Heterociclos con nitrógeno (N)

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<p>2-Amino-3-nitropyridine is a synthetic molecule that has the chemical formula C6H7N5O2. It can exist in four different forms, three of which are isomers. These three isomers have different properties, such as melting point and solubility. The synthesis of 2-amino-3-nitropyridine can be achieved through a solid phase synthesis using sodium periodate as the acid catalyst. The reaction mechanism involves nitration of 2-amino pyridine with hydrogen peroxide to produce 3-nitro pyridine followed by hydrolysis to form 2-amino-3 nitropyridine. This reaction produces two dihedral angles in the molecule, one between the nitrogen and oxygen atoms and another between the nitrogen atom and carbon atom bonded to it. The functional groups present on this molecule are an amino group, a nitro group, and an amide group.</p>

<p>1,2,4-Triazole-3-carboxamide is a pharmacologic agent that inhibits the synthesis of polypeptides by interfering with neurotransmission. It is used to inhibit the replication of influenza virus and other viruses in tissue culture. The compound has been shown to have an inhibitory effect on viruses by binding to the viral polypeptide chain at the active site and preventing its polymerization into a functional protein. 1,2,4-Triazole-3-carboxamide also inhibits the activity of influenza virus neuraminidase (NA) by binding reversibly to the active site of NA and blocking its catalytic activity. The inhibition of NA leads to a decrease in release of virus particles from infected cells and thus prevents infection.</p>

<p>2,4,6-Tri(4-pyridyl)-1,3,5-triazine (TPTZ) is a diamagnetic molecule. It has been shown to have anticancer activity in vitro and in vivo. TPTZ is luminescent when exposed to UV light and its emission spectrum is dependent on the environment. TPTZ has been synthesized by organic solution chemistry and by transfer from inorganic materials. The organic solution synthesis involves the formation of TPTZ from an organic ligand and triazine. The transfer mechanism occurs when an azo compound reacts with an amine precursor to form an iminium salt intermediate that reacts with triazine to form TPTZ.</p>

<p>Boc-4-hydroxypiperidine-2-carboxylic acid is a high quality, reagent, and complex compound. It has CAS No. 917835-93-9 and can be used as an intermediate or building block in synthesis of other chemicals. In addition, Boc-4-hydroxypiperidine-2-carboxylic acid is a versatile building block that is used in the manufacture of speciality chemicals and research chemicals.</p>

<p>Piperonylnitrile is a chemical substance that is used as an intermediate in the production of anisidine and piperonal. It can be activated by radiation, hydrochloric acid, or chloride to form an active intermediate that can react with an aldoxime to produce a nitrile oxide. Piperonylnitrile has been shown to have an inhibitory effect on the reaction between hydrochloric acid and piperonal. Reaction time was increased from 2 hours at room temperature to 6 days when piperonylnitrile was added to the reaction mixture. Piperonylnitrile also has a dehydrating effect on low molecular weight compounds.</p>

<p>Indole-3-carboxylic acid methyl ester is a quinoline derivative that is structurally related to the well-known antibiotic, ciprofloxacin. It has been shown to be cytotoxic against a variety of bacterial strains including Pseudomonas aeruginosa and Staphylococcus aureus. The mechanism of action for this compound is not yet fully understood, but it has been shown to inhibit collagen production in cell cultures and induce neuronal death in mice. Indole-3-carboxylic acid methyl ester also possesses anti-cancer properties and inhibits fatty acid synthesis. This compound also has antifungal effects against Candida albicans and other fungi.</p>

<p>2-Amino-5-bromopyrazine-3-carboxylic acid is an organic compound that belongs to the group of boronic acids. It has a molecular weight of 138.14 and a melting point of 198°C. The compound has been characterized by x-ray crystallography, revealing its molecular structure. 2-Amino-5-bromopyrazine-3-carboxylic acid is soluble in water and can be isolated from the reaction mixture using conventional methods such as recrystallization. The compound reacts with alkyl halides through cross coupling reactions to form pyridyl compounds. This reagent is used for Suzuki, Miyaura, and other cross coupling reactions with high yield.</p>

<p>2-Quinolinecarboxylic acid is an antibiotic that is used in the treatment of bacterial infections and has inhibitory properties. It has been shown to be a competitive inhibitor of the enzyme quinolinate phosphoribosyltransferase, which catalyzes the conversion of quinolinic acid to nicotinic acid. 2-Quinolinecarboxylic acid binds to the active site of the enzyme and prevents substrate binding, thereby blocking the production of nicotinic acid. This drug also inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucur</p>

