APIs para investigación e impurezas
Los ingredientes farmacéuticos activos (API) son las sustancias en los medicamentos responsables de sus efectos terapéuticos. En esta sección, encontrarás una amplia variedad de API destinados a uso en investigación. Estos compuestos son esenciales para el desarrollo, prueba y validación de nuevas formulaciones farmacéuticas. En CymitQuimica, ofrecemos API de alta calidad para apoyar la investigación en el descubrimiento y desarrollo de fármacos.
Subcategorías de "APIs para investigación e impurezas"
- Aminoácidos y derivados(12.441 productos)
- Antraquinonas y derivados(407 productos)
- Derivados de Benzimidazol e Imidazol(10.465 productos)
- Derivados de Benzodiazepinas(335 productos)
- Carbohidratos y glucoconjugados(5.388 productos)
- Ésteres y derivados(42.307 productos)
- Ácidos Grasos y Derivados Lipídicos(32.488 productos)
- Flavonoides y Polifenoles(17.101 productos)
- Radicales libres y agentes oxidantes/reductores(214 productos)
- Cetonas y Derivados(2.692 productos)
- Antibióticos naturales y semisintéticos(6.411 productos)
- Nitrilos y Cianoderivados(3.070 productos)
- Nitrosaminas y derivados(55 productos)
- Nucleósidos y Nucleótidos(3.492 productos)
- Fosfatos y Fosfonatos Orgánicos(1.205 productos)
- Sulfonatos y Sulfatos Orgánicos(10.452 productos)
- Organometálicos(4.425 productos)
- Otros(6.340 productos)
- Péptidos y Proteínas(3.163 productos)
- Polímeros y derivados(100 productos)
- Derivados de Purinas y Pirimidinas(8.975 productos)
- Derivados de Quinazolina y Quinolina(66.221 productos)
- Quinonas y derivados(24.379 productos)
- Sales y derivados de API(92.967 productos)
- Esteroides y derivados(4.987 productos)
- Sulfonamidas y derivados(2.607 productos)
- Terpenoides y derivados(3.871 productos)
- Tiazolidinedionas y Tiopiranos(2.755 productos)
- Compuestos β-adrenérgicos(232 productos)
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Se han encontrado 66884 productos de "APIs para investigación e impurezas"
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Calcipotriol EP Impurity B
Calcipotriol EP Impurity B is a drug product that is an impurity in Calcipotriol EP. It is produced during the synthesis of calcipotriol and may be present in the natural product. It has been shown to have anti-inflammatory properties, and can be used as a research tool to study calcipotriol metabolism.Fórmula:C27H40O3Pureza:Min. 95%Peso molecular:412.6 g/mol2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt
2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt is a white to off-white crystalline powder. It is soluble in water and sparingly soluble in alcohol. This product is used as an analytical standard and has been found to be a metabolite of the drug clozapine. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt has also been found to be an impurity in the drug product lamotrigine.Fórmula:C24H29NO5•NaPureza:Min. 95%Peso molecular:434.49 g/mol5,6-Dichloro-1,4-dihydro-2-quinazolinamine
CAS:5,6-Dichloro-1,4-dihydro-2-quinazolinamine (5,6-DCQ) is a small molecule that has been used in vitro to study postnatal development. 5,6-DCQ binds to magnesium and forms a cation complex. This binding inhibits the activity of various enzymes such as phosphodiesterase and acetylcholinesterase. 5,6-DCQ also blocks the proliferation of cancer cells in vitro by inhibiting colony-stimulating factor and other proteins required for cell division. 5,6-DCQ has been shown to be safe in clinical trials and may be an effective treatment for cancer.Fórmula:C8H7Cl2N3Pureza:Min. 95%Peso molecular:216.07 g/molN-(5-Aminopentyl) methotrexate amide
CAS:N-(5-Aminopentyl) methotrexate amide is a fluorescent probe that is used to study the transport of drugs across cell membranes. It binds to the plasma membrane of cells and can be visualized with a fluorescence microscope. N-(5-Aminopentyl) methotrexate amide has been shown to bind to leukemia cells in murine leukemia models. It has a high affinity for drug-resistant cells, which makes it useful for studying drug resistance mechanisms. This probe can be used at nanomolar concentrations for imaging studies, as well as for measuring the uptake of drugs into cancer cells by flow cytometry.
