Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6190 produits trouvés pour "Apoptose"
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GDP366
CAS :GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.Formule :C20H17N5OSDegré de pureté :98.78% - 99.84%Couleur et forme :SolidMasse moléculaire :375.45NSC260594
CAS :NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-Formule :C29H24N6O3Couleur et forme :SolidMasse moléculaire :504.54IM-54
CAS :IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.Formule :C19H23N3O2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :325.4S130
CAS :S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.Formule :C24H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.47KRAS G12D inhibitor 14
CAS :KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM).Formule :C20H19F3N4OSDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :420.45CMLD012073
CAS :CMLD012073: Potent eIF4A inhibitor, halts eukaryotic translation; IC50 10 nM in NIH/3T3 cells.Formule :C30H30N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :530.57CEP-40125
CAS :CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.Formule :C28H45Cl2N3O2Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :526.58Topoisomerase II inhibitor 3
CAS :Acridone-based Topoisomerase II inhibitor 3 targets topo IIα/β (IC50: 0.17μM α, 0.23μM β), causes DNA damage, and induces apoptosis.Formule :C18H20N4O4Couleur et forme :SolidMasse moléculaire :356.38Tezacitabine
CAS :Tezacitabine, a nucleoside analogue, inhibits ribonucleotide reductase, disrupts DNA replication, and induces apoptosis in tumor cells.Formule :C10H12FN3O4Couleur et forme :SolidMasse moléculaire :257.22RET-IN-12
CAS :RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).Formule :C30H30F3N5O4Couleur et forme :SolidMasse moléculaire :581.59Antitumor agent-44
CAS :Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in humanFormule :C24H15N3O3Couleur et forme :SolidMasse moléculaire :393.39BR102375
CAS :BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.Formule :C31H34N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.64Flonoltinib
CAS :Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.Formule :C25H34FN7ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :467.58NKP-1339
CAS :NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.Formule :C14H12Cl4N4NaRuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.14N1,N11-Diethylnorspermine
CAS :DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.Formule :C13H32N4Couleur et forme :SolidMasse moléculaire :244.42VMY-1-103
CAS :VMY-1-103: a strong CDK inhibitor better than purvalanol B; halts prostate/breast cancer cell growth, induces apoptosis, may treat medulloblastoma.Formule :C34H42ClN9O4SCouleur et forme :SolidMasse moléculaire :708.27DC-CPin711
CAS :DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.Formule :C23H22N4O2Couleur et forme :SolidMasse moléculaire :386.45Didesmethylrocaglamide
CAS :Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,Formule :C27H27NO7Couleur et forme :SolidMasse moléculaire :477.51Mcl1-IN-4
CAS :Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formule :C28H26N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.58PDGFR-IN-1
CAS :PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formule :C25H30N8ODegré de pureté :99.13% - 99.49%Couleur et forme :SolidMasse moléculaire :458.56Ref: TM-T62872
1mg170,00€5mg432,00€1mL*10mM (DMSO)434,00€10mg655,00€25mg1.153,00€50mg1.665,00€100mg2.250,00€BRD4 Inhibitor-15
CAS :BRD4 Inhibitor-15 targets BRD4 with 18 nM IC50, induces apoptosis in 22RV1 cells, and lowers c-Myc, aiding prostate cancer research.Formule :C22H21N3O2Couleur et forme :SolidMasse moléculaire :359.42IHMT-TRK-284
CAS :IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Formule :C25H27N7OSCouleur et forme :SolidMasse moléculaire :473.59LY5
CAS :LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.Formule :C15H11N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.33PD180970
CAS :PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formule :C21H15Cl2FN4ODegré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :429.27PARP-1-IN-2
CAS :PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against
Formule :C22H15Cl2N3O2Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :424.28Verrucarin J
CAS :Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).Formule :C27H32O8Couleur et forme :SolidMasse moléculaire :484.54RIPK1-IN-15
CAS :RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].Formule :C19H19N3O2Couleur et forme :SolidMasse moléculaire :321.37CDK1/Cyc B-IN-1
CAS :CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.Formule :C14H12ClN3O2S2Couleur et forme :SolidMasse moléculaire :353.85SDZ 224-015
CAS :SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.Formule :C30H35Cl2N3O9Degré de pureté :95.49% - 95.49%Couleur et forme :SolidMasse moléculaire :652.52Epofolate
CAS :Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.Formule :C67H92N16O22S3Couleur et forme :SolidMasse moléculaire :1569.74PI3Kα-IN-6
CAS :PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.Formule :C16H15IN2OSCouleur et forme :SolidMasse moléculaire :410.27Dipin
CAS :Dipin is an Antineoplastic.Formule :C12H24N6O2P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :346.31Atopaxar
CAS :Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formule :C29H38FN3O5Degré de pureté :97.07% - 98.07%Couleur et forme :SolidMasse moléculaire :527.63CAY10506
CAS :CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.Formule :C20H26N2O4S3Couleur et forme :SolidMasse moléculaire :454.63Mutant p53 modulator-1
CAS :Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.Formule :C27H32F4N8O2Couleur et forme :SolidMasse moléculaire :576.59QM31
CAS :QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).Formule :C39H38Cl4N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :768.56RET-IN-8
CAS :RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.Formule :C27H30N6O3Couleur et forme :SolidMasse moléculaire :486.57Sanazole
CAS :Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.Formule :C7H11N5O4Couleur et forme :SolidMasse moléculaire :229.19Tubulin/HDAC-IN-1
CAS :Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.Formule :C21H18N4O3Couleur et forme :SolidMasse moléculaire :374.39T-3256336
CAS :T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formule :C31H45F2N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.72Pentabromophenol
CAS :Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.Formule :C6HBr5ODegré de pureté :99.83%Couleur et forme :Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)Masse moléculaire :488.59RIPK1-IN-3
CAS :RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.Formule :C22H19F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.42(E)-[6]-Dehydroparadol
CAS :(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.Formule :C17H24O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :276.37Ref: TM-T13436
2mg34,00€1mg42,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg73,00€25mg122,00€50mg166,00€100mg231,00€500mg872,00€DJ001
CAS :DJ001: specific PTPσ inhibitor, non-competitive, IC50=1.43 μM, aids hematopoietic stem cell regeneration.Formule :C15H12N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :268.27Ref: TM-T11053
1mg39,00€1mL*10mM (DMSO)87,00€5mg89,00€10mg124,00€25mg198,00€50mg280,00€100mg376,00€200mg520,00€W146 TFA
CAS :W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.Formule :C18H28F3N2O6PCouleur et forme :SolidMasse moléculaire :456.399MYRA-A
CAS :MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.Formule :C19H20N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.37pan-HER-IN-1
CAS :Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.Formule :C19H14BrN5OCouleur et forme :SolidMasse moléculaire :408.25MpsBAY2a
CAS :carcinoma cell proliferation.Formule :C29H28N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.57NSC405640
CAS :NSC405640 selectively inhibits MDM2-p53 interaction, restoring mutated p53 structure; halts growth of cells with normal p53. [1]Formule :C12H10Cl2SnCouleur et forme :SolidMasse moléculaire :343.82HL271
CAS :HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.Formule :C13H17ClF3N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.76Topoisomerase IIα-IN-3
CAS :Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.Formule :C29H20N6O2SCouleur et forme :SolidMasse moléculaire :516.57EