APIs para investigación e impurezas
Los ingredientes farmacéuticos activos (API) son las sustancias en los medicamentos responsables de sus efectos terapéuticos. En esta sección, encontrarás una amplia variedad de API destinados a uso en investigación. Estos compuestos son esenciales para el desarrollo, prueba y validación de nuevas formulaciones farmacéuticas. En CymitQuimica, ofrecemos API de alta calidad para apoyar la investigación en el descubrimiento y desarrollo de fármacos.
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- Antibióticos naturales y semisintéticos(6.409 productos)
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Se han encontrado 66870 productos de "APIs para investigación e impurezas"
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(S)-5-((tert-Butylamino)methyl)-3-(3-fluoro-(4-morpholinyl)phenyl)oxazolidin-2-one
CAS:(S)-5-((tert-Butylamino)methyl)-3-(3-fluoro-(4-morpholinyl)phenyl)oxazolidin-2-one is a drug product with CAS No. 1215006-08-8, which is a metabolite of Fluoxetine. It is an impurity standard for Fluoxetine and has been used as a reference compound in metabolism studies. (S)-5-((tert-Butylamino)methyl)-3-(3-fluoro-(4-morpholinyl)phenyl)oxazolidin-2-one is also an analytical reagent that can be used to calibrate HPLC systems.Fórmula:C18H26FN3O3Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:351.42 g/mol5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.Fórmula:C15H12BrO3NPureza:Min. 95%Peso molecular:334.16 g/molGliclazide impurity F
CAS:Gliclazide is a sulfonylurea drug that is used to treat type 2 diabetes. The impurity F, which is an impurity standard, can be synthesized by reacting 1-chloro-2,6-difluoroaniline with sodium methoxide in methanol. It is also an API impurity found in the synthesis of gliclazide and can be custom synthesized for research and development purposes. Gliclazide impurity F has a CAS number of 1076198-18-9 and the molecular formula C8H4ClF3NOS. This product has a purity of >99% and is classified as synthetic. It has been shown to have pharmacopoeia activity and can also be used for niche applications such as drug development.Fórmula:C15H21N3O3SPureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:323.41 g/mol5-Aminolevulinic acid hydrochloride
CAS:Photodynamic Therapy of Actinic Keratosis. Porphobilinogen synthase substrate that produces endogenous porphyrins useful for sensitizing cells in photodynamic therapy. Intermediate in heme and chlorophyll biosynthesis. Estimation of 5-aminolevulinic acid dehydratase. PBG formed in the assay is determined spectrophotometrically with Ehrlich's reagent. Used in Porphyrin test for differentiation of Haemophilus species. Enzymes that convert ALA to porphyrins in the biosynthesis of hemin (X factor) are not produced by H. influenzae, H.aegyptius and H. canis. These enzymes are produced by H. parainfluenzae, H. parahaemolyticus, H. gallinarum, H. parasuis, H. parahaemolyticus and H. aphrophilus. A positive reaction is indicated by an orange-red fluorescence.Fórmula:C5H10ClNO3Pureza:Min. 98.0 Area-%Peso molecular:167.59 g/mol4-Keto 13-cis-retinoic acid
CAS:4-Keto 13-cis-retinoic acid is a synthetic retinoid that was first synthesized in the 1970s. It is used for the treatment of ichthyosiform erythroderma and other skin diseases. 4-Keto 13-cis-retinoic acid binds to the retinoic acid receptor, which may be responsible for its effects on epidermal growth factor and cytosolic calcium. Treatment with 4-keto 13-cis-retinoic acid has been shown to inhibit the proliferation of hl-60 cells and squamous carcinoma cells in vitro, as well as reduce tumor size and metastasis in vivo. >>ENDFórmula:C20H26O3Pureza:Min. 95%Forma y color:PowderPeso molecular:314.42 g/molAcetaminophen acetate
CAS:Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.Fórmula:C10H11NO3Pureza:Min. 95%Forma y color:White PowderPeso molecular:193.2 g/molD-Asp(9)-Semaglutide
D-Asp(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the D-form of the amino acid D-aspartic acid (D-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.
Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molSemaglutide Impurity 59
D-Arg(28)-Semaglutide is a semaglutide impurity. The amino acid at position 28 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.
Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molD-Ser32-Tirzepatide
Please enquire for more information about D-Ser32-Tirzepatide including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C225H348N48O68Peso molecular:4,813.5 g/molDesfluoro atorvastatin
CAS:Desfluoro atorvastatin is a crystalline polymorph of atorvastatin that has been shown to have improved flowrate and dissolution profile compared with the conventional form. Desfluoro atorvastatin is synthesized by adding a fluorine atom to a specific position in the molecule. The synthesis procedure includes chromatographic purification and analysis of impurities, which are then eliminated by diode laser irradiation. Impurities may also be eliminated through hydrogenation or recrystallization.Fórmula:C33H36N2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:540.65 g/mol5-Methyl Zolpidem
CAS:5-Methyl Zolpidem is a zolpidem tartrate that is used for the treatment of insomnia and as a sedative. It is an intermediate in the synthesis of zolpidem tartrate, which is synthesized from 5-methyl-1-(4-methoxybenzoyl)-1H-benzo[d]imidazole with potassium t-butoxide. The synthesis starts with the conversion of 5-methyl-1-(4-methoxybenzoyl)-1H-benzo[d]imidazole to 1-(4'-methylphenyl) benzene by reaction with methyl iodide followed by hydrolysis of the ester group to form 1-(4'-methylphenyl) benzene. The next step involves a nucleophilic substitution reaction using potassium t-butoxide to produce 1-(4'-methylphenyl) benzene t-butoxide, followed by reaction with methanolFórmula:C19H21N3OPureza:Min. 95%Forma y color:White/Off-White SolidPeso molecular:307.39 g/mol2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid ethyl ester hydrobromide
CAS:2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid ethyl ester hydrobromide is a drug development impurity that belongs to the group of API impurities. It is an impurity standard for HPLC and also appears as a metabolite in animal studies. This compound has been shown to have a high purity and can be used as a custom synthesis or analytical standard. 2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid ethyl ester hydrobromide is also an impurity in the drug product called "NOVOQUINOL". The compound has been found to be an intermediate in metabolism studies.Fórmula:C12H14BrCl2N3O2Pureza:Min. 95%Forma y color:PowderPeso molecular:383.07 g/molAmikacin EP Impurity A
CAS:Amikacin EP Impurity A is a metabolite of amikacin. It is a white crystalline substance with a molecular weight of 269.5. Amikacin EP Impurity A is found in the urine and bile of individuals who have been administered amikacin. It has been shown to be pharmacologically active, inhibiting bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication.Fórmula:C22H43N5O13Pureza:Min. 95%Peso molecular:585.6 g/molN,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride
CAS:N,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride is an analytical standard used to determine the purity of a drug product. It is also used as a pharmacopoeia standard and in research and development. N,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride is synthesized from 4-chlorobenzaldehyde and 1,2,3-triazole. It has been shown that this chemical can be metabolized by CYP1A2, CYP2D6, CYP3A4, and CYP3A5 enzyme systems. This chemical has not been found to have any impurities.Fórmula:C22H17Cl3N6•(HCl)xPureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:471.77 g/mol2-Hydroxybenzimidazole
CAS:2-Hydroxybenzimidazole is a benzimidazole compound that is used in the treatment of nervous system diseases. It has been shown to have anti-inflammatory properties and can be used in the treatment of syncytial virus infection. 2-Hydroxybenzimidazole inhibits the production of reactive oxygen species and nitric oxide, which are involved in neurodegenerative disorders. The mechanism of action for 2-Hydroxybenzimidazole involves the formation of hydrogen bonds with hydroxyl groups on proteins. It also has been shown to reduce locomotor activity and increase sleep time in mice, which may be due to inhibition of acetylcholine release from cholinergic neurons.Fórmula:C7H6N2OPureza:Min. 97.5 Area-%Forma y color:Off-White PowderPeso molecular:134.14 g/molAmoxicillin trihydrate impurity N
Amoxicillin trihydrate impurity N is a drug product that is an impurity in amoxicillin trihydrate. It is a natural, API impurity, which has been synthesized and tested for use as an impurity standard for HPLC analysis of amoxicillin trihydrate. The CAS number for Amoxicillin trihydrate impurity N is 592-84-1.Pureza:Min. 95%Lisdexamfetamine dimesylate impurity C
Lisdexamfetamine dimesylate impurity C is a drug product that is an analytical standard. It is a synthetic impurity found in the drug Lisdexamfetamine Dimesylate, which is used for the treatment of ADHD and narcolepsy. Lisdexamfetamine Dimesylate Impurity C has been shown to be metabolized through oxidation by cytochrome P450 enzymes and conjugation with glucuronic acid. The impurity has been shown to have no effect on the pharmacological activity of the parent compound.
Pureza:Min. 95%Methyl 2,2-dithienylglycolate
CAS:Intermediate for tiotropium bromide synthesisFórmula:C11H10O3S2Pureza:Min. 95%Forma y color:White PowderPeso molecular:254.33 g/mol2,3,4-Trimethoxybenzyl alcohol
CAS:2,3,4-Trimethoxybenzyl alcohol is a photooxidant that is used in pharmaceutical formulations. It has a catalytic effect on the photooxidation of trifluoroacetic acid and is used for the production of fluoroquinolones. It can also be used to produce other pharmaceutical compounds such as antibiotics and anti-cancer drugs. 2,3,4-Trimethoxybenzyl alcohol is found in small quantities in many natural products such as fruits and vegetables. It has been shown to have potential impurities including 4-methoxybenzaldehyde and selectivity modifiers.Fórmula:C10H14O4Pureza:Min 96.5%Forma y color:Clear LiquidPeso molecular:198.22 g/mol(1R,4S)-N-Desmethyl sertraline hydrochloride
CAS:Sertraline metaboliteFórmula:C16H16Cl3NPureza:Min. 95%Forma y color:PowderPeso molecular:328.66 g/mol
