Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(135 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6225 produits trouvés pour "Apoptose"
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Madecassoside
CAS :Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activitiesFormule :C48H78O20Degré de pureté :99.46% - 99.85%Couleur et forme :White PowderMasse moléculaire :975.12Ref: TM-T2813
10mg49,00€1mL*10mM (DMSO)49,00€25mg84,00€50mg120,00€100mg178,00€200mg289,00€500mg485,00€PFK-158
CAS :PFK-158 is an effective and specific inhibitor PFKFB3.Formule :C18H11F3N2ODegré de pureté :95.49% - 99.16%Couleur et forme :SolidMasse moléculaire :328.29Ref: TM-T3105
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg90,00€25mg170,00€50mg259,00€100mg409,00€BMS-1
CAS :BMS-1 is a PD-1/PD-L1 inhibitor and immunomodulator; it targets the CD274 gene product, PD-L1, linked to tumor evasion and higher mortality.
Formule :C29H33NO5Degré de pureté :99.40% - 99.81%Couleur et forme :SolidMasse moléculaire :475.58Z-FA-FMK
CAS :Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Formule :C21H23FN2O4Degré de pureté :98.84% - 99.68%Couleur et forme :SolidMasse moléculaire :386.42Zinc Protoporphyrin
CAS :Zinc Protoporphyrin is an oral HO-1 inhibitor that reduces PG's protection against H2O2 and has anti-cancer properties.Formule :C34H32N4O4ZnDegré de pureté :95.43% - 99.27%Couleur et forme :SolidMasse moléculaire :626.02LY-294002 hydrochloride
CAS :LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.Formule :C19H17NO3·HClDegré de pureté :99.95% - 99.98%Couleur et forme :SolidMasse moléculaire :343.81Capmatinib xHCl
CAS :Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50Formule :C23H18ClFN6ODegré de pureté :98.62% - 99.81%Couleur et forme :SolidMasse moléculaire :448.89PI-1840
CAS :PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formule :C22H26N4O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :394.472'-OMe-Guanosine
CAS :2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.Formule :C11H15N5O5Degré de pureté :99.93%Couleur et forme :White SolidMasse moléculaire :297.27Linderalactone
CAS :1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.Formule :C15H16O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T5S1897
1mg43,00€5mg84,00€1mL*10mM (DMSO)102,00€10mg119,00€25mg197,00€50mg294,00€100mg437,00€Pantoprazole
CAS :Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormule :C16H15F2N3O4SDegré de pureté :97.16% - 99.63%Couleur et forme :Almost White SolidMasse moléculaire :383.37ATH686
CAS :ATH686 is an potent and selective Inhibitor of FLT3.Formule :C25H28F3N7O2Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :515.53Ref: TM-T7673
1mg101,00€5mg245,00€1mL*10mM (DMSO)268,00€10mg394,00€25mg670,00€50mg888,00€100mg1.224,00€GW779439X
CAS :GW779439X is an inhibitor of CDK.Formule :C22H21F3N8Degré de pureté :97.87%Couleur et forme :SolidMasse moléculaire :454.45Ref: TM-T8866
1mg58,00€2mg82,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg178,00€25mg404,00€50mg592,00€100mg845,00€VER-50589
CAS :VER-50589 is a potent HSP90 inhibitor.Formule :C19H17ClN2O5Degré de pureté :99.96% - >99.99%Couleur et forme :SolidMasse moléculaire :388.8Ref: TM-T2258
1mg39,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg150,00€25mg250,00€50mg384,00€100mg557,00€200mg787,00€FR 180204
CAS :FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Formule :C18H13N7Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :327.34Ref: TM-T1956
1mg40,00€2mg52,00€5mg81,00€1mL*10mM (DMSO)89,00€10mg131,00€25mg210,00€50mg314,00€100mg470,00€MSC 2032964A
CAS :MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.
