores de la proteasa(49 productos)
- Receptor activado por proteasa(57 productos)
- Proteasoma(71 productos)
- Serina proteasa(82 productos)
- p97(15 productos)
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Se han encontrado 929 productos para "Proteasas / Proteasoma".
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ALLM
CAS:ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].Fórmula:C19H35N3O4SPureza:98%Forma y color:SolidPeso molecular:401.56S 2160
CAS:S 2160 is a synthetic chromogenic substrate for thrombin.Fórmula:C33H40N8O6Forma y color:SolidPeso molecular:644.72NVP-DPP728 dihydrochloride
CAS:NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.Fórmula:C15H20Cl2N6OForma y color:SolidPeso molecular:371.27Isoleucylvaline
CAS:Isoleucylvaline is a dipeptide.Fórmula:C11H22N2O3Forma y color:SolidPeso molecular:230.30HCV-IN-30
CAS:HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).Fórmula:C36H44N6O4Pureza:99.6%Forma y color:White SolidPeso molecular:624.77AGG-523
CAS:AGG-523, an aggrecanase inhibitor, may slow cartilage wear after joint injury by reducing ARG-aggrecan in rats.Fórmula:C28H29FN2O4Forma y color:SolidPeso molecular:476.54Carboxypeptidase G2 (CPG2) Inhibitor
CAS:Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.Fórmula:C13H15NO6SPureza:99.96%Forma y color:SolidPeso molecular:313.33Cathepsin Inhibitor 1
CAS:Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.Fórmula:C20H24ClN5O2Pureza:99.78%Forma y color:SolidPeso molecular:401.89Ref: TM-T6015
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg144,00€25mg236,00€50mg371,00€100mg522,00€200mg743,00€L 722151
CAS:L 722151 is an FXIIIa inhibitor.Fórmula:C8H9ClN2O5S3Pureza:98%Forma y color:SolidPeso molecular:344.82ER 27319 maleate
CAS:Selective inhibitor of Syk kinaseFórmula:C22H24N2O5Pureza:98.45%Forma y color:Yellow SolidPeso molecular:396.44Diprotin B
CAS:Diprotin B is a dipeptidyl peptidase IV inhibitor.Fórmula:C16H29N3O4Pureza:98%Forma y color:SolidPeso molecular:327.42RLVT-14-02
RLVT-14-02 is a human monoclonal antibody (mAb) targeting MMP14. It is applicable in the study of neuropathic pain.ABX-MA1
CAS:ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.Eflumenibep alfa
CAS:Eflumenibep alfa is a kallikrein 5 (Kallikrein5) inhibitor with anti-inflammatory properties. This fusion protein consists of human SPINK2 and the human IgG1 Fc fragment connected at the C-terminus.REGN7999
REGN7999 is a monoclonal antibody that inhibits TMPRSS6. By suppressing TMPRSS6 activity, REGN7999 prevents HJV cleavage, enhancing BMP6-HJV signaling and increasing serum hepcidin levels. This inhibition aids in alleviating iron overload and impaired erythropoiesis in β-thalassemia mouse models. REGN7999 is applicable for research in β-thalassemia.Invobenitug
CAS:Invobenitug is a humanized IgG1κ monoclonal antibody that targets DPP3, with the corresponding isotype control being HumanIgG1kappa, Isotype Control.CM-338
CM-338 is a human monoclonal antibody (mAb) targeting MASP2. It is useful for research related to IgA nephropathy.Tyrosinase-IN-4
CAS:Tyrosinase-IN-4, a potent inhibitor, has uses in skin-whitening, food preservation, cosmetics, agriculture, and medicine.Fórmula:C15H9ClO3Forma y color:SolidPeso molecular:272.68YD-3
CAS:YD-3 is a PAR4 antagonist that significantly inhibits thrombin-induced platelet aggregation in rabbits (IC(50)=28.3 microM). In addition, YD-3 suppresses thrombin-induced proliferation of vascular smooth muscle cells (VSMCs) and reduces neointimal thickening after balloon injury. Through Ras- and ERK1/2-mediated signaling pathways, YD-3 impedes thrombin-driven VSMC proliferation. When analyzed with Western blot, YD-3 primarily inhibits thrombin-induced expression of vascular endothelial growth factor receptor 2 (Flk-1) without affecting extracellular signal-regulated kinase 1/2 phosphorylation. YD-3 could potentially have value in elucidating the pathophysiology of thrombin-induced angiogenesis.Fórmula:C23H20N2O2Forma y color:SolidPeso molecular:356.42MyoMed 205
CAS:MyoMed-205 is an inhibitor of MuRF1 (muscle ring finger protein 1) activity. It effectively prevents early diaphragm contractile dysfunction and atrophy following 12 hours of unilateral phrenic nerve denervation. By inhibiting MuRF1, MyoMed-205 reduces muscle protein ubiquitination and subsequent proteasome degradation. It also increases the protein levels of phosphorylated Akt (ser473), an essential signaling molecule for muscle growth and maintenance. MyoMed-205 is applicable in the research and treatment of diaphragm dysfunction and atrophy (DIDD) due to early disuse, particularly in clinical situations such as diaphragm paralysis or mechanical ventilation.Fórmula:C26H25N3O5SForma y color:SolidPeso molecular:491.56
