Glycoscience

<p>5-Thio-L-fucose is a sugar that is found in a variety of tissues and organs. It has been shown to inhibit the antibody-dependent cellular cytotoxicity (ADCC) by binding to the Fc portion of IgG antibodies, which are used to target and destroy cancer cells. 5-Thio-L-fucose has also been shown to modulate the effector functions of natural killer cells and enhance the glycan profile of dendritic cells. It may be useful as a supplement for patients undergoing chemotherapy or radiation therapy, where it may help inhibit the growth of tumor cells. 5-Thio-L-fucose inhibits ADCC activity by binding to IgG antibodies, preventing them from attaching to immune cells, which would otherwise act as effectors in destroying tumor cells. This inhibition can be reversed with a competitive inhibitor such as D-arabinose.</p>

<p>Irbesartan N-b-D-glucuronide is a complex carbohydrate that is a synthetic saccharide. It is an intermediate in the synthesis of irbesartan, which is an angiotensin II receptor antagonist. Irbesartan N-b-D-glucuronide has been shown to have antihypertensive properties, inhibiting the activity of the renin-angiotensin system and increasing blood flow to the kidneys. It also inhibits the growth of cancer cells. This compound can be custom synthesized for your specific needs and purities can be controlled to meet your specifications.</p>

<p>2-Acetamido-3,4,6-tri-O-acetyl-1-O-[(N-Cbz-aminoethoxy)ethoxy]-2-deoxy-b-D-galactopyranose is a custom synthesis of a complex carbohydrate. It is a polysaccharide that contains fluorine and has been modified with methylation, glycosylation, click modification, and polysaccharide modifications. 2-Acetamido-3,4,6-tri-O -acetyl -1 -O-[(N -Cbz -aminoethoxy)ethoxy] -2 deoxy b D galactopyranose is also known as CAS No. 1261568 35 7 and it's molecular weight is 546.81 g/mol.</p>

<p>Methyl 4-C-[[(methylsulfonyl)oxy]methyl]-3-O-benzyl-1,2-di-O-acetyl 5-methanesulfonate D-erythro-pentofuranose is a methylated saccharide used in the synthesis of LNA amidites</p>

<p>Safflor Yellow A is a natural drug that has been shown to have hypoglycemic effects. It is a potent inhibitor of glucose-6-phosphatase and glucose-6-phosphate dehydrogenase, which are enzymes involved in the conversion of glucose to glycogen. Safflor Yellow A also inhibits neuronal death, as it blocks the enzyme activities that lead to neuronal cell death. This drug has also shown antitumor activity, as it induces apoptosis in tumor cells. Safflor Yellow A also has antihyperlipidemic effects and can be used for the treatment of coronary heart disease. Low doses of this drug have been shown to reduce systolic pressure in rats and improve blood coagulation. The mechanism of action for this drug is not yet known but may involve toll-like receptor 4 signaling pathways or polymerase chain reaction (PCR).</p>

<p>2-Deoxy-D-glucono-1,5-lactone is a crystalline compound that is isolated from the hydrolysis of D-gluconic acid. This compound has been found to be a diastereoisomeric product with a lactone ring and an epimerization process. It can also be synthesized by reacting epichlorohydrin with potassium hydroxide in the presence of a hydroxy group. 2DG is an elimination product of 2-deoxyglucose and has been shown to have antihyperglycemic effects due to its ability to inhibit glucose synthesis in the liver and muscle cells. This compound also inhibits protein synthesis in bacteria, which may lead to cell death.</p>

<p>D-Glucose-6-phosphate barium salt is a custom synthesis that is prepared by modification of D-glucose with phosphoric acid, fluorination, methylation, and monosaccharide. This compound is a synthetic carbohydrate that belongs to the category of oligosaccharides and polysaccharides. It has a molecular weight of 583.12 g/mol and an empirical formula of C7H8O10P2Ba. The CAS number for this compound is 150400-00-3.</p>

<p>Please enquire for more information about 3'-methoxy apiin;Chrysoeiol-7-(2-O-apiosylglucoside) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Acetylmuramic acid 6-phosphate is a molecule that belongs to the class of compounds known as nucleotide phosphates. It is an intermediate in the biosynthesis of peptidoglycan, which is a major component of bacterial cell walls. N-Acetylmuramic acid 6-phosphate is synthesized from ATP and N-acetylmuramic acid by hydrolysis. The reaction mechanism for this transformation involves an imine intermediate, which can be formed through the action of two molecules of ATP and one molecule of N-acetylmuramic acid. This reaction is catalyzed by an enzyme called heterocyst. The enzyme kinetics for this transformation are influenced by many factors, including temperature, pH, and substrate concentration.</p>

