APIs para investigación e impurezas
Los ingredientes farmacéuticos activos (API) son las sustancias en los medicamentos responsables de sus efectos terapéuticos. En esta sección, encontrarás una amplia variedad de API destinados a uso en investigación. Estos compuestos son esenciales para el desarrollo, prueba y validación de nuevas formulaciones farmacéuticas. En CymitQuimica, ofrecemos API de alta calidad para apoyar la investigación en el descubrimiento y desarrollo de fármacos.
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Se han encontrado 66870 productos de "APIs para investigación e impurezas"
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2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
CAS:2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a synthetic building block which can undergo reaction with nucleophilic carbon species to afford C-ribosides (via the corresponding hemiacetal). Treatment of 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone with stronger reducing agents, such as sodium borohydride, affords ring opened products with a stereo-defined poly-oxygenated carbon chain backbone.Fórmula:C26H26O5Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:418.48 g/molD-Phe(6)-Semaglutide
D-Phe(6)-Semaglutide is a semaglutide impurity. The amino acid at position 6 has been replaced by the D-form of the amino acid D-phenylalanine (D-Phe). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molUdp-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine
CAS:UDP-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine is a potent inhibitor of tumor growth and has been used in medicinal research for its potential anticancer properties. It works by targeting kinases that are involved in the regulation of cell growth and survival, inducing apoptosis (programmed cell death) in cancer cells. UDP-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine is an analog of UDP-N-acetylglucosamine, which is a protein precursor found in human urine. This inhibitor has been shown to be effective against various types of cancer, including breast, lung, and prostate cancer. Additionally, it has been found to inhibit the activity of Chinese hamster ovary cells that produce proteins for therapeutic use. Overall, UDP-3-O[R-3-hydroxymyristoyl]-N-acetylglucosamine holds great promise as a potential anticancer
Fórmula:C31H53N3O19P2Pureza:Min. 95%Peso molecular:833.7 g/molDesethyl amiodarone hydrochloride
CAS:Amiodarone hydrochloride is an antiarrhythmic drug that belongs to the class of chromatographic agents. It is a prodrug, which is metabolized to amiodarone in vivo. Amiodarone has been shown to be effective in preventing ventricular fibrillation and malignant arrhythmias. Amiodarone prevents the onset of cardiac arrhythmia by prolonging the action potential duration and refractory period, which stabilizes the cell membrane potential during depolarization. The drug also inhibits the release of calcium ions from the sarcoplasmic reticulum, thereby reducing excitability and preventing re-entry into a fibrillating state. Amiodarone is used for the treatment of atrial fibrillation, ventricular tachycardia, and chronic heart failure.Fórmula:C23H25I2NO3•HClPureza:Min. 95%Forma y color:PowderPeso molecular:653.72 g/molD-Ser(11)-Semaglutide
D-Ser(11)-Semaglutide is a semaglutide impurity. The amino acid at position 11 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molN-(((5S)-3-(4-(4-Morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl) acetamide
CAS:N-(((5S)-3-(4-(4-Morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl) acetamide is an impurity of the antibiotic linezolid. It is a contaminant that can be found in urine and blood samples. N-(((5S)-3-(4-(4-Morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl) acetamide has been shown to be amyloidogenic, meaning it can form plaques in the brain and lead to Alzheimer's disease.Fórmula:C16H21N3O4Pureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:319.36 g/molAztreonam impurity D
CAS:Aztreonam impurity D is a metabolite of aztreonam. Aztreonam impurity D is an impurity standard for the pharmacopoeia and API industry, as well as for drug development and research. It has been shown that this compound inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Aztreonam impurity D also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Fórmula:C13H17N5O5SPureza:Min. 95 Area-%Forma y color:PowderPeso molecular:355.37 g/molN-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide sodium salt
CAS:2-Nitroacetamide sodium salt is an impurity of the drug N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide, a synthetic chemotherapeutic agent for the treatment of cancers. This compound has been shown to have metabolism studies and natural properties. It has a CAS number of 112251-56-6 and is found in the pharmacopoeia. 2-Nitroacetamide sodium salt is a custom synthesis that can be used as a reference standard for HPLC analysis. It can also be used as a drug product or metabolite in drug development.
Fórmula:C12H18N3O4SNaPureza:Min. 95%Forma y color:PowderPeso molecular:323.34 g/molN-(2-Amino-4-thiazolyl)acetyl mirabegron
CAS:N-(2-Amino-4-thiazolyl)acetyl mirabegron is a research chemical that belongs to the category of drugs. It is custom synthesized and purified through analytical methods. N-(2-Amino-4-thiazolyl)acetyl mirabegron has been studied for its metabolism in vivo, including its pharmacokinetics and pharmacodynamics. This drug product is a metabolite of mirabegron, an agent used for the treatment of overactive bladder syndrome (OAB). The metabolite is also present in urine and plasma samples.
