Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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SS28
CAS :<p>SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.</p>Formule :C18H20O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.35AP23464
CAS :<p>AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.</p>Formule :C26H30N5O2PCouleur et forme :SolidMasse moléculaire :475.52Antitumor agent-57
CAS :<p>Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.</p>Formule :C20H15NO5Couleur et forme :SolidMasse moléculaire :349.34CMC2.24
CAS :<p>CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.</p>Formule :C26H21NO5Couleur et forme :SolidMasse moléculaire :427.45PI3K-IN-33
CAS :<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Formule :C23H21BrN6O2Couleur et forme :SolidMasse moléculaire :493.36PI3Kδ-IN-11
CAS :<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Formule :C27H21N5OCouleur et forme :SolidMasse moléculaire :431.49(Rac)-Indoximod
CAS :<p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>Formule :C12H14N2O2Couleur et forme :SolidMasse moléculaire :218.25(S)-Erypoegin K
CAS :<p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.35Jolkinolide B
CAS :<p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>Formule :C20H26O4Degré de pureté :99.39% - 99.7%Couleur et forme :SolidMasse moléculaire :330.42CFM-5
CAS :<p>CFM-5 has anticonvulsant activity and is used in epilepsy research.</p>Formule :C23H18BrN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.38Mcl1-IN-11
CAS :<p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>Formule :C38H41N3O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :683.88Dinoprost
CAS :<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Formule :C20H34O5Degré de pureté :97.94% - 98.04%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :354.48MPT0B214
CAS :<p>MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.</p>Formule :C20H20N2O5Couleur et forme :SolidMasse moléculaire :368.38PD-1/PD-L1-IN-29
CAS :<p>PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.</p>Formule :C26H24N2O6Couleur et forme :SolidMasse moléculaire :460.48RIPK1-IN-13
CAS :<p>RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.</p>Formule :C21H20ClN3O3Couleur et forme :SolidMasse moléculaire :397.85HDAC-IN-36
CAS :<p>HDAC-IN-36: Oral HDAC6 inhibitor, IC50 = 11.68 nM, promotes apoptosis & autophagy, anti-tumor & anti-metastatic, for breast cancer research.</p>Formule :C29H39N5O5Couleur et forme :SolidMasse moléculaire :537.65p53 Activator 5
CAS :<p>Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Formule :C29H32F6N4OCouleur et forme :SolidMasse moléculaire :566.58ADU-S100
CAS :<p>ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.</p>Formule :C20H24N10O10P2S2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :690.54MMP2-IN-1
CAS :<p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>Formule :C15H13NO5SCouleur et forme :SolidMasse moléculaire :319.33Quinidine polygalacturonate
CAS :<p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>Formule :C26H34N2O9Couleur et forme :SolidMasse moléculaire :518.22643Cl-amidine
CAS :<p>Cl-amidine, an oral PAD inhibitor (IC50: 0.8-6.2 μM for PAD1/3/4), induces apoptosis in cancer cells.</p>Formule :C14H19ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.78CAY10747
CAS :<p>CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.</p>Formule :C42H48FNO6Couleur et forme :SolidMasse moléculaire :681.83Gemcitabine monophosphate
CAS :<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Formule :C9H12F2N3O7PCouleur et forme :SolidMasse moléculaire :343.18HLI98C
CAS :<p>HLI98C is a HDM2 ubiquitin ligase inhibitor with anti-tumor activity.</p>Formule :C17H9ClN4O4Couleur et forme :SolidMasse moléculaire :368.73BLM-IN-2
<p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>Formule :C33H38BrFN4OCouleur et forme :SolidMasse moléculaire :605.58SIRT6 activator 12q
CAS :<p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>Formule :C31H22N2O2Couleur et forme :SolidMasse moléculaire :454.52CEP-1612
CAS :<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Formule :C35H53N7O7Couleur et forme :SolidMasse moléculaire :683.84PSB 0474
CAS :<p>P2Y6 receptor agonist</p>Formule :C17H20N2O13P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.29Propiomazine
CAS :<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Formule :C20H24N2OSDegré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :340.48SKLB0565
CAS :<p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>Formule :C20H25ClN6OCouleur et forme :SolidMasse moléculaire :400.91Mcl1-IN-3
CAS :<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Formule :C27H22ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.93YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Formule :C25H26N6OCouleur et forme :SolidMasse moléculaire :426.51NSC114792
CAS :<p>NSC114792 is a selective JAK3 inhibitor.</p>Formule :C26H32N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.62CDK/HDAC-IN-2
CAS :<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Formule :C25H20Cl2N6O3Couleur et forme :SolidMasse moléculaire :523.37APPA
CAS :<p>APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of</p>Formule :C14H13NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.26Telomerase-IN-5
CAS :<p>Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].</p>Formule :C22H20N4OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.55AG311
CAS :<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Formule :C17H15N5SCouleur et forme :SolidMasse moléculaire :321.4YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Formule :C24H24N6OCouleur et forme :SolidMasse moléculaire :412.49(R)-STU104
CAS :<p>(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.</p>Formule :C18H18O4Degré de pureté :98.91% - 99.42%Couleur et forme :SolidMasse moléculaire :298.33L6H21
CAS :<p>L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.</p>Formule :C18H18O4Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :298.33RET-IN-15
CAS :<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Formule :C27H28N8O2Couleur et forme :SolidMasse moléculaire :496.56Anticancer agent 71
CAS :<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Formule :C18H13ClF3N5OCouleur et forme :SolidMasse moléculaire :407.78SB 706504
CAS :<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formule :C24H19F3N8ODegré de pureté :98.686%Couleur et forme :SolidMasse moléculaire :492.46Anticancer agent 67
CAS :<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Formule :C26H24F2N6O2S2Couleur et forme :SolidMasse moléculaire :554.63Quinidine Monosulfate
CAS :<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Formule :C40H50N4O8SCouleur et forme :SolidMasse moléculaire :746.92Topoisomerase II inhibitor 11
CAS :<p>Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).</p>Formule :C27H21BrCl2N2O2SCouleur et forme :SolidMasse moléculaire :588.34CCCI-01
CAS :<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Formule :C11H9N3O4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :247.21Anticancer agent 76
CAS :<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Formule :C32H33NO5SCouleur et forme :SolidMasse moléculaire :543.67Nec-3a
CAS :<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Formule :C21H18F4N2O4Couleur et forme :SolidMasse moléculaire :438.37PD-1-IN-18
CAS :<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Formule :C11H17N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.28CU-3
CAS :<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Formule :C16H12N2O4S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.47HBV-IN-23
CAS :<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Formule :C25H27N3O3SCouleur et forme :SolidMasse moléculaire :449.57TRAF-STOP inhibitor 6877002
CAS :<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formule :C17H17NODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :251.32Justicidin B
CAS :<p>Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.</p>Formule :C21H16O6Couleur et forme :SolidMasse moléculaire :364.35BP-1-108
CAS :<p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>Formule :C32H38N2O6SCouleur et forme :SolidMasse moléculaire :578.72SMBA2
CAS :<p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>Formule :C8H16N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :168.24RC-33 HCl
CAS :<p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>Formule :C21H28ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.91BMS-242
CAS :<p>BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.</p>Formule :C28H35NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :449.58α-NETA
CAS :<p>α-NETA is a ChA inhibitor and an ALDH1A1 and CMKLR1 antagonist with anticancer activity and inhibits cholinesterase and acetylcholinesterase (AChE).</p>Formule :C16H20INODegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :369.24TL02-59 dihydrochloride
CAS :<p>TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).</p>Formule :C32H36Cl2F3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :682.56AZM475271
CAS :<p>AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)</p>Formule :C23H27ClN4O3Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :442.94Lemuteporfin
CAS :<p>Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.</p>Formule :C44H48N4O10Degré de pureté :97.14% - 99.44%Couleur et forme :SolidMasse moléculaire :792.87Mps1-IN-5
CAS :<p>Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.</p>Formule :C24H25N9Couleur et forme :SolidMasse moléculaire :439.52GK563
CAS :<p>GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.</p>Formule :C16H22O2Couleur et forme :SolidMasse moléculaire :246.34(S)-Elobixibat
CAS :<p>(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.</p>Formule :C36H45N3O7S2Couleur et forme :SolidMasse moléculaire :695.89CN128 hydrochloride
CAS :<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Formule :C15H18ClNO3Couleur et forme :SolidMasse moléculaire :295.76PIK-C98
CAS :<p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>Formule :C16H10Cl2N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.23MRS 2693 trisodium salt
CAS :<p>MRS 2693 trisodium salt is a P2Y6 agonist.</p>Formule :C9H22IN5O12P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :581.15A-802715
