Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5599 produits trouvés pour "Apoptose"
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MDK-4204
CAS :<p>MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively.</p>Formule :C31H29FN4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :492.59RC-33 HCl
CAS :<p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>Formule :C21H28ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.91SMBA2
CAS :<p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>Formule :C8H16N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :168.24Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Formule :C29H34N2O15Couleur et forme :SolidMasse moléculaire :650.58VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Formule :C26H20Cl2F3N5O3S2Couleur et forme :SolidMasse moléculaire :642.5D44
CAS :<p>D44 is a Plasmodium FKBPs inhibitor.</p>Formule :C16H16N4OSCouleur et forme :SolidMasse moléculaire :312.39QTX125
CAS :<p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>Formule :C23H19N3O5Couleur et forme :SolidMasse moléculaire :417.41Apoptotic agent-1
CAS :<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Formule :C12H6ClN5O2SCouleur et forme :SolidMasse moléculaire :319.73PI3Kδ-IN-11
CAS :<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Formule :C27H21N5OCouleur et forme :SolidMasse moléculaire :431.49LG190178
CAS :<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Formule :C28H42O5Couleur et forme :SolidMasse moléculaire :458.63PI3K-IN-33
CAS :<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Formule :C23H21BrN6O2Couleur et forme :SolidMasse moléculaire :493.36Fomesafen
CAS :<p>Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).</p>Formule :C15H10ClF3N2O6SDegré de pureté :99.91% - 99.93%Couleur et forme :White Crystalline Solid Fomesafen Is A White Crystalline Solid Used As An HerbicideMasse moléculaire :438.76TrxR inhibitor D9
CAS :<p>TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).</p>Formule :C25H20AuOPSCouleur et forme :SolidMasse moléculaire :596.43Ki23057
CAS :<p>Ki23057, a FGFR2 inhibitor, boosts chemo effects in resistant gastric cancer, may work with SN38/PTX/VP16, enhancing apoptosis via ERCC1/p53 synergy.</p>Formule :C30H35N3O4Couleur et forme :SolidMasse moléculaire :501.62K145
CAS :<p>K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.</p>Formule :C18H24N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.46Berubicin HCl
CAS :<p>Berubicin hydrochloride, a brain-penetrating anthracycline, disrupts DNA replication and repair by inhibiting topoisomerase II.</p>Formule :C34H36ClNO11Couleur et forme :SolidMasse moléculaire :670.1STAT3-IN-3
CAS :<p>STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.</p>Formule :C27H26BrN3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :600.48CYD-2-11
CAS :<p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>Formule :C22H18N2O3Couleur et forme :SolidMasse moléculaire :358.39CMLD012612
CAS :<p>CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).</p>Formule :C31H33N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :559.61Darinaparsin
CAS :<p>Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.</p>Formule :C12H22AsN3O6SCouleur et forme :SolidMasse moléculaire :411.31HIOC
CAS :<p>TrkB agonist; shields neurons & retinas; crosses blood-brain & retinal barriers.</p>Formule :C16H19N3O3Couleur et forme :SolidMasse moléculaire :301.34Mcl-1 inhibitor 10
CAS :<p>Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.</p>Formule :C21H15F3O4Couleur et forme :SolidMasse moléculaire :388.34MMP-9-IN-3
CAS :<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Formule :C29H25N3O4Couleur et forme :SolidMasse moléculaire :479.53Dimethoate
CAS :<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Formule :C5H12NO3PS2Degré de pureté :99.74% - 99.91%Couleur et forme :White Crystalline SolidMasse moléculaire :229.26AG311
CAS :<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Formule :C17H15N5SCouleur et forme :SolidMasse moléculaire :321.4MG-262
CAS :<p>MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].</p>Formule :C25H42BN3O6Couleur et forme :SolidMasse moléculaire :491.43M199
CAS :<p>M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.</p>Formule :C17H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.343-(3-Phenoxybenzyl)amino-β-carboline
CAS :<p>3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.</p>Formule :C24H19N3OCouleur et forme :SolidMasse moléculaire :365.43Mitochonic Acid 35
CAS :<p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>Formule :C19H19NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.36RIP1 kinase inhibitor 5
CAS :<p>RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) in</p>Formule :C13H17F2NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :257.28DC-5163
CAS :<p>DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.</p>Formule :C18H20ClN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :361.89Tubulin polymerization-IN-26
CAS :<p>Tubulin-IN-26 blocks microtubule formation at colchicine site; IC50 4.64μM; may help in lung cancer study.</p>Formule :C25H23N3O2Couleur et forme :SolidMasse moléculaire :397.47EGFR-IN-51
CAS :<p>EGFR-IN-51 effectively inhibits EGFR and mutations with IC50s of 0.493-461.63 μM; it induces apoptosis in cancer cells.</p>Formule :C21H15N3O2SCouleur et forme :SolidMasse moléculaire :373.43IDO1/TDO-IN-1