Formule :C16H13F3N6ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :362.31Ref: TM-T33514
1mg84,00€2mg97,00€5mg158,00€10mg240,00€25mg393,00€50mg560,00€100mg753,00€200mg1.035,00€CHS-828
CAS :CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Formule :C19H22ClN5ODegré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :371.86LW6
CAS :LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formule :C26H29NO5Degré de pureté :98.1% - 98.22%Couleur et forme :SolidMasse moléculaire :435.51Ref: TM-T3494
2mg44,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg94,00€25mg173,00€50mg281,00€100mg424,00€500mg888,00€Wogonin
CAS :Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formule :C16H12O5Degré de pureté :98% - 99.8%Couleur et forme :Yellow CrystalMasse moléculaire :284.26Ref: TM-T2933
5mg34,00€10mg42,00€1mL*10mM (DMSO)52,00€25mg59,00€50mg92,00€100mg131,00€200mg178,00€500mg309,00€Formosanin C
CAS :Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.Formule :C51H82O20Degré de pureté :98.98% - >99.99%Couleur et forme :SolidMasse moléculaire :1015.18Cyasterone
CAS :Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormule :C29H44O8Degré de pureté :99.32% - 99.70%Couleur et forme :SolidMasse moléculaire :520.65Stattic
CAS :Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.Formule :C8H5NO4SDegré de pureté :98.32% - 99.76%Couleur et forme :SolidMasse moléculaire :211.19Ref: TM-T6308
5mg35,00€10mg51,00€1mL*10mM (DMSO)55,00€25mg85,00€50mg124,00€100mg187,00€200mg279,00€500mg465,00€Pifithrin-α hydrobromide
CAS :Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formule :C16H18N2OS·HBrDegré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :367.3Genistein
CAS :Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formule :C15H10O5Degré de pureté :98.22% - 99.64%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24(1E,6E)-Bis(demethoxy)curcumin
CAS :(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formule :C19H16O4Degré de pureté :97.45% - 98.39%Couleur et forme :SolidMasse moléculaire :308.33Ref: TM-T6S1688
5mg42,00€1mL*10mM (DMSO)49,00€10mg52,00€25mg81,00€50mg105,00€100mg152,00€500mg353,00€AZ 628
CAS :AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.Formule :C27H25N5O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :451.52SGI-1027
CAS :SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.52Ref: TM-T1904
5mg58,00€1mL*10mM (DMSO)74,00€10mg94,00€25mg163,00€50mg296,00€100mg467,00€500mg1.035,00€Chelidonine
CAS :Chelidonine from Chelidonium majus triggers HeLa cell apoptosis, may reverse MDR, boost chemotherapeutics against leukemia, and inhibit cancer cell metastasis.Formule :C20H19NO5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :353.37Rotenone
CAS :Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formule :C23H22O6Degré de pureté :89.58% - 99.88%Couleur et forme :Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Masse moléculaire :394.42Wedelolactone
CAS :Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formule :C16H10O7Degré de pureté :98.07% - 99.87%Couleur et forme :SolidMasse moléculaire :314.25Ref: TM-T3384
1mg34,00€1mL*10mM (DMSO)50,00€5mg71,00€10mg109,00€25mg175,00€50mg314,00€100mg414,00€500mg954,00€Goserelin acetate
CAS :Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
Formule :C61H88N18O16Degré de pureté :99.77% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :1329.46PIK-75
CAS :PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formule :C16H14BrN5O4SDegré de pureté :98.52% - >99.99%Couleur et forme :SolidMasse moléculaire :452.28Levomenol
CAS :Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.Formule :C15H26ODegré de pureté :96.01%Couleur et forme :Clear To Yellowish LiquidMasse moléculaire :222.37PKR-IN-C16
CAS :PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.Formule :C13H8N4OSDegré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :268.29Ref: TM-T16550
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)105,00€10mg130,00€25mg260,00€50mg409,00€100mg605,00€Neferine
CAS :Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formule :C38H44N2O6Degré de pureté :98.81% - 99.65%Couleur et forme :SolidMasse moléculaire :624.77Momordin Ic
CAS :Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunctionFormule :C41H64O13Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :764.94Isoalantolactone
CAS :Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formule :C15H20O2Degré de pureté :99.75% - 99.94%Couleur et forme :SolidMasse moléculaire :232.32Zoledronic acid monohydrate
