Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(36 productos)
- Cisteína proteasa(110 productos)
- DPP-4(22 productos)
- Glutaminasa(45 productos)
- Proteasa del VIH(507 productos)
- PAI-1(26 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(94 productos)
- Serina proteasa(55 productos)
- p97(15 productos)
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Se han encontrado 1058 productos de "Proteasas / Proteasoma"
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PSI
CAS:PSI is a proteasome inhibitor.Fórmula:C32H50N4O8Pureza:97% - 98.33%Forma y color:SolidPeso molecular:618.76Danoprevir
CAS:Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).Fórmula:C35H46FN5O9SPureza:98% - 99.80%Forma y color:SolidPeso molecular:731.83Triton X-45(n=4)
CAS:Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.Fórmula:C22H38O5Forma y color:SolidPeso molecular:382.53Anti-Human/Mouse denatured collagen type-I Antibody
Anti-Human/Mouse denatured collagen type-I Antibody (XL313) is an IgG1, κ inhibitor derived from mice, targeting denatured collagen type-I in both human and mouse.Forma y color:Odour LiquidLanadelumab
CAS:Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.Pureza:95% - 97.4% (SDS-PAGE); 99.2% (SEC-HPLC)Forma y color:LiquidGalegenimab
CAS:Galegenimab (RG 6147) is an Fab targeting HtrA1, capable of blocking proteolytic cleavage of biglycan (an HtrA1 substrate), suitable for AMD research.Pureza:95% - 95.8% (SDS-PAGE); 99.7% (SEC-HPLC)Forma y color:LiquidPeso molecular:46.87 kDaKZR-504
CAS:KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).Fórmula:C21H23N3O6Forma y color:SolidPeso molecular:413.42Anti-Matriptase Antibody
Anti-Matriptase Antibody is a human-derived antibody expressed in CHO cells, targeting Matriptase. It features a huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Matriptase Antibody can be found in HumanIgG1kappa, Isotype Control.Forma y color:Odour LiquidIsecarosmab
CAS:Isecarosmab (M6495) is a monoclonal antibody targeting ADAMTS-5, protect cartilage and inhibit ADAMTS-5-mediated degradation of aggrecan,osteoarthritis (OA).Pureza:95% - 98.0% (SDS-PAGE); 96.7% (SEC-HPLC)Forma y color:LiquidZampilimab
CAS:Zampilimab (UCB-7858) is a humanised monoclonal antibody targeting TGM2, inhibits the cross-linking transamidase activity of TG2, renal fibrosis.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaHCV-IN-30
CAS:HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).Fórmula:C36H44N6O4Pureza:99.6%Forma y color:SolidPeso molecular:624.77S 2160
CAS:S 2160 is a synthetic chromogenic substrate for thrombin.Fórmula:C33H40N8O6Forma y color:SolidPeso molecular:644.72Carboxypeptidase G2 (CPG2) Inhibitor
CAS:Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.Fórmula:C13H15NO6SPureza:99.96%Forma y color:SolidPeso molecular:313.33Cathepsin Inhibitor 1
CAS:<p>Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.</p>Fórmula:C20H24ClN5O2Pureza:99.78%Forma y color:SolidPeso molecular:401.89Tyrosinase-IN-6
CAS:Tyrosinase-IN-6 (4B) is a potent tyrosinase inhibitor (IC50=3.80 μM) with good antioxidant activity.Fórmula:C24H31N3O2Forma y color:SolidPeso molecular:393.52Alicapistat
CAS:Alicapistat (ABT-957) is a human calpains 1 and 2 inhibitor. It can potentially be used to treat Alzheimer's disease (AD).Fórmula:C25H27N3O4Pureza:98%Forma y color:SolidPeso molecular:433.5VEL-0230
CAS:VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.Fórmula:C14H24NNaO5Forma y color:SolidPeso molecular:309.33PK44 phosphate
CAS:PK44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50: 15.8 nM).Fórmula:C17H19F5N7O5PForma y color:SolidPeso molecular:527.349BAY8040
CAS:BAY8040 is a potent selective human neutrophilic elastase inhibitor with excellent potency and selectivity with promising pharmacokinetic characteristics.Fórmula:C21H16F3N5O2Forma y color:SolidPeso molecular:427.38AA10 TG2 inhibitor
CAS:AA10 is an irreversible inhibitor of transglutaminase 2 (TG2).Fórmula:C32H36N4O5Forma y color:SolidPeso molecular:556.65
