mTOR
Los inhibidores de mTOR son compuestos que inhiben la actividad de la Proteína diana de la rapamicina en mamíferos (mTOR), un regulador central del crecimiento celular, la proliferación, el metabolismo y la supervivencia. La vía de mTOR se altera con frecuencia en el cáncer y otras enfermedades, lo que convierte a mTOR en un objetivo crítico para la intervención terapéutica. Los inhibidores de mTOR se utilizan ampliamente en la investigación relacionada con el cáncer, el envejecimiento y los trastornos metabólicos. En CymitQuimica, ofrecemos una variedad de inhibidores de mTOR para apoyar su investigación en transducción de señales, oncología y desarrollo terapéutico.
Se han encontrado 144 productos de "mTOR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ICSN3250 HCl
CAS:<p>ICSN3250 HCl is an mTOR inhibitor that specifically targets cancer cells, preventing mTOR activation and leading to cytotoxicity.</p>Fórmula:C31H41ClN4O8Pureza:98.46% - 99.60%Forma y color:SoildPeso molecular:633.13MT 63-78
CAS:<p>MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).</p>Fórmula:C21H14N2O2Pureza:97.11%Forma y color:SolidPeso molecular:326.35NV-5138
CAS:<p>NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.Cost-effective and quality-assured.</p>Fórmula:C7H13F2NO2Pureza:98% - ≥98%Forma y color:SolidPeso molecular:181.18NSC781406
CAS:<p>NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).</p>Fórmula:C29H27F2N5O5S2Pureza:99.58%Forma y color:SolidPeso molecular:627.68SN32976
CAS:<p>SN32976 is a pan PI3K inhibitor. SN32976 potently inhibited PI3K isoforms and mTOR, displaying preferential activity for PI3Kα and sparing of PI3Kδ.</p>Fórmula:C24H33F2N9O4SPureza:98.06%Forma y color:SolidPeso molecular:581.64Rapamycin
CAS:<p>Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.</p>Fórmula:C51H79NO13Pureza:97.08% - 99.80%Forma y color:Yellow SolidPeso molecular:914.17Thioridazine hydrochloride
CAS:<p>Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4</p>Fórmula:C21H27ClN2S2Pureza:99.55% - 99.957%Forma y color:White To Off-White SolidPeso molecular:407.04FDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Forma y color:LiquidmTOR inhibitor-14
<p>mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1</p>Pureza:98%Forma y color:Odour SolidKinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Forma y color:Odour SolidQL-IX-55
CAS:<p>QL-IX-55 has a wide range of applications in life science related research.</p>Fórmula:C24H14F4N4OForma y color:SolidPeso molecular:450.39Aschantin
CAS:<p>Aschantin is a useful organic compound for research related to life sciences. The catalog number is T126072 and the CAS number is 13060-15-6.</p>Fórmula:C22H24O7Forma y color:SolidPeso molecular:400.427MCX 28
CAS:<p>MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.</p>Fórmula:C25H19N5O4S3Forma y color:SolidPeso molecular:549.64RMC-4627
CAS:<p>RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.</p>Fórmula:C93H141N11O23Forma y color:SolidPeso molecular:1781.17WYE-687
CAS:<p>WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).</p>Fórmula:C28H32N8O3Pureza:99.93%Forma y color:SolidPeso molecular:528.61YB-3-17
CAS:<p>YB-3-17 is a bifunctional molecule that can inhibit mTOR with an IC50 of 0.22 nM or degrade the G1 to S phase transition 1 gene (GSPT1) through the PROTAC mechanism, with a DC50 of 5 nM. It exhibits antiproliferative activity at nanomolar concentrations in various glioblastoma cell lines. Additionally, YB-3-17 shows antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon)</p>Fórmula:C38H39N11O6Forma y color:SolidPeso molecular:745.7862DII
<p>2DII is a potent and selective mTORC2 inhibitor. It specifically binds to the mSin1 PH domain, resulting in a decreased phosphorylation of AKT1.</p>Fórmula:C54H76ClN7O11SForma y color:SolidPeso molecular:1066.74PI3K-AKT-mTOR Compound Library
<p>A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with</p>Forma y color:Odour SolidMKC-1
CAS:<p>MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.</p>Fórmula:C22H16N4O4Pureza:99.63% - 99.85%Forma y color:SolidPeso molecular:400.39PI3K-IN-22
CAS:<p>PI3K-IN-22 is a dual kinase inhibitor of PI3Kα and mTOR, with IC50s of 0.9 and 0.6 nM respectively. PI3K-IN-22 could be used in cancer.</p>Fórmula:C31H35F3N8O3Forma y color:SolidPeso molecular:624.66RMC-4529