<p>2,4-Dimethyl-3-nitropyridine is a heterocyclic organic compound. It is an important and versatile building block for the synthesis of complex compounds. 2,4-Dimethyl-3-nitropyridine can be used as a reagent in organic synthesis and other chemical reactions. In addition to its use as a reactant, this compound has been employed as a useful scaffold for the preparation of other heterocycles and fine chemicals. The CAS number for 2,4-dimethyl-3-nitropyridine is 1074-76-6.</p>

<p>N-Ethylamine-2,4,6-triphenyl pyridinium tetrafluoroborate is a chemical reagent that belongs to the group of fine chemicals. It is soluble in water and ethanol, and has a melting point of around 100°C. N-Ethylamine-2,4,6-triphenyl pyridinium tetrafluoroborate is used in organic synthesis as a useful building block or as a research chemical for the production of other compounds. This compound is a versatile building block that can be used in the preparation of complex compounds such as pharmaceuticals. N-Ethylamine-2,4,6-triphenyl pyridinium tetrafluoroborate has been classified as an extremely hazardous substance by the US Department of Transportation due to its high reactivity with water.</p>

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<p>Monomethyl triazeno imidazole carboxamide (MTIC) is a drug that is used to treat cancer. It has been shown to inhibit the proliferation of tumor cells and induce apoptosis by inhibiting the expression of proteins, such as Bcl-2, which are involved in regulating mitochondrial membrane potential. MTIC has also been shown to inhibit protein synthesis and cell signaling pathways, such as the PI3K/Akt pathway. The use of MTIC for diagnosis purposes can be achieved using electrochemical impedance spectroscopy. A concentration–time curve can be obtained by incubating a biological sample with MTIC and measuring cell response using an impedance spectrophotometer. The clinical properties of MTIC include its ability to be administered orally or intravenously, have low toxicity, and inhibit the growth of tumor cells in vivo and in vitro.</p>

<p>N-Nitroso-3-azabicyclo[3.3.0]octane is a nitrosating agent that can be used for the determination of gliclazide in pharmaceuticals and other applications. It is synthesized by reacting 3-azabicyclo[3.3.0]octane with sodium nitrite in an alkaline environment, followed by hydrolysis with hydrochloric acid. Nitrosation reactions are usually slow, but N-nitroso-3-azabicyclo[3.3.0]octane has been shown to have a fast reaction kinetics, which makes it useful for the determination of gliclazide in pharmaceuticals and other applications. The product is analyzed using chromatographic techniques such as high performance liquid chromatography (HPLC) or gas chromatography/mass spectrometry (GC/MS). The product was found to be linear over the range of 0–</p>

<p>4-Vinylpyridine, stabilized with 100ppm Hydroquinone is a chemical compound that belongs to the class of pyridines. It has been shown to be stable in aqueous solution and to have a high water permeability. The reaction mechanism is not known, but it is thought that the quaternization of the vinyl group may be involved. 4-Vinylpyridine has been used as a component for the synthesis of polymers and can also be used in palladium-catalyzed coupling reactions.</p>

<p>Nd-Pyrazinylcarbonyl-L-ornithine is a versatile building block for the synthesis of complex compounds. This compound is used as a reagent for research and as a speciality chemical. It has been shown to be an intermediate in organic chemistry and as a reaction component in organic synthesis. Nd-Pyrazinylcarbonyl-L-ornithine is also useful as a scaffold in drug development, with its applications including antiviral agents, antibiotics, anticancer drugs, and antifungal drugs.</p>

<p>Dodecylpyridinium bromide is a glycol ether surfactant that is used as an inhibitor molecule. It inhibits multidrug efflux pumps, which are proteins in the membrane of cells that pump drugs out of the cell. Dodecylpyridinium bromide is also used as a surfactant in water-based paints and coatings, as well as in printing ink formulations. This chemical has been shown to have amoebicidal activity by interacting with the phospholipids on the surface of the amoeba, causing it to go into spore formation. Dodecylpyridinium bromide is also used for its ability to inhibit the growth of bacteria such as Staphylococcus epidermidis and Pseudomonas aeruginosa, which can cause infection in burn patients.<br>Dodecylpyridinium bromide can be synthesized from benzalkon</p>

<p>2-Ethoxy-5-nitropyridine is a potassium salt of 2-ethoxy-5-nitropyridine. It has been used as a reagent in the synthesis of sulfonates, pyridines, and phenols. The nitrogen atom in this molecule can be oxidized to nitro group. This compound also reacts with anilines to form 2-chloro-5-nitropyridine and 2-hydroxy-5-nitropyridine. In addition, it can react with halogen to form substituted anilines or chloropyridines. 2-Ethoxy-5-nitropyridine is a nucleophile that can be used for the preparation of nucleophiles for biomolecular chemistry studies.</p>

