Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6190 produits trouvés pour "Apoptose"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
BMS-1166 hydrochloride
CAS :"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."Formule :C36H34Cl2N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :677.57CCCI-01
CAS :CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.Formule :C11H9N3O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :247.21BMS-200
CAS :BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.Formule :C27H27F2NO6Couleur et forme :SolidMasse moléculaire :499.5Hetrombopag
CAS :Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.Formule :C25H22N4O5Couleur et forme :SolidMasse moléculaire :458.47DPBQ
CAS :DPBQ (ZINC1620467) is a p53 activator.Formule :C24H14N2O2Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :362.38Ref: TM-T11092
500mgÀ demander1mg100,00€2mg149,00€5mg245,00€10mg354,00€25mg532,00€50mg735,00€100mg982,00€GKK1032B
CAS :GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.Formule :C32H39NO4Couleur et forme :SolidMasse moléculaire :501.66OT-82
CAS :OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Formule :C26H21FN4ODegré de pureté :98.91% - 99.315%Couleur et forme :SolidMasse moléculaire :424.47Ref: TM-T12330
2mg137,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.108,00€100mg1.468,00€HJC-0123
CAS :HJC-0123: inhibits STAT3, boosts cleaved caspase-3, hinders cell growth, triggers apoptosis, effective in ER-negative breast/pancreatic cancer.Formule :C24H16N2O3SCouleur et forme :SolidMasse moléculaire :412.46HDAC8-IN-3
CAS :HDAC8-IN-3 (P19) inhibits HDAC8 (IC50 9.3 μM), induces leukemic cell apoptosis, and enhances thermal stability.Formule :C18H12N4O3S2Couleur et forme :SolidMasse moléculaire :396.44AD-2646
CAS :AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.Formule :C23H40N2O4Couleur et forme :SolidMasse moléculaire :408.57α-NETA
CAS :α-NETA is a ChA inhibitor and an ALDH1A1 and CMKLR1 antagonist with anticancer activity and inhibits cholinesterase and acetylcholinesterase (AChE).Formule :C16H20INODegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :369.24CT-1
CAS :CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
Formule :C29H23F3N4ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :500.51Nimustine
CAS :Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.Formule :C9H13ClN6O2Couleur et forme :SolidMasse moléculaire :272.69MMP2-IN-1
CAS :MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.Formule :C15H13NO5SCouleur et forme :SolidMasse moléculaire :319.33RET-IN-12
CAS :RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).Formule :C30H30F3N5O4Couleur et forme :SolidMasse moléculaire :581.59Simmiparib
CAS :Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.Formule :C23H18F4N6O2Degré de pureté :99.05% - 99.51%Couleur et forme :SolidMasse moléculaire :486.42SAHA-OH
CAS :SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.Formule :C15H22N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.35PK9327
CAS :PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.Formule :C21H22N2SCouleur et forme :SolidMasse moléculaire :334.48MSN-50
CAS :MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.Formule :C36H38BrN3O6Couleur et forme :SolidMasse moléculaire :688.61CMLD010509
CAS :CMLD010509 (SDS-1-021) inhibits oncogenic proteins MDM2, CCND1, MYC, MAF, MCL-1 in multiple myeloma.Formule :C27H26BrNO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.4EC359
CAS :EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.Formule :C36H38F2O2Degré de pureté :98.11% - 98.11%Couleur et forme :SolidMasse moléculaire :540.68Antitumor agent-70
CAS :Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.Formule :C21H18N4O2Couleur et forme :SolidMasse moléculaire :358.39Se-Methylselenocysteine hydrochloride
CAS :Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.Formule :C4H10ClNO2SeDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :218.54PDK4-IN-1
CAS :PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).Formule :C22H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.41Topoisomerase II inhibitor 11
CAS :Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).Formule :C27H21BrCl2N2O2SCouleur et forme :SolidMasse moléculaire :588.34CAM 833
CAS :CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.Formule :C26H26ClFN4O5Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :528.96Topoisomerase I inhibitor 5
CAS :Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.Formule :C24H24N2O2Couleur et forme :SolidMasse moléculaire :372.46(S)-PERK-IN-5
CAS :(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).Formule :C25H26F2N4O3Couleur et forme :SolidMasse moléculaire :468.5PD180970
CAS :PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formule :C21H15Cl2FN4ODegré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :429.27PAK4-IN-2
CAS :PAK4-IN-2 inhibits PAK4 with IC50 2.7 nM, arrests MV4-11 cells at G0/G1, and induces apoptosis, promising for cancer research.Formule :C18H21ClN6Couleur et forme :SolidMasse moléculaire :356.85Aurora kinase-IN-1
Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.Formule :C30H25Br2N3O5Couleur et forme :SolidMasse moléculaire :667.34SMI-6860766
CAS :SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.Formule :C15H11BrClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.61Anticancer agent 57
CAS :Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.Formule :C20H21Cl2NO2Couleur et forme :SolidMasse moléculaire :378.29Verrucarin J
CAS :Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).Formule :C27H32O8Couleur et forme :SolidMasse moléculaire :484.54Filanesib
CAS :Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.Formule :C20H22F2N4O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :420.48Caspase-3/7 activator 3
Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47W1131
CAS :W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.Formule :C23H19N5O4Couleur et forme :SolidMasse moléculaire :429.43XMD15-44
CAS :XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Formule :C29H29F3N4OCouleur et forme :SolidMasse moléculaire :506.56Ferroptosis-IN-4
CAS :Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Formule :C17H24ClN3O2Masse moléculaire :337.84MG-115
CAS :MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.Formule :C25H39N3O5Degré de pureté :97.10%Couleur et forme :White PowderMasse moléculaire :461.59RET-IN-6
CAS :RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).Formule :C30H29N7Couleur et forme :SolidMasse moléculaire :487.6RIPK1-IN-13
CAS :RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.Formule :C21H20ClN3O3Couleur et forme :SolidMasse moléculaire :397.85Xanthine oxidase-IN-6
Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.Formule :C29H34N2O15Couleur et forme :SolidMasse moléculaire :650.58eIF4A3-IN-2
CAS :eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Formule :C25H19Br2ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.71BMS-566394
CAS :BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).Formule :C22H21F3N4O4Couleur et forme :SolidMasse moléculaire :462.42K145
CAS :K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.Formule :C18H24N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.46Tubulin polymerization-IN-24
CAS :HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.Formule :C22H16O3Couleur et forme :SolidMasse moléculaire :328.36Apoptotic agent-3
CAS :"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."Formule :C31H21N5OSCouleur et forme :SolidMasse moléculaire :511.6CTX1
CAS :CTX1 is a small molecule activator of p53.Formule :C14H10N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.26AZM475271
CAS :AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)Formule :C23H27ClN4O3Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :442.94SMU127
CAS :SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer.Formule :C16H23N3O3SCouleur et forme :SolidMasse moléculaire :337.44RIPK1-IN-15
CAS :RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].Formule :C19H19N3O2Couleur et forme :SolidMasse moléculaire :321.37PBOX-15
CAS :PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.Formule :C28H19NO3Couleur et forme :SolidMasse moléculaire :417.46Paclitaxel Ceribate
CAS :Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.Formule :C51H57NO18Couleur et forme :SolidMasse moléculaire :971.99Metoprolol fumarate
CAS :Metoprolol fumarate (CGP 2175C): selective β1-blocker with anti-inflammatory, antitumor, anti-angiogenic effects.Formule :C34H54N2O10Couleur et forme :SolidMasse moléculaire :650.8Ozarelix
CAS :Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.Formule :C72H96ClN17O14Couleur et forme :SolidMasse moléculaire :1459.09APX2009
CAS :APX2009, a 2nd-gen APE1/Ref-1 inhibitor, curbs NFkB activity, survivin, and prostate cancer cell growth; induces cell cycle arrest.Formule :C21H25NO4Couleur et forme :SolidMasse moléculaire :355.43CCT373566
CAS :CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.Formule :C26H29ClF2N6O3Couleur et forme :SolidMasse moléculaire :547YLT205
CAS :YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.Formule :C16H12BrClN4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.78F5446
CAS :F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Formule :C26H17ClN2O8SDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :552.94HDAC-IN-31
CAS :HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.Formule :C25H24N4O2Couleur et forme :SolidMasse moléculaire :412.48Trehalose 6-behenate
CAS :Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.Formule :C34H64O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :664.86Shield-2
CAS :Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.Formule :C35H51N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.8CMLD012073
CAS :CMLD012073: Potent eIF4A inhibitor, halts eukaryotic translation; IC50 10 nM in NIH/3T3 cells.Formule :C30H30N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :530.57PARP1/BRD4-IN-1
CAS :PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.Formule :C29H26N6O3Couleur et forme :SolidMasse moléculaire :506.56Apogossypolone (ApoG2)