CAS:<p>RMC-4529 is a chemical compound that demonstrates potent inhibition, with an IC50 value of 1.0 nM, against p-4E-BP1-(T37/46) in mTOR kinase cellular assays.</p>Fórmula:C90H139N13O23Forma y color:SolidPeso molecular:1771.17mTOR inhibitor WYE-28
CAS:<p>Compound 28 (mTOR inhibitor WYE-28) is a selective inhibitor of mTOR (IC50=0.08 nM). Also inhibits PI3Kα (IC50 6 nM).</p>Fórmula:C30H34N8O5Forma y color:SolidPeso molecular:586.653mTOR inhibitor-12
<p>mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is utilized in research pertaining to central</p>Fórmula:C19H24N6O2SPureza:98%Forma y color:SolidPeso molecular:400.5PF-06465603
CAS:<p>PF-06465603 is a metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.</p>Fórmula:C22H25N5O5Forma y color:SolidPeso molecular:439.46(32-Carbonyl)-RMC-5552
CAS:<p>(32-Carbonyl)-RMC-5552, a potent mTOR inhibitor, blocks mTORC1/C2, with pIC50 values >9 for p-P70S6K and p-4E-BP1, and 8~9 for p-AKT1/2/3.</p>Fórmula:C93H134N10O24Forma y color:SolidPeso molecular:1776.141RMC-6272
CAS:<p>RMC-6272 (RM-006) is a bi-steric mTORC1 inhibitor with selective potency over mTORC2 and shows greater effects than Rapamycin on TSC2-deficient tumors.</p>Fórmula:C95H141FN6O27SForma y color:SolidPeso molecular:1850.25Anti-Phospho-MTOR (Ser2448) Antibody (2K503)
<p>Anti-Phospho-MTOR (Ser2448) Antibody (2K503) is an antibody targeting Phospho-MTOR (Ser2448). Anti-Phospho-MTOR (Ser2448) Antibody (2K503) can be used in ELISA, WB, IHC, IF.</p>Forma y color:Odour LiquidRMC-5552
CAS:<p>RMC-5552 selectively inhibits mTORC1 with ~40-fold selectivity over mTORC2, demonstrating anticancer activity and research utility.</p>Fórmula:C93H136N10O24Forma y color:SolidPeso molecular:1778.16S6K1-IN-DG2
CAS:<p>S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.</p>Fórmula:C16H17BrN6OPureza:99.25%Forma y color:SolidPeso molecular:389.25Anti-Phospho-mTOR (Ser2481) Antibody (4R8)
<p>Anti-Phospho-MTOR (Ser2481) Antibody (4R8) is an antibody targeting Phospho-MTOR (Ser2481). Anti-Phospho-MTOR (Ser2481) Antibody (4R8) can be used in ELISA, WB, IF.</p>Forma y color:Odour LiquidCbz-B3A
CAS:<p>Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.</p>Fórmula:C35H58N6O9Pureza:98.59%Forma y color:SolidPeso molecular:706.873BDO
CAS:<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Fórmula:C18H17NO5Pureza:97.76%Forma y color:SolidPeso molecular:327.33Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Forma y color:SolidPeso molecular:432.4Lupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Fórmula:C20H18O5Pureza:98.92%Forma y color:SolidPeso molecular:338.35PI-103
CAS:<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Fórmula:C19H16N4O3Pureza:97.79% - 99.3%Forma y color:SolidPeso molecular:348.36WYE-354
CAS:<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Fórmula:C24H29N7O5Pureza:97.86% - 99.61%Forma y color:SolidPeso molecular:495.53Bimiralisib
CAS:<p>Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.</p>Fórmula:C17H20F3N7O2Pureza:97.58% - 98.92%Forma y color:SolidPeso molecular:411.38Omipalisib
CAS:<p>Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.</p>Fórmula:C25H17F2N5O3SPureza:98% - 99.8%Forma y color:SolidPeso molecular:505.5BGT226
CAS:<p>BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.</p>Fórmula:C28H25F3N6O2Pureza:95.74% - 99.51%Forma y color:SolidPeso molecular:534.53XL388
CAS:<p>XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.</p>Fórmula:C23H22FN3O4SPureza:99.39% - 99.53%Forma y color:SolidPeso molecular:455.5GNE-493
CAS:<p>GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for</p>Fórmula:C17H20N6O2SPureza:98%Forma y color:SolidPeso molecular:372.44Cyclovirobuxine D
CAS:<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Fórmula:C26H46N2OPureza:97.78% - 98%Forma y color:SolidPeso molecular:402.66OSI-027
CAS:<p>OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.</p>Fórmula:C21H22N6O3Pureza:97.42%Forma y color:SolidPeso molecular:406.44PF-04691502
CAS:<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Fórmula:C22H27N5O4Pureza:96.27% - ≥95%Forma y color:SolidPeso molecular:425.48Samotolisib
CAS:<p>Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.</p>Fórmula:C23H26N4O3Pureza:98.41% - 99.69%Forma y color:SolidPeso molecular:406.48D-α-Hydroxyglutaric acid disodium