<p>(2R)-1-(Phenylmethyl)-N-[3-(spiro[isobenzofuran-1(3H),4'-piperidin]-1-yl)propyl-2-pyrrolidinecarboxamide HCl is an endogenous opioid that has been shown to have antidepressant-like effects. It can bind to γ-aminobutyric acid (GABA) receptors, catecholamine receptors, and nociceptin receptors. This drug also has anti-cancer properties and may be used for the treatment of autoimmune diseases. The interaction of this drug with other drugs is not well understood, but it has been shown to modulate the effects of opioids and increase the aversive nature of some substances.</p>

<p>7-Azaindole is a reactive chemical that has been shown to be effective in the treatment of skin cancer, as well as hepatic steatosis. The compound can promote the transfer of hydrogen atoms and form a dimer with protonated nitrogen. 7-Azaindole reacts rapidly with nucleophiles such as amines, alcohols, and thiols to form covalent bonds. The reaction mechanism is characterized by an initial protonation step followed by nucleophilic attack or hydrogen transfer from the nucleophile to 7-azaindole. Kinetic studies have demonstrated that the rate of this reaction depends on the concentration of both reactants.</p>

<p>Succinimidyl 3-(bromoacetamido)propionate (SBAP) is a reactive chemical that can be used to synthesize a variety of polymers. SBAP is used in the treatment of inflammatory bowel disease, where it acts as an immunosuppressant by suppressing antibody response to the bowel. SBAP has also been shown to increase collagen production and glycoconjugates, which are compounds found on the surface of cells that act as receptors for many types of bacteria and viruses. The polymerase chain reaction (PCR), which is used in DNA analysis, uses SBAP as a way to separate DNA fragments. For this reason, SBAP is often found in wastewater treatment plants. It has been shown that exposure to SBAP can cause infectious diseases in humans, such as tuberculosis and leprosy. This compound has also been studied for its effects on growth factor-β1 and body mass index, which may help with autoimmune diseases such as multiple</p>

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<p>5-Bromo-6-chloropyrazin-2-amine is a high quality, versatile building block for the synthesis of a variety of chemical compounds. It is also a reagent used in organic chemistry for the conversion of alcohols to alkyl chlorides and bromides. It can be used as an intermediate for the preparation of various complex compounds with potential use as pharmaceuticals or fine chemicals. This compound has been shown to have potential as a useful scaffold for the development of novel drugs which could be used to treat bacterial infections such as tuberculosis. 5-Bromo-6-chloropyrazin-2-amine has also been shown to be an excellent starting material for the synthesis of research chemicals and speciality chemicals.</p>

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<p>4,4' -Bis(N,N-dimethylamino)-2,2' -bipyridine (DMAB) is a ligand that is used in electrochemical studies. It has been shown to have ancillary properties, which means that it does not interact directly with the substrate but modifies its environment. DMAB can form a complex with the proton at the electrode surface and x-ray crystal structures have been obtained for this interaction. These structures demonstrate that DMAB binds to the tetrazole ring of pyridine and stabilizes the molecule by increasing its redox potentials.</p>

<p>(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.</p>

<p>2-Bromo-4-iodopyridine is a coordination compound that inhibits bacterial enzyme catechol-O-methyltransferase (COMT). It is also an inhibitor of methicillin-resistant Staphylococcus aureus (MRSA) and other bacteria. 2-Bromo-4-iodopyridine binds to the active site of COMT, which is located in the bacterial cell wall, and prevents methylamine from binding to the enzyme. This prevents methylation of the catechol ring, which is required for bacterial growth. 2-Bromo-4-iodopyridine has been shown to have antimicrobial activity against Escherichia coli, Enterococcus faecalis, Bacillus subtilis, and Candida albicans.</p>

<p>N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is a high quality reagent that can be used as an intermediate for the synthesis of complex organic compounds. It is a complex compound that contains boronic acid and bipyridinium moieties. N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is useful in the synthesis of fine chemicals and speciality chemicals. It has versatile building block properties and can be used as a reaction component in many chemical reactions.</p>

<p>2-(Pyridin-2-ylthio)ethyl]amine dihydrochloride is a chemical compound that has been used as a research reagent. It reacts with other compounds to produce new substances, and it can be used as a building block for more complex compounds. 2-(Pyridin-2-ylthio)ethyl]amine dihydrochloride is soluble in water and organic solvents such as acetone and ethanol, making it useful for reactions that require both types of solvents. This product also has CAS No. 40379-31-5, which means it is listed on the Chemical Abstracts Service registry. 2-(Pyridin-2-ylthio)ethyl]amine dihydrochloride has an interesting chemical structure that makes it a versatile building block or intermediate for many different reactions.</p>

