Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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PUMA BH3 Free base
<p>PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of</p>Formule :C130H206N42O45SDegré de pureté :96.64%Couleur et forme :SolidMasse moléculaire :3109.35Eltrombopag
CAS :<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Formule :C25H22N4O4Degré de pureté :99.27%Couleur et forme :Orange To Red SolidMasse moléculaire :442.47EF24
CAS :<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Formule :C19H15F2NODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :311.33Pantoprazole sodium
CAS :<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Formule :C16H14F2N3NaO4SDegré de pureté :96.92% - 99.81%Couleur et forme :White To Off-White SolidMasse moléculaire :405.358-Bromo-cAMP sodium salt
CAS :<p>8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.</p>Formule :C10H10BrN5NaO6PDegré de pureté :98% - 99.94%Couleur et forme :Off-White PowderMasse moléculaire :430.08Sclareol
CAS :<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Formule :C20H36O2Degré de pureté :99.58% - 99.97%Couleur et forme :White Fine PowderMasse moléculaire :308.5Pyrogallol
CAS :<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Formule :C6H6O3Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :126.11Avitinib
CAS :<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Formule :C26H26FN7O2Degré de pureté :99.81% - >99.99%Couleur et forme :SolidMasse moléculaire :487.53BI 2536
CAS :<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Formule :C28H39N7O3Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :521.65DD1
CAS :<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Formule :C16H14N2O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :282.29Ixabepilone
CAS :<p>Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor.</p>Formule :C27H42N2O5SDegré de pureté :98% - 99.50%Couleur et forme :SolidMasse moléculaire :506.7Tenilsetam
CAS :<p>Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.</p>Formule :C8H10N2OSDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :182.24D-Saccharic acid 1,4-lactone hydrate
CAS :<p>D-Saccharic acid 1,4-lactone hydrate inhibits β-glucuronidase (IC50=48.4 μM); has anticarcinogenic, detoxifying, antioxidant traits.</p>Formule :C17H20ClN3ODegré de pureté :99.49% - ≥98%Couleur et forme :SolidMasse moléculaire :317.81BI-6C9
CAS :<p>BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.</p>Formule :C23H25N3O4S2Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :471.59DL-Buthionine-(S,R)-sulfoximine
CAS :<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Formule :C8H18N2O3SDegré de pureté :98% - 99.64%Couleur et forme :White Fine PowderMasse moléculaire :222.31LY-411575
CAS :<p>LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage.</p>Formule :C26H23F2N3O4Degré de pureté :97.03% - 99.38%Couleur et forme :SolidMasse moléculaire :479.48RG7112
CAS :<p>RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.</p>Formule :C38H48Cl2N4O4SDegré de pureté :99.66% - 99.9%Couleur et forme :SolidMasse moléculaire :727.78TCPOBOP
CAS :<p>TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.</p>Formule :C16H8Cl4N2O2Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :402.06Orantinib
CAS :<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formule :C18H18N2O3Degré de pureté :98.92% - 99.52%Couleur et forme :SolidMasse moléculaire :310.35Mycophenolate Mofetil
CAS :<p>Mycophenolate Mofetil (TM-MMF), is an immunosuppressive agent, 2-morpholinoethyl ester of MPA, and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).</p>Formule :C23H31NO7Degré de pureté :98.27% - 99.85%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :433.49(Rac)-Idroxioleic acid
CAS :<p>(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.</p>Formule :C18H34O3Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :298.46OsMundacetone
CAS :<p>OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.</p>Formule :C10H10O3Degré de pureté :99.59% - ≥95%Couleur et forme :SolidMasse moléculaire :178.18OUL35
CAS :<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Formule :C14H12N2O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :256.26PHA-665752
CAS :<p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.</p>Formule :C32H34Cl2N4O4SDegré de pureté :97.05% - 98.82%Couleur et forme :SolidMasse moléculaire :641.61K-Ras(G12C) inhibitor 12