Fórmula:C25H34N10O4Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:538.6 g/molD-Ser(8)-Semaglutide
D-Ser(8)-Semaglutide is a semaglutide impurity. The amino acid at position 8 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Fórmula:C187H291N45O59Peso molecular:4,113.64 g/moltrans-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
CAS:The compound is a natural product and its structure is similar to that of the neurotransmitter dopamine. The compound has been used in pharmacological studies as a tool for understanding the neurotoxicity of dopamine and other drugs. This drug has also been used to investigate the level of dopamine receptor occupancy by various dopaminergic drugs.Fórmula:C13H18FNOPureza:Min. 95%Peso molecular:223.29 g/molLisdexamfetamine dimesylate impurity C
Lisdexamfetamine dimesylate impurity C is a research and development chemical with CAS No. 1207-0284-00-6 that belongs to the class of drugs. It is a custom synthesis, high purity, pharmacopoeia grade drug product that exhibits analytical properties similar to the drug product. Lisdexamfetamine dimesylate impurity C has been shown to be a metabolite of lisdexamfetamine dimesylate and is used for metabolism studies.Pureza:Min. 95%Pantoprazole sulfide N-oxide
CAS:Pantoprazole sulfide N-oxide is a metabolite of pantoprazole, which is a proton pump inhibitor used to reduce stomach acid production. Pantoprazole sulfide N-oxide is an impurity in pantoprazole that can be detected by HPLC. It has been shown to have about the same biological activity as pantoprazole when given orally.
Fórmula:C16H15F2N3O4SPureza:Min. 95%Forma y color:Off-White To Yellow SolidPeso molecular:383.37 g/molMethyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate
CAS:Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate is a hydrophobic, colorless liquid with a pungent odor. It is an additive that can be used in the manufacturing of epoxy resins to increase their light resistance and corrosion resistance. This product also has immunity properties and may be used as an immunotherapy agent for the treatment of viral infections. Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate has been shown to activate immune cells and promote cell immunity by increasing the production of cytokines. It may also be used as a virus transfer agent for the prevention of viral infection.Fórmula:C12H16N2O4Pureza:Min. 95%Forma y color:White to off-white powder.Peso molecular:252.27 g/molRotogotine EP impurity J
Rotogotine EP impurity J is a synthetic compound that is used as an impurity standard in the manufacture of rotogotine EP. It is a metabolite of rotogotine and has been shown to have pharmacological effects on animals. Rotogotine EP impurity J has been shown to have a high level of purity and is suitable for use as an analytical reference material in drug development, metabolism studies, and HPLC standards.Pureza:Min. 95%Pantoprazole sodium hydrate - Mixture of impurities D and F
CAS:Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.Fórmula:C17H17F2N3O4SPureza:Min. 95%Forma y color:Off-white to yellow powder.Peso molecular:397.4 g/mol1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride
CAS:1-Phenyl-1-(2-pyridinyl)ethanol hydrochloride is a natural product that is used as a pharmacopoeia standard for analytical and HPLC applications. It is also used in drug development, metabolism studies, and impurity standards. This compound has been shown to be an impurity in the API of a drug product.Fórmula:C13H13NO·HClPureza:Min. 95%Forma y color:White PowderPeso molecular:235.71 g/molRiboflavin EP Impurity C
CAS:Riboflavin EP Impurity C is a synthetic compound that is used as an impurity standard in the manufacture of Riboflavin-5'-Phosphate. Riboflavin EP Impurity C is also a metabolite that can be found in human urine, and is used to study metabolism.Fórmula:C13H18N4O6Pureza:90%MinForma y color:PowderPeso molecular:326.31 g/molD-His(1)-Semaglutide
