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APIs para investigación e impurezas

APIs para investigación e impurezas

Los ingredientes farmacéuticos activos (API) son las sustancias en los medicamentos responsables de sus efectos terapéuticos. En esta sección, encontrarás una amplia variedad de API destinados a uso en investigación. Estos compuestos son esenciales para el desarrollo, prueba y validación de nuevas formulaciones farmacéuticas. En CymitQuimica, ofrecemos API de alta calidad para apoyar la investigación en el descubrimiento y desarrollo de fármacos.

Subcategorías de "APIs para investigación e impurezas"

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  • 2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole

    CAS:
    2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole (CAS No. 168167-42-8) is a synthetic compound that is used as an analytical reference standard for HPLC. It is also used in the study of drug metabolism, and it has been shown to induce natural oxidation in vitro. 2-[(4-Chloro-3-methylpyridinium)methylsulfinyl]-1Hbenzimidazole is an impurity found in pharmaceutical products that are synthesized from 1-(2,4,6trichlorophenyl)-3-[(4chloromethyl)phenyl]urea.
    Fórmula:C14H12ClN3OS
    Pureza:Min. 95 Area-%
    Forma y color:Brown Powder
    Peso molecular:305.78 g/mol

    Ref: 3D-IC21226

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  • Lysolecithin

    CAS:

    Lysolecithin is an analog of the phospholipid lecithin that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cell signaling and regulation. Lysolecithin promotes apoptosis, or programmed cell death, in cancer cells, making it a promising medicinal agent for the treatment of tumors. Studies have also shown that lysolecithin can inhibit protein kinase activity in human urine and inhibit the growth of cancer cells in Chinese hamsters. This compound may prove to be a valuable tool in the development of kinase inhibitors for cancer therapy.

    Fórmula:C24H50NO7P
    Pureza:Min. 95%
    Peso molecular:495.6 g/mol

    Ref: 3D-PAA86327

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  • Doxorubicin Impurity 15

    CAS:

    Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.

    Fórmula:C31H38BrNO11
    Pureza:Min. 95%
    Peso molecular:680.54 g/mol

    Ref: 3D-ID163220

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  • 6-o-Desmethyl moxonidine

    CAS:

    6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.

    Fórmula:C8H10ClN5O
    Pureza:Min. 95%
    Peso molecular:227.65 g/mol

    Ref: 3D-CPA45733

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  • Mch-1 antagonist 1

    CAS:

    Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.

    Fórmula:C25H26N4O2
    Pureza:Min. 95%
    Peso molecular:414.5 g/mol

    Ref: 3D-PRB82568

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  • Xanthoxin

    CAS:

    Xanthoxin is a medicinal compound with potent anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in cancer cells. Xanthoxin has been tested in various cancer cell lines, including Chinese and human cells, and has demonstrated strong inhibitory effects on the tumor cycle. This compound works by inhibiting kinases and other proteins involved in cancer cell growth and proliferation. Xanthoxin is also known to be an inhibitor of certain urinary proteins that are associated with cancer progression. Overall, Xanthoxin shows great potential as a natural product for the development of novel anticancer therapies.

    Fórmula:C15H22O3
    Pureza:Min. 95%
    Peso molecular:250.33 g/mol

    Ref: 3D-IAA06607

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  • N-4,5[Acetylamino)methyl]desmopressin


    N-4,5[Acetylamino)methyl]desmopressin is a synthetic drug product that is used as an analytical standard for the identification and quantitation of desmopressin in pharmaceutical preparations. It is also used as an impurity standard for HPLC analysis. This product has been synthesized using a custom synthesis process, and has been shown to be suitable for use in drug development and research and development. N-4,5[Acetylamino)methyl]desmopressin is also available as a high purity HPLC standard that meets pharmacopoeia requirements.