Fórmula:C26H28N6O3S2Pureza:Min. 95%Peso molecular:536.7 g/molOxytocin
CAS:Natriuretic hormone; induces uterine contraction and lactation
Fórmula:C43H66N12O12S2Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:1,007.19 g/molSemaglutide Impurity 29 (beta-Asp-9)
Beta-Asp-(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the beta-aspartic acid (also known as isoaspartic, isoAsp, β-Asp or beta-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Fórmula:C187H291N45O59Peso molecular:4,113.64 g/mol4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(tetrazol-5-yl)phenyl]phenyl]methyl imidazole-5-carboxylate [4-[2-(tetrazol-5-yl)phenyl] phenyl]methyl
CAS:4-[2-(Tetrazol-5-yl)phenyl] phenyl]methyl is a metabolite of the drug product 4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(tetrazol-5-yl)phenyl]phenyl]methyl imidazole-5-carboxylate. 4-[2-(Tetrazol-5-yl)phenyl] phenyl]methyl is a yellowish solid with a melting point of 128°C and a molecular weight of 246.8 g/mol. The impurity standard for 4-[2-(Tetrazol-5-yl)phenyl] phenyl]methyl is available in the form of an analytical grade, HPLC standard, or pharmacopoeia grade.Fórmula:C38H36N10O3Pureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:680.76 g/mol1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester
CAS:1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester is a creatine kinase inhibitor that blocks the synthesis of creatine phosphate, which is an important energy source for muscle contraction. Creatine kinase inhibitors are used in the treatment of congestive heart failure and myocardial infarct. They also have vasodilatory effects on blood vessels and can be used to treat hypertension. The elimination rate of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester depends on its formulation: solid dispersions have a half life of about 3 hours whereas orally administered doses have a half life of about 8 hours.Fórmula:C17H18N2O6Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:346.33 g/molFluticasone furoate impurity F
Fluticasone furoate impurity F is a synthetic, high-purity, pharmacopoeia grade drug product. It has been developed for research and development purposes only. Impurity standard: Fluticasone furoate impurity F is a metabolite of fluticasone furoate. Synthetic: Fluticasone furoate impurity F is a synthetic compound that has been custom synthesized to meet your requirements. Drug Development: Fluticasone furoate impurity F has been developed as a drug product to be used in the development of new drugs. Metabolism Studies: Fluticasone furoate impurity F can be used in metabolism studies and analytical determinations.END>>Pureza:Min. 95%2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol
CAS:2- (4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol is a pharmaceutical intermediate that is a potent inhibitor of the enzyme acetylcholinesterase. It has been used as a photolytic probe in chromatographic experiments. 2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol has been synthesized by the reaction of 4-(benzo[b]thieno[2,3d]thiazol)piperazine with ethanol. The impurities present are quantified and their concentrations are reported as percent weight/volume (% w/v). Impurities that may be found in this product include acetonitrile, orthophosphate, and linearity.Fórmula:C19H21N3OSPureza:Min. 95%Forma y color:PowderPeso molecular:339.46 g/mol3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide
CAS:3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide is a synthetic drug product. It is not found in natural products and it has no pharmacopoeia name. 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide is an impurity standard for the manufacture of pharmaceuticals. It is also used as a research and development reagent and analytical standard. 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide has not been evaluated by the FDA as a food additive, but it has been evaluated by the European Union as a flavoring agent.Fórmula:C8H13N5OS2Pureza:Min. 95%Forma y color:White PowderPeso molecular:259.35 g/mol2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt
2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt is a white to off-white crystalline powder. It is soluble in water and sparingly soluble in alcohol. This product is used as an analytical standard and has been found to be a metabolite of the drug clozapine. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid sodium salt has also been found to be an impurity in the drug product lamotrigine.Fórmula:C24H29NO5•NaPureza:Min. 95%Peso molecular:434.49 g/mol(S,E)-N-(1-(3-Methylbut-1-enylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
CAS:R-N-(1-(3-methylbut-1-enyl)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide is a drug product that is used for the treatment of bacterial infections. The compound is an impurity in the synthesis of other compounds and is also used as an analytical standard. It is synthesized from commercially available starting materials and through custom synthesis. R-N-(1-(3-methylbut-1-enyl)-1--oxo--3--phenylpropan--2--yl)pyrazine--2--carboxamide has been shown to be metabolized by CYP450 enzymes, which are responsible for the metabolism of many drugs. R-(1-(3Methylbut 1Enylamino)-1Oxo 3Phenylpropan 2Yl)Pyrazine 2Carboxamide has not been evaluated as a drug product and therefore does notFórmula:C19H22N4O2Pureza:Min. 95%Peso molecular:338.4 g/mol
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