Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1499 productos de "Autofagia"
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Sorafenib tosylate
CAS:Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:99.24% - 99.94%Forma y color:White To Off-White Crystalline PowderPeso molecular:637.03Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Fórmula:C17H17ClF6N2OPureza:99% - 99.99%Forma y color:Off-White To Yellow SolidPeso molecular:414.77Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Forma y color:Crystals From Ether (Ntp 1992)Peso molecular:392.46Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Fórmula:C10H16ClN5Pureza:97.11% - 99.80%Forma y color:Lactic AcidosisPeso molecular:241.72Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Fórmula:C23H34O5Pureza:99.12%Forma y color:White-Yellowish To Yellow Powder Solid PowderPeso molecular:390.51Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Fórmula:C9H13N3O5Pureza:99.83% - 99.93%Forma y color:Fine Off-White Crystalline PowderPeso molecular:243.22Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Fórmula:CH4N2O2Pureza:99.85% - 99.92%Forma y color:SolidPeso molecular:76.05Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Forma y color:SolidPeso molecular:494.00Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Forma y color:Yellow SolidPeso molecular:925.46Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Forma y color:Light Yellow Solid PowderPeso molecular:433.45Thalidomide
CAS:Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.Fórmula:C13H10N2O4Pureza:98.88% - 99.88%Forma y color:White SolidPeso molecular:258.23Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Forma y color:White To Off-White PowderPeso molecular:393.44Doxazosin mesylate
CAS:Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.Fórmula:C24H29N5O8SPureza:99.92%Forma y color:White To Off-White Crystalline PowderPeso molecular:547.58Sophocarpine monohydrate
CAS:Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Fórmula:C15H22N2OPureza:99.55%Forma y color:SolidPeso molecular:246.35Oxaliplatin
CAS:Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.Fórmula:C8H14N2O4PtPureza:97% - 99.93%Forma y color:SolidPeso molecular:397.29Sunitinib Malate
CAS:Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Fórmula:C26H33FN4O7Pureza:98% - 99.26%Forma y color:SolidPeso molecular:532.56Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFórmula:C25H35N7O9S4Pureza:99.63%Forma y color:SolidPeso molecular:705.85TTNPB
CAS:TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),Fórmula:C24H28O2Pureza:99.55%Forma y color:White SolidPeso molecular:348.48Ref: TM-T1288
2mg39,00€5mg57,00€10mg87,00€25mg159,00€50mg264,00€100mg445,00€500mg1.008,00€1mL*10mM (DMSO)59,00€Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Fórmula:C14H24Cl2N2O3Pureza:99.58%Forma y color:Crystalline SolidPeso molecular:339.258Vitamin B3-d4
CAS:Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.
Fórmula:C6HD4NO2Pureza:99.86%Forma y color:SolidPeso molecular:127.13