<p>2-Amino-3-chloropyrazine is an active analogue of pyrazinamide, which is a potent antimycobacterial drug. It has been shown to have bacteriostatic activity against Mycobacterium tuberculosis in vitro and in vivo. 2-Amino-3-chloropyrazine has been shown to inhibit mitochondrial membrane potential, which may be due to its ability to inhibit hepg2 cell growth by decreasing intracellular ATP levels. It also inhibits the synthesis of bacterial DNA and protein, thereby inhibiting bacterial growth. 2-Amino-3-chloropyrazine has also been shown to have antitumor properties against mouse tumor cells. The pharmacokinetic properties of this drug are not well understood yet, but it has been shown that it can be detected in serum after administration</p>

<p>1-Pyrazin-2-ylpiperidin-4-amine dihydrochloride is a fine chemical that is used as an intermediate for the synthesis of research chemicals, speciality chemicals and other complex compounds. This compound has been shown to be useful in the synthesis of a variety of building blocks, including pharmaceuticals and agrochemicals. It can be used in reactions with a wide range of reagents and catalysts, which makes it an excellent starting point for new product development.</p>

<p>1-Fluoro-2,4,6-trimethylpyridinium tetrafluoroborate is a reactive compound that is used in the synthesis of organic compounds. It can be used as a precursor to introduce fluorine into organic molecules. This reagent may also be used in reductive eliminations and dehydrogenative coupling reactions. 1-Fluoro-2,4,6-trimethylpyridinium tetrafluoroborate is thermodynamically stable and can be stored at room temperature for long periods of time.</p>

<p>2-Chloro-6-(trichloromethyl)pyridine (2CTCP) is an inorganic acid that is used as a synthetic reagent in the synthesis of pharmaceuticals, such as antihistamines, vasodilators and antipsychotics. 2CTCP inhibits the process of nitrification by competing with nitrite for the enzyme nitrate reductase. It also inhibits plant metabolism by inhibiting nitrogen fixation and hydrogen production. 2CTCP is not toxic to humans or animals under normal conditions; however, it may be hazardous if inhaled or ingested. 2CTCP can be synthesized by reacting sodium carbonate with chloroacetyl chloride followed by hydrolysis of the resulting intermediate. The analytical method for 2CTCP involves gas chromatography with electron capture detection (GC-ECD). The compound can also be analyzed using high performance liquid chromatography (HPLC).</p>

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<p>4-Acetoxyindole is a chromophore that belongs to the pyrrole family of compounds. It has been shown to react with an ionic liquid under acidic conditions to form a protonated intermediate, which can be deprotonated by a nucleophile. This reaction yields an acetate anion and a fluorescing product. 4-Acetoxyindole also reacts with deuterium gas, yielding an acetate, a deuterium atom, and fluorescing product. The reaction is reversible and the yield of the product depends on the concentration of the reactants. 4-Acetoxyindole has strong carbonyl groups that make it reactive towards other functional groups. These reactions are useful for synthesizing heterocycles such as indoles and isoquinolines.</p>

<p>4-Bromopyrimidine hydrobromide is a synthetic analog of phenylpyrimidine. It has been shown in vivo to lower the blood glucose levels of diabetic patients by inhibiting the activity of phosphoenolpyruvate carboxykinase, which is involved in the conversion of glucose to pyruvate. 4-Bromopyrimidine hydrobromide also inhibits the synthesis of glycogen and lowers serum triglycerides in both db/db mice and normal mice. The drug has not been evaluated for its effects on other metabolic parameters such as cholesterol or insulin resistance. 4-Bromopyrimidine hydrobromide may have potential as an anti-obesity drug because it reduces food intake and weight gain in db/db mice.</p>

<p>4-Imidazoleacetic acid HCl is a fluorescent probe that binds to the α1 subunit of the dinucleotide phosphate (NADH) oxidoreductase. It has been shown to inhibit mitochondrial functions, which may be due to its ability to inhibit the pentose phosphate pathway and reduce reactive oxygen species levels. 4-Imidazoleacetic acid HCl has also shown inhibitory properties against congestive heart failure by acting on the mitochondria and inhibiting energy metabolism. It can also be used as a chemical biology tool for studying protein interactions with NADH dehydrogenase. The x-ray crystal structures have revealed that 4-imidazoleacetic acid HCl binds to the active site of NADH oxidoreductase with an orientation that mimics a substrate molecule. This allows it to bind tightly and disrupt enzyme activity.</p>

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<p>1-Boc-4-methylpiperazine is an inhibitor of the enzyme hydrolase. It has been shown to have a dose-dependent effect on inflammatory pain and can be used for the treatment of neuropathic pain. 1-Boc-4-methylpiperazine also has potent inhibitory activity against fatty acid amide hydrolase (FAAH) and fatty acid amide hydrolase (FAAH). It is orally administered and has been shown to have analgesic effects in animal studies. 1-Boc-4-methylpiperazine also inhibits the enzymatic activity of other hydrolases, such as cyclooxygenase 2 (COX2) and acetylcholinesterase (AChE), which are involved in inflammation, pain, and memory.</p>

