Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6223 produits trouvés pour "Apoptose"
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PI3K/Akt/mTOR-IN-2
CAS :Potent PI3K/AKT/mTOR inhibitor, selective for MDA-MB-231 cells with IC50 of 2.29 μM; induces arrest and apoptosis.Formule :C17H13F2NODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :285.29Ref: TM-T60564
1mg37,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg124,00€25mg255,00€50mg409,00€100mg602,00€500mg1.279,00€BR102375
CAS :BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.Formule :C31H34N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.64Flonoltinib
CAS :Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.Formule :C25H34FN7ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :467.58Antitumor agent-55
CAS :Antitumor agent-55 (5q) inhibits PC3 (IC50: 0.91 μM), blocks G1/S phase, induces apoptosis, and halts migration.Formule :C32H34N6O4SCouleur et forme :SolidMasse moléculaire :598.72CA224
CAS :CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.Formule :C24H22N2OCouleur et forme :SolidMasse moléculaire :354.44NKP-1339
CAS :NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Formule :C14H12Cl4N4NaRuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.14Vin-F03
CAS :Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.Formule :C22H29N3Couleur et forme :SolidMasse moléculaire :335.49AZD-5991 Racemate
CAS :AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.Formule :C35H34ClN5O3S2Couleur et forme :SolidMasse moléculaire :672.26N1,N11-Diethylnorspermine
CAS :DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.Formule :C13H32N4Couleur et forme :SolidMasse moléculaire :244.42Mcl1-IN-11
CAS :Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.Formule :C38H41N3O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :683.88Bcl-2-IN-9
CAS :Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.Formule :C27H31N7O3SCouleur et forme :SolidMasse moléculaire :533.65STAT3-IN-10
CAS :STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).Formule :C17H13NO5Couleur et forme :SolidMasse moléculaire :311.29LLL3
CAS :LLL3 is a small molecule STAT3 inhibitor.Formule :C16H10O4Couleur et forme :SolidMasse moléculaire :266.25MMPSI
CAS :MMPSI (Caspase-3/7 Inhibitor I) is a caspase 3 and caspase 7 inhibitor that inhibits ischemic injury in cardiomyocytes and can be used to study cardioprotectionFormule :C14H16N2O5SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :324.35PDK4-IN-1
CAS :PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).Formule :C22H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.41DC-CPin711
CAS :DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.Formule :C23H22N4O2Couleur et forme :SolidMasse moléculaire :386.45Mcl1-IN-4
CAS :Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formule :C28H26N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.58CRA-026440
CAS :CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7Formule :C23H24N4O4Degré de pureté :96.42%Couleur et forme :SolidMasse moléculaire :420.46VEGFR-2-IN-22
CAS :VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.Formule :C26H24ClFN4O6Couleur et forme :SolidMasse moléculaire :542.94BRD4 Inhibitor-15
CAS :BRD4 Inhibitor-15 targets BRD4 with 18 nM IC50, induces apoptosis in 22RV1 cells, and lowers c-Myc, aiding prostate cancer research.Formule :C22H21N3O2Couleur et forme :SolidMasse moléculaire :359.42c-Fms-IN-12
CAS :c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.Formule :C30H32N6O6Couleur et forme :SolidMasse moléculaire :572.61IHMT-TRK-284
CAS :IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Formule :C25H27N7OSCouleur et forme :SolidMasse moléculaire :473.59PARP-1-IN-2
CAS :PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against
Formule :C22H15Cl2N3O2Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :424.28Prexasertib mesylate
CAS :Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.Formule :C19H23N7O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.49p53 Activator 3
CAS :Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formule :C30H37F3N4O4SCouleur et forme :SolidMasse moléculaire :606.7BIBU-1361 dihydrochloride
CAS :BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.Formule :C22H29Cl3FN7Couleur et forme :SolidMasse moléculaire :516.87ANO1-IN-3
CAS :ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].Formule :C20H17NO3Couleur et forme :SolidMasse moléculaire :319.35ABT-100
CAS :ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.Formule :C27H19F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.46SCAL-255
CAS :SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.Formule :C27H28F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.54Rohinitib
CAS :Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.Formule :C29H31NO8Couleur et forme :SolidMasse moléculaire :521.56VRT-043198
CAS :VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.Formule :C22H29ClN4O6Couleur et forme :SolidMasse moléculaire :480.94CDK1/Cyc B-IN-1
CAS :CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.Formule :C14H12ClN3O2S2Couleur et forme :SolidMasse moléculaire :353.85JMX0293
