Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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Antitumor agent-81
CAS :Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.Formule :C19H19N7O3Couleur et forme :SolidMasse moléculaire :393.4E64FC26
CAS :E64FC26 is a PDI family pan-inhibitor with antitumor activity that inhibits PDIA1 and PDIA6 and can be used to study multiple myeloma and pancreatic cancer.Formule :C19H23F3O2Degré de pureté :98.1% - 98.1%Couleur et forme :SolidMasse moléculaire :340.38Pim-1 kinase inhibitor 1
CAS :Pim-1 kinase inhibitor 1, IC50 0.11 μM, combats various cancers by inducing apoptosis.Formule :C19H13N3O3Couleur et forme :SolidMasse moléculaire :331.32BTK-IN-24
CAS :BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.Formule :C26H19F4N5O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :509.46Zonisamide sodium
CAS :Zonisamide sodium is a 1,2 benzisoxazole derivative. It is the first agent of this chemical class to be developed as an antiepileptic drug.Formule :C8H8N2NaO3SDegré de pureté :98%Couleur et forme :Off-White SolidMasse moléculaire :235.22Perillic acid
CAS :Perillic acid, a perillyl alcohol metabolite, induces lung cancer cell arrest, apoptosis, and has anti-HSV-1 and immune-modulating effects.Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22Antitumor agent-53
CAS :Antitumor agent-53 hinders tumor growth, induces G2/M cell cycle arrest, and triggers apoptosis via PI3K/AKT in HGC-27 cells.Formule :C24H18FN3OCouleur et forme :SolidMasse moléculaire :383.42PTG-0861
CAS :PTG-0861 is a selective HDAC6 inhibitor with an IC50 of 5.92 nm, promising for hematological cancer research.Formule :C15H9F5N2O3Couleur et forme :SolidMasse moléculaire :360.24Anticancer agent 32
CAS :Compound 2g, an anticancer agent, disrupts cell cycle and induces apoptosis for cancer research.Formule :C24H21F2N5OCouleur et forme :SolidMasse moléculaire :433.45AKCI
CAS :AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.Formule :C19H27N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.46Anticancer agent 31
CAS :Anticancer agent 31, a 1,3-diphenylurea quinoxaline derivative, halts S phase and triggers apoptosis.Formule :C28H21F2N5O2Couleur et forme :SolidMasse moléculaire :497.5hGGPPS-IN-2
CAS :hGGPPS-IN-2, a C2-ThP-BP analogue, inhibits hGGPPS, targets MM cells, induces apoptosis, and has anti-myeloma effects.Formule :C20H18FN5O7P2SCouleur et forme :SolidMasse moléculaire :553.4RETRA
CAS :RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.Formule :C11H12BrNO3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.25NMK-TD-100
CAS :NMK-TD-100: Microtubule disruptor, anti-proliferative, blocks mitosis, causes apoptosis in HeLa; IC50=17.5µM for tubulin polymerization.Formule :C19H17N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.42(4R,9S)-AG 205
CAS :AG-205 is a potent inhibitor of FabK, the enoyl-ACP reductase in Streptococcus pneumoniae.Formule :C22H23ClN6OSCouleur et forme :SolidMasse moléculaire :454.98SB 706504
CAS :SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.Formule :C24H19F3N8ODegré de pureté :98.686%Couleur et forme :SolidMasse moléculaire :492.46Norartocarpetin
CAS :Norartocarpetin inhibits tyrosinase (IC50 0.47μM), prevents browning in food, and fights lung cancer (IC50 22μM) by disrupting cell mechanisms.Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.24Cl-Necrostatin-1
CAS :Cl-Necrostatin-1 is an inhibitor of receptor-interacting protein kinase. It inhibits RIPK1 activity.Formule :C13H12ClN3OSCouleur et forme :SolidMasse moléculaire :293.77SHP2-IN-8
CAS :SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.Formule :C17H21Cl2N5SCouleur et forme :SolidMasse moléculaire :398.35FL3
CAS :FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.Formule :C25H23BrO5Couleur et forme :SolidMasse moléculaire :483.35Flupenthixol
CAS :Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.Formule :C23H25F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.52HDAC-IN-39
