Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(35 productos)
- Cisteína proteasa(110 productos)
- DPP-4(20 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(501 productos)
- PAI-1(25 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(95 productos)
- Serina proteasa(56 productos)
- p97(15 productos)
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Se han encontrado 1092 productos de "Proteasas / Proteasoma"
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BAY 1217224
CAS:<p>BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.</p>Fórmula:C24H27ClFN3O5Forma y color:SolidPeso molecular:491.94Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFórmula:C47H64N14O10Forma y color:SolidPeso molecular:985.1Sadopeptins B
Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].Fórmula:C48H69N9O13SForma y color:SolidPeso molecular:1012.18Dutogliptin
CAS:Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Fórmula:C10H20BN3O3Pureza:98%Forma y color:SolidPeso molecular:241.10Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Fórmula:C15H19NO3Forma y color:SolidPeso molecular:261.32PSI-7409
CAS:<p>PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).</p>Fórmula:C10H16FN2O14P3Pureza:98%Forma y color:SolidPeso molecular:500.16HCVP-IN-1
CAS:HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.Fórmula:C30H34FN5O3Forma y color:SolidPeso molecular:531.632Acetyl-Calpastatin(184-210)(human) TFA
Acetyl-Calpastatin(184-210)(human) TFA inhibits μ-calpain (Ki 0.2 nM) and cathepsin L (Ki 6 μM) selectively and reversibly.Fórmula:C144H231F3N36O46SForma y color:SolidPeso molecular:3291.65Phaeosphaone D
CAS:Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).Fórmula:C20H27N3O3S2Forma y color:SolidPeso molecular:421.58Acetyl-Calpastatin(184-210)(human)
CAS:Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.Fórmula:C142H230N36O44SPureza:98%Forma y color:SolidPeso molecular:3177.65AP-C2
CAS:AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.Fórmula:C18H16N4SPureza:99.99%Forma y color:SoildPeso molecular:320.41Ac-DEMEEC-OH
CAS:Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.Fórmula:C29H44N6O16S2Forma y color:SolidPeso molecular:796.82C-telopeptide
CAS:C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.Fórmula:C34H56N14O13Pureza:98%Forma y color:SolidPeso molecular:868.9GSK2818713
CAS:GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.Fórmula:C46H56N8O8Forma y color:SolidPeso molecular:849.002RJS308
<p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>Fórmula:C63H75N13O11SForma y color:SolidPeso molecular:1222.42APC-6860
CAS:APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.Fórmula:C9H7IN2SForma y color:SolidPeso molecular:302.13Calpain Inhibitor-1
CAS:Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.Fórmula:C19H17FN6O5SForma y color:SolidPeso molecular:460.44MK-6169
CAS:MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.Fórmula:C54H62FN9O8SPureza:98%Forma y color:SolidPeso molecular:1016.2Histatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFórmula:C135H196F3N51O35Pureza:98%Forma y color:SolidPeso molecular:3150.32NIM811
CAS:NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Fórmula:C62H111N11O12Pureza:98%Forma y color:SolidPeso molecular:1202.635
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