<p>2,5-Anhydro-D-glucitol-1,6-diphosphate is a cell signaling molecule that is involved in the regulation of glycolysis and the phosphofructokinase enzyme. It binds to platelets and regulates platelet aggregation. This enzyme has been shown to be a potential drug target for cancer. Cancer cells have been found to contain higher concentrations of 2,5-Anhydro-D-glucitol-1,6-diphosphate than their normal counterparts. The increased concentration of this enzyme in cancer cells is due to an allosteric change in the enzyme’s activity. The increased activity leads to a more rapid metabolism of glucose, which provides energy for tumor growth and metastasis. This enzyme can be used as a marker for malignancy in human diseases such as breast cancer or prostate cancer.</p>

<p>In plants and algae, the two main galactolipids, monogalactosyldiacyglycerol (MGDG) and digalactosyldiacyglycerol (DGDG), are synthesized by galactosyltransferases in the plastid envelope. They have been linked to the anti-inflammatory and cancer benefits of a green leafy vegetable diet in humans due to their ability to regulate the levels of free radicals like nitric oxide (NO)</p>

<p>2,3,4,6-Tetra-O-acetyl-D-mannopyranose is a stereoselective technique used for the production of trisaccharides. It is also an acetylated form of D-mannopyranose that is obtained by acetylation of D-mannopyranose with acetic anhydride in the presence of hydrochloric acid or pyridine. The compound can be obtained as either levorotatory or dextrorotatory isomers depending on whether the hydroxyl group or carbonyl group are in the axial position. 2,3,4,6-Tetra-O-acetyl-D-mannopyranose can be used as a substrate for enzyme preparations to produce aminoglycoside antibiotics such as hygromycin A. Acetylation increases the solubility and stability of this drug and reduces its toxicity to humans</p>

<p>1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose is a carbohydrate that has been shown to bind to the lectin domain of the human insulin receptor. This binding is thought to modulate the activity of this protein. The carbohydrate has also been shown to inhibit the uptake of galactose by pancreatic beta cells in vitro. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose is postulated to have anti cancer properties and may be used as a blocker for tumor growth.</p>

<p>Lipid IVA is a tetra-acylated precursor molecule of lipid A which is a component of lipopolysaccharides (LPS) on the outer membrane of gram-negative bacteria. On the innate immune cells of hosts there are toll-like receptor 4 (TLR4) and MD-2 which recognize LPS. This recognition event ultimately leads to the activation of NFκB which in turn results in pro-inflammatory cytokine production. Studies have suggested lipid A in Escherichia coli to be an agonist for both mouse and human TLR4, while lipid IVA can induce species specific TLR4 responses. For example for horse and mouse TLR4 and MD-2, Lipid IVA is an agonist where as it is an antagonist for TLR4 and MD-2 in humans.</p>

<p>Please enquire for more information about Mono-(6-(diethylenetriamine)-6-deoxy)-β-Cyclodextrin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Acetyl-2,7-anhydro-a-neuraminic acid is a synthetic derivative of a naturally occurring sugar that is found in the human brain and other tissues. It has been proposed as a potential drug for the treatment of inflammatory bowel disease due to its ability to inhibit the growth of cells in the colon and prevent inflammation. N-Acetyl-2,7-anhydro-a-neuraminic acid has been shown to have antiinflammatory properties by inhibiting the synthesis of proinflammatory cytokines. This compound binds to an enzyme called galactosamine kinase, which is involved in making certain proteins that are necessary for inflammation. The chemical structure of N-Acetyl-2,7-anhydro-a-neuraminic acid was determined through structural analysis and carbon source titration calorimetry. Magnetic resonance spectroscopy showed that this compound reacts with water molecules and chemical ionization revealed that it</p>

<p>Dipyridamole di-O-b-D-glucuronide is a fluorinated oligosaccharide that has been synthesized using the click chemistry reaction. It is a monosaccharide that has been glycosylated and modified with methyl groups to produce a high purity product. The carbohydrate consists of one or more sugar units linked by glycosidic bonds. Carbohydrates are classified by their number of sugar units and by the presence of other chemical groups such as phosphate, sulfate, or hydroxyl. This product is also used in the synthesis of complex carbohydrates and polysaccharides.</p>

<p>Lactose-PAA-biotin is a biotin linked to lactose by a polyacrylamide linker</p>

<p>2-AB labeled core pentasaccharide found in most N-linked oligosaccharides.  Purified from the oligosaccharide pool released from bovine serum by hydrazinolysis using a combination of HPLC and glycosidase digestion.</p>

<p>Heparin derived disaccharide sodium salt is a salt form of heparin. It is a heterogenous mixture of low molecular weight compounds that are composed of sugar residues and sulfation. Heparin derived disaccharide sodium salt has been used for the treatment of thrombocytopenic purpura, thrombotic thrombocytopenic purpura, and other bleeding disorders. This drug also has been used to prevent blood coagulation in patients undergoing surgery.</p>

