Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6223 produits trouvés pour "Apoptose"
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hnRNPK-IN-1
CAS :hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.Formule :C23H21N3O5Couleur et forme :SolidMasse moléculaire :419.43MRS 2693 trisodium salt
CAS :MRS 2693 trisodium salt is a P2Y6 agonist.Formule :C9H22IN5O12P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :581.15Luxeptinib
CAS :Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.Formule :C25H17F4N5O2Couleur et forme :SolidMasse moléculaire :495.43CB-64D
CAS :CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.Formule :C22H23NO2Couleur et forme :SolidMasse moléculaire :333.42Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Formule :C26H23NOCouleur et forme :SolidMasse moléculaire :365.47Anticancer agent 47
CAS :Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.Formule :C19H14N2O4SCouleur et forme :SolidMasse moléculaire :366.39p-DDAP
CAS :p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.Formule :C18H31NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.44HDAC6-IN-4
CAS :HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.Formule :C30H38N2O5Couleur et forme :SolidMasse moléculaire :506.63VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.Formule :C26H21ClF3N5O3S2Couleur et forme :SolidMasse moléculaire :608.05PK9327
CAS :PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.Formule :C21H22N2SCouleur et forme :SolidMasse moléculaire :334.48Sibiriline
CAS :Sibiriline is a Receptor-Interacting Protein Kinase 1 inhibitor that acts by preventing immune-dependent hepatitis.Formule :C13H10N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :210.23Ormeloxifene
CAS :estrogen receptor modulatorFormule :C30H35NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.6Fenoldopam hydrochloride
CAS :Fenoldopam HCl: D1 dopamine receptor agonist, vasodilator, doesn't cross blood-brain barrier, α2-adrenoceptor antagonist.Formule :C16H17Cl2NO3Couleur et forme :SolidMasse moléculaire :342.22Anticancer agent 63
CAS :Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.Formule :C17H24F3NOSeCouleur et forme :SolidMasse moléculaire :394.33CAY10406
CAS :CAY10406, a trifluoromethyl isatin sulfonamide, selectively targets and inhibits caspase-3 and -7, key in apoptosis, with no data on its inhibition potency.Formule :C27H23F3N2O5SCouleur et forme :SolidMasse moléculaire :544.54Hetrombopag
CAS :Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.Formule :C25H22N4O5Couleur et forme :SolidMasse moléculaire :458.47HJC-0123
CAS :HJC-0123: inhibits STAT3, boosts cleaved caspase-3, hinders cell growth, triggers apoptosis, effective in ER-negative breast/pancreatic cancer.Formule :C24H16N2O3SCouleur et forme :SolidMasse moléculaire :412.46PD-1/PD-L1-IN 6
CAS :Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.Formule :C25H26N2O3Couleur et forme :SolidMasse moléculaire :402.49Anticancer agent 31
CAS :Anticancer agent 31, a 1,3-diphenylurea quinoxaline derivative, halts S phase and triggers apoptosis.Formule :C28H21F2N5O2Couleur et forme :SolidMasse moléculaire :497.5ZYZ-488
CAS :ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Formule :C20H29N3O11Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :487.46XMD15-44
CAS :XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Formule :C29H29F3N4OCouleur et forme :SolidMasse moléculaire :506.56LS-104
CAS :LS-104 is a JAK2 inhibitor.Formule :C19H16N2O3Couleur et forme :SolidMasse moléculaire :320.34NSC745887
CAS :NSC745887 (compound 25) is an anticancer agent that demonstrates dose-dependent inhibition of proliferation across 60 cancer cell lines [1].Formule :C16H8N2O2Couleur et forme :SolidMasse moléculaire :260.25p-MPPF dihydrochloride
CAS :p-MPPF dihydrochloride is a 5-HT antagonist that can be used to study neurological diseases.Formule :C25H29Cl2FN4O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :507.43Caspase-3/7 activator 3
Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47IMM-H004
CAS :IMM-H004 is an effective inhibitor of BV2 microglia activation.Formule :C16H20N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.34AMXT1501
CAS :AMXT1501 is a polyamine uptake inhibitor, also inhibiting the putrescine transport in epimastigotes (the insect stage of t. cruzi)Formule :C32H68N6O2Couleur et forme :SolidMasse moléculaire :568.92Anticancer agent 32
CAS :Compound 2g, an anticancer agent, disrupts cell cycle and induces apoptosis for cancer research.Formule :C24H21F2N5OCouleur et forme :SolidMasse moléculaire :433.45MM-102
CAS :MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.Formule :C35H49F2N7O4Degré de pureté :98.77% - 99.99%Couleur et forme :SolidMasse moléculaire :669.8Ref: TM-T6333
1mg37,00€2mg49,00€5mg100,00€1mL*10mM (DMSO)147,00€10mg165,00€25mg334,00€50mg515,00€100mg737,00€GKK1032B
CAS :GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.Formule :C32H39NO4Couleur et forme :SolidMasse moléculaire :501.66CN128 hydrochloride
CAS :CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.
