Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(36 productos)
- Cisteína proteasa(111 productos)
- DPP-4(24 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(501 productos)
- PAI-1(26 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(89 productos)
- Serina proteasa(54 productos)
- p97(15 productos)
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Se han encontrado 993 productos de "Proteasas / Proteasoma"
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MK-0674
CAS:MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.Fórmula:C26H27F6N3O2Pureza:97.3% - 99.91%Forma y color:SolidPeso molecular:527.5Nesbuvir
CAS:Nesbuvir: HCV NS5B polymerase inhibitor, IC50 9 nM against HCV 1b replicon in liver cancer cells.Fórmula:C22H23FN2O5SPureza:99.99%Forma y color:SolidPeso molecular:446.49Ref: TM-TQ0090
1mg60,00€2mg88,00€5mg133,00€10mg173,00€25mg301,00€50mg442,00€100mg577,00€200mg780,00€1mL*10mM (DMSO)147,00€Aderamastat
CAS:Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.Fórmula:C21H18N2O4SPureza:99.35%Forma y color:SolidPeso molecular:394.44VBY-825
CAS:VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.Fórmula:C23H29F4N3O5SPureza:99.91%Forma y color:SolidPeso molecular:535.55Faldaprevir sodium
CAS:Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.Fórmula:C40H48BrN6NaO9SForma y color:SolidPeso molecular:891.81Pyridoxatin
CAS:Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.Fórmula:C15H21NO3Forma y color:SolidPeso molecular:263.33PLGLAG
CAS:PLGLAG is a peptide chain that acts as a linker in activatable cell-penetrating peptides (ACPPs). ACPPs containing the PLGLAG linker are primarily sensitive to MMP-2 and MMP-9 in vivo. PLGLAG is applicable in cancer research.Fórmula:C24H42N6O7Forma y color:SolidPeso molecular:526.63MMP-13-IN-1
CAS:MMP-13-IN-1, with an IC50 value of 16 nM, is a potent and selective inhibitor of MMP-13, suitable for atherosclerosis research [1].Fórmula:C19H16F3N3O3Forma y color:SolidPeso molecular:391.34NAPAP
CAS:NAPAP is a thrombin inhibitor with potent anticoagulant activity (Ki: 2.1 nM). It selectively inhibits thrombin through a rapid binding mechanism while exhibiting weaker inhibition of trypsin, Factor Xa, and plasmin. NAPAP can be utilized for research into thrombotic conditions, including venous thrombosis and myocardial infarction.Fórmula:C27H31N5O4SForma y color:SolidPeso molecular:521.63Feniralstat
CAS:Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.Fórmula:C26H25F2N5O4Pureza:99.52%Forma y color:SolidPeso molecular:509.51MK-8876
CAS:MK-8876 is an Inhibitor of HCV NS5B Site D.Fórmula:C32H24F2N4O5SPureza:98%Forma y color:SolidPeso molecular:614.62RIPK1-IN-26
CAS:RIPK1-IN-26 is a potent inhibitor of Receptor-Interacting Serine/Threonine Kinase 1 (RIPK1), exhibiting anti-necrotic properties in cells. This compound demonstrates good metabolic stability and binding specificity in mice. RIPK1-IN-26 holds potential for development as a PET imaging probe and in the research of neurodegenerative diseases.Fórmula:C15H20FNO2Forma y color:SolidPeso molecular:265.32JBJ-08-178-01
CAS:JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2's kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.Fórmula:C31H30N8O3Forma y color:SolidPeso molecular:562.62Enantiomer of Sofosbuvir
Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.Fórmula:C22H29FN3O9PPureza:98%Forma y color:SolidPeso molecular:529.45CE-2072
CAS:CE-2072 is a synthetic host serine proteases inhibitor.Fórmula:C33H41N5O6Pureza:98%Forma y color:SolidPeso molecular:603.71Verducatib
CAS:Verducatib is an inhibitor of cathepsins (cathepsin).Fórmula:C31H35FN4O3Forma y color:SolidPeso molecular:530.633GB111-NH2
CAS:GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].Fórmula:C33H39N3O6Forma y color:SolidPeso molecular:573.68Matriptase-IN-2 free base
CAS:Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].Fórmula:C29H33Cl2N5O3SForma y color:SolidPeso molecular:602.58CatD-IN-1
CAS:CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM, and it shows potential for research in the field of osteoarthritis.Fórmula:C18H18Cl2N4O5Forma y color:SolidPeso molecular:441.265Tyrosinase-IN-20
CAS:Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].Fórmula:C17H18N2O2SForma y color:SolidPeso molecular:314.4