<p>3-Acetamido-3,6-dideoxy-D-galactose is a monosaccharide with two functional groups. It has been shown to be bifunctional and can act as a glycosyl donor or acceptor. 3-Acetamido-3,6-dideoxy-D-galactose was isolated from the type strain of Streptomyces venezuelae. It is also found in fatty acids and some strains of bacteria, such as Bacillus megaterium. The biological properties of 3-acetamido--3,6-dideoxy--D--galactose have been studied using monoclonal antibodies, magnetic resonance spectroscopy (MRS), and 13C nuclear magnetic resonance spectroscopy (NMR).</p>

<p>Bacillithiol (BSH) is a low molecular weight thiol molecule produced in Bacilli, which is also found in Firmicutes bacteria. It plays an important role in maintaining the balance of reactive oxygen species within cells and detoxifying certain harmful compounds. It is the α-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid and it seems to have antioxidant properties. Bacillithiol plays an important role in bacterial redox homeostasis and plays an important role in the detoxification of electrophiles as it is a cofactor for FosB (thiol transferase). <br>This is the salt form (trifluoroacetic acid salt, TFA) of Bacillithiol.</p>

<p>Quaternization of the primary amine in N-Trimethylchitosan increases the water solubility of chitosan and keeps chitosan soluble over a wide pH range. N-Trimethylchitosan is soluble in water and ethanol, making it ideal for use in biotechnology applications.The degree of quaternization is 30-70%</p>

1,6-Di-O-galloyl-β-D-glucopyranose is a plant active compound that has been shown to have insecticidal and antifungal properties. It is also an inhibitor of serine proteases. 1,6-Di-O-galloyl-β-D-glucopyranose may be used to control the spread of human immunodeficiency virus (HIV) in humans. In an in vitro study, 1,6-di galloyl β-D glucopyranose was found to inhibit HIV by binding to the viral envelope gp120 protein and preventing it from attaching to CD4 receptor sites on T cells. This inhibition prevents the virus from entering the cell and infecting it. 1,6 - di - O - galloyl - β - D - glucopyranose also inhibits HIV by blocking its entry into the host cell through interaction with gp41 protein on the

<p>β-1,3-Glucan is a bioactive polysaccharide, which is located predominantly in the cell walls of yeast, fungi, and certain cereals. This compound is characterized by its unique branched structure, which is crucial for its biological function. The mode of action of β-1,3-Glucan involves the binding to specific receptors on immune cells, such as dectin-1, which triggers a cascade of immune responses. This interaction enhances the activity of macrophages, neutrophils, and natural killer cells, thus bolstering the body's innate immune defenses.The uses and applications of β-1,3-Glucan are broad, primarily focused on immunological research and potential therapeutic strategies. It is extensively utilized in studies examining its effects as an immunomodulator, leveraging its ability to potentiate immune system function and examining its role in adjunctive cancer therapies, where it may enhance the efficacy of certain treatments. Additionally, β-1,3-Glucan is investigated for its potential benefits in reducing infection rates and improving recovery times in clinical settings. Moreover, its applications in dietary supplements and functional foods continue to be a subject of scientific inquiry, aiming to harness its health-promoting properties within nutrition science.</p>

<p>Inhibitor of alpha-glucosidase</p>

<p>Intermediate in the synthesis of empagliflozin</p>

<p>1,2,3-Tri-O-methyl-D-glucopyranoside is a custom synthesis and modification of the natural product 1,2,3-tri-O-methyl-D-mannopyranoside. The compound was synthesized by fluorination of the 3' hydroxyl group followed by methylation of the 2', 3' hydroxyl groups to form a triol. This sugar was then glycosylated with D-glucose to produce an oligosaccharide. 1,2,3 - Tri -O - methyl - D - glucopyranoside is a natural product that can be found in plants such as barley and wheat. It has been shown to have antiinflammatory properties.</p>

<p>Gycosaminoglycan in many organs; joint lubricant and shock absorber.  Made by a bacterial, Streptococcus fermentation.</p>

<p>2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl chloride is a carbohydrate that has been modified by fluorination. It is used as an ingredient in the synthesis of saccharides and oligosaccharides. This product is synthesized by the reaction of 2,3,4,6-tetra-O-acetylmannose with chlorodifluoromethane in the presence of a base.</p>

<p>Tetradecyl b-D-maltopyranoside is a crystalline polymer of high molecular weight that is made up of repeating units of tetradecyl b-D-maltose. It has a lamellar morphology and can be sectioned with techniques such as electron microscopy, X-ray diffraction, and differential scanning calorimetry. Tetradecyl b-D-maltopyranoside is a metastable form of the compound. It has been found in nature in the form of the monomer unit, tetradecyl maltosyl (tetramethyleneglycol) b-d-maltoside. In order to produce this compound as a polymer, it must first be heated to about 160°C for several hours, which causes the monomers to assemble into chains of tetrahedrons. The properties of tetradecyl b-D-maltopyranoside depend on its environment</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Please enquire for more information about D-Mannose tablets including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonate is a synthetic oligosaccharide that is used in the synthesis of glycosides. The carbohydrate has been modified to include fluorination and glycosylation. This product can be custom synthesized to meet your specifications.</p>