CAS :<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Formule :C15H17ClIN3O3Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :449.67Saquinavir
CAS :<p>Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.</p>Formule :C38H50N6O5Degré de pureté :99.50% - >99.99%Couleur et forme :SolidMasse moléculaire :670.84Paederosidic acid
CAS :<p>Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.</p>Formule :C18H24O12SDegré de pureté :98% - 99.56%Couleur et forme :SolidMasse moléculaire :464.44Droxinostat
CAS :<p>Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3</p>Formule :C11H14ClNO3Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :243.695'-Methylthioadenosine
CAS :<p>5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.</p>Formule :C11H15N5O3SDegré de pureté :99.32% - 99.34%Couleur et forme :SolidMasse moléculaire :297.33LDN-57444
CAS :<p>LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .</p>Formule :C17H11Cl3N2O3Degré de pureté :97.8% - 99.87%Couleur et forme :SolidMasse moléculaire :397.64Palomid 529
CAS :<p>Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.</p>Formule :C24H22O6Degré de pureté :98.40% - 98.59%Couleur et forme :SolidMasse moléculaire :406.43Ulinastatin
CAS :<p>Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.</p>Formule :C13H16O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.10994DMU-212
CAS :<p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>Formule :C18H20O4Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :300.35Carfilzomib
CAS :<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Formule :C40H57N5O7Degré de pureté :99.6% - 99.84%Couleur et forme :SolidMasse moléculaire :719.91Capmatinib 2HCl.H2O
CAS :<p>Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.</p>Formule :C23H21Cl2FN6O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :503.36Tandutinib
CAS :<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Formule :C31H42N6O4Degré de pureté :99.45% - ≥98%Couleur et forme :White SolidMasse moléculaire :562.7Quinidine sulfate dihydrate
CAS :<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Formule :C40H54N4O10SDegré de pureté :99.85%Couleur et forme :White To Light Yellow Crystal PowdeMasse moléculaire :782.9GS-444217
CAS :<p>GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).</p>Formule :C23H21N7ODegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :411.46β-Ionone
CAS :<p>β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic</p>Formule :C13H20ODegré de pureté :98.52%Couleur et forme :Colourless Liquid OilyMasse moléculaire :192.3Cinchonine monohydrochloride hydrate
CAS :<p>Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.</p>Formule :C19H25ClN2O2Couleur et forme :SolidMasse moléculaire :348.87(20S)-Protopanaxatriol
CAS :<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Formule :C30H52O4Degré de pureté :95% - 99%Couleur et forme :SolidMasse moléculaire :476.73TM5441
CAS :<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formule :C21H17ClN2O6Degré de pureté :97.62% - 99.09%Couleur et forme :SolidMasse moléculaire :428.82Benzoylpaeoniflorin
CAS :<p>1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.</p>Formule :C30H32O12Degré de pureté :95.86% - 97.28%Couleur et forme :SolidMasse moléculaire :584.57Eprenetapopt
CAS :<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Formule :C10H17NO3Degré de pureté :98.75% - 99.57%Couleur et forme :SolidMasse moléculaire :199.25LASSBio-1135
CAS :<p>LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.</p>Formule :C18H14N4Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :286.33Epoxomicin
CAS :<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Formule :C28H50N4O7Degré de pureté :98.65% - 98.86%Couleur et forme :White To Off-White SolidMasse moléculaire :554.72Helichrysetin
CAS :<p>Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.</p>Formule :C16H14O5Degré de pureté :96.32% - ≥95%Couleur et forme :SolidMasse moléculaire :286.28JQ-1 (carboxylic acid)
CAS :<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Formule :C19H17ClN4O2SDegré de pureté :99.14% - 99.9%Couleur et forme :SolidMasse moléculaire :400.88Concanavalin A
CAS :<p>Concanavalin A is a natural product, a phytoalexin. Concanavalin A has antitumor activity and can also induce acute liver injury. Cost effective and quality assured.</p>Formule :C23H32N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :104-112 kDaFlavokawain B
CAS :<p>Flavokawain B inhibits NO and PGE2, causes oxidative stress, and induces apoptosis, with potential for treating prostate cancer.</p>Formule :C17H16O4Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :284.313'-Hydroxypterostilbene
