APIs para investigación e impurezas

Trandolaprilat is a prodrug of enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor. Trandolaprilat binds to the active site of ACE and inhibits its activity, thereby causing a decrease in the formation of angiotensin II, a potent vasoconstrictor. Trandolaprilat has been shown to be effective in treating congestive heart failure and other cardiac disorders. Trandolaprilat has also been shown to have an effect on energy metabolism, as it inhibits the binding of ATPase to adenosine triphosphate (ATP). This inhibition leads to increased levels of ATP in cells and may be responsible for its cardioprotective effects.

2-Mercaptobenzimidazole is a chemical compound that can be used for the treatment of infectious diseases. It has been shown to have antioxidative properties and inhibit the growth of bacteria. 2-Mercaptobenzimidazole also has an effect on human serum, which may be due to its ability to bind with proteins in serum and form hydrogen bonds. 2-Mercaptobenzimidazole is stable at high temperatures and has been shown as an effective antimicrobial agent against gram positive and gram negative bacteria.

Hydrocortisone 21-Aldehyde (Hydrate

Natriuretic hormone; induces uterine contraction and lactation

11-Fluoro desloratadine is a metabolite of the antihistamine, loratadine. It has shown to be an analytical standard for HPLC, and impurity standard for pharmacopoeia. 11-Fluoro desloratadine is typically synthesized by reacting loratadine with fluorinating reagent such as N-fluorosuccinimide (NFSI) in the presence of a base catalyst such as sodium methoxide. 11-Fluoro desloratadine is also found in breast milk at concentrations of up to 1.2% of total loratadine concentration, which has been attributed to incomplete metabolism or passive transfer from mother to child.