Glycoscience

A linear β-(1,4)-galactan from potato tubers. Other linear β-(1,4)-galactans have been isolated from lemon peel, potato tubers and Norwegian acacia gum.

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Xanthan gum is a polysaccharide produced by the Gram negative bacteria Xanthomonas campestris. It has unique rheological and gel forming properties and finds many applications particularly in the food and oil industries. Recently, it has been shown that ternary mixtures of konjac glucomannan, xanthan gum and sodium alginate can form a non-covalently linked complex which exhibits enhanced rheological properties of value in, for example, functional foods. The structure of xanthan is based on a cellulosic backbone of β-(1,4)-linked glucose units which have a trisaccharide side chain of mannose-glucuronic acid-mannose linked to every second glucose unit in the main chain. Some terminal mannose units are pyruvylated and some of the inner mannose units are acetylated.

Propranolol D-glucuronide D6 is a synthetic, fluorinated, saccharide that is a modification of propranolol. It has high purity and can be custom synthesized to meet specific requirements. Propranolol D-glucuronide D6 has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. It is used in veterinary medicine to treat respiratory infections caused by Clostridium perfringens and other bacteria. The drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.

D-Galactose is a monosaccharide that is found in the cells of plants and animals. It can be synthesized from D-glucose by adding a D-galactose molecule to the alpha carbon of an existing glucose molecule. The resulting bond is called a glycosidic linkage. This process is called glycosylation. Glycosylation occurs when a sugar molecule reacts with another molecule, such as an amino acid, lipid, or nucleotide, to form what is known as a glycoside linkage. In this case, the sugar is D-galactose and the other molecules are either amino acids or lipids. The reaction between D-galactose and other molecules often results in polysaccharides and complex carbohydrates such as cellulose, chitin, and glycogen.
Methylation of D-galactose can produce methyl galactoside (CAS No. 1881-42-7), which

Glycolytic inhibitor; pro-apoptotic; anti-cancer agent

4-Deoxy-4-fluoro-D-glucopyranose is a fluorinated sugar that is found in the roots of Glycyrrhiza uralensis. It can inhibit glycosylation by blocking the stepwise addition of glucose to the growing oligosaccharide chain. 4-Deoxy-4-fluoro-D-glucopyranose also has biological activities, such as antiinflammatory and antitumor properties. This compound is an analog of D-arabinose and D-xylulose, which are found in many plants. 4DFG can be used to synthesize glycosides with various substituents on the hydroxyl group.

Glycosylation of azetidinol is a chemical reaction in which a glycosylate group is transferred from an activated sugar to the nitrogen atom of an azetidinone. It can be used for the synthesis of oligosaccharides and polysaccharides by transferring the glycosyl group to their nitrogen atoms. Click modification refers to a type of chemical reaction that was developed by K. Barry Sharpless in 1996, which uses copper-catalyzed azide-alkyne cycloaddition. This type of reaction has been used for the synthesis of complex carbohydrates with high purity and low cost, as well as for modifying sugars with methyl groups or fluorine atoms.

N-Acetyl-D-galactosamine-6-O-sulphate sodium is a carbohydrate that is used in the synthesis of oligosaccharides. The saccharide is fluorinated, methylated, and glycosylated. It also has a click modification at the reducing end. N-Acetyl-D-galactosamine-6-O-sulphate sodium is synthesized by custom synthesis and has high purity.

D-Gluconate 6-phosphate trisodium salt dihydrate is an oxidoreductase enzyme that catalyzes the conversion of D-gluconate 6-phosphate to D-glucono-6,1'-lactone. It is found in animals, where it is located in the cytoplasm and mitochondria. D-Gluconate 6-phosphate trisodium salt dihydrate has been shown to have a high kinetic activity in homogenates of rat liver and kidney, as well as in microsomes from rat liver. The enzyme also has a high affinity for phosphatidylethanolamine and low affinity for other lipids. This enzyme is inhibited by tetrazolium chloride and fatty acids.

Sialyllacto-N-fucopentaose V is a complex carbohydrate with the CAS No. 89458-13-9. The molecular weight of this compound is 597.07 g/mol, and it has the following chemical structure:

1-Chloro-1-deoxyribitol is a methylating agent that can be used for the synthesis of complex carbohydrates, such as oligosaccharides and polysaccharides. It is also used in click chemistry to modify saccharides with fluoride or other reagents. 1-Chloro-1-deoxyribitol is highly pure and stable, and is available in monosaccharide form. This compound is a synthetic sugar that has been modified to contain chlorine atoms at both the hydroxyl groups.

The Lewis A glycan is a complex carbohydrate that consists of a sulfated disaccharide and an oligosaccharide. The Lewis A glycan is a modification of the Lewis B glycan, which lacks the sulfate group. The saccharide component is a monosaccharide, and can be synthesized using custom synthesis or purchased from CAS No.

Methyl 2,3,4-tri-O-acetyl-6-O-triisopropylsilyl-a-D-mannopyranoside is a custom synthesis of a monosaccharide with a fluorinated methyl group. The compound has been synthesized by the Click modification of an oligosaccharide and polysaccharide. This product is available in high purity, and can be modified to suit your needs. For more information, please contact us today!

Estriol 3-O-b-D-glucuronide sodium salt is an estrogenic compound that is metabolized to 17β-estradiol, the most potent endogenous estrogen. Estriol 3-O-b-D-glucuronide sodium salt is found in wastewater and has been detected in effluent from various sources. The presence of estriol 3-O-b-D glucuronide sodium salt in wastewater indicates that it may be discharged from pharmaceutical manufacturing plants. It has been shown to be present at high concentrations in the effluent of a pharmaceutical plant that manufactures estrogens, which may have resulted from incomplete recovery during production. Estriol 3-O-b glucuronide sodium salt can be readily recovered by liquid chromatography with a reversed phase column and eluted with acetonitrile containing 0.1% trifluoroacetic acid (TFA). Recoveries are typically greater than 90%. Estrogen conjugates such

Chitosan is the deacetylated form of chitin.  The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid).  This then allows the material to be used in a number of industrial applications as a binder and film former.

Isoprimeverose is a covalently linked polysaccharide with a molecular weight of about 5,000. It has been shown to have an optimum pH at around 7.5 and is soluble in water. Isoprimeverose was found to be highly immunogenic in rats and mice, producing high levels of polyclonal antibodies against the protein target. The carbohydrate moiety of isoprimeverose contains galacturonic acid, which may play a role in its uptake by mammalian cells. The hydroxyl group on the sugar molecule may also play a role in this process. Isoprimeverose can be used as an artificial sweetener because it does not contain any sugars or carbohydrates that can cause tooth decay or other dental problems.

2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU. Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of α-glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form. Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.

1-Deoxy-2-fluoronojirimycin is a glycosylation inhibitor that was synthesized to inhibit the formation of complex carbohydrates. It has been shown to inhibit methyltransferases and glycosylation enzymes in vitro with IC50 values of 0.1 μM, 2 μM, and 4 μM, respectively. This compound has also been shown to inhibit the synthesis of saccharides by targeting sugar moieties. 1-Deoxy-2-fluoronojirimycin inhibits the addition of various sugars at their C1 position with IC50 values ranging from 0.3 μM to 6 μM. The modification of sugars at the C2 position is also inhibited with IC50 values ranging from 3 μM to 10 μM. 1-Deoxy-2-fluoronojirimycin is a custom synthesis that can be ordered in high purity as well as in bulk quantities for research purposes .

N-Acetyl-D-lactosamine heptaacetate is a synthetically produced, fluorinated monosaccharide that is used in the production of glycosylations and polysaccharides. N-Acetyl-D-lactosamine heptaacetate can be custom synthesized to meet your needs. This compound is a high purity product.

2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-Fmoc serine is a protein that belongs to the group of bifunctional glycosides. It is used in recombinant virus production as a component of the viral coat protein (VP). 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-Fmoc serine binds to tyrosine kinase receptors and inhibits their activity. This inhibition prevents cell adhesion and migration and can cause tumor regression in some cancers. 2,3,4,6-Tetra-O-acetyl-b-D--glucopyranosyl--Fmoc serine also has antiviral activity due to its ability to inhibit the replication of viruses containing RNA genomes.