CAS :<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Formule :C16H16O4Degré de pureté :98.25% - 99.19%Couleur et forme :SolidMasse moléculaire :272.3Sertaconazole
CAS :<p>Sertaconazole is a broad-spectrum antifungal.</p>Formule :C20H15Cl3N2OSDegré de pureté :99.483%Couleur et forme :SolidMasse moléculaire :437.77RAF265
CAS :<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Formule :C24H16F6N6ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :518.41Meloxicam sodium
CAS :<p>Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].</p>Formule :C14H12N3NaO4S2Couleur et forme :SolidMasse moléculaire :373.38DAPK Substrate Peptide acetate
<p>DAPK Substrate Peptide acetate is a death-associated protein kinase (DAPK, Km = 9 μM) peptide substrate.</p>Formule :C70H115N25O17Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :1578.82RRX-001
CAS :<p>RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity</p>Formule :C5H6BrN3O5Degré de pureté :99.91% - ≥95%Couleur et forme :SolidMasse moléculaire :268.02PS-1145
CAS :<p>PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.</p>Formule :C17H11ClN4ODegré de pureté :98.81% - >99.99%Couleur et forme :SolidMasse moléculaire :322.75ONC212
CAS :<p>ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.</p>Formule :C24H23F3N4ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :440.46Ligustrazine
CAS :<p>Ligustrazine (Tetramethylpyrazine), a natural compound isolated from Chuan Xiong shows anti-inflammation, antioxidant, antiplatelet, and antiapoptosis effects.</p>Formule :C8H12N2Degré de pureté :99.91% - >99.99%Couleur et forme :White Crystals Or PowderMasse moléculaire :136.19Deguelin
CAS :<p>Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.</p>Formule :C23H22O6Degré de pureté :96.39% - 99.29%Couleur et forme :SolidMasse moléculaire :394.42Amuvatinib
CAS :<p>Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.</p>Formule :C23H21N5O3SDegré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :447.51Decursin
CAS :<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Formule :C19H20O5Degré de pureté :97.22% - 99.84%Couleur et forme :SolidMasse moléculaire :328.36Siremadlin
CAS :<p>Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.</p>Formule :C26H24Cl2N6O4Degré de pureté :99.30% - 99.76%Couleur et forme :SolidMasse moléculaire :555.41Mycophenolic acid sodium
CAS :<p>Mycophenolic acid sodium inhibits IMPDH with EC50 of 0.24 μM, has antiviral, immunosuppressive, antiangiogenic, and antitumor properties.</p>Formule :C17H19NaO6Couleur et forme :SolidMasse moléculaire :342.323Tofacitinib Citrate
CAS :<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Formule :C22H28N6O8Degré de pureté :99.19% - 99.75%Couleur et forme :SolidMasse moléculaire :504.49Itanapraced
CAS :<p>Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).</p>Formule :C16H11Cl2FO2Degré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :325.16Desmethylanethol trithione
CAS :<p>Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.</p>Formule :C9H6OS3Degré de pureté :98.05% - 98.41%Couleur et forme :SolidMasse moléculaire :226.34Dimethyl malonate
CAS :<p>Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.</p>Formule :C5H8O4Degré de pureté :≥95%Couleur et forme :LiquidMasse moléculaire :132.11Vildagliptin dihydrate
CAS :<p>Vildagliptin dihydrate: potent, selective DPP-IV inhibitor with 3.5 nM IC50, high oral bioavailability, effective against hyperglycemia.</p>Formule :C17H29N3O4Couleur et forme :SolidMasse moléculaire :339.4362-Bromohexadecanoic acid
CAS :<p>2-Bromohexadecanoic acid (2-BP) is a PPARδ agonist, and a palmitoylation inhibitor, inhibiting DHHC-mediated palmitoylation. Cost-effective and quality-assured.</p>Formule :C16H31BrO2Degré de pureté :97% - 98.3%Couleur et forme :White Crystalline PowderMasse moléculaire :335.32Chelerythrine
CAS :<p>1.</p>Formule :C21H18NO4Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :348.37SRT 2183
CAS :<p>SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 μM).</p>Formule :C27H24N4O2SDegré de pureté :97.86%Couleur et forme :SolidMasse moléculaire :468.57Picroside II
CAS :<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Formule :C23H28O13Degré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :512.46Thapsigargin
CAS :<p>Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.</p>Formule :C34H50O12Degré de pureté :99.07% - 99.3%Couleur et forme :Colourless FilmMasse moléculaire :650.75WYE-354