CAS :HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.Formule :C27H26N4O4SCouleur et forme :SolidMasse moléculaire :502.58RSH-7
CAS :RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducingFormule :C22H25FN8ODegré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :436.493-ATA
CAS :3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.Formule :C13H10N2SCouleur et forme :SolidMasse moléculaire :226.3BMS-1166 hydrochloride
CAS :"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."Formule :C36H34Cl2N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :677.57CAY10406
CAS :CAY10406, a trifluoromethyl isatin sulfonamide, selectively targets and inhibits caspase-3 and -7, key in apoptosis, with no data on its inhibition potency.Formule :C27H23F3N2O5SCouleur et forme :SolidMasse moléculaire :544.54AK301
CAS :AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).Formule :C19H21ClN2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :344.843,5-dimethyl PIT-1
CAS :PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such asFormule :C16H15N3O4SCouleur et forme :SolidMasse moléculaire :345.37BMS-200
CAS :BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.Formule :C27H27F2NO6Couleur et forme :SolidMasse moléculaire :499.5IV-23
CAS :IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.Formule :C18H18BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.2415(S)-HpETE
CAS :15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47OT-82
CAS :OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Formule :C26H21FN4ODegré de pureté :98.91% - 99.315%Couleur et forme :SolidMasse moléculaire :424.47Ref: TM-T12330
2mg137,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.108,00€100mg1.468,00€Nimustine
CAS :Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.Formule :C9H13ClN6O2Couleur et forme :SolidMasse moléculaire :272.69BN201
CAS :BN201 (OCS-05) is a neuroprotective drug by activating SGK2 and FOXO3 pathway. BN201 is able to regulate multiple kinases in the IGF1 pathway and cross BBB.Formule :C25H38FN5O4Degré de pureté :99.42% - 99.42%Couleur et forme :SolidMasse moléculaire :491.6S1QEL1.1
CAS :S1QEL1.1 (S1QEL) is an electron leakage inhibitor that inhibits O2-induced ROS generation and prevents O2-induced DA closure.Formule :C23H24N4O3SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :436.53Antitumor agent-70
CAS :Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.Formule :C21H18N4O2Couleur et forme :SolidMasse moléculaire :358.39HS56
CAS :HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.Formule :C13H8ClN5OSCouleur et forme :SolidMasse moléculaire :317.75Merck-22-6
CAS :Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.Formule :C40H43N7O2Couleur et forme :SolidMasse moléculaire :653.82SMI-6860766
CAS :SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.Formule :C15H11BrClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.61HJC-0123
CAS :HJC-0123: inhibits STAT3, boosts cleaved caspase-3, hinders cell growth, triggers apoptosis, effective in ER-negative breast/pancreatic cancer.Formule :C24H16N2O3SCouleur et forme :SolidMasse moléculaire :412.46RLX
CAS :RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer,antitussive and anti-asthmatic activity,colon cancer，toxicity toward A549 cells..Formule :C13H14N2ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :214.26BPTQ
CAS :BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.Formule :C17H16N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.4VU 0364739 hydrochloride
CAS :VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.Formule :C26H28ClFN4O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :482.98Setafrastat
CAS :Setafrastat is a vascular endothelial growth factor (VEGF) promotor and rotamase inhibitor.Formule :C25H33F2N3O4Couleur et forme :SolidMasse moléculaire :477.54PARP-2-IN-3
CAS :PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.