CAS :<p>IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.</p>Formule :C21H16O6Couleur et forme :SolidMasse moléculaire :364.35ZMF-10
CAS :<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Formule :C19H17F6N7OCouleur et forme :SolidMasse moléculaire :473.38NSC-639829
CAS :<p>NSC-639829 is an anti-tumor compound that requires a solubilizing agent for dissolution.</p>Formule :C21H20BrN5O3Degré de pureté :99.53% - 99.77%Couleur et forme :SolidMasse moléculaire :470.32Tolbutamide Sodium
CAS :<p>potassium channel blocker</p>Formule :C12H18N2NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.34αβ-Tubulin-IN-1
CAS :<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Formule :C25H19N3O3Couleur et forme :SolidMasse moléculaire :409.44AD-2646
CAS :<p>AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.</p>Formule :C23H40N2O4Couleur et forme :SolidMasse moléculaire :408.57MK-886 sodium salt
CAS :<p>MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.</p>Formule :C27H33ClNNaO2SCouleur et forme :SolidMasse moléculaire :494.06MX107
CAS :<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49IZTZ-1
CAS :<p>IZTZ-1: c-MYC G4 stabilizer, reduces expression, blocks cell cycle, induces apoptosis, inhibits B16 melanoma growth.</p>Formule :C32H35N7SCouleur et forme :SolidMasse moléculaire :549.73AZM475271
CAS :<p>AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)</p>Formule :C23H27ClN4O3Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :442.94MPT0B002
CAS :<p>MPT0B002 is a microtubule inhibitor that acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cells</p>Formule :C19H19NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.36HDAC-IN-51
<p>HDAC-IN-51 is an HDAC inhibitor.</p>Formule :C27H24N4O2Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :436.51Anti-inflammatory agent 54
CAS :<p>Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression</p>Formule :C17H16N2O5Couleur et forme :SolidMasse moléculaire :328.32Thienopyridone
CAS :<p>Thienopyridone: potent, selective PRL phosphatase inhibitor, IC50s: 173/277/128 nM for PRL-1/2/3, induces apoptosis, anticancer.</p>Formule :C13H10N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.3PD-1/PD-L1-IN 6
CAS :<p>Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.</p>Formule :C25H26N2O3Couleur et forme :SolidMasse moléculaire :402.49JS-K
CAS :<p>JS-K is a Nitric oxide donor. It has antiproliferative activity.</p>Formule :C13H16N6O8Couleur et forme :SolidMasse moléculaire :384.3Rooperol
CAS :<p>Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.</p>Formule :C17H14O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.29GL-V9
CAS :<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47Antitumor agent-62
CAS :<p>Antitumor agent-62 releases NO, inhibits cancer cell growth, triggers apoptosis, and halts cell cycle at G2/M.</p>Formule :C21H19N3O9SCouleur et forme :SolidMasse moléculaire :489.46IMM-H004
CAS :<p>IMM-H004 is an effective inhibitor of BV2 microglia activation.</p>Formule :C16H20N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.34E64FC26
CAS :<p>E64FC26 is a PDI family pan-inhibitor with antitumor activity that inhibits PDIA1 and PDIA6 and can be used to study multiple myeloma and pancreatic cancer.</p>Formule :C19H23F3O2Degré de pureté :98.1% - 98.1%Couleur et forme :SolidMasse moléculaire :340.38MBC-11
CAS :<p>MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.</p>Formule :C11H20N3O14P3Degré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :511.21Pim-1 kinase inhibitor 1
CAS :<p>Pim-1 kinase inhibitor 1, IC50 0.11 μM, combats various cancers by inducing apoptosis.</p>Formule :C19H13N3O3Couleur et forme :SolidMasse moléculaire :331.32pan-HER-IN-2
CAS :<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71BTK-IN-24
CAS :<p>BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.</p>Formule :C26H19F4N5O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :509.46CEP-1612
CAS :<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Formule :C35H53N7O7Couleur et forme :SolidMasse moléculaire :683.84Antitumor agent-53
CAS :<p>Antitumor agent-53 hinders tumor growth, induces G2/M cell cycle arrest, and triggers apoptosis via PI3K/AKT in HGC-27 cells.</p>Formule :C24H18FN3OCouleur et forme :SolidMasse moléculaire :383.42PTG-0861
CAS :<p>PTG-0861 is a selective HDAC6 inhibitor with an IC50 of 5.92 nm, promising for hematological cancer research.</p>Formule :C15H9F5N2O3Couleur et forme :SolidMasse moléculaire :360.24Anticancer agent 32
CAS :<p>Compound 2g, an anticancer agent, disrupts cell cycle and induces apoptosis for cancer research.</p>Formule :C24H21F2N5OCouleur et forme :SolidMasse moléculaire :433.45MR2938
CAS :<p>MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.</p>Formule :C21H24N4O3Couleur et forme :SolidMasse moléculaire :380.44AKCI
CAS :<p>AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.</p>Formule :C19H27N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.46Antitumor agent-19
CAS :<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Formule :C24H21ClF3N5ODegré de pureté :98.95% - 99.38%Couleur et forme :SolidMasse moléculaire :487.9YLT205
CAS :<p>YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.</p>Formule :C16H12BrClN4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.78Anticancer agent 55