<p>2-Benzamido-2-deoxy-D-glucopyranose is a synthetic, inexpensive, and non-toxic compound that has antibiotic properties. It is used as a reagent for the sulfonylating of aromatic rings and as an intermediate in the synthesis of other compounds. 2-Benzamido-2-deoxy-D-glucopyranose can be radiolabeled with carbon or fluorine atoms to form a resonance labeled probe that can be used in magnetic resonance spectroscopy.</p>

<p>Please enquire for more information about D-Maltose monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benzyl 2-acetamido-2-deoxy-α-D-glucopyranoside is a synthetic compound with a molecular weight of 342.45 g/mol. It is a white to pale yellow crystalline solid that is soluble in water and methanol. The chemical formula for this compound is C12H14N2O6 and its structural formula is represented as CH2(COOCH3)COOC8H11O6. The CAS number for this compound is 13343-62-9, and the IUPAC name for it is benzyl 2-(2-acetamido)-2,3,4,5,6-pentaacetoxy αDglucopyranoside. This compound has been used in methylation reactions and click chemistry applications due to its ability to form stable carbonyl bonds with other molecules. Benzyl 2-(2-acetamido)-2,3,4,5,6</p>

<p>D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-Gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance</p>

<p>Please enquire for more information about Glucosamine L-5-methyltetrahydrofolate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Globotriaosylsphingosine is dramatically increased in plasma of classically affected male Fabry patients and plasma and tissues of Fabry mice. Globotriaosylsphingosine was shown to be an inhibitor of α-galactosidase A activity. Furthermore, exposure of smooth muscle cells, but not fibroblasts, to globotriaosylsphingosine at concentrations observed in plasma of patients promotes proliferation. It was suggested that measurement of circulating globotriaosylsphingosine would be useful to monitor Fabry disease and may contribute to a better understanding of the disorder.</p>

<p>4-Nitrobenzyl b-D-thiogalactopyranoside is a synthetic glycosylation agent that can be used for the modification of saccharides and oligosaccharides. The product is available in different purity grades, custom synthesis, and custom modifications.</p>

<p>GT3 oligosaccharide (free acid) is a disaccharide (Galβ1,4Glc) with three sialic acid residues (NeuAc) linked α2,8/α2,8/α2,3 to the galactose residue (Ledeen, 2009). The GT3 ganglioside is the carbohydrate moiety in the GT3 ganglioside, which is implicated in type 1 diabetes. GT3 ganglioside is expressed on pancreatic cells and is the target antigen of anti-GM3-antibodies, which contribute to the autoimmune destruction of pancreatic beta cells (Misasi, 1997). GT3 ganglioside is also abundant in lung tissues and the nervous system.</p>

<p>Cellulose acetate fiber is one of the earliest synthetic fibers and is based on cotton or tree pulp cellulose. Cellulose acetate is used as a film base in photography, as a component in some coatings, and as a frame material for eyeglasses.  It is also used as a synthetic fiber in the manufacture of cigarette filters and playing cards. In photographic film, cellulose acetate replaced nitrate film in the 1950s, being far less flammable and cheaper to produce but in recent years has been rendered obsolete by the advent of digital cameras.</p>

<p>Methyl b-D-fructofuranoside is a chemical compound that is used in the production of esters and fatty acids. Methyl b-D-fructofuranoside is produced by a dehydration reaction between two molecules of acetone. The product of this reaction, methyl b-D-fructopyranoside, can be broken down into two molecules of acetone and one molecule each of methyl alcohol and carbon dioxide. This process is called alkylation. Furanocoumarin derivatives are often found in plants such as asperulosidic acid and quinquefasciatus. These compounds are found in many species of plant, but they are most concentrated in the roots of these plants because they are more metabolically active there than other parts of the plant. Environmental pollution can lead to high concentrations of furanocoumarins in plants, which can have toxic effects on organisms that come into contact with them.</p>

<p>N-Oleoyl-N-Methyltaurine sodium salt is a glycol ether that has been shown to be an effective transport inhibitor for fatty acids. It inhibits the growth of bacteria and fungi by interfering with the cell membrane lipid synthesis. N-Oleoyl-N-Methyltaurine sodium salt also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Sodium alginate is the sodium salt of a polysaccharide obtained from brown seaweeds. The main use for alginate is in textile printing as a thickener in the printing of cottons with reactive dyes. In the food industry it is used as a thickener and gelling agent. The chemical structure consists of blocks of (1,4) linked-β-D-polymannuronic acid (poly M), (1,4) linked-α-L-polyguluronic acid (poly G) and alternating blocks of the two uronic acids (poly MG).</p>