<p>5-Ethylindole-2-carboxylic acid is an organic compound that is a decarboxylation product of indole. It can be obtained by catalytic dehydrogenation of ethyl ester or 5-ethylindole-2-carboxylic acid. It has been shown to inhibit the growth of bacteria and fungi, as well as to have anti-inflammatory properties.</p>

<p>This polymer is a high efficiency, low cost particle that can be used to store electricity at temperatures of up to 300 degrees Celsius. It has a cycle life of more than 10,000 cycles and can be recharged in less than one minute. This polymer has been shown to have excellent structural stability and structural reversibility with lithium ion insertion/extraction. The coulombic efficiency is greater than 99%.</p>

<p>Azide-activated cleavable biotin probe</p>

<p>Indole-3-carboxaldehyde is a chemical compound that is used as an antimicrobial agent. The biological properties of this compound are not well studied, but it has been shown to be effective against bacteria and fungi. Indole-3-carboxaldehyde has been shown to inhibit the enzyme activity of sodium carbonate, which is involved in the production of lactic acid in bacteria. This effect may contribute to its antibacterial activity. Indole-3-carboxaldehyde is also a potential anticancer agent because it can bind to toll-like receptor 4 (TLR4). Indole-3-carboxaldehyde reacts with sulfa drugs through a mechanism similar to the reaction between hydrogen peroxide and potassium permanganate. It has been shown that indole-3-carboxaldehyde can be used as a pesticide for plants and as an electrochemical impedance spectroscopy probe for histological analysis.</p>

<p>1-Phenyl-piperidine is a psychoactive compound that has been shown to have strong binding affinity for the κ-opioid receptors. It has also been shown to increase locomotor activity in mice and produce hallucinations. 1-Phenyl-piperidine has a number of biological properties including inhibition of dopamine uptake, induction of myocardial infarcts, and toxicity to the ischemic brain. It binds with high affinity to the multidrug efflux pumps such as P-glycoprotein (Pgp) and MDR1, which are responsible for removing drugs from cells. Pgp is induced by cytochrome P450 3A4 (CYP3A4) inhibitors such as ketoconazole, erythromycin, fluconazole, itraconazole, clarithromycin, telithromycin, nefazodone, and grapefruit juice.</p>

<p>5-Methylpyridin-2-yl)methanamine is a high quality reagent that is used as a building block in the synthesis of complex compounds. It can be used as an intermediate, useful for the preparation of fine chemicals and useful scaffolds. It can also be used as a speciality chemical and is often used as a reaction component in research chemicals.</p>

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<p>1-Propyl-3-piperidone hydrochloride hydrate is a high quality chemical that can be used as a reagent in organic synthesis. It is an intermediate for the production of pharmaceuticals, agrochemicals, and other chemicals. 1-Propyl-3-piperidone hydrochloride hydrate is also a versatile building block with many uses as a reaction component. This compound has been shown to have antiulcer properties and may also have potential as an analgesic.</p>

<p>4-Methyl-6-chloropyrimidine is an intermediate in the synthesis of 6-chloropurine, which is a dihydrochloride salt that can be hydrolyzed to form tetrapeptides. The nature of the reaction conditions employed for this conversion determines the yield of 4-methyl-6-chloropyrimidine. It can be synthesized by alkaline hydrolysis or by condensation of n-terminal amino acids with chloroacetic acid derivatives. This compound can also undergo hydrolytic cleavage to form oligopeptides and glycinates, which are n-substituted with dicyclohexylcarbodiimide.</p>

<p>3-(Trifluoromethyl)pyridine-2-sulfonamide is a fine chemical used in the synthesis of complex compounds, research chemicals, and reagents. It is also a useful building block for the synthesis of valuable chemical products such as pharmaceuticals, agrochemicals, and high-tech materials. 3-(Trifluoromethyl)pyridine-2-sulfonamide has been classified by the US Chemical Abstract Service (CAS) Number 104040-76-8. This product is available in bulk quantities that are both high quality and pure.</p>

<p>6-Aminoquinolyl-N-hydroxysuccinimidylcarbamate reacts rapidly with amino acids to form stable urea derivatives. The use of fluorescence detection techniques allows quantification of amines at pmol levels. 6-Aminoquinolyl-N-hydroxysuccinimidylcarbamate was used in a study to derivatize glycated amino acids with the purpose of developing chromatographic assays for their quantification. Glycation of proteins initially gives rise to early glycation adducts, then progresses to advanced glycation end-products, which are markers for conditions such as diabetes, cataracts, uraemia and Alzheimer's disease. We also offer the product FA36291.</p>