    Pureza:Min. 95%

    Ref: 3D-IA173214

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  • Levofloxacin carboxylic acid

    CAS:

    Levofloxacin is a synthetic molecule with an asymmetric carbon atom in its heterocycle. It is synthesized by reacting chloroform with 2-fluoro-5-nitrobenzaldehyde, which reacts further with sodium hydroxide and hydrochloric acid to form the levofloxacin carboxylic acid. Impurities can be found in the reaction product due to chlorine atoms that are formed during the synthesis. The amount of impurities present in the final product can be determined using a titration method or through HPLC analysis. Levofloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.

    Fórmula:C13H9F2NO4
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:281.21 g/mol

    Ref: 3D-IL24882

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  • o-Desmethyl venlafaxine N-dimer

    CAS:

    o-Desmethyl venlafaxine N-dimer is a metabolite of venlafaxine that has been identified in human plasma. It is a white to off-white crystalline powder with a melting point of about 175°C. The purity of the product is more than 98%. It is soluble in methanol and ethanol, but insoluble in water. The o-desmethyl venlafaxine N-dimer was developed as an analytical reference standard for use in HPLC analysis of venlafaxine and its metabolites and impurities.

    Fórmula:C32H48N2O4
    Pureza:Min. 95%
    Peso molecular:524.73 g/mol

    Ref: 3D-MXB54561

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  • Regadenoson Impurity 28

    CAS:

    Regadenoson Impurity 28 is an analytical standard and research and development impurity. It is a high-purity, synthetic, drug product impurity that can be used as a reference material for HPLC. This drug impurity is also available in a custom synthesis service. Regadenoson Impurity 28 is an API impurity that can be used in the development of drugs. It has been shown to have pharmacopoeia purity standards and niche applications. Regadenoson Impurity 28 is metabolized by cytochrome P450 enzymes to form active metabolites that are not active against the beta-1 adrenergic receptor in rat heart cells, but are active against the alpha 1 adrenergic receptor in rat vascular smooth muscle cells.

    Fórmula:C10H14N6O3
    Pureza:Min. 95%
    Peso molecular:266.26 g/mol

    Ref: 3D-IR181469

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  • o-Desphenyl sofosbuvir

    CAS:

    o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.

    Fórmula:C16H25FN3O9P
    Pureza:Min. 95%
    Peso molecular:453.36 g/mol

    Ref: 3D-IZB33582

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  • (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt

    CAS:

    (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2-methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5-dihydroxy- 6-heptenoic acid sodium salt is a synthetic drug product. It is an impurity standard in the synthesis of Metabolism studies. The CAS number is 1714147-50-8 and the chemical name is (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl[(2-hydroxy-2 methylpropyl)sulfonyl]amino]-5-pyrimidinyl]-3,5dihydroxyheptenoic acid sodium salt. The molecular weight is 781

    Fórmula:C25H33FN3NaO7S
    Pureza:Min. 95%
    Peso molecular:561.6 g/mol

    Ref: 3D-IF156830

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  • 4-Methanesulfonyloxybutanol

    CAS:

    4-Methanesulfonyloxybutanol is a chemical substance with the molecular formula CH3SO2CH(CH2OH)CH2OH. It is used as an intermediate in the synthesis of 4-methanesulfonyloxybutanol, which is a potent inhibitor of busulfan-induced leukopenia and myelosuppression. This substance has been shown to be highly effective in preventing busulfan-induced side effects when administered intravenously. 4-Methanesulfonyloxybutanol is chemically synthesized by intramolecular alkylation of butanol, followed by hydrolysis. The reaction product can be detected using an ionization detector in conjunction with gas chromatography. This product is an alkylation agent that reacts with polypropylene to produce polypropylene glycols.

