Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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Cipepofol
CAS :<p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>Formule :C14H20ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :204.31A09-003
CAS :<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Formule :C23H26N4ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :374.48Imipramine
CAS :<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Formule :C19H24N2Degré de pureté :99.4%Couleur et forme :White To Off-White /Hydrochloride/ SolidMasse moléculaire :280.41Brigimadlin
CAS :<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Formule :C31H25Cl2FN4O3Degré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :591.46BCL6-IN-7
CAS :<p>BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.</p>Formule :C18H15ClN6ODegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :366.8Mepazine
CAS :<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Formule :C19H22N2SDegré de pureté :99.88% - 99.92%Couleur et forme :SolidMasse moléculaire :310.46LCS3
CAS :<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Formule :C11H7ClN2O4Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :266.64NSC49652
CAS :<p>NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.</p>Formule :C14H11NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :225.24TT01001
CAS :<p>TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.</p>Formule :C15H19Cl2N3O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :376.3XX-650-23
CAS :<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Formule :C18H12N2O2Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :288.3MBM-55
CAS :<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Formule :C28H27FN6O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :498.55Tubulin inhibitor 32
CAS :<p>Tubulin inhibitor 32 is a microtubule inhibitor with antiproliferative and antitumor activity that induces apoptosis and cell cycle arrest in the G2/M phase.</p>Formule :C18H19N3O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :325.36RIPK3-IN-1
CAS :<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Formule :C29H25FN4O4Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :512.53HS-276
CAS :<p>HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.</p>Formule :C24H29N5O2Degré de pureté :97.852% - 98.81%Couleur et forme :SolidMasse moléculaire :419.52TAI-1
CAS :<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Formule :C24H21N3O3SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :431.51Trk-IN-9
CAS :<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Formule :C23H24ClFN6ODegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :454.93Atrosab
CAS :<p>Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases.</p>Degré de pureté :SDS-PAGE:>95%;SEC-HPLC:95.22%Couleur et forme :LiquidMasse moléculaire :146.12 kDaRS1-PDK1 inhibitor
CAS :<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Formule :C15H9ClN2O2S3Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :380.89EM-12
CAS :<p>EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.</p>Formule :C13H12N2O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :244.25SLMP53-1
CAS :<p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>Formule :C20H18N2O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :318.37LQZ-7F
CAS :<p>LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.</p>Formule :C14H7N9O3Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :349.26Erastin2
CAS :<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formule :C36H35ClN4O4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :623.14UC-112
CAS :<p>UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).</p>Formule :C22H24N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :348.44HS38
CAS :<p>HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.</p>Formule :C14H12ClN5O2SDegré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :349.8CSN5i-3
CAS :<p>CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5, as an anticancer agent.Cost-effective and quality-assured.</p>Formule :C28H29F2N5O2Degré de pureté :99.56% - >99.99%Couleur et forme :SolidMasse moléculaire :505.56KR-33493
CAS :<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Formule :C20H18BrN3O3SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :460.34Bomedemstat ditosylate
CAS :<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Formule :C42H50FN7O8S2Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :864.02Gallium maltolate
CAS :<p>Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.</p>Formule :C18H15GaO9Degré de pureté :99.61% - 99.67%Couleur et forme :SolidMasse moléculaire :445.03Anticancer agent 110
CAS :<p>Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells</p>Formule :C18H13FN6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.4MMRi64
CAS :<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Formule :C22H17Cl2N3ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :410.3SYM 2081
CAS :<p>SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.</p>Formule :C6H11NO4Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :161.16Ro 08-2750
CAS :<p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>Formule :C13H10N4O3Degré de pureté :98.795%Couleur et forme :SolidMasse moléculaire :270.24AMG PERK 44
CAS :<p>AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.</p>Formule :C34H29ClN4O2Degré de pureté :98.8% - 99.81%Couleur et forme :SolidMasse moléculaire :561.07GSK2593074A
CAS :<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Formule :C27H23N5OSDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :465.57Sarmustine
CAS :<p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>Formule :C6H11ClN4O3Degré de pureté :98.29% - 99.71%Couleur et forme :SolidMasse moléculaire :222.63Pyrazoloacridine
CAS :<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Formule :C19H21N5O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :367.4Apostatin-1
CAS :<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Formule :C19H27N3OSDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :345.5Antifolate C2
CAS :<p>Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.</p>Formule :C19H21N5O6SDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.46GSK854
CAS :<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Formule :C18H19ClN6O4S2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :482.96Epristeride
CAS :<p>Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.</p>Formule :C25H37NO3Degré de pureté :98.12% - >99.99%Couleur et forme :SolidMasse moléculaire :399.57HTH-01-091
CAS :<p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>Formule :C26H28Cl2N4O2Degré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :499.43GS-9191
CAS :<p>GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which</p>Formule :C37H51N8O6PDegré de pureté :98.01 - 99.28%Couleur et forme :SolidMasse moléculaire :734.82CTA 056
CAS :<p>CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.</p>Formule :C35H34N6ODegré de pureté :97.22% - 97.76%Couleur et forme :SolidMasse moléculaire :554.68VAS 3947
CAS :<p>VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.</p>Formule :C14H10N6OSDegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :310.33Ciglitazone
CAS :<p>Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.</p>Formule :C18H23NO3SDegré de pureté :98.23% - 99.59%Couleur et forme :White Cyrstalline SolidMasse moléculaire :333.45GSK-3β inhibitor 3
CAS :<p>GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3</p>Formule :C18H14FNO2SDegré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :327.37CUDC-427
CAS :<p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>Formule :C29H36N6O4SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :564.7AZA1
CAS :<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Formule :C22H20N6Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :368.43EGFR-IN-11
CAS :<p>EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.</p>Formule :C29H35N9O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :573.71DB1976