<p>2-Piperazin-1-ylacetamide hydrochloride is a drug that binds to the protein PCSK9, which transports cholesterol into cells. It blocks the transport of cholesterol and therefore lowers the level of cholesterol in blood. 2-Piperazin-1-ylacetamide hydrochloride is used for the treatment of bowel disease, atrial fibrillation (a type of irregular heartbeat), congestive heart failure, and as an anti-viral agent. This drug has been shown to reduce levels of LDL cholesterol by up to 60%. 2-Piperazin-1-ylacetamide hydrochloride has also been shown to be effective against cancers such as prostate cancer and inflammatory bowel disease.</p>

<p>5-Pyridin-2-yl-2H-tetrazol-2-yl)acetic acid is a chemical compound that can be used as a research chemical, reagent, or speciality chemical in the synthesis of pharmaceuticals, pesticides, and other organic compounds. It is also an intermediate for the production of other compounds and has been shown to have antioxidant properties. 5-(pyridin-2-yl)-2H tetrazole is a useful building block in the synthesis of complex compounds and scaffolds.</p>

<p>3-Methylpiperidin-3-ol is a chemical compound that has been found to be useful as a building block for the synthesis of various complex compounds. This product is used in research and as a reagent. 3-Methylpiperidin-3-ol is also known by the CAS number 473730-88-0.</p>

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<p>6-Hydrazino-3-pyridinecarboxylic acid is a potent inhibitor of angiogenesis. It inhibits the activity of vascular endothelial growth factor, which is a potent pro-angiogenic factor. 6HPCA has been shown to inhibit the growth of prostate cancer cells in vitro and tumor growth in vivo. The mechanism for this inhibition may be due to its ability to decrease levels of all-trans retinoic acid (RA), a potent pro-angiogenic molecule. 6HPCA also inhibits the proliferation of human serum, monoclonal antibody, and polymer drug uptake in cell culture systems. In addition, 6HPCA has low toxicity and low pharmacokinetic properties that have been demonstrated by several studies using radiolabeled analogues and autoradiography.</p>

<p>Tetraethyl 2,2'-bipyridine-4,4'-diylbisphosphonate is a chemical that is used as an intermediate in the synthesis of other fine chemicals. Tetraethyl 2,2'-bipyridine-4,4'-diylbisphosphonate can be used as a building block for synthesis of more complex compounds with high chemical and biological activity. Tetraethyl 2,2'-bipyridine-4,4'-diylbisphosphonate can also be used to synthesize speciality chemicals or research chemicals. This compound has many versatile uses due to its ability to react with different substances to form new chemical compounds.</p>

<p>2-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one (ITZ) is an antifungal drug that inhibits the synthesis of ergosterol. It is used in the treatment of systemic fungal infections such as candidiasis and cryptococcosis. ITZ is a metabolite of itraconazole and fluconazole. The presence of impurities in ITZ can be detected by liquid chromatography with a diode array detector or a fluorescence detector. An antiinfective drug product should be bioequivalent to the reference product and have comparable levels of impurities. Chromatograms are used to identify peaks on a graph and measure their height (area under the curve) to determine how much of each substance is present in the sample.</p>

<p>N-Benzyl-4-phenyl pyridinium tetrafluoroborate is a fine chemical that can be used as a building block in the synthesis of complex compounds. It has been shown to have versatile applications in organic synthesis, such as being a useful intermediate and reaction component. N-Benzyl-4-phenyl pyridinium tetrafluoroborate is an extremely high quality reagent with few side effects and low toxicity.</p>

<p>1-Methylindole is a chemical compound that belongs to the group of pyrimidine compounds. It has been shown to have antibacterial activity against many types of bacteria, including methicillin-resistant Staphylococcus aureus and Clostridium perfringens. 1-Methylindole inhibits bacterial growth by binding to DNA and RNA, preventing the synthesis of proteins necessary for cell division. The high chemical stability and low redox potential make 1-methylindole an excellent candidate for use as an anticancer agent. This drug has been shown to be effective in killing cancer cells in vitro, but more research needs to be done before it can be used in vivo.</p>

<p>5-Bromo-2-methoxypyridine is a synthetic organic chemical that is used in organic chemistry. It is a precursor to the HIV integrase inhibitor, PSC 833, and has been shown to be effective in treating idiopathic pulmonary fibrosis. 5-Bromo-2-methoxypyridine is synthesized by reacting phosphorus oxychloride with 2-bromomethoxybenzene. This reaction produces a mixture of products that are then separated using column chromatography. The desired product can be purified by recrystallization or distillation. 5-Bromo-2-methoxypyridine has three pairs of asymmetric carbon atoms and four different functional groups: halides, sulfur trifluoride, bromine, and methoxy groups.</p>