<p>D-Glucosamine-3,4,6-tri-O-sulphate trisodium salt is a high purity and custom synthesis of D-glucosamine. It is a sugar with click modification and fluorination. It has CAS No. 157297-03-5 and it is synthesized from glycosylation, methylation, and modification. It has a molecular weight of 517.85 g/mol and the chemical formula C9H14N2O12S3NaO6. Glucosamine is an oligosaccharide that can be found in many complex carbohydrates such as chitin or cellulose.</p>

<p>3'-b-Sialyl-N-acetyllactosamine is an oligosaccharide that is synthesized from L-arabinose and 3'-phosphoadenosine 5'-phosphosulfate. It has a high degree of purity and is custom synthesized to order. The CAS number for this product is 210418-18-1.</p>

6-Deoxy-6-iodo-D-glucose is a glucose analog that can be used as a bypassed substrate for the study of d-glucose metabolism in diabetic patients. 6-Deoxy-6-iodo-D-glucose has been shown to be an acceptable substrate for animal cells and can be used for the study of glucose uptake in the pancreas. This analog does not require insulin for uptake, which may help to elucidate the role of insulin resistance in diabetes. The use of 6-deoxy-6-[18F]fluoroethyl D-[1,2]-glucose ([18F]FDG) as an optical imaging agent has also been studied.

<p>6-Deoxy-6-mercapto-gamma-cyclodextrin, octakis (Methyl 6DG) is a novel and unique sugar with two methyl groups on the C6 hydroxyl position. It has been synthesized from glucose by a click modification reaction and can be used as an alternative to 6DG for the production of oligosaccharides and polysaccharides. The high purity of Methyl 6DG makes it suitable for use in analytical research, such as fluorescence resonance energy transfer measurements.</p>

<p>1,2,3,4-Tetra-O-acetyl-D-glucuronide methyl ester is a lactone that can be used as a precursor for the synthesis of various types of compounds. The chemical structure was determined by high-resolution x-ray diffraction to be a planar molecule with two conformations: one where the four acetyl groups are on different sides and another where they are all on the same side. The latter conformation is more stable due to the dihedral angle between the hydroxyl group and carbonyl group. This compound is an intermediate in synthesizing 2-(4'-hydroxybenzoyl)-1,2,3,4-tetra-O-acetyl-.alpha.-D-.beta.-D glucopyranoside methyl ester by reacting with 3-(3'-azido)benzaldehyde. The single crystal x-ray diffraction study revealed that this compound has a conformation</p>

<p>6-Phosphogluconic acid trisodium is a synthetic, non-natural glycosylation product that is used as a building block in the synthesis of complex carbohydrates. It can be fluorinated or methylated, and modified with a click reaction to produce various derivatives. The compound has been shown to have high purity and is readily available from commercial suppliers.</p>

<p>Cornuside is a natural compound that is found in the fruits of Cornus. It is a dihydrochalcone, which has been shown to have hypoglycemic effects and inhibit the activity of 5-hmf. Cornuside also inhibits the enzyme activities involved in energy metabolism, such as glucose-6-phosphate dehydrogenase and hexokinase. It has also been shown to have genotoxic properties and induce DNA damage. Cornuside may be useful for treating diabetes or cancer, but further research needs to be done before this can be confirmed.</p>

Onitin 2'-O-glucoside is a sugar that is custom synthesized and purified. It is a modification of oligosaccharides, complex carbohydrates, and polysaccharides. Onitin 2'-O-glucoside is an Oligosaccharide Carbohydrate which can be used in the synthesis of high purity monosaccharides and methylations. It also has the ability to form glycosylation with saccharides, such as glucose or fructose. This product can also be fluorinated to produce saccharides that are water soluble.

<p>N-Acetyl-D-glucosamine-3-6-di-O-sulfate sodium salt is a synthetic oligosaccharide. It is a fluorinated glycosylic acid glycosidase, an enzyme that catalyzes the hydrolysis of beta-(1,2)-glycosidic linkages in polysaccharides. This product can be custom synthesized to meet your specifications and can be modified with methylation or click modification for your specific needs.</p>

<p>Please enquire for more information about L-Heptaguluronic acid heptasodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>D-Fructose-1,6-diphosphate dibarium salt is a synthetic sugar that is used in the synthesis of oligosaccharides and polysaccharides. This compound can be custom synthesized to meet your specifications. D-Fructose-1,6-diphosphate dibarium salt has been shown to be soluble in water, ethanol, acetone, and chloroform. D-Fructose-1,6-diphosphate dibarium salt is a fluorinated carbohydrate with a purity of 99%. It can be modified with methylation or click modification for further applications.</p>

<p>2-Acetamido-1,3,6-tri-O-acetyl-2,4-dideoxy-4-fluoro-D-glucopyranose is a high purity synthetic glycosylate with a custom synthesis. It is an oligosaccharide that has been modified for fluorination and methylation. This product is used as an intermediate in the production of complex carbohydrates.</p>

<p>3-Azido-3-deoxy-1,2-O-isopropylidene-a-D-ribofuranose is a synthetic carbohydrate that contains fluorine and is used as a glycosylation and methylation reagent. It has been shown to react with various saccharides, including glucose, maltose, lactose, sucrose, and cellobiose. In addition to its use in glycosylation reactions, 3-azido-3-deoxy-1,2-O-isopropylidene -a D ribofuranose can be used for click chemistry. This reagent is available in high purity and is synthesized from the natural sugar ribofuranose.</p>

L-Lyxosamine HCl is a synthetic monosaccharide that has been modified to contain a fluorine atom. L-Lyxosamine HCl is a methyl donor in the Methylation reaction and can be used as an intermediate for the synthesis of oligosaccharides and polysaccharides. This product is available in high purity, with an average yield of 97%. The CAS No. for this product is 590-81-6.

<p>Phenyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranoside is a fluorinated synthetic monosaccharide that has been synthesized to serve as a glycosylation and polysaccharide modification agent. Phenyl 3,4,6-tri-O-acetyl-2-deoxy-2--phthalimido--b--D--glucopyranoside is an effective methylation agent for the synthesis of complex carbohydrates. It can be used for click modifications on the sugar moiety of oligosaccharides and polysaccharides. Phenyl 3,4,6 -tri -O -acetyl -2 -deoxy -2 -phthalimido -b -D--glucopyranoside is soluble in water as well as many organic solvents. The CAS No. 120498 97 7 is assigned to</p>

<p>Globotriose-sp-biotin is a custom synthesis that contains a fluorinated, methylated, and modified monosaccharide. It is a synthetic oligosaccharide with glycosylation at the reducing end. Globotriose-sp-biotin can be used in the modification of polysaccharides and complex carbohydrates to improve their bioactivity. This product has a CAS number of 127798-73-5 and is listed as an Oligosaccharide under Glycosylations in the Carbohydrate section.</p>

N-Propionyl-D-glucosamine is a sugar used in the synthesis of peptidoglycan, a structural component of bacterial cell walls. N-Propionyl-D-glucosamine is synthesized from formaldehyde and propionic acid. It is used as an antibiotic to treat bacterial infections caused by Gram-positive bacteria such as streptococci and staphylococci. N-Propionyl-D-glucosamine has also been shown to have anti-fungal properties against Candida albicans and Saccharomyces cerevisiae. The biosynthesis of this compound takes place through phosphorylation of the amide group on the sugar residue, which is catalyzed by a number of enzymes including phosphotransacetylase, acetate kinase, and phosphoenolpyruvate synthase. This process requires ATP, phosphate ions, ammonium ion, and water molecules.

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>N-Acetylneuraminic acid hexamer disodium salt is a custom synthesis of a fluorinated, methylated and acetylated N-acetylneuraminic acid. This molecule is an oligosaccharide with three sugar rings. It has been modified by click chemistry and glycosylation to create a complex carbohydrate. The CAS number for this compound is 156587-48-2.</p>

Tween 65 is a polyoxyethylene sorbitan monooleate (polysorbate) surfactant that is used as a film-forming polymer and dispersing agent in solid preparations. Tween 65 has been shown to inhibit the proliferation of prostate cancer cells, which may be due to its ability to bind to anti-prostate specific antigen (anti-pcsk9) antibody causing the antibody to aggregate and form a particle. This process inhibits the interaction between the antibody and its target, preventing it from binding with PCSK9 protein. The addition of propranolol hydrochloride has been shown to increase the effectiveness of Tween 65.

<p>3,4,6-Tri-O-acetyl-1,2-O-ethoxyethylidene-b-D-mannopyranose is a synthetic monosaccharide that is used as a substrate for the production of various oligosaccharides and polysaccharides. This substance can be fluorinated to produce 3,4,6-tri-O-(3′,5′ -difluoro) acetyl-1,2:5′,6′ -di(O—ethoxyethylidene)-b-D mannopyranose. It has been shown that methylation of the C1 position in this compound results in a variety of different compounds with different properties. In addition to its use as a substrate in organic synthesis, 3,4,6 triacetyl 1,2:5', 6'-di(O—ethoxyethylidene)-b D mannopyranose is also</p>