CAS:<p>D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.</p>Fórmula:C5H6Na2O5Pureza:97.16%Forma y color:SolidPeso molecular:192.08mTOR inhibitor-1
CAS:<p>C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.</p>Fórmula:C16H15BrN2O3Pureza:99.43%Forma y color:SolidPeso molecular:363.21Autogramin-1
CAS:<p>Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.</p>Fórmula:C23H27N5O5SPureza:97.69% - 99.25%Forma y color:SolidPeso molecular:485.56GNE-477
CAS:<p>GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.</p>Fórmula:C21H28N8O3S2Pureza:98.88% - 99.55%Forma y color:SolidPeso molecular:504.63Salidroside
CAS:<p>Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C14H20O7Pureza:97.81%Forma y color:Red-Brown Fine PowderPeso molecular:300.3Corynoxine
CAS:<p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>Fórmula:C22H28N2O4Pureza:96.83% - 99.93%Forma y color:SolidPeso molecular:384.47Mito-LND
CAS:<p>Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.</p>Fórmula:C43H45BrCl2N3OPPureza:97.25% - 98.34%Forma y color:SolidPeso molecular:801.62GNE-317
CAS:<p>GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).</p>Fórmula:C19H22N6O3SPureza:98.42% - 99.54%Forma y color:SolidPeso molecular:414.48Everolimus
CAS:<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Fórmula:C53H83NO14Pureza:97.76% - 99.78%Forma y color:Off-White To Light Yellow PowdPeso molecular:958.2225(R,S)-Ruscogenin
CAS:<p>25(R,S)-Ruscogenin is able to regulate the PI3K/Akt/mTOR signalling pathway, and hinder the metastasis of hepatocellular carcinoma.</p>Fórmula:C27H42O4Pureza:99.32% - 99.89%Forma y color:SolidPeso molecular:430.62AZD-8055
CAS:<p>AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.</p>Fórmula:C25H31N5O4Pureza:98% - 99.69%Forma y color:SolidPeso molecular:465.54NV-5138 hydrochloride
<p>NV-5138 hydrochloride: a leucine analog, oral brain mTORC1 activator via Sestrin2, for antidepressant research.</p>Fórmula:C7H14ClF2NO2Forma y color:SolidPeso molecular:217.64Palomid 529
CAS:<p>Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.</p>Fórmula:C24H22O6Pureza:98.40% - 98.59%Forma y color:SolidPeso molecular:406.43KU-0063794
CAS:<p>KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.</p>Fórmula:C25H31N5O4Pureza:98.21% - >99.99%Forma y color:SolidPeso molecular:465.54WYE-687 dihydrochloride
CAS:<p>WYE-687 dihydrochloride is an mTOR inhibitor with IC50 of 7 nM, also targeting PI3Kα (81 nM) and PI3Kγ (3.11 μM).</p>Fórmula:C28H34Cl2N8O3Forma y color:SolidPeso molecular:601.53SC99
CAS:<p>SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.</p>Fórmula:C15H8Cl2FN3OPureza:99.56%Forma y color:SolidPeso molecular:336.15L-Leucine
CAS:<p>L-Leucine is an essential amino acid vital for protein synthesis, metabolism, muscle and bone repair, blood sugar control, and wound healing.</p>Fórmula:C6H13NO2Pureza:99.83%Forma y color:White Solid CrystallinePeso molecular:131.17Vistusertib
CAS:<p>Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.</p>Fórmula:C25H30N6O3Pureza:97.08% - 99.06%Forma y color:SolidPeso molecular:462.54Onatasertib
CAS:<p>Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.</p>Fórmula:C21H27N5O3Pureza:99.14% - 99.97%Forma y color:SolidPeso molecular:397.47Voxtalisib
CAS:<p>Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.</p>Fórmula:C13H14N6OPureza:98.21% - 99.69%Forma y color:SolidPeso molecular:270.29PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Fórmula:C17H17N7Pureza:98.45% - 99.67%Forma y color:SolidPeso molecular:319.36Polyphyllin I
CAS:<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Fórmula:C44H70O16Pureza:98% - 99.5%Forma y color:SolidPeso molecular:855.02Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Forma y color:SolidPeso molecular:607.62G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39Apitolisib
CAS:<p>Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).</p>Fórmula:C23H30N8O3SPureza:98.28% - 99.64%Forma y color:SolidPeso molecular:498.6Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14GSK1059615
CAS:<p>GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.</p>Fórmula:C18H11N3O2SPureza:99.3% - ≥95%Forma y color:SolidPeso molecular:333.36Sapanisertib