CAS :<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Formule :C28H21Br2FN2O2Couleur et forme :SolidMasse moléculaire :596.294hGGPPS-IN-2
CAS :<p>hGGPPS-IN-2, a C2-ThP-BP analogue, inhibits hGGPPS, targets MM cells, induces apoptosis, and has anti-myeloma effects.</p>Formule :C20H18FN5O7P2SCouleur et forme :SolidMasse moléculaire :553.4PDPOB
CAS :<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formule :C15H20O5Couleur et forme :SolidMasse moléculaire :280.32RETRA
CAS :<p>RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.</p>Formule :C11H12BrNO3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.25SB 706504
CAS :<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formule :C24H19F3N8ODegré de pureté :98.686%Couleur et forme :SolidMasse moléculaire :492.46EGFR-IN-57
CAS :<p>EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.</p>Formule :C22H15N3O2SCouleur et forme :SolidMasse moléculaire :385.44RET-IN-15
CAS :<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Formule :C27H28N8O2Couleur et forme :SolidMasse moléculaire :496.56Norartocarpetin
CAS :<p>Norartocarpetin inhibits tyrosinase (IC50 0.47μM), prevents browning in food, and fights lung cancer (IC50 22μM) by disrupting cell mechanisms.</p>Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.24SHP2-IN-8
CAS :<p>SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.</p>Formule :C17H21Cl2N5SCouleur et forme :SolidMasse moléculaire :398.35FL3
CAS :<p>FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.</p>Formule :C25H23BrO5Couleur et forme :SolidMasse moléculaire :483.353-ATA
CAS :<p>3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.</p>Formule :C13H10N2SCouleur et forme :SolidMasse moléculaire :226.3BMS-1166 hydrochloride
CAS :<p>"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."</p>Formule :C36H34Cl2N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :677.57GLS1 Inhibitor-4
CAS :<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formule :C29H27F3N10O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.72Butyrolactone I
CAS :<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Formule :C24H24O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.44BMS-200
CAS :BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.Formule :C27H27F2NO6Couleur et forme :SolidMasse moléculaire :499.5IV-23
CAS :<p>IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.</p>Formule :C18H18BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.24OT-82
CAS :<p>OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.</p>Formule :C26H21FN4ODegré de pureté :98.91% - 99.315%Couleur et forme :SolidMasse moléculaire :424.47Nimustine
CAS :<p>Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.</p>Formule :C9H13ClN6O2Couleur et forme :SolidMasse moléculaire :272.69GW837016X
CAS :<p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>Formule :C25H20ClFN4OSCouleur et forme :SolidMasse moléculaire :478.97Anticancer agent 71
CAS :<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Formule :C18H13ClF3N5OCouleur et forme :SolidMasse moléculaire :407.78Antitumor agent-70
CAS :<p>Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.</p>Formule :C21H18N4O2Couleur et forme :SolidMasse moléculaire :358.39AMPK activator 11
CAS :<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Formule :C25H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.45Anti-inflammatory agent 47
CAS :<p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>Formule :C25H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.42PHA-680626
CAS :<p>PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).</p>Formule :C23H26N6O2SCouleur et forme :SolidMasse moléculaire :450.56A-802715
CAS :<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Formule :C16H26N4O3Degré de pureté :96.29%Couleur et forme :SolidMasse moléculaire :322.4SMI-6860766
CAS :<p>SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.</p>Formule :C15H11BrClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.61LG308
CAS :<p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>Formule :C19H17FN2OCouleur et forme :SolidMasse moléculaire :308.35BPTQ
CAS :<p>BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.</p>Formule :C17H16N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.4NF-κB-IN-5
CAS :<p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>Formule :C23H27N3O4Couleur et forme :SolidMasse moléculaire :409.48VEGFR-2-IN-19
CAS :<p>VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.</p>Formule :C21H19N3O2Couleur et forme :SolidMasse moléculaire :345.39Imofinostat
CAS :<p>Imofinostat (MPT0E028) is a selective, orally available pan-HDAC inhibitor with IC₅₀ values of 53.0/106.2/29.5 nM against HDAC1/HDAC2/HDAC6 in HCT116 cells.</p>Formule :C17H16N2O4SCouleur et forme :SolidMasse moléculaire :344.38Tubulin polymerization-IN-22
CAS :<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Formule :C19H16O4Couleur et forme :SolidMasse moléculaire :308.33Ferroptosis inducer-1
CAS :<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Formule :C25H21ClN2O5Couleur et forme :SolidMasse moléculaire :464.9MG-115
CAS :<p>MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.</p>Formule :C25H39N3O5Degré de pureté :97.12%Couleur et forme :White PowderMasse moléculaire :461.59