<p>Kappa-Carrageenan is a gelling sulphated galactan extracted from red seaweed (typically Mastocarpus stellata and Chondrus crispus). The structure of all carrageenans consists of a strictly alternating masked repeating unit of 1,3-linked α-D-galactose and 1,4-linked β-D-galactose. The α-linked galactose occurs as α-3-6-anhydro unit and the β-linked sugar occurs as the 4-sulphate.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Glyco-diosgenin is an amphipathic molecule that has been found to stabilize proteins. It has the potential to be developed as a drug target for stabilizing proteins in cells. Glyco-diosgenin was synthesized by chemical modification of diosgenin, which is a steroidal saponin found in plants. The chemical modification that occurred at the 3-hydroxyl position of glyco-diosgenin produced a more effective molecule due to increased solubility and decreased toxicity. The protein stabilization properties of glyco-diosgenin have been shown by cryo-electron microscopy on plant cells, titration calorimetry, and functional studies on various proteins.</p>

<p>a-D-Glucoheptonic acid calcium salt hydrate is a modification of a glycosylation reaction that is typically used in the synthesis of oligosaccharides. The modification is called Click chemistry, and it occurs through a copper-catalyzed reaction between an azide and an alkyne. This type of modification can be used to produce complex carbohydrates by linking together different monosaccharides or polysaccharides. It is also used for the production of high-purity monosaccharides and polysaccharides with custom syntheses. The methylation, glycosylation, fluorination, and saccharide modifications are all variations on this process.</p>

<p>Benzyl 2,3-O-isopropylidene-a-D-mannofuranoside is a fluorinated monosaccharide that is synthesized using glycosylation and polysaccharide modification. This product has a CAS number of 20689-03-6 and can be used for complex carbohydrate synthesis. It has been shown to have high purity.</p>

<p>b-D-Glucopyranosyl nitromethane is a precursor for the synthesis of glyco-peptides</p>

<p>D-Fructose 1-phosphate barium salt trihydrate is a custom synthesis, high purity sugar. It has been modified with fluorination, glycosylation, and methylation. D-Fructose 1-phosphate barium salt trihydrate is made from the modification of various sugars such as oligosaccharides and monosaccharides to form complex carbohydrates. It can be used for Click modification or in the synthesis of glycoconjugates. D-Fructose 1-phosphate barium salt trihydrate is also known as saccharide.</p>

<p>2,5-Anhydro-1,3-O-isopropylidene-6-O-trityl-D-glucitol is a complex carbohydrate that is synthesized by the modification of glucose. This product has been modified with methylation and glycosylation.<br>2,5-Anhydro-1,3-O-isopropylidene-6-O-trityl--D--glucitol is a white powder that is soluble in water and ethanol. <br>It can be used for fluoroquinolone resistance studies, which are important for developing new antibiotics to combat bacterial infections.</p>

<p>Mefenamic acid-acyl-b-D-glucuronide is a synthetic drug that binds to albumin and human serum albumin. It has been shown to irreversibly inhibit human UDP-glucuronosyltransferase, an enzyme in the human liver that catalyzes the addition of glucuronic acid to drugs and other xenobiotics. Mefenamic acid-acyl-b-D-glucuronide has also been shown to inhibit the activity of a wide range of enzymes in humans, including isoenzyme UGT1A6, which is found in the liver and kidney. This drug has been studied as a potential treatment for pain and inflammation in humans.</p>

<p>Beta-rutinose is a potent kinase inhibitor that has shown anti-tumor activity in Chinese hamster ovary (CHO) cells. It inhibits the activity of cyclin-dependent kinases, which are essential for cell division and proliferation. Beta-rutinose has been shown to induce apoptosis in human cancer cells, making it a promising candidate for anticancer therapy. This compound is an analog of rutin, a flavonoid found in many plants, and has been shown to have potent anticancer effects in vitro and in vivo. Beta-rutinose inhibits the growth of cancer cells by blocking the activity of specific kinases involved in tumor progression, making it an attractive target for developing new cancer therapies. Additionally, this compound has been found to be effective at reducing protein levels associated with cancer cell growth and proliferation.</p>

<p>Phenethyl glucosinolate potassium salt is a compound found in plants belonging to the Brassicaceae family. It has been shown to be highly toxic to larvae of the cabbage butterfly and other insects that feed on brassica plants. Phenethyl glucosinolate potassium salt has been shown to inhibit the development of these insects, probably by inhibiting protein synthesis in the insect's gut. The major sulfur-containing compound in this product is gluconasturtiin, which has been shown to inhibit growth of pekinensis at high temperatures. This compound also inhibits radiation-induced DNA damage and does not show significant effects on nonsignificant organisms such as yeast and mold.</p>