CAS :Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K iFormule :C28H26O8Couleur et forme :SolidMasse moléculaire :490.5AMPK activator 11
CAS :AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Formule :C25H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.45DB2313 HCl
CAS :DB2313: first-in-class, potent inhibitor of PU.1, disrupts gene interactions, down-regulates PU.1 targets.Formule :C42H45Cl4FN8O2Couleur et forme :SolidMasse moléculaire :854.67AG6033
CAS :AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.Formule :C30H23N5O4Couleur et forme :SolidMasse moléculaire :517.53RIPK1-IN-11
CAS :RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Formule :C23H24N4O4SCouleur et forme :SolidMasse moléculaire :452.53D-Cl-amidine
CAS :D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.Formule :C14H19ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.78EGFR-IN-88
CAS :EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormule :C22H18Cl2N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.37ZDLD13
CAS :ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.Formule :C18H14N4OCouleur et forme :SolidMasse moléculaire :302.33VEGFR-2-IN-23
CAS :VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Formule :C22H15N5O2Couleur et forme :SolidMasse moléculaire :381.39Anticancer agent 76
CAS :Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.Formule :C32H33NO5SCouleur et forme :SolidMasse moléculaire :543.67Rooperol
CAS :Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.Formule :C17H14O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.29MMP-9-IN-5
CAS :MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.Formule :C27H20IN3O4Couleur et forme :SolidMasse moléculaire :577.37PD-1-IN-18
CAS :PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.Formule :C11H17N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.28Tubulin polymerization-IN-22
CAS :Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.Formule :C19H16O4Couleur et forme :SolidMasse moléculaire :308.33NF-κB-IN-5
CAS :NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.Formule :C23H27N3O4Couleur et forme :SolidMasse moléculaire :409.48PD-1/PD-L1-IN-25
CAS :"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."Formule :C26H24ClN3O5Couleur et forme :SolidMasse moléculaire :493.94DRAK2-IN-1
CAS :Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.41KU-0058948
CAS :KU-0058948: PARP inhibitor, triggers cell cycle arrest and apoptosis in myeloid leukemia cells in vitro.Formule :C21H21FN4O2Couleur et forme :SolidMasse moléculaire :380.42Topoisomerase I inhibitor 3
CAS :Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.Formule :C18H14FNO3Couleur et forme :SolidMasse moléculaire :311.31GLS1 Inhibitor-4
CAS :GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.Formule :C29H27F3N10O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.72LSD1-IN-14
CAS :LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.Formule :C21H24FN5Couleur et forme :SolidMasse moléculaire :365.45BJE6-106
CAS :BJE6-106, Selective PKCδ inhibitor (IC50=0.05 μM), induces caspase-dependent apoptosis, activates JNK/H2AX, for NRAS-mutated melanoma.Formule :C26H23NO2Couleur et forme :SolidMasse moléculaire :381.47SGC-STK17B-1
CAS :SGC-STK17B-1 is a potent and selective inhibitor of STK17B/DRAK2 kinase.Formule :C16H10N2O2S3Couleur et forme :SolidMasse moléculaire :358.46ISC-4
CAS :ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.Formule :C11H13NSeCouleur et forme :SolidMasse moléculaire :238.19DRAK1/2-IN-1
CAS :DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.Formule :C22H24N2O3SCouleur et forme :SolidMasse moléculaire :396.5Antitumor agent-44
CAS :Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in humanFormule :C24H15N3O3Couleur et forme :SolidMasse moléculaire :393.39Isodispar B
CAS :Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.Formule :C20H18O5Couleur et forme :SolidMasse moléculaire :338.35PI3K-IN-34
CAS :PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.Formule :C23H22N6O3Couleur et forme :SolidMasse moléculaire :430.46hGGPPS-IN-1
CAS :HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.Formule :C13H13N3O6P2SCouleur et forme :SolidMasse moléculaire :401.27IST5-002
CAS :IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.Formule :C17H20N5O7PDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :437.34Nafamostat hydrochloride
CAS :Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.Formule :C19H19Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.29Gemcitabine monophosphate
CAS :R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.Formule :C9H12F2N3O7PCouleur et forme :SolidMasse moléculaire :343.18hCAIX-IN-12
CAS :hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.Formule :C18H14N4O3S2Couleur et forme :SolidMasse moléculaire :398.46CAY10747
CAS :CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.Formule :C42H48FNO6Couleur et forme :SolidMasse moléculaire :681.83Bisindolylmaleimide VIII
CAS :Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.
Formule :C24H22N4O2Degré de pureté :97% - 98.01%Couleur et forme :SolidMasse moléculaire :398.46
