Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(110 productos)
- DPP-4(20 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(501 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(95 productos)
- Serina proteasa(56 productos)
- p97(15 productos)
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Se han encontrado 1092 productos de "Proteasas / Proteasoma"
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5-epi-Arvestonate A
CAS:<p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>Fórmula:C16H26O5Forma y color:SolidPeso molecular:298.37JC-10
CAS:JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.Fórmula:C25H29Cl2IN4Pureza:95%Forma y color:SolidPeso molecular:583.34Linagliptin Methyldimer
CAS:Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.Fórmula:C50H56N16O4Pureza:99.91%Forma y color:SolidPeso molecular:945.08Rivulariapeptolides 988
Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).Fórmula:C50H68N8O13Forma y color:SolidPeso molecular:989.12Cepeginterferon alfa-2b
CAS:<p>Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.</p>Forma y color:LiquidSofigatran
CAS:Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.Fórmula:C24H44N4O4SForma y color:SolidPeso molecular:484.7N-CBZ-Phe-Arg-AMC
CAS:Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Fórmula:C33H36N6O6Pureza:98%Forma y color:White To Off-White PowderPeso molecular:612.68CRA-2059 TFA
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Forma y color:SolidDPP8/9-IN-1
<p>DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.</p>Forma y color:Odour SolidC-telopeptide
CAS:C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.Fórmula:C34H56N14O13Pureza:98%Forma y color:SolidPeso molecular:868.9CRA-2059 hydrochloride
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Forma y color:SolidLeptosin D
CAS:Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)Fórmula:C25H24N4O3S2Forma y color:SolidPeso molecular:492.61NIM811
CAS:NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Fórmula:C62H111N11O12Pureza:98%Forma y color:SolidPeso molecular:1202.635Enzyme-IN-1
CAS:Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。Fórmula:C36H50N4O7Forma y color:SolidPeso molecular:650.8Fotagliptin
CAS:Fotagliptin is a dipeptidyl peptidase IV inhibitor.Fórmula:C17H19FN6OForma y color:SolidPeso molecular:342.37AP-C2
CAS:AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.Fórmula:C18H16N4SPureza:99.99%Forma y color:SoildPeso molecular:320.41Ac-DEMEEC-OH
CAS:Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.Fórmula:C29H44N6O16S2Forma y color:SolidPeso molecular:796.82L 659286
CAS:L 659286 is one kind of cephalosporin derivative.Fórmula:C17H21N5O7S2Forma y color:SolidPeso molecular:471.51HCV-IN-4
CAS:HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.Fórmula:C52H58FN9O8Pureza:98%Forma y color:SolidPeso molecular:956.07Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Fórmula:C15H19NO3Forma y color:SolidPeso molecular:261.32