CAS :<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Formule :C16H26N4O3Degré de pureté :96.29%Couleur et forme :SolidMasse moléculaire :322.4B-Raf IN 9
CAS :<p>B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).</p>Formule :C23H20N4OSCouleur et forme :SolidMasse moléculaire :400.5Tubulin polymerization-IN-14
CAS :<p>Tubulin-IN-14 (20a) inhibits polymerization (IC50=3.15μM), has anti-cancer and anti-vascular effects, inducing cell death.</p>Formule :C15H15ClN2O2Couleur et forme :SolidMasse moléculaire :290.74YM-155 hydrochloride
CAS :<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Formule :C20H19ClN4O3Couleur et forme :SolidMasse moléculaire :398.85PI3Kα-IN-7
CAS :<p>PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.</p>Formule :C17H22N8O2SCouleur et forme :SolidMasse moléculaire :402.47Luxeptinib
CAS :<p>Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.</p>Formule :C25H17F4N5O2Couleur et forme :SolidMasse moléculaire :495.43(rel)-Oxaliplatin
CAS :<p>(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.</p>Formule :C8H14N2O4PtCouleur et forme :SolidMasse moléculaire :397.29Selicrelumab
CAS :<p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>Degré de pureté :98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Couleur et forme :LiquidVin-F03
CAS :<p>Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.</p>Formule :C22H29N3Couleur et forme :SolidMasse moléculaire :335.49VEGFR-2-IN-22
CAS :<p>VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.</p>Formule :C26H24ClFN4O6Couleur et forme :SolidMasse moléculaire :542.94c-Fms-IN-12
CAS :<p>c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.</p>Formule :C30H32N6O6Couleur et forme :SolidMasse moléculaire :572.61iMAC2
CAS :<p>iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibiting</p>Formule :C19H20Br2FN3Couleur et forme :SolidMasse moléculaire :469.19VU 0364739 hydrochloride
CAS :<p>VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.</p>Formule :C26H28ClFN4O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :482.98FAK-IN-5
CAS :<p>FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.</p>Formule :C29H29ClF3N3O4Couleur et forme :SolidMasse moléculaire :576.01MMP-9-IN-3
CAS :<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Formule :C29H25N3O4Couleur et forme :SolidMasse moléculaire :479.53ZMF-10
CAS :<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Formule :C19H17F6N7OCouleur et forme :SolidMasse moléculaire :473.38αβ-Tubulin-IN-1
CAS :<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Formule :C25H19N3O3Couleur et forme :SolidMasse moléculaire :409.44PCAF-IN-2
CAS :<p>PCAF-IN-2 inhibits PCAF (IC50 = 5.31 µM), induces apoptosis, and halts G2/M cell cycle, showing anti-tumor properties.</p>Formule :C10H7F3N6Couleur et forme :SolidMasse moléculaire :268.2STAT3-IN-3
CAS :<p>STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.</p>Formule :C27H26BrN3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :600.48CDK6/PIM1-IN-1
CAS :<p>CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.</p>Formule :C25H28FN9Couleur et forme :SolidMasse moléculaire :473.55Nevanimibe
CAS :<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Formule :C27H39N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.62PARP1-IN-10
CAS :<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Formule :C20H23N3O5Couleur et forme :SolidMasse moléculaire :385.41Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Formule :C26H23NOCouleur et forme :SolidMasse moléculaire :365.47CMLD012612
CAS :<p>CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).</p>Formule :C31H33N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :559.61Anticancer agent 47
CAS :<p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>Formule :C19H14N2O4SCouleur et forme :SolidMasse moléculaire :366.39Ceranib-2
CAS :<p>Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.</p>Formule :C25H19NO3Degré de pureté :98.49%Couleur et forme :SolidMasse moléculaire :381.42Darinaparsin
CAS :<p>Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.</p>Formule :C12H22AsN3O6SCouleur et forme :SolidMasse moléculaire :411.31EGFR-IN-51
CAS :<p>EGFR-IN-51 effectively inhibits EGFR and mutations with IC50s of 0.493-461.63 μM; it induces apoptosis in cancer cells.</p>Formule :C21H15N3O2SCouleur et forme :SolidMasse moléculaire :373.43Brigimadlin
CAS :<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Formule :C31H25Cl2FN4O3Degré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :591.46Cot inhibitor-1
CAS :<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Formule :C27H27Cl2FN8Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :553.46NM-3
CAS :<p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>Formule :C13H12O6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :264.23Tubulin inhibitor 32
CAS :<p>Tubulin inhibitor 32 is a microtubule inhibitor with antiproliferative and antitumor activity that induces apoptosis and cell cycle arrest in the G2/M phase.</p>Formule :C18H19N3O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :325.36