<p>3,6-Dichloropyrazine-2-carbonitrile is a synthetic nucleophilic compound that can be used to produce antiviral drugs. This chemical belongs to the class of chlorination compounds and reacts with nucleophiles in a nucleophilic substitution reaction. 3,6-Dichloropyrazine-2-carbonitrile has been optimized for synthesis by recrystallization and solvents. The reactants are heated and then mixed, where it undergoes an acid catalyzed hydrolysis followed by a dehydration reaction. 3,6-Dichloropyrazine-2-carbonitrile is synthesized by reacting a nitrile with phosgene to form the chloroformate ester which is reacted with ammonia or amines. The final product is purified using recrystallization or solvent extraction.</p>

<p>2-Chloro-3-pyridinecarboxyaldehyde is a synthetic molecule that contains two chlorines and three pyridines. It is a potential drug for the treatment of cancer or tuberculosis. The synthesis of this compound starts from 2,4-dichlorobenzaldehyde and 3-amino-5-(chloromethyl)pyridine. The reaction with acetic acid yields 2-chloro-3-pyridinecarboxyaldehyde. This product has been shown to inhibit cancer cells in vitro, but it does not have any effect on healthy cells. In addition, this product can be used as an anticancer agent against cervical cancer cells in vitro.</p>

<p>Isatin is a natural compound that can be found in the bark of the Cinchona tree. It has inhibitory properties against the enzyme polymerase chain reaction (PCR) and has been shown to have antimicrobial activity. Isatin also has an effect on 5-HT concentrations, which may be due to its ability to inhibit platelet aggregation and induce vasoconstriction. Isatin has been shown to have anticancer effects in vitro, and also inhibits cellular transformation by reducing DNA synthesis.</p>

<p>2,6-Dichloropyrimidine-4-carboxylic acid is a pyrimidine that can be used as a starting material for the synthesis of other compounds. It is an intermediate in the manufacture of anilines and pyrimidines. 2,6-Dichloropyrimidine-4-carboxylic acid is also used in the production of dyes and agrochemicals.</p>

<p>Please enquire for more information about 3-((4-Benzylpiperazinyl)carbonyl)pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Hydroxyoxindole (5HO) is a naturally occurring molecule that is found in oxindole and other indoles. It has been shown to have regulatory effects on inflammatory diseases, notably in the treatment of colitis. 5HO possesses significant cytotoxicity against carcinoma cells and also has radical scavenging activity. This compound can be synthesized using a solid-phase synthesis method. The presence of 5HO in skin cells has been correlated with the production of skin pigment called melanin. In addition, this molecule has been shown to bind to picolinic acid, which may contribute to its anti-inflammatory properties. 5HO is also present in neurologic disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.</p>

<p>8-HQ, liberated by enzymatic activity, is a strong metal chelator and forms insoluble, grey precipitates with several metal cations such as Fe3+</p>

<p>Please enquire for more information about 2-(Tributylstannyl)pyrimidin-5-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7H-imidazo[4,5-d]pyrimidine is a small molecule that exhibits receptor activity against toll-like receptors. It has been shown to inhibit the production of proinflammatory cytokines and chemokines in HL60 cells. 7H-imidazo[4,5-d]pyrimidine also inhibits the activities of enzymes involved in purine metabolism and cellular metabolic processes, as well as intracellular targets including protein kinases, phosphatases and transcription factors. 7H-imidazo[4,5-d]pyrimidine has been shown to be effective against solid tumours such as murine sarcoma virus and plant tumors. This drug also inhibits the enzymatic activity of p2y receptors that are involved in inflammation and platelet aggregation.</p>

<p>Indole-3-propionamide is a synthetic molecule that has been shown to have preventative effects against autoimmune diseases. It inhibits the production of IL-2, an important cytokine in the immune system, and also has an inhibitory effect on energy metabolism. Indole-3-propionamide has been shown to be neuroprotective in animal models and clinical studies have shown it to be safe for use in humans. Studies have also revealed its ability to bind to the IL2 receptor and inhibit cell proliferation.</p>

<p>Ethyl 4-butoxy-5-fluoro-2,6-dioxohexahydropyrimidine-5-carboxylate is a drug that has been used in clinical studies for the treatment of primary brain tumors. It has shown clinical response rates of up to 87%, with the most favourable response observed in patients with low tumor grade and well differentiated histology. The drug is administered orally and penetrates tissues, including the central nervous system. Ethyl 4-butoxy-5-fluoro-2,6-dioxohexahydropyrimidine-5 carboxylate has been found to be toxic to ameloblasts and cancer cells in vitro. Tumor regression was observed in animals treated with ethyl 4 butoxy 5 fluoro 2 6 dioxohexahydropyrimidine 5 carboxylate, which led to decreased symptoms such as weight loss and cachexia.</p>