CAS :<p>DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.</p>Formule :C20H16N8SeDegré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :447.35CCT018159
CAS :<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Formule :C20H20N2O4Degré de pureté :98.78% - 99.79%Couleur et forme :SolidMasse moléculaire :352.38P505-15 Acetate
CAS :<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Formule :C21H27N9O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :453.5Tiomolibdate diammonium
CAS :<p>Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.</p>Formule :H8MoN2S4Degré de pureté :98%Couleur et forme :Brown To Black Iridescent Crystalline PowderMasse moléculaire :260.281G244
CAS :<p>1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.</p>Formule :C29H30F2N4O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :504.57ZDLD20
CAS :<p>ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.</p>Formule :C22H22N6ODegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :386.45HBED
CAS :<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formule :C20H24N2O6Degré de pureté :97.35% - 98.58%Couleur et forme :SolidMasse moléculaire :388.41GCN2-IN-1
CAS :<p>GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.</p>Formule :C19H18N10ODegré de pureté :99.49% - 99.64%Couleur et forme :SolidMasse moléculaire :402.41LDCA
CAS :<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Formule :C8H5Cl3FNODegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :256.49STAT3-IN-13
CAS :<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formule :C21H20N6O3SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :436.49Etomoxir
CAS :<p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>Formule :C17H23ClO4Degré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :326.82DCG066
CAS :<p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>Formule :C30H31F6N3O2Degré de pureté :98.26% - 98.38%Couleur et forme :SolidMasse moléculaire :579.58Prinomastat
CAS :<p>Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.</p>Formule :C18H21N3O5S2Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :423.51Sabizabulin
CAS :<p>Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.</p>Formule :C21H19N3O4Degré de pureté :98.10% - 99.79%Couleur et forme :SolidMasse moléculaire :377.39BCP-T.A
CAS :<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formule :C23H19Cl2N3OSDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :456.39DK419
CAS :<p>DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.</p>Formule :C16H8ClF6N3ODegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :407.7p53-MDM2-IN-1
CAS :<p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>Formule :C23H20ClN3O3Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :421.88Dasatinib hydrochloride
CAS :<p>Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).</p>Formule :C22H27Cl2N7O2SDegré de pureté :99.88% - 99.98%Couleur et forme :SolidMasse moléculaire :524.47UCB-5307
CAS :<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formule :C22H21N3ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :343.42RO-5963
CAS :<p>RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).</p>Formule :C24H21ClF2N4O5Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :518.9Vamotinib
CAS :<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Formule :C29H27F3N6ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :532.56UK-101
CAS :<p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>Formule :C25H48N2O5SiDegré de pureté :99.08% - 99.25%Couleur et forme :SolidMasse moléculaire :484.74R306465
CAS :<p>R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.</p>Formule :C19H19N5O4SDegré de pureté :98.46% - 99.54%Couleur et forme :SolidMasse moléculaire :413.45NecroX-7
CAS :<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Formule :C24H29N3O3SDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :439.57UNC0321
CAS :<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Formule :C27H45N7O3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :515.69SPD304 dihydrochloride
CAS :<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Formule :C32H34Cl2F3N3O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :620.53F16
CAS :<p>F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.</p>Formule :C16H15IN2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :362.21PARP/PI3K-IN-1
CAS :<p>PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.</p>Formule :C33H28F4N8O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :660.62Necrostatin-5
CAS :<p>Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.</p>Formule :C19H17N3O2S2Degré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :383.49SCFSkp2-IN-2
CAS :<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Formule :C17H20N4O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :312.37RET-IN-23
CAS :<p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>Formule :C28H28FN11Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :537.59K-8012
CAS :<p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>Formule :C23H23FN4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :374.45Stemazole
CAS :<p>Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.</p>Formule :C9H9N5OS2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :267.33BC 11 hydrobromide
CAS :<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Formule :C8H12BBrN2O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :290.97C6 Ceramide
CAS :<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Formule :C24H47NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :397.63TL4-12
CAS :<p>TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.</p>Formule :C25H27F3N6O2Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :500.52MJN68390
CAS :<p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>Formule :C24H28ClN3O3Degré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :441.95Exisulind
CAS :<p>Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.</p>Formule :C20H17FO4SDegré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :372.41SB 699551 dihydrochloride
CAS :<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Formule :C34H47Cl2N3ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :584.66Tubulin inhibitor 11
CAS :<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Formule :C22H23N3O3SDegré de pureté :98.32%Couleur et forme :SoildMasse moléculaire :409.5CDK9-IN-7
CAS :<p>CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.</p>Formule :C29H37N7O2SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :547.71cRIPGBM chloride
CAS :<p>cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.</p>Formule :C26H20ClFN2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :446.9W146
CAS :<p>W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.</p>Formule :C16H27N2O4PDegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :342.37Droloxifene
CAS :<p>Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.</p>Formule :C26H29NO2Degré de pureté :99.86% - 99.97%Couleur et forme :Solid PowderMasse moléculaire :387.51A 419259 trihydrochloride
CAS :<p>A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).</p>Formule :C29H37Cl3N6ODegré de pureté :99.75% - 99.96%Couleur et forme :SolidMasse moléculaire :592NLRP3/AIM2-IN-3
CAS :<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Formule :C16H14N2O2Degré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :266.29TC-DAPK 6
CAS :<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Formule :C17H12N2O2Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :276.29NM-3
CAS :<p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>Formule :C13H12O6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :264.23Mitazalimab
CAS :<p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>Degré de pureté :95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidT025
CAS :<p>T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.</p>Formule :C21H18N8Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :382.42AQ4
CAS :<p>AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.</p>Formule :C22H28N4O4Degré de pureté :96.28% - 97.15%Couleur et forme :SolidMasse moléculaire :412.48