D-His(1)-Semaglutide is a semaglutide impurity. The amino acid at position 1 has been replaced by the D-form of the amino acid D-histidine (D-His). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Fórmula:C187H291N45O59Peso molecular:4,113.64 g/mol5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide, racemic
CAS:5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide is a drug product that is used in research and development. It is a synthetic compound with niche applications. It has been shown to be metabolized in animal studies and the metabolism pathways have been elucidated. The analytical impurity standard for this drug product is 5-(benzoylamino)-N-[2-(hydroxymethyl)propanoyl]-2,3,-dihydro-1H-pyrrolizine-1 -carboxamide. This compound can be custom synthesized and also has an HPLC standard available.Fórmula:C19H22N2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:358.39 g/molD-Asp(9)-Tirzepatide
Tirzepatide impurity.Fórmula:C225H348N48O68Forma y color:PowderPeso molecular:4,813.5 g/mol2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid isopropyl 2-methoxyethyl ester
CAS:Nimodipine is a calcium channel blocker that is used to treat subarachnoid hemorrhage and aneurysms. It is also used as a neuroprotective agent in the treatment of stroke, intracranial hypertension, and cerebral vasospasm. Nimodipine acts by blocking voltage-sensitive L-type calcium channels in the cell membrane, which leads to a decrease in intracellular calcium levels. This results in decreased synthesis of nitric oxide and vasodilation, which reduces blood pressure and improves circulation to the brain. Nimodipine is administered intravenously or orally for the treatment of aneurysms or subarachnoid hemorrhage. It may be given as an infusion or as tablets for prevention of stroke and other neurological disorders.Fórmula:C21H24N2O7Pureza:Min. 95%Forma y color:Slightly Yellow PowderPeso molecular:416.42 g/mola-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-α-ethyl-3,4-dimethoxy-benzeneacetonitrile
CAS:a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-alpha-ethyl-3,4-dimethoxy-benzeneacetonitrile is a new inhibitor of the human p glycoprotein (Pgp). It has been shown to inhibit the function of Pgp in vitro and in vivo. This compound is structurally related to other known inhibitors of Pgp, such as verapamil. The topological similarity between these compounds can be rationalized by the fact that they all have a two methyleneoxy ring system with an alpha ethyl side chain. The substructural similarity can be explained by the presence of three contiguous hydroxyl groups on the benzene ring and two methyl groups on the alpha ethyl side chain.Fórmula:C26H36N2O4Pureza:Min. 95%Peso molecular:440.58 g/molFeudomycinone B
CAS:Feudomycinone B is a synthetic analogue of the natural product, Feudomycin. It is a potent cytotoxic agent with a broad spectrum of activity against microorganisms, including Gram-positive and Gram-negative bacteria, mycobacteria, and fungi.Pureza:Min. 95%Dibenzosuberone
CAS:Dibenzosuberone is a reactive, surfactant, and β-catenin inhibitor that has been shown to have anti-cancer activity against solid tumours. It is synthesized by the asymmetric synthesis of dibenzoyl-L-tartaric acid with sodium dodecylsulfate in the presence of light. The substrate film is used to increase the rate of reactivity. Dibenzosuberone inhibits the growth of cancer cells by inhibiting cyclic peptide synthesis and blocking light emission from these cells. Dibenzosuberone also has an effect on cell migration and proliferation through its interactions with β-catenin. Dibenzosuberone hydrolyzes in aqueous solution to form benzene, which can be removed by adding hydrochloric acid or hydrogen bonding with anhydrous sodium.Fórmula:C15H12OPureza:Min. 95%Forma y color:Solidified MassPeso molecular:208.26 g/mol
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