<p>Chondroitin sulphate is an inhibitor that has been extensively studied in human and animal models. This active agent has been shown to have a protein inhibitory effect on epithelial cells, as well as an inhibitory effect on cell growth in Chinese medicine and Chinese medicinal plants. Chondroitin sulphate has been found to exhibit inhibitory activity against endothelial cells, which may be due to its ability to inhibit the nuclear translocation of NF-κB. This compound can be detected by liquid chromatography and has been shown to have a significant inhibitory effect on the proliferation of HepG2 cells. Overall, chondroitin sulphate shows great potential for use in healthcare products aimed at regulating cell growth and inflammation.</p>

<p>Inducer of cytochine and chemochine production in blood cells</p>

<p>β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a synthetic, nonsteroidal estrogen with a high affinity for the human estrogen receptor. It is used in the treatment of various types of breast cancer and as hormone replacement therapy. β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium is a part of the drug class selective estrogen receptor modulators (SERMs). The compound has been shown to have antiestrogenic activity through its ability to compete with estradiol for binding to the estrogen receptor. This compound also has some antiandrogenic effects and can inhibit sex hormone binding globulin (SHBG), leading to increased levels of free testosterone in blood plasma.</p>

<p>Blend of sucrose esters with fatty acid esters from coconut oil used in Cosmetic industry applications.</p>

<p>4-Methoxyphenyl 3-O-allyl-b-D-galactopyranoside is an antigen that is found on the surface of chronic lymphocytic leukemia cells. It is a highly reactive antibody that has been shown to be able to induce monoclonal antibody production in animals and humans. The antigen was first discovered in tissues from patients with chronic lymphocytic leukemia, but it has also been identified in tissues from other animals, including rabbits, rats, guinea pigs, and mice. 4MP3AG binds to the CD20 surface antigen on B cells. This binding leads to a conformational change in the antigen and exposes a new epitope on the molecule for binding by antibodies. The resulting antibodies are then used as diagnostic tools for chronic lymphocytic leukemia.</p>

<p>A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus vesiculotus, Ascophyllum nodosum, Alaria and Lessonia nigrescens (illustrated) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta.<br>The fucose content is approx. 26.2% and it also contains galactose (approx. 13.0%), uronic acid (approx. 13.0%) and sulfate (approx. 29.1%).<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>D-Arabinose-5-phosphate is an intermediate in the pentose phosphate pathway. It is synthesized from D-xylulose-5-phosphate by xylitol dehydrogenase. D-Arabinose-5-phosphate inhibits the enzyme xylitol dehydrogenase, which converts xylulose to d-xylulose, and thus prevents the formation of 5-hydroxyisoxazole phosphate, a precursor to the synthesis of NADPH. In this way, it blocks the synthesis of NADPH, which is essential for aerobic metabolism. This inhibition leads to a decrease in ATP production and consequently cell death.</p>

<p>Forodesine is a purine nucleoside that inhibits the nucleoside phosphorylase enzyme and prevents the synthesis of purines. It has minimal toxicity and is effective against intracellular targets such as mitochondria, which are important for apoptosis induction. Forodesine also inhibits the mcl-1 protein, which is an inhibitor of t-cell lymphomas. This drug has been shown to be effective in animal models of human lymphoma and leukemia.</p>

<p>11a-Hydroxy progesterone b-D-glucuronide is a fluorinated steroid that is synthesized with high purity. It has been modified with methylation and glycosylation. 11a-Hydroxy progesterone b-D-glucuronide is a complex carbohydrate, which consists of saccharides in the form of oligosaccharides. The sugar in 11a-hydroxy progesterone b-D-glucuronide is a monosaccharide, which can be modified with fluorination or click chemistry to create a new compound. This product has CAS No. 77710-64-6 and can be custom synthesized to meet your specifications.</p>

<p>Methyl 2-deoxy-5-O-toluoyl-L-ribofuranoside is a high purity, custom synthesis, methylated, Glycosylation and Oligosaccharide. It has CAS No. 676598-19-9 and is Glycosylated and Methylated. This complex carbohydrate is a synthetic, monosaccharide or saccharide that can be modified with fluorination, Click modification or glycosylation.</p>

<p>2,3,4,6-Tetra-O-benzyl-5-thio-D-glucono-1,5-lactone is a complex carbohydrate that can be modified with methylation and glycosylation. It is a saccharide that can be modified by fluorination and click modification. This compound is synthesized by the polymerization of allose in the presence of an enzyme to produce 2,3,4,6-tetra-O-(benzyloxymethyl)-5-thio--D--glucono--1,5--lactone.</p>

<p>2,3-O-Isopropylidene-L-glyceraldehyde (2,3-OIPA) is a synthetic compound that was developed as an alternative to paraformaldehyde for the synthesis of enantiopure compounds. It has been used in metathesis reactions and catalysed the conversion of β-unsaturated ketones to enantiopure products. 2,3-OIPA also has significant cytotoxic activity against a range of human cancer cell lines. This compound can be used in asymmetric syntheses to produce chiral molecules with a high degree of optical purity.</p>