CAS :Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formule :C5H12N2O8P2Degré de pureté :99.91%Couleur et forme :White To Off-White PowderMasse moléculaire :290.1Toddaculin
CAS :Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of theFormule :C16H18O4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :274.31Infigratinib
CAS :Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 andFormule :C26H31Cl2N7O3Degré de pureté :98% - 98.97%Couleur et forme :SolidMasse moléculaire :560.48Ref: TM-T1975
5mg44,00€1mL*10mM (DMSO)48,00€10mg57,00€25mg84,00€50mg90,00€100mg144,00€200mg259,00€500mg437,00€Glycochenodeoxycholic Acid
CAS :Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid.Formule :C26H43NO5Degré de pureté :97% - 99.97%Couleur et forme :SolidMasse moléculaire :449.62Ref: TM-T4588
5mg34,00€10mg49,00€1mL*10mM (DMSO)54,00€25mg79,00€50mg104,00€100mg154,00€200mg220,00€500mg374,00€Telekin
CAS :Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.Formule :C15H20O3Degré de pureté :99.86% - 99.97%Couleur et forme :SolidMasse moléculaire :248.32AT7519
CAS :AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.Formule :C16H17Cl2N5O2Degré de pureté :98.88% - 99.65%Couleur et forme :SolidMasse moléculaire :382.24Malabaricone B
CAS :Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.Formule :C21H26O4Degré de pureté :99.84% - 99.91%Couleur et forme :SolidMasse moléculaire :342.43(E/Z)-TG003
CAS :(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.Formule :C13H15NO2SDegré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :249.33Ref: TM-T1901
2mg39,00€5mg50,00€1mL*10mM (DMSO)50,00€10mg87,00€25mg156,00€50mg258,00€100mg378,00€200mg537,00€ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47m-3M3FBS
CAS :m-3M3FBS is a phospholipase C (PLC) activator.Formule :C16H16F3NO2SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :343.36Polygalacin D
CAS :Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormule :C57H92O27Degré de pureté :98.95% - ≥98%Couleur et forme :SolidMasse moléculaire :1209.4Choline
CAS :Choline is a ubiquitous water soluble nutrient, often associated with the B vitaminsFormule :C5H15NO2Degré de pureté :85% - ≥98%Couleur et forme :LiquidMasse moléculaire :121.18MPTP hydrochloride
CAS :MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.Formule :C12H16ClNDegré de pureté :96.35% - >99.99%Couleur et forme :SolidMasse moléculaire :209.72Ref: TM-T4081
5mg34,00€1mL*10mM (DMSO)50,00€10mg52,00€25mg80,00€50mg131,00€100mg177,00€200mg281,00€500mg447,00€CHR-6494 TFA
CAS :CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formule :C18H17F3N6O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :406.36Ref: TM-T9521
1mg60,00€5mg122,00€1mL*10mM (DMSO)142,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€Obatoclax Mesylate
CAS :Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormule :C20H19N3O·CH4O3SDegré de pureté :99.58% - 99.88%Couleur et forme :SolidMasse moléculaire :413.49CCT007093
CAS :CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Formule :C15H12OS2Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :272.39Isocurcumenol
CAS :1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).Formule :C15H22O2Degré de pureté :99.29% - ≥95%Couleur et forme :SolidMasse moléculaire :234.33Ref: TM-T5S0543
1mg66,00€1mL*10mM (DMSO)147,00€5mg160,00€10mg250,00€25mg425,00€50mg610,00€100mg853,00€200mg1.144,00€Neobavaisoflavone
CAS :Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.Formule :C20H18O4Degré de pureté :99.31% - 99.92%Couleur et forme :SolidMasse moléculaire :322.35Ref: TM-T6S0139
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg99,00€50mg144,00€100mg205,00€500mg512,00€RGX-202
CAS :RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.Formule :C4H9N3O2Degré de pureté :99.67% - 99.8%Couleur et forme :SolidMasse moléculaire :131.13PD173955
CAS :PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormule :C21H16Cl2N4OSDegré de pureté :98.52% - 98.99%Couleur et forme :SolidMasse moléculaire :443.35Ref: TM-T3063
2mg35,00€5mg50,00€10mg92,00€1mL*10mM (DMSO)94,00€25mg166,00€50mg248,00€100mg371,00€200mg530,00€Nobiletin
CAS :Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formule :C21H22O8Degré de pureté :98.65% - 99.76%Couleur et forme :SolidMasse moléculaire :402.39Ref: TM-T2834
5mg54,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg117,00€50mg159,00€100mg251,00€200mg371,00€500mg620,00€Bioymifi
CAS :Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.Formule :C22H12BrN3O4SDegré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :494.32Ref: TM-T2065