Formule :C20H20ClN3O3Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :385.84Anticancer agent 57
CAS :Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.Formule :C20H21Cl2NO2Couleur et forme :SolidMasse moléculaire :378.29Filanesib
CAS :Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.Formule :C20H22F2N4O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :420.48VEGFR-2-IN-19
CAS :VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.Formule :C21H19N3O2Couleur et forme :SolidMasse moléculaire :345.39Imofinostat
CAS :Imofinostat (MPT0E028) is a selective, orally available pan-HDAC inhibitor with IC₅₀ values of 53.0/106.2/29.5 nM against HDAC1/HDAC2/HDAC6 in HCT116 cells.Formule :C17H16N2O4SDegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :344.38Ref: TM-T16131
1mg92,00€5mg192,00€1mL*10mM (DMSO)212,00€10mg281,00€25mg595,00€50mg895,00€100mg1.558,00€MG-115
CAS :MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.Formule :C25H39N3O5Degré de pureté :97.10%Couleur et forme :White PowderMasse moléculaire :461.59RET-IN-6
CAS :RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).Formule :C30H29N7Couleur et forme :SolidMasse moléculaire :487.6SKF1
CAS :SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.Formule :C23H37ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.01BCL6-IN-8c
CAS :BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbentFormule :C20H20ClN3O5Couleur et forme :SolidMasse moléculaire :417.84eIF4A3-IN-2
CAS :eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Formule :C25H19Br2ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.71Ivaltinostat
CAS :CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.Formule :C24H33N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.54XMD15-44
CAS :XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Formule :C29H29F3N4OCouleur et forme :SolidMasse moléculaire :506.56Tubulin polymerization-IN-24
CAS :HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.Formule :C22H16O3Couleur et forme :SolidMasse moléculaire :328.36Ferroptosis-IN-4
CAS :Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Formule :C17H24ClN3O2Masse moléculaire :337.84TP-472
CAS :TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).Formule :C20H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.38GW7845
CAS :GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.Formule :C29H28N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.54Metoprolol fumarate
CAS :Metoprolol fumarate (CGP 2175C): selective β1-blocker with anti-inflammatory, antitumor, anti-angiogenic effects.Formule :C34H54N2O10Couleur et forme :SolidMasse moléculaire :650.8Shield-2
CAS :Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.Formule :C35H51N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.8Anticancer agent 77
CAS :Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.Formule :C25H30BrN7Couleur et forme :SolidMasse moléculaire :508.46MMPSI
CAS :MMPSI (Caspase-3/7 Inhibitor I) is a caspase 3 and caspase 7 inhibitor that inhibits ischemic injury in cardiomyocytes and can be used to study cardioprotectionFormule :C14H16N2O5SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :324.35NSC745887
CAS :NSC745887 (compound 25) is an anticancer agent that demonstrates dose-dependent inhibition of proliferation across 60 cancer cell lines [1].Formule :C16H8N2O2Couleur et forme :SolidMasse moléculaire :260.25D-Cl-amidine
CAS :D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.Formule :C14H19ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.78PBOX-15
CAS :PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.Formule :C28H19NO3Couleur et forme :SolidMasse moléculaire :417.46Paclitaxel Ceribate
CAS :Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.Formule :C51H57NO18Couleur et forme :SolidMasse moléculaire :971.99C1A
CAS :C1A is an inhibitor of HDAC6 which modulates downstream autophagy substrates and leads to growth inhibition of a diverse set of cancer cell lines.Formule :C22H25Cl2N3O4SCouleur et forme :SolidMasse moléculaire :498.42Ceranib-2
CAS :Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.Formule :C25H19NO3Degré de pureté :98.49%Couleur et forme :SolidMasse moléculaire :381.42F5446
CAS :F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Formule :C26H17ClN2O8SDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :552.94HDAC8-IN-3
CAS :HDAC8-IN-3 (P19) inhibits HDAC8 (IC50 9.3 μM), induces leukemic cell apoptosis, and enhances thermal stability.Formule :C18H12N4O3S2Couleur et forme :SolidMasse moléculaire :396.44KS106