Formule :C15H18ClNO3Couleur et forme :SolidMasse moléculaire :295.76DNL343
CAS :DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.Formule :C20H19ClF3N3O4Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :457.835HPP-33
CAS :5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.Formule :C20H21NO3Couleur et forme :SolidMasse moléculaire :323.39A-385358
CAS :A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.Formule :C32H41N5O5S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :639.83Ref: TM-T14071
1mg57,00€5mg109,00€1mL*10mM (DMSO)158,00€10mg165,00€25mg268,00€50mg400,00€100mg567,00€ABD56
CAS :ABD56 inhibits osteoclast formation and activity in vitro and in vivo.Formule :C17H18O3Couleur et forme :SolidMasse moléculaire :270.32AD-2646
CAS :AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.Formule :C23H40N2O4Couleur et forme :SolidMasse moléculaire :408.57MEB55
CAS :MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.Formule :C22H17NO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :391.44VU 0364739 hydrochloride
CAS :VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.Formule :C26H28ClFN4O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :482.98Gea 3162
CAS :GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.Formule :C7H4Cl2N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.04Dabuzalgron HCl
CAS :Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence.Formule :C12H17Cl2N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.25MC-70
CAS :MC-70, P-gp and ABC transporter inhibitor (EC50=0.69 µM), interacts with ABCB1/G2/C1, inhibits colon cancer growth and induces apoptosis.Formule :C24H25NO3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :375.46CPI-7c
CAS :CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.Formule :C22H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.39SKLB70326
CAS :SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.Formule :C15H13N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.35Infliximab
CAS :Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.Degré de pureté :98% - 99.70%Couleur et forme :LiquidMasse moléculaire :145.98 kDaDPQZ
CAS :DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.Formule :C20H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.37PS121912
CAS :PS121912 is a potent and selective inhibitor of VDR-coactivator.Formule :C24H21F3N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.43hGGPPS-IN-2
CAS :hGGPPS-IN-2, a C2-ThP-BP analogue, inhibits hGGPPS, targets MM cells, induces apoptosis, and has anti-myeloma effects.Formule :C20H18FN5O7P2SCouleur et forme :SolidMasse moléculaire :553.4Necrostatin-7
CAS :Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.Formule :C16H10FN5OS2Degré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :371.41VS 8
CAS :VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.Formule :C26H20F3N3O3Couleur et forme :SolidMasse moléculaire :479.45Thienopyridone
CAS :Thienopyridone: potent, selective PRL phosphatase inhibitor, IC50s: 173/277/128 nM for PRL-1/2/3, induces apoptosis, anticancer.Formule :C13H10N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.3SB 706504
CAS :SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.Formule :C24H19F3N8ODegré de pureté :98.686%Couleur et forme :SolidMasse moléculaire :492.46IDH1 Inhibitor 9
CAS :IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.Formule :C26H30N4O3Couleur et forme :SolidMasse moléculaire :446.54Anti-inflammatory agent 54
CAS :Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expressionFormule :C17H16N2O5Couleur et forme :SolidMasse moléculaire :328.32PARP1-IN-31
CAS :PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).Formule :C22H15ClFN3O2Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :407.83SHP2-IN-8
CAS :SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.Formule :C17H21Cl2N5SCouleur et forme :SolidMasse moléculaire :398.35Bozepinib
CAS :Bozepinib is an antitumor compound that acts by inducing PKR-mediated apoptosis and synergizing with IFN.Formule :C20H14Cl2N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.332'-Deoxyadenosine
CAS :2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.Formule :C10H13N5O3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :251.24VEGFR-2-IN-28
CAS :VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.Formule :C26H17N7O7Couleur et forme :SolidMasse moléculaire :539.46Lexibulin dihydrochloride
CAS :Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.Formule :C24H32Cl2N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.46FL3
CAS :FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.Formule :C25H23BrO5Couleur et forme :SolidMasse moléculaire :483.35Benpyrine
CAS :Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.Formule :C16H16N6OCouleur et forme :SolidMasse moléculaire :308.34Flupenthixol
CAS :Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.Formule :C23H25F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.52Tubulin inhibitor 30
CAS :Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formule :C22H19N3O5Couleur et forme :SolidMasse moléculaire :405.4OXPHOS-IN-1
CAS :OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).Formule :C19H29N3O6S2Couleur et forme :SolidMasse moléculaire :459.58MBC-11
CAS :MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.Formule :C11H20N3O14P3Degré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :511.21DC-CPin711
CAS :DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.Formule :C23H22N4O2Couleur et forme :SolidMasse moléculaire :386.45HDAC-IN-39