CAS:<p>Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.</p>Fórmula:C15H15N7OPureza:99.19% - >99.99%Forma y color:SolidPeso molecular:309.33Hederacolchiside A1
CAS:<p>Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.</p>Fórmula:C47H76O16Pureza:98.76% - 99.92%Forma y color:SolidPeso molecular:897.1Arnicolide D
CAS:<p>Arnicolide D is a sesquiterpene lactone.</p>Fórmula:C19H24O5Pureza:96.66%Forma y color:SolidPeso molecular:332.39Torkinib
CAS:<p>Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).</p>Fórmula:C16H16N6OPureza:99.11%Forma y color:SolidPeso molecular:308.34Temsirolimus
CAS:<p>Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.</p>Fórmula:C56H87NO16Pureza:97.76% - >99.99%Forma y color:White Crystalline PowderPeso molecular:1030.29Rotundic acid
CAS:<p>Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.</p>Fórmula:C30H48O5Pureza:96.91% - 99.97%Forma y color:SolidPeso molecular:488.7TMBIM6 antagonist-1
CAS:<p>TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor</p>Fórmula:C15H12N2O3Pureza:99.26%Forma y color:SolidPeso molecular:268.27Zotarolimus
CAS:<p>Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).</p>Fórmula:C52H79N5O12Pureza:95% - 98.01%Forma y color:SolidPeso molecular:966.21(+)-Usnic acid
CAS:<p>(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.</p>Fórmula:C18H16O7Pureza:98.22%Forma y color:SolidPeso molecular:344.32CZ415
CAS:<p>CZ415 is a potent and highly selective mTOR inhibitor.</p>Fórmula:C22H29N5O4SPureza:97.54% - 98.36%Forma y color:SolidPeso molecular:459.56VS-5584
CAS:<p>VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.</p>Fórmula:C17H22N8OPureza:97.82% - 99.54%Forma y color:SolidPeso molecular:354.41Dihydromyricetin
CAS:<p>Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.</p>Fórmula:C15H12O8Pureza:96.68% - 98.229%Forma y color:SolidPeso molecular:320.25MHY1485
CAS:<p>MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.</p>Fórmula:C17H21N7O4Pureza:97.74% - >99.99%Forma y color:SolidPeso molecular:387.39ETP-45658
CAS:<p>ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).</p>Fórmula:C16H17N5O2Pureza:99.14%Forma y color:SolidPeso molecular:311.34Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Fórmula:C30H23N5OPureza:97.64% - 99.85%Forma y color:SolidPeso molecular:469.54PQR620
CAS:<p>PQR620 is a novel potent and selective, brain penetrant inhibitor of mTORC1/2.</p>Fórmula:C21H25F2N7O2Pureza:97.61%Forma y color:SolidPeso molecular:445.47DMH-25
CAS:<p>DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells.</p>Fórmula:C15H8Br3NO3Pureza:99.26%Forma y color:SolidPeso molecular:489.94Ridaforolimus
CAS:<p>Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。</p>Fórmula:C53H84NO14PPureza:90.00% - 98.55%Forma y color:Off-White SolidPeso molecular:990.21DIM-C-pPhOH
CAS:<p>CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.</p>Fórmula:C23H18N2OPureza:98.61%Forma y color:SolidPeso molecular:338.4CC-115
CAS:<p>CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).</p>Fórmula:C16H16N8OPureza:86.79% - 99.01%Forma y color:SolidPeso molecular:336.35PQR530
CAS:<p>PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and has antitumor properties.</p>Fórmula:C18H23F2N7O2Pureza:99.5%Forma y color:SolidPeso molecular:407.42PKCβ inhibitor 1
CAS:<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Fórmula:C24H21N5O2Pureza:99.33%Forma y color:SolidPeso molecular:411.46KU-0060648
CAS:<p>KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ.</p>Fórmula:C33H34N4O4SPureza:98.75%Forma y color:SolidPeso molecular:582.71Desmethyl-VS-5584
CAS:<p>Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.</p>Fórmula:C16H20N8OPureza:>99.99%Forma y color:SolidPeso molecular:340.38MHY-1685
CAS:<p>MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can rejuvenate senile hCSCs by modulating autophagy.</p>Fórmula:C11H8N2O4Pureza:99.76%Forma y color:SolidPeso molecular:232.19DS-7423
CAS:<p>DS-7423: a dual PI3K/mTOR inhibitor; IC50s—PI3Kα: 15.6 nM, mTOR: 34.9 nM, PI3Kβ: 1,143 nM, PI3Kγ: 249 nM, PI3Kδ: 262 nM.</p>Fórmula:C22H27F3N10O2Pureza:99.98%Forma y color:SolidPeso molecular:520.51Gedatolisib
CAS:<p>Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signaling</p>Fórmula:C32H41N9O4Pureza:98% - 99.36%Forma y color:SolidPeso molecular:615.73