CAS :KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.Formule :C18H15BrF3N3O2SDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :474.3CAM 833
CAS :CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.Formule :C26H26ClFN4O5Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :528.96AG-024322
CAS :AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.Formule :C23H20F2N6Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :418.44ZDLD13
CAS :ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.Formule :C18H14N4OCouleur et forme :SolidMasse moléculaire :302.33CTX1
CAS :CTX1 is a small molecule activator of p53.Formule :C14H10N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.26DRAK2-IN-1
CAS :Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.41LSD1-IN-14
CAS :LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.Formule :C21H24FN5Couleur et forme :SolidMasse moléculaire :365.45BJE6-106
CAS :BJE6-106, Selective PKCδ inhibitor (IC50=0.05 μM), induces caspase-dependent apoptosis, activates JNK/H2AX, for NRAS-mutated melanoma.Formule :C26H23NO2Couleur et forme :SolidMasse moléculaire :381.47DNL343
CAS :DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.Formule :C20H19ClF3N3O4Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :457.83GDP366
CAS :GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.Formule :C20H17N5OSDegré de pureté :98.78% - 99.84%Couleur et forme :SolidMasse moléculaire :375.45Mcl1-IN-9
CAS :Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.Formule :C37H39ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :639.18CSRM617
CAS :CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.Formule :C10H13N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :255.23Nafamostat hydrochloride
CAS :Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.Formule :C19H19Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.29KU-0058948
CAS :KU-0058948: PARP inhibitor, triggers cell cycle arrest and apoptosis in myeloid leukemia cells in vitro.Formule :C21H21FN4O2Couleur et forme :SolidMasse moléculaire :380.42TSI-13-57
CAS :TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization ,inhibits LPS-induced TNF-α (IC50 = 6.73 mM).Formule :C28H29N3O3Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :455.55Infliximab
CAS :Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.Degré de pureté :98% - 99.70%Couleur et forme :LiquidMasse moléculaire :145.98 kDaNecrostatin-7
CAS :Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.Formule :C16H10FN5OS2Degré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :371.41Arecaidine propargyl ester (hydrobromide)
CAS :Arecaidine propargyl ester: selective M2 muscarinic receptor agonist, induces guinea pig atrium contraction, lowers cat blood pressure, toxic to flies.Formule :C10H14BrNO2Couleur et forme :SolidMasse moléculaire :260.13HSP90-IN-13
CAS :HSP90-IN-13 (5k): potent HSP90 inhibitor, IC50 25.07 nM, targets EGFR/VEGFR-2/Topo-2, blocks MCF-7 G2/M cycle, induces apoptosis.Formule :C26H21N5O3SCouleur et forme :SolidMasse moléculaire :483.54Allethrin
CAS :Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.Formule :C19H26O3Degré de pureté :99.52%Masse moléculaire :302.41hCAIX-IN-12
CAS :hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.Formule :C18H14N4O3S2Couleur et forme :SolidMasse moléculaire :398.46Antitumor agent-45
CAS :Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis.Formule :C28H17BrFN5O3Couleur et forme :SolidMasse moléculaire :570.37UA 62784
CAS :Blocks microtubule growth, spurs cell apoptosis, enhances vinblastine's effect in HeLa cells, mistakenly seen as CENP-E ATPase inhibitor.Formule :C23H15NO3Couleur et forme :SolidMasse moléculaire :353.37NSC745885
CAS :NSC745885, Antitumor agent, downregulates EZH2 via proteasomal degradation, toxic to drug-resistant cancer lines, for bladder and oral cancer.Formule :C14H6N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :266.27bpV(phen)
CAS :bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).Formule :C12H8KN2O5VDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.24RIPK3-IN-2
CAS :RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.Formule :C21H16ClN3O2S2Couleur et forme :SolidMasse moléculaire :441.95MIR002
CAS :MIR002: an oral POLA1/HDAC11 inhibitor with antitumor effects, enhances p53/p21, causes G1/S arrest, and triggers apoptosis.Formule :C27H29NO5Couleur et forme :SolidMasse moléculaire :447.52MI-192
CAS :MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.Formule :C24H21N3O2Couleur et forme :SolidMasse moléculaire :383.44