<p>Intermediate in the synthesis of baricitinib</p>

<p>4,6-Dihydroxy-2-methylpyrimidine is a monomer that is used in the synthesis of polyurethanes. It is an intermediate in the reaction between hydrochloric acid and nitrous acid, which produces 4,6-dichloro-2-methylpyrimidine. The reaction mechanism involves transfer of a methyl group from an organic molecule to hydrochloric acid. This reaction can be carried out at either low or high pH values. The addition of magnesium salt increases the rate of the reaction by increasing the solubility of chloroformate in water. When ethyl esters are used as starting materials, a constant conversion rate can be obtained with a large excess of magnesium salt.</p>

<p>4-Amino-2-benzylamino-6-phenyl-1,3,5-triazine is a high quality chemical that can be used as a reagent in organic synthesis. This compound is also a useful intermediate and has been used as a building block in the preparation of various pharmaceuticals. 4-Amino-2-benzylamino-6-phenyl-1,3,5-triazine has CAS No. 693241-47-3 and is an important speciality chemical for research purposes. It is also versatile and can be used as a reaction component for the synthesis of other compounds.</p>

<p>4,6-Dichloropyrimidine is an intermediate in the production of malonic acid. It is also used as a process optimization agent in the synthesis of hydrochloric acid and water vapor. 4,6-Dichloropyrimidine reacts with hydrogen chloride to form a chlorinating agent that can be used for the chlorination of amines and alcohols. The reaction product is hydrochloric acid and dichloropyrimidine. This intermediate can also be used to synthesize amides through a Suzuki coupling reaction with hydroxyl groups, amines, and n-dimethyl formamide.</p>

<p>6-Chloro-3-aminopyridine-2-carboxamide is a small molecule that inhibits tumor growth in human prostate cancer cells. It binds to a pharmacophore, which is a three dimensional arrangement of atoms that is responsible for the biological activity of the drug. This compound has been shown to inhibit tumor cell proliferation and induce apoptosis. 6-Chloro-3-aminopyridine-2-carboxamide also inhibits the oncogenic signaling pathways, including the PI3K/Akt and MAPK pathways, leading to antiproliferative activity in cancer cell lines. 6-Chloro-3-aminopyridine-2-carboxamide also inhibits phosphorylation of Akt and Erk1/2, which are downstream targets of PI3K/Akt pathway activation. The compound was found to have no significant effects on noncancerous cells or normal prostate tissue.</p>

<p>4,5-Dichloro-3-hydroxypyridazine is an organic compound that is used as a precursor to other compounds. It has been shown to be genotoxic and mutagenic in a number of assays with mammalian cells. 4,5-Dichloro-3-hydroxypyridazine reacts with phenols in the presence of Friedel-Crafts catalysts to form pyridine derivatives. It has also been shown to regulate transcriptional activity by binding to the prostacyclin receptor and α2-adrenergic receptor. This compound has been studied for its potential diagnostic value in the diagnosis of triticum aestivum (wheat) sensitivity.</p>

<p>2-Methylthiopyrimidine-4,6-diamine is a potent inhibitor of the enzyme DNA polymerase. It has shown to be effective against hepg2 cells and other cancer cells. The compound binds covalently to the active site of the enzyme, where it stabilizes the transition state and deshields the electrostatic field around the nucleophilic nitrogen atom. This interaction leads to a decreased affinity for ATP, which is required for DNA synthesis. 2-Methylthiopyrimidine-4,6-diamine also has antimalarial activity and inhibits amide bond formation in hepg2 cells.</p>

<p>Piperacillin is a β-lactam antibiotic that inhibits the synthesis of bacterial cell walls by binding to penicillin-binding proteins. It is used for the treatment of serious infections caused by gram-negative organisms such as Aerogenes, Enterobacter, and Klebsiella. Piperacillin has a high MIC90 value against Staphylococcus and other gram-positive bacteria, but it is not active against β-lactamase producing strains of bacteria such as E. coli or Klebsiella pneumoniae. The MIC90 values are determined through an analytical method on different strains of bacteria and validated with a sample preparation before use in clinical trials.</p>

<p>Plant hormone; auxin; inducer of root development; used in plant rooting</p>

<p>2,4-Dimethyl-5-nitropyridine is a hydroxyurea analog that inhibits the synthesis of ribonucleotides by competitively binding to the enzyme ribonucleotide reductase. This inhibition leads to the accumulation of diphosphate and deoxyribonucleotides, which are necessary for DNA synthesis. 2,4-Dimethyl-5-nitropyridine was found to be more potent than hydroxyurea as an inhibitor of cellular growth in vitro and cancer cell lines in vivo. The potency of 2,4-dimethyl-5-nitropyridine can be attributed to its ability to bind very tightly with ribonucleotide reductase and form a stable complex.</p>