Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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CMLD012073
CAS :<p>CMLD012073: Potent eIF4A inhibitor, halts eukaryotic translation; IC50 10 nM in NIH/3T3 cells.</p>Formule :C30H30N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :530.57RET-IN-22
CAS :<p>RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-</p>Formule :C29H31F3N6O4Couleur et forme :SolidMasse moléculaire :584.59Luxeptinib
CAS :<p>Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.</p>Formule :C25H17F4N5O2Couleur et forme :SolidMasse moléculaire :495.43pan-HER-IN-2
CAS :<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71Antitumor agent-55
CAS :<p>Antitumor agent-55 (5q) inhibits PC3 (IC50: 0.91 μM), blocks G1/S phase, induces apoptosis, and halts migration.</p>Formule :C32H34N6O4SCouleur et forme :SolidMasse moléculaire :598.72EGFR/HER2/TS-IN-1
CAS :<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Formule :C24H15N5O4S2Couleur et forme :SolidMasse moléculaire :501.54Bcl-2/Mcl-1-IN-1
CAS :<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Formule :C28H23NO3Couleur et forme :SolidMasse moléculaire :421.49KRAS G12D inhibitor 14
CAS :<p>KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM).</p>Formule :C20H19F3N4OSDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :420.45S130
CAS :<p>S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.</p>Formule :C24H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.47Topoisomerase II inhibitor 9
CAS :<p>Topoisomerase II inhibitor 9: Topo II blocker (IC50: 0.97 μM), DNA intercalator (IC50: 43.51 μM), arrests G2/M in Hep G-2 cells and triggers apoptosis.</p>Formule :C22H17N7O3S2Couleur et forme :SolidMasse moléculaire :491.55CDK6/PIM1-IN-1
CAS :<p>CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.</p>Formule :C25H28FN9Couleur et forme :SolidMasse moléculaire :473.55TPB15
CAS :<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Formule :C18H9Cl4N5OCouleur et forme :SolidMasse moléculaire :453.11CA224
CAS :<p>CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.</p>Formule :C24H22N2OCouleur et forme :SolidMasse moléculaire :354.44Tubulin/MMP-IN-2
CAS :<p>Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.</p>Formule :C40H48NO11PCouleur et forme :SolidMasse moléculaire :749.78BRD0476
CAS :<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Formule :C35H38N4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :674.76IM-54
CAS :<p>IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.</p>Formule :C19H23N3O2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :325.4NSC260594
CAS :<p>NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-</p>Formule :C29H24N6O3Couleur et forme :SolidMasse moléculaire :504.54Tigilanol tiglate
CAS :<p>Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.</p>Formule :C30H42O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :562.65PBENZ-DBRMD
CAS :<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Formule :C11H5Br2NO4Couleur et forme :SolidMasse moléculaire :374.97GW-3333
CAS :<p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>Formule :C22H36N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.55CTX1
CAS :<p>CTX1 is a small molecule activator of p53.</p>Formule :C14H10N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.26CAM 833
CAS :<p>CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.</p>Formule :C26H26ClFN4O5Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :528.96HI5
CAS :<p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.</p>Formule :C42H43N5O8Couleur et forme :SolidMasse moléculaire :745.82HDAC8-IN-3
CAS :<p>HDAC8-IN-3 (P19) inhibits HDAC8 (IC50 9.3 μM), induces leukemic cell apoptosis, and enhances thermal stability.</p>Formule :C18H12N4O3S2Couleur et forme :SolidMasse moléculaire :396.44AK301
CAS :<p>AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).</p>Formule :C19H21ClN2O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :344.84GDP366
CAS :<p>GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.</p>Formule :C20H17N5OSDegré de pureté :98.78% - 99.84%Couleur et forme :SolidMasse moléculaire :375.45Mcl1-IN-9
CAS :<p>Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.</p>Formule :C37H39ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :639.18LOM612
CAS :<p>LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.</p>Formule :C13H10N2O2SCouleur et forme :SolidMasse moléculaire :258.3STAT5-IN-2
CAS :<p>STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).</p>Formule :C26H27N3ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :397.51(5Z,2E)-CU-3
CAS :<p>(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mM</p>Formule :C16H12N2O4S3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :392.47NVS-CECR2-1
CAS :<p>NVS-CECR2-1 is a CECR2 inhibitor with anti-tumor activity that inhibits chromatin binding of the CECR2 BRD.</p>Formule :C27H37N5O2SDegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :495.68USP7-IN-4
CAS :<p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>Formule :C29H34N6O3Degré de pureté :98.27% - 99.09%Couleur et forme :SolidMasse moléculaire :514.62Erasin
<p>Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.</p>Formule :C20H19N3O3Couleur et forme :SolidMasse moléculaire :349.38AZD 1152 (hydrochloride)