JMX0293, a salicylamide derivative, inhibits STAT3, inducing MDA-MB-231 cell apoptosis with IC50=3.38μM, while sparing MCF-10A (IC50>60μM).Formule :C25H30Cl2N4O7Couleur et forme :SolidMasse moléculaire :569.43SDZ 224-015
CAS :SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.Formule :C30H35Cl2N3O9Degré de pureté :95.49% - 95.49%Couleur et forme :SolidMasse moléculaire :652.52n-Octyl caffeate
CAS :n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.Formule :C17H24O4Couleur et forme :SolidMasse moléculaire :292.37CAY10682
CAS :(±)-Nutlin-3 & CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).Formule :C30H25BrFN5OCouleur et forme :SolidMasse moléculaire :570.45RI-962
CAS :RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.Formule :C28H28N6O2Degré de pureté :99.39%Couleur et forme :SoildMasse moléculaire :480.56Tubulin inhibitor 23
CAS :Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.Formule :C26H23NO6SCouleur et forme :SolidMasse moléculaire :477.53PC-046
CAS :PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).Formule :C22H18N2O3Couleur et forme :SolidMasse moléculaire :358.39ARN5187 trihydrochloride
CAS :ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.Formule :C24H35Cl3FN3OCouleur et forme :SolidMasse moléculaire :506.912Epofolate
CAS :Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.Formule :C67H92N16O22S3Couleur et forme :SolidMasse moléculaire :1569.74LWG-301
LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.Formule :C28H38N8O3SCouleur et forme :SolidMasse moléculaire :566.72JS-K
CAS :JS-K is a Nitric oxide donor. It has antiproliferative activity.Formule :C13H16N6O8Couleur et forme :SolidMasse moléculaire :384.3Obatoclax
CAS :Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.Formule :C20H19N3ODegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :317.38Talaporfin free acid
CAS :Talaporfin, an effective tumor localizer, can produce the selective degradation of tumor tissue following light exposure.Formule :C38H41N5O9Couleur et forme :SolidMasse moléculaire :711.76Nevanimibe
CAS :Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).Formule :C27H39N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.62AS1708727
CAS :AS1708727 is an orally bioavailable FOXO1 inhibitor that reduces plasma glucose and triglyceride levels in diabetic mice.Formule :C24H24Cl2N2O2Couleur et forme :SolidMasse moléculaire :443.37PARP1-IN-10
CAS :PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.Formule :C20H23N3O5Couleur et forme :SolidMasse moléculaire :385.41PI3Kα-IN-6
CAS :PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.Formule :C16H15IN2OSCouleur et forme :SolidMasse moléculaire :410.27EGFR-IN-88
CAS :EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormule :C22H18Cl2N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.37MDM2-p53-IN-16
CAS :MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.Formule :C32H33N3O5Couleur et forme :SolidMasse moléculaire :539.62Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Formule :C29H30N6O2Couleur et forme :SolidMasse moléculaire :494.59CAY10506
CAS :CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.Formule :C20H26N2O4S3Couleur et forme :SolidMasse moléculaire :454.63Mutant p53 modulator-1
CAS :Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.Formule :C27H32F4N8O2Couleur et forme :SolidMasse moléculaire :576.59CCT373566
CAS :CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.Formule :C26H29ClF2N6O3Couleur et forme :SolidMasse moléculaire :547RIP1 kinase inhibitor 6
CAS :RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1Formule :C19H18F2N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.35Apoptotic agent-3
CAS :"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."Formule :C31H21N5OSCouleur et forme :SolidMasse moléculaire :511.6Tubulin/HDAC-IN-1
CAS :Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.Formule :C21H18N4O3Couleur et forme :SolidMasse moléculaire :374.39T-3256336
CAS :T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formule :C31H45F2N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.72K145
CAS :K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.Formule :C18H24N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.46BMS-566394
CAS :BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).Formule :C22H21F3N4O4Couleur et forme :SolidMasse moléculaire :462.42Pentabromophenol
CAS :Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.Formule :C6HBr5ODegré de pureté :99.83%Couleur et forme :Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)Masse moléculaire :488.59RIPK1-IN-3
CAS :RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.Formule :C22H19F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.42p53 Activator 2
CAS :p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.Formule :C20H21N5O2Couleur et forme :SolidMasse moléculaire :363.41Aurora kinase-IN-1
Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.Formule :C30H25Br2N3O5Couleur et forme :SolidMasse moléculaire :667.34Irbesartan HCl
CAS :Irbesartan: angiotensin II blocker; treats hypertension by inhibiting receptor binding.Formule :C25H29ClN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :465K-7174 dihydrochloride