1mg34,00€2mg47,00€5mg66,00€1mL*10mM (DMSO)79,00€10mg102,00€25mg202,00€50mg364,00€100mg532,00€Oncrasin-1
CAS :Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFormule :C16H12ClNODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :269.73TD52
CAS :TD52, an Erlotinib derivative, is an oral CIP2A cancer inhibitor that disrupts Elk1's attachment to the CIP2A promoter.Formule :C24H16N4Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :360.41Rilmenidine hemifumarate
CAS :Rilmenidine hemifumarate (S-3341 hemifumarate) is an I1 imidazoline receptor and α2-adrenergic receptor agonist that induces autophagy.Formule :C10H16N2OC4H4O4Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :238.28Barasertib-HQPA
CAS :Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56Enzastaurin
CAS :Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formule :C32H29N5O2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :515.6trans-Chalcone
CAS :trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively asFormule :C15H12ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :208.26Chlorfenapyr
CAS :Chlorfenapyr (AC 303630) is a pyrrole insecticide and converts active substances (insecticidal activity) in insects by a multifunctional oxidaseFormule :C15H11BrClF3N2ODegré de pureté :99.33% - 99.49%Couleur et forme :Off-White To Light Brown Powder With An Halide OdorMasse moléculaire :407.61Stavudine sodium
CAS :Stavudine sodium, an oral HIV-1/2 inhibitor, also hinders mtDNA replication, NLRP3 inflammasome, and Amyloid-β autophagy, prompting apoptosis.Formule :C10H11N2NaO4Couleur et forme :SolidMasse moléculaire :246.198Etonogestrel
CAS :Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.Formule :C22H28O2Degré de pureté :99.59% - 99.59%Couleur et forme :SolidMasse moléculaire :324.46Ref: TM-T2567
2mg34,00€5mg50,00€1mL*10mM (DMSO)50,00€10mg70,00€25mg109,00€50mg167,00€100mg310,00€200mg484,00€PRT062607 hydrochloride
CAS :PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formule :C19H23N9O·HClDegré de pureté :97.7% - 99.81%Couleur et forme :SolidMasse moléculaire :429.91Ref: TM-T2696
1mg57,00€2mg81,00€5mg120,00€1mL*10mM (DMSO)132,00€10mg177,00€25mg309,00€50mg475,00€200mg898,00€Piclidenoson
CAS :Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.Formule :C18H19IN6O4Degré de pureté :99.83% - ≥95%Couleur et forme :SolidMasse moléculaire :510.29Ref: TM-T7188
2mg39,00€5mg58,00€1mL*10mM (DMSO)66,00€10mg94,00€25mg173,00€50mg281,00€100mg439,00€200mg628,00€TT-232 TFA(147159-51-1 free base)
CAS :TT2-32 TFA induces a biphasic activation of phosphotyrosine phosphatase activity in human colon tumor cell line, SW620Formule :C47H59F3N10O11S2Degré de pureté :99.27% - 99.8%Couleur et forme :SolidMasse moléculaire :1061.16Ref: TM-T23479L
1mg81,00€2mg105,00€5mg168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€Pyraclostrobin
CAS :Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.Formule :C19H18ClN3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :387.82L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.Formule :C8H19ClN2O3SCouleur et forme :SolidMasse moléculaire :258.77S-99
CAS :S-99 is a high purity chemical that targets ASK and is important for Immunology, Inflammation, Cancer research.Formule :C16H15F3N6ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :364.33cjoc42
CAS :Cjoc42 blocks gankyrin to prevent p53 reduction, aiding cancer prevention and DNA damage response.Formule :C20H21N3O5SDegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :415.46Ref: TM-T27029
1mg60,00€5mg133,00€1mL*10mM (DMSO)152,00€10mg193,00€25mg349,00€50mg522,00€100mg730,00€200mg982,00€Butein
CAS :Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formule :C15H12O5Degré de pureté :98.76% - >99.99%Couleur et forme :SolidMasse moléculaire :272.25Ref: TM-T6427
1mg40,00€2mg52,00€1mL*10mM (DMSO)82,00€5mg84,00€10mg101,00€25mg202,00€50mg326,00€100mg520,00€Fimepinostat
CAS :Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.Formule :C23H24N8O4SDegré de pureté :98.27% - 99.87%Couleur et forme :SolidMasse moléculaire :508.55Ref: TM-T2078
2mg44,00€5mg66,00€1mL*10mM (DMSO)74,00€10mg92,00€25mg172,00€50mg295,00€100mg485,00€500mg1.035,00€Ferrostatin-1
CAS :Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!Formule :C15H22N2O2Degré de pureté :96.1% - 99.68%Couleur et forme :SolidMasse moléculaire :262.35Rosiglitazone potassium
CAS :Rosiglitazone (BRL 49653) is an oral PPARγ agonist (EC50: 60 nM), TRPC5 activator (EC50: 30 μM), and TRPM3 inhibitor, used in obesity and diabetes research.Formule :C18H18KN3O3SCouleur et forme :SolidMasse moléculaire :395.52Vandetanib trifluoroacetate