CAS :HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.Formule :C27H26N4O4SCouleur et forme :SolidMasse moléculaire :502.58Semapimod
CAS :Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.Formule :C34H52N18O2Couleur et forme :SolidMasse moléculaire :744.9S116836
CAS :S116836 is a tyrosine kinase inhibitor.Formule :C27H21F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.49Didesmethylrocaglamide
CAS :Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,Formule :C27H27NO7Couleur et forme :SolidMasse moléculaire :477.51KRAS G12D inhibitor 14
CAS :KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM).Formule :C20H19F3N4OSDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :420.45BMS-1166 hydrochloride
CAS :"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."Formule :C36H34Cl2N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :677.57S130
CAS :S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.Formule :C24H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.47Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Formule :C29H30N6O2Couleur et forme :SolidMasse moléculaire :494.59R-8507
CAS :R-8507: TNF-αRI antagonist, blocks ICAM-1, halts receptor complex internalization, EC50: 2.45 μM (TNF-α), 3.79 μM (IL-1β).Formule :C16H8ClF3N4Couleur et forme :SolidMasse moléculaire :348.71PD1-PDL1-IN 1
CAS :PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.Formule :C14H23N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.38MMP-9-IN-5
CAS :MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.Formule :C27H20IN3O4Couleur et forme :SolidMasse moléculaire :577.37Mcl1-IN-4
CAS :Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formule :C28H26N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.58Topoisomerase II inhibitor 9
CAS :Topoisomerase II inhibitor 9: Topo II blocker (IC50: 0.97 μM), DNA intercalator (IC50: 43.51 μM), arrests G2/M in Hep G-2 cells and triggers apoptosis.
Formule :C22H17N7O3S2Couleur et forme :SolidMasse moléculaire :491.55HLI 373
CAS :HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.Formule :C18H23N5O2Couleur et forme :SolidMasse moléculaire :341.41ARP 101
CAS :ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.Formule :C20H26N2O5SDegré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :406.5Ref: TM-T22034
1mg94,00€5mg221,00€1mL*10mM (DMSO)241,00€10mg356,00€25mg737,00€50mg1.125,00€100mg1.521,00€200mg2.052,00€CRA-026440
CAS :CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7Formule :C23H24N4O4Degré de pureté :96.42%Couleur et forme :SolidMasse moléculaire :420.46IV-23
CAS :IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.Formule :C18H18BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.24Lemuteporfin
CAS :Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.Formule :C44H48N4O10Degré de pureté :97.14% - 99.44%Couleur et forme :SolidMasse moléculaire :792.87GRI977143
CAS :GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Formule :C22H17NO4SDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :391.44Gemcitabine monophosphate
CAS :R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.Formule :C9H12F2N3O7PCouleur et forme :SolidMasse moléculaire :343.18OT-82
CAS :OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Formule :C26H21FN4ODegré de pureté :98.91% - 99.315%Couleur et forme :SolidMasse moléculaire :424.47Ref: TM-T12330
2mg137,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.108,00€100mg1.468,00€CAY10747
CAS :CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.Formule :C42H48FNO6Couleur et forme :SolidMasse moléculaire :681.83MPT0B002
CAS :MPT0B002 is a microtubule inhibitor that acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cellsFormule :C19H19NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.36SCAL-266
CAS :SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.Formule :C27H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.54IZTZ-1
CAS :IZTZ-1: c-MYC G4 stabilizer, reduces expression, blocks cell cycle, induces apoptosis, inhibits B16 melanoma growth.Formule :C32H35N7SCouleur et forme :SolidMasse moléculaire :549.73PI3Kα-IN-7
CAS :PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.Formule :C17H22N8O2SCouleur et forme :SolidMasse moléculaire :402.47PDGFR-IN-1
CAS :PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formule :C25H30N8ODegré de pureté :99.13% - 99.49%Couleur et forme :SolidMasse moléculaire :458.56Ref: TM-T62872
1mg170,00€5mg432,00€1mL*10mM (DMSO)434,00€10mg655,00€25mg1.153,00€50mg1.665,00€100mg2.250,00€IM-54
CAS :IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.Formule :C19H23N3O2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :325.4NSC260594
CAS :NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-Formule :C29H24N6O3Couleur et forme :SolidMasse moléculaire :504.54B-Raf IN 9
CAS :B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).Formule :C23H20N4OSCouleur et forme :SolidMasse moléculaire :400.5NPD4928
CAS :NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Formule :C29H32N2O6Couleur et forme :SolidMasse moléculaire :504.57HS56
CAS :HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.Formule :C13H8ClN5OSCouleur et forme :SolidMasse moléculaire :317.75RET-IN-12
CAS :RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).Formule :C30H30F3N5O4Couleur et forme :SolidMasse moléculaire :581.59cRIPGBM
CAS :cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.Formule :C26H20FN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.45