CAS :K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-Formule :C33H50Cl2N2O6Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :641.67Erasin
Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.Formule :C20H19N3O3Couleur et forme :SolidMasse moléculaire :349.38Psammaplysene A
CAS :Psammaplysene A is a FOXO1a nuclear export inhibitor.Formule :C27H35Br4N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :769.2SAHA-OH
CAS :SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.Formule :C15H22N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.35MpsBAY2a
CAS :carcinoma cell proliferation.Formule :C29H28N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.57PD-1-IN-22
CAS :PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).Formule :C25H25N5O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :459.5Ref: TM-T12379
1mg109,00€2mg163,00€5mg243,00€1mL*10mM (DMSO)284,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€ATSP-7041
CAS :ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)Formule :C87H125N17O21Couleur et forme :SolidMasse moléculaire :1745.02GEM144
CAS :GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.Formule :C28H31NO5Couleur et forme :SolidMasse moléculaire :461.55BMS-37
CAS :BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.Formule :C27H32N2O4Couleur et forme :SolidMasse moléculaire :448.55Cadein1
Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.Formule :C33H48F2INO2Couleur et forme :SolidMasse moléculaire :655.64MBM-17
CAS :MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).Formule :C28H28N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.56Anticancer agent 83
CAS :Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.Formule :C20H19N5OSCouleur et forme :SolidMasse moléculaire :377.46KY1022
CAS :KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.Formule :C17H19N3OSCouleur et forme :SolidMasse moléculaire :313.42c-Met-IN-14
CAS :c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.Formule :C34H38ClFN4O7SCouleur et forme :SolidMasse moléculaire :701.2LLP-3
CAS :Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.Formule :C32H23ClN2O4Couleur et forme :SolidMasse moléculaire :534.99EGFR-IN-56
CAS :EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.Formule :C23H22N4O3SCouleur et forme :SolidMasse moléculaire :434.51HS-438
CAS :HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.Formule :C17H17N3O3SCouleur et forme :SolidMasse moléculaire :343.4Antioxidant agent-5
CAS :Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.Formule :C24H24N6OCouleur et forme :SolidMasse moléculaire :412.49ADU-S100
CAS :ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.Formule :C20H24N10O10P2S2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :690.54HDACs/mTOR Inhibitor 1
CAS :HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,Formule :C28H38N8O5Couleur et forme :SolidMasse moléculaire :566.65EGFR-IN-60
CAS :EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.Formule :C28H28Cl2N6OCouleur et forme :SolidMasse moléculaire :535.47DBIBB
CAS :DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.Formule :C23H20N2O6SDegré de pureté :98.49% - 99.1%Couleur et forme :SolidMasse moléculaire :452.48Ref: TM-T22070
1mg39,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg127,00€25mg250,00€50mg358,00€100mg525,00€500mg1.054,00€TRK-IN-23
CAS :TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,Formule :C20H17FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.37PD-1/PD-L1-IN-28
CAS :PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.Formule :C24H24N4O2Couleur et forme :SolidMasse moléculaire :400.47Anticancer agent 72
CAS :Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.Formule :C20H19N7O2Couleur et forme :SolidMasse moléculaire :389.41Mcl1-IN-3
CAS :Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.Formule :C27H22ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.93Epinephrine bitartrate
CAS :L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.Formule :C13H19NO9Degré de pureté :99.07% - 99.94%Couleur et forme :White SolidMasse moléculaire :333.3ENMD-1068 HCl
CAS :ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.Formule :C15H29N3O2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :283.417DG
CAS :7DG is a selective inhibitor of protein kinase R (PKR).Formule :C26H30O5Couleur et forme :SolidMasse moléculaire :422.51IM-93
CAS :IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formule :C21H28N4O2Couleur et forme :SolidMasse moléculaire :368.47Anti-inflammatory agent 22
CAS :Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.Formule :C22H16O6Couleur et forme :SolidMasse moléculaire :376.36VO-OHPic
CAS :VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.Formule :C12H10N2O8VCouleur et forme :SolidMasse moléculaire :361.16Anticancer agent 42
CAS :Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.Formule :C19H16Cl2N2O3Couleur et forme :SolidMasse moléculaire :391.25GGTI-2154
CAS :GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity againstFormule :C24H28N4O3Couleur et forme :SolidMasse moléculaire :420.5