    Fórmula:C5H12O4S
    Pureza:Min. 95%
    Forma y color:Liquid
    Peso molecular:168.21 g/mol

    Ref: 3D-IM145656

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  • 9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione

    CAS:

    9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is a metabolite of the drug 9-(1,3-Dioxolan-2-ylmethyl)-1,3,9 dihydrobenzo[g]pteridine. It is an impurity in the synthesis of 9-(1,3 Dioxolan 2 ylmethyl)-3,9 dihydrobenzo [g]pteridine. The purity of this compound is > 99%, with a melting point range of 233 to 235 °C and a molecular weight of 244.24 g/mol. It is soluble in methanol and acetonitrile. This compound has been characterized by IR spectroscopy (ATR), 1H NMR (400 MHz) spectroscopy (CDCl 3 ), and mass spectrometry (HRMS

    Fórmula:C11H14N4O4
    Pureza:Min. 95%
    Peso molecular:266.25 g/mol

    Ref: 3D-ZWB28918

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  • N-Desbispropyl-N-pentyl-2-methyl ropinirole

    CAS:

    N-Desbispropyl-N-pentyl-2-methyl ropinirole is an analytical reference standard. This product is a high purity, drug development, and API impurity. It is a CAS No. 249622-60-4 and has a niche, drug product, and impurity standard. This item is for Research and Development, High purity, Drug development, API impurity, HPLC standard, CAS No. 249622-60-4, niche, drug product, Impurity standard, Metabolite, pharmacopoeia Custom synthesis of natural or synthetic origin.

    Fórmula:C16H24N2O
    Pureza:Min. 95%
    Peso molecular:260.37 g/mol

    Ref: 3D-ZJA62260

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  • Pantoprazole sulfone N-oxide

    CAS:

    Pantoprazole sulfone N-oxide is a prodrug that is converted to the active form pantoprazole in the stomach where it inhibits gastric acid secretion. Pantoprazole sulfone N-oxide has been shown to be genotoxic, and can cause polyvinyl chloride to degrade when stored together. Reconstituted solution of this drug should be used within 24 hours after reconstitution, as the chemical stability of this drug decreases rapidly. Validation studies have been conducted on different analytical methods for determining pantoprazole concentrations in reconstituted solutions, and these methods have been harmonized with those published by the United States Pharmacopeia (USP). The pump inhibitor activity of pantoprazole sulfone N-oxide has been demonstrated in dogs, and it is also useful for treating acid reflux disease in humans. Pantoprazole sulfone N-oxide is unstable at high temperatures (>25°C), so should not be refrigerated or

    Fórmula:C16H15F2N3O6S
    Pureza:Min. 95%
    Peso molecular:415.37 g/mol

    Ref: 3D-ID26757

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  • Esomeprazole Impurity Q


    Esomeprazole Impurity Q is a drug product. It is an impurity standard of esomeprazole, CAS No. 131428-60-1, which is used in the development of drugs and as an analytical reagent. It is synthesized from natural materials and has a purity of 99%. The metabolite can be found in animal and human metabolism studies. Esomeprazole Impurity Q is used for niche purposes such as HPLC standards, analytical reagents, or pharmacopoeia reference substances.

    Pureza:Min. 95%

    Ref: 3D-IE177226

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  • (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic Acid 3-Ethyl Ester

    CAS:
    The chemical name for (3R)-3,6-Dihydro-2H-1,4-thiazine-3,5-dicarboxylic acid 3-ethyl ester-d5 is 2-(2-(pyrrolidin-1-yl)ethoxy)ethanol. This compound is a drug product that has been custom synthesized and purified by HPLC. It is an analytical standard and impurity standard for HPLC. The CAS number for this compound is 944115-20-2.
    Fórmula:C8H6D5NO4S
    Pureza:Min. 95%
    Peso molecular:222.27 g/mol

    Ref: 3D-UMB11520

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  • 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole

    CAS:

    2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].

    Fórmula:C15H15N3OS2
    Pureza:Min. 95%
    Peso molecular:317.43 g/mol

    Ref: 3D-IM21229

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  • (E,Z)-Epalrestat methyl ester

    CAS:

    (E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.

    Fórmula:C16H15NO3S2
    Pureza:Min. 95%
    Peso molecular:333.43 g/mol

    Ref: 3D-HCB77570

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