CAS :<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Formule :C24H29N7O5Degré de pureté :97.86% - 99.61%Couleur et forme :SolidMasse moléculaire :495.53Fedratinib
CAS :<p>Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.</p>Formule :C27H36N6O3SDegré de pureté :97.31% - 99.96%Couleur et forme :SolidMasse moléculaire :524.68CAY10404
CAS :<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Formule :C17H12F3NO3SDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :367.34RA375
CAS :<p>RA375 inhibits RPN13, enhances UPR, ROS, apoptosis, and is 10x more potent against cancer than RA190 due to nitro rings and chloroacetamide.</p>Formule :C30H25ClN4O7Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :588.99ONO-8130
CAS :<p>ONO-8130 is an orally available antagonist of EP1 receptor.</p>Formule :C25H28N2O5S2Degré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :500.63Verbascoside
CAS :<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Formule :C29H36O15Degré de pureté :97.46% - 99.55%Couleur et forme :SolidMasse moléculaire :624.59Mitoxantrone diacetate
CAS :<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Formule :C26H36N4O10Couleur et forme :SolidMasse moléculaire :564.592ASTX660
CAS :<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Formule :C30H42FN5O3Degré de pureté :98.33% - 99.85%Couleur et forme :SolidMasse moléculaire :539.68AZD-7648
CAS :<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Formule :C18H20N8O2Degré de pureté :99.03% - 99.85%Couleur et forme :SolidMasse moléculaire :380.4Prexasertib Mesylate Hydrate
CAS :<p>Prexasertib Mesylate Hydrate is a potent CHK1 inhibitor (IC50<1nM), also inhibits CHK2, RSK1, induces DNA breaks, apoptosis, and has anti-tumor effects.</p>Formule :C19H25N7O6SCouleur et forme :SolidMasse moléculaire :479.51INCB-057643
CAS :<p>INCB057643 is a potent, selective and orally bioavailable BET inhibitor.</p>Formule :C20H21N3O5SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :415.46Fasentin
CAS :<p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>Formule :C11H9ClF3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :279.64Bardoxolone Methyl
CAS :<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Formule :C32H43NO4Degré de pureté :97.81% - 99.09%Couleur et forme :SolidMasse moléculaire :505.691-(1-Naphthyl) piperazine hydrochloride
CAS :<p>1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple</p>Formule :C14H17ClN2Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :248.75Flavokawain A
CAS :<p>NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.</p>Formule :C18H18O5Degré de pureté :97.1% - 99.72%Couleur et forme :SolidMasse moléculaire :314.332TASIN-1
CAS :<p>TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).</p>Formule :C18H28N2O3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :352.49PHYTOSPHINGOSINE
CAS :<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Formule :C18H39NO3Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :317.51SKLB-163
CAS :<p>SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.</p>Formule :C18H16ClN3O2S2Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :405.92Ibuprofen Lysine
CAS :<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Formule :C19H32N2O4Degré de pureté :99.26%Couleur et forme :CoaMasse moléculaire :352.47MCB-613
CAS :<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Formule :C20H20N2ODegré de pureté :98.17% - 99.754%Couleur et forme :SolidMasse moléculaire :304.39Gomisin N
CAS :<p>Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.</p>Formule :C23H28O6Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :400.46PFI-1
CAS :<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formule :C16H17N3O4SDegré de pureté :98.74% - 99.19%Couleur et forme :SolidMasse moléculaire :347.39BI-847325
CAS :<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Formule :C29H28N4O2Degré de pureté :97.13% - 97.54%Couleur et forme :SolidMasse moléculaire :464.56BRD3308
CAS :<p>BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.</p>Formule :C15H14FN3O2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :287.29UCF 101
CAS :<p>UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.</p>Formule :C27H17N3O5SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :495.514-Oxofenretinide
CAS :<p>4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.</p>Formule :C26H31NO3Degré de pureté :96.89%Couleur et forme :SolidMasse moléculaire :405.53