CAS :<p>AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.</p>Formule :C26H33Cl2FN7O6PCouleur et forme :SolidMasse moléculaire :660.47VU0424465
CAS :<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Formule :C19H19FN2O2Couleur et forme :SolidMasse moléculaire :326.36Nevanimibe
CAS :<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Formule :C27H39N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.62SCAL-266
CAS :<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Formule :C27H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.54Sparfosic Acid
CAS :<p>Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma</p>Formule :C6H10NO8PDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :255.12PARP1-IN-10
CAS :<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Formule :C20H23N3O5Couleur et forme :SolidMasse moléculaire :385.41ICG-001
CAS :<p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Formule :C33H32N4O4Degré de pureté :99.55% - 99.62%Couleur et forme :SolidMasse moléculaire :548.63CDK9-IN-18
CAS :<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Formule :C27H20N8OCouleur et forme :SolidMasse moléculaire :472.5PDPOB
CAS :<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formule :C15H20O5Couleur et forme :SolidMasse moléculaire :280.32Sparfosic acid trisodium
CAS :<p>Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumour</p>Formule :C6H9NNaO8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.1MSN-125
CAS :<p>MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.</p>Formule :C36H38BrN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :688.61ROC-325
CAS :<p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>Formule :C28H27ClN4OSDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :503.06Bcl-2-IN-9
CAS :<p>Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.</p>Formule :C27H31N7O3SCouleur et forme :SolidMasse moléculaire :533.65Gemcitabine monophosphate
CAS :<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Formule :C9H12F2N3O7PCouleur et forme :SolidMasse moléculaire :343.18PARP-2-IN-3
CAS :<p>PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.</p>Formule :C20H20ClN3O3Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :385.84RLX
CAS :<p>RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer,antitussive and anti-asthmatic activity,colon cancer，toxicity toward A549 cells..</p>Formule :C13H14N2ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :214.26GLS1 Inhibitor-4
CAS :<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formule :C29H27F3N10O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.72MMP-9-IN-5
CAS :<p>MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.</p>Formule :C27H20IN3O4Couleur et forme :SolidMasse moléculaire :577.37PK9327
CAS :<p>PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.</p>Formule :C21H22N2SCouleur et forme :SolidMasse moléculaire :334.48STAT3-IN-10
CAS :<p>STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).</p>Formule :C17H13NO5Couleur et forme :SolidMasse moléculaire :311.29PSB 0474
CAS :<p>P2Y6 receptor agonist</p>Formule :C17H20N2O13P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.29YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Formule :C25H26N6OCouleur et forme :SolidMasse moléculaire :426.51NF-κB-IN-5
CAS :<p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>Formule :C23H27N3O4Couleur et forme :SolidMasse moléculaire :409.48BIM-46174
CAS :<p>BIM-46174 has anticancer activity, inhibits the growth of a large number of human cancer cell lines, and induces caspase-3-dependent cancer cell apoptosis.</p>Formule :C22H30N4OSCouleur et forme :SolidMasse moléculaire :398.57(R)-STU104
CAS :<p>(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.</p>Formule :C18H18O4Degré de pureté :98.91% - 99.42%Couleur et forme :SolidMasse moléculaire :298.33IDH1 Inhibitor 9
CAS :<p>IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.</p>Formule :C26H30N4O3Couleur et forme :SolidMasse moléculaire :446.54Cyclamidomycin
CAS :<p>Cyclamidomycin is an antibiotic. It also functions as an inhibitor of nucleoside diphosphokinase of Escherichia coli.</p>Formule :C7H10N2OCouleur et forme :SolidMasse moléculaire :138.17L6H21
CAS :<p>L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.</p>Formule :C18H18O4Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :298.33SMBA1
CAS :<p>SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.</p>Formule :C20H13NO3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :315.32MM-102
CAS :<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Formule :C35H49F2N7O4Degré de pureté :98.77% - 99.99%Couleur et forme :SolidMasse moléculaire :669.8ARP 101
CAS :<p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>Formule :C20H26N2O5SDegré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :406.5BN201
CAS :<p>BN201 (OCS-05) is a neuroprotective drug by activating SGK2 and FOXO3 pathway. BN201 is able to regulate multiple kinases in the IGF1 pathway and cross BBB.</p>Formule :C25H38FN5O4Degré de pureté :99.42% - 99.42%Couleur et forme :SolidMasse moléculaire :491.6Tubulin polymerization-IN-22