CAS :Vandetanib trifluoroacetate: oral VEGFR2/KDR inhibitor, IC50=40nM, also blocks VEGFR3/FLT4 (110nM) and EGFR/HER1 (500nM).Formule :C24H25BrF4N4O4Couleur et forme :SolidMasse moléculaire :589.386Sulindac sodium
CAS :Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.Formule :C20H16FNaO3SCouleur et forme :SolidMasse moléculaire :378.39Chloropyramine
CAS :Chloropyramine: H1 antagonist for allergies like conjunctivitis, asthma; has anti-breast cancer properties.Formule :C16H20ClN3Couleur et forme :SolidMasse moléculaire :289.8YUM70
CAS :YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.Formule :C21H19ClN2O4Degré de pureté :97.25%Couleur et forme :SolidMasse moléculaire :398.84Ref: TM-T8901
1mg46,00€1mL*10mM (DMSO)90,00€5mg92,00€10mg128,00€25mg250,00€50mg369,00€100mg525,00€200mg710,00€CHIR-124
CAS :CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.Formule :C23H22ClN5ODegré de pureté :96.33% - 98.35%Couleur et forme :SolidMasse moléculaire :419.91Ref: TM-T6350
1mg39,00€2mg49,00€5mg77,00€1mL*10mM (DMSO)82,00€10mg99,00€25mg161,00€50mg227,00€100mg339,00€LYN-1604 hydrochloride
CAS :LYN-1604 HCl activates ULK1 (EC50: 18.94 nM); key for studying TNBC.Formule :C33H44Cl3N3O2Couleur et forme :SolidMasse moléculaire :621.08Pemetrexed disodium hemipenta hydrate
CAS :Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formule :C20H21N5O6·2NaH2ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :518.43AX-024
CAS :AX-024 is an oral inhibitor of TCR-Nck with a 1 nM IC50, targeting SH3 domains, has low toxicity, is potent and selective, and reduces key cytokines.Formule :C21H22FNO2Couleur et forme :SolidMasse moléculaire :339.4Fosbretabulin Disodium
CAS :Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).Formule :C18H19O8P·2NaDegré de pureté :97.43% - 99.96%Couleur et forme :White SolidMasse moléculaire :440.29PF-3758309 dihydrochloride
PF-3758309 dihydrochloride is a potent PAK4 inhibitor (Kd = 2.7 nM, Ki = 18.7 nM), oral, ATP-competitive; blocks cell growth, induces apoptosis.Formule :C25H32Cl2N8OSCouleur et forme :SolidMasse moléculaire :563.55Pioglitazone potassium
CAS :Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.Formule :C19H19KN2O3SCouleur et forme :SolidMasse moléculaire :394.53Atezolizumab
CAS :Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Degré de pureté :95.10% - 99.3% （SEC-HPLC）Couleur et forme :LiquidMasse moléculaire :144.6 kDa8-Prenylnaringenin
CAS :8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,Formule :C20H20O5Degré de pureté :98.26% - 99.46%Couleur et forme :SolidMasse moléculaire :340.37Ref: TM-TN1146
1mg137,00€5mg334,00€1mL*10mM (DMSO)414,00€10mg494,00€25mg782,00€50mg1.054,00€100mg1.414,00€Y-27632 HCl hydrate
CAS :Y-27632 HCl hydrate is an orally effective, ATP-competitive ROCK1/ROCK2 inhibitor (Ki=220 nM/300 nM) that inhibits caspase-3 and suppresses stem cell apoptosis.Formule :C14H25Cl2N3O2Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :338.27BV6
CAS :BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formule :C70H96N10O8Degré de pureté :97.46% - 99.82%Couleur et forme :SolidMasse moléculaire :1205.57Ref: TM-T6428
1mg49,00€2mg64,00€5mg89,00€10mg144,00€1mL*10mM (DMSO)178,00€25mg285,00€50mg537,00€100mg767,00€Temsirolimus
CAS :Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formule :C56H87NO16Degré de pureté :97.76% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :1030.29Inecalcitol
CAS :Inecalcitol is a unique vitamin D3 analog that induces apoptosis and has anticancer activity.Cost-effective and quality-assured.Formule :C26H40O3Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :400.59TCS-PIM-1-4a
CAS :SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formule :C11H6F3NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :273.23Dihydrorotenone
CAS :Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.Formule :C23H24O6Degré de pureté :98.98% - 99.58%Couleur et forme :SolidMasse moléculaire :396.43Ref: TM-TN1586
1mg92,00€5mg250,00€1mL*10mM (DMSO)256,00€10mg399,00€25mg660,00€50mg888,00€100mg1.198,00€C646
CAS :C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formule :C24H19N3O6Degré de pureté :98% - 99.21%Couleur et forme :SolidMasse moléculaire :445.42Ref: TM-T2452
2mg46,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg92,00€25mg185,00€50mg360,00€100mg532,00€500mg1.144,00€Flurbiprofen Axetil
CAS :Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formule :C19H19FO4Degré de pureté :97.58% - 98%Couleur et forme :SolidMasse moléculaire :330.35