CAS :<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Formule :C19H16O4Couleur et forme :SolidMasse moléculaire :308.33Anticancer agent 63
CAS :<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Formule :C17H24F3NOSeCouleur et forme :SolidMasse moléculaire :394.33Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Formule :C24H24N6OCouleur et forme :SolidMasse moléculaire :412.49(R)-eIF4A3-IN-2
CAS :<p>(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.</p>Formule :C25H19Br2ClN4O2Couleur et forme :SolidMasse moléculaire :602.71RGB-286147
CAS :<p>RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.</p>Formule :C23H22Cl2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.35Ferroptosis inducer-1
CAS :<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Formule :C25H21ClN2O5Couleur et forme :SolidMasse moléculaire :464.9SPRC
CAS :<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Formule :C6H9NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :159.21YC-137
CAS :<p>YC-137 inhibits BCL-2, triggers apoptosis in Bcl-2-high cells, and blocks its anti-apoptotic function.</p>Formule :C24H21N3O6S2Couleur et forme :SolidMasse moléculaire :511.57EGFR-IN-52
CAS :<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Formule :C19H18N4O3SCouleur et forme :SolidMasse moléculaire :382.44OXPHOS-IN-1
CAS :<p>OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).</p>Formule :C19H29N3O6S2Couleur et forme :SolidMasse moléculaire :459.58Targapremir-210
CAS :<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Formule :C32H36N10O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :592.69CCCI-01
CAS :<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Formule :C11H9N3O4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :247.21VEGFR-2-IN-23
CAS :<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Formule :C22H15N5O2Couleur et forme :SolidMasse moléculaire :381.39GKK1032B
CAS :<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Formule :C32H39NO4Couleur et forme :SolidMasse moléculaire :501.66Anticancer agent 50
CAS :<p>Anticancer agent 50 targets ABCB1 pump, has cytotoxic effects, alters cyclin D1/p53, and shows promise in T lymphoma research.</p>Formule :C30H32N2O4SeCouleur et forme :SolidMasse moléculaire :563.55Topoisomerase I inhibitor 3
CAS :<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Formule :C18H14FNO3Couleur et forme :SolidMasse moléculaire :311.31DAT-230
CAS :<p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>Formule :C20H21NO2SCouleur et forme :SolidMasse moléculaire :339.45AMPK activator 11
CAS :<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Formule :C25H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.45ZINC69391
CAS :<p>ZINC69391 inhibits Rac1, reduces cancer cell growth and metastasis, and induces apoptosis.</p>Formule :C14H14F3N5Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :309.29SAR125844
CAS :<p>SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)</p>Formule :C25H23FN8O2S2Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :550.63IST5-002
CAS :<p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.</p>Formule :C17H20N5O7PDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :437.34cRIPGBM
CAS :<p>cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.</p>Formule :C26H20FN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.45Rhosin
CAS :<p>Rhosin is a specific inhibitor of RhoA GTPases (Kd: ~0.4 uM), blocking RhoA-GEF interaction, not affecting Cdc42/Rac1/LARG, and induces apoptosis.</p>Formule :C20H18N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.4Selicrelumab
CAS :<p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>Degré de pureté :98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Couleur et forme :LiquidTJ08
CAS :<p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>Formule :C22H16FN3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :405.38Telomerase-IN-4
CAS :<p>Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].</p>Formule :C21H18N4OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.52Anticancer agent 147
CAS :<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Formule :C32H40BrN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.582'-Deoxyadenosine
CAS :<p>2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.</p>Formule :C10H13N5O3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :251.24(S)-PERK-IN-5
CAS :<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Formule :C25H26F2N4O3Couleur et forme :SolidMasse moléculaire :468.5Thioxodihydroquinazolinone-19
CAS :<p>Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.</p>Formule :C16H14N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.36A-802715
CAS :<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Formule :C16H26N4O3Degré de pureté :96.29%Couleur et forme :SolidMasse moléculaire :322.4Anticancer agent 99
CAS :<p>Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.</p>Formule :C19H20F3N3O2Couleur et forme :SolidMasse moléculaire :379.38MeOIstPyrd
CAS :<p>MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic</p>Formule :C14H16N4O2SCouleur et forme :SolidMasse moléculaire :304.37STAT3-IN-11
CAS :<p>STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.</p>Formule :C20H17NO4Degré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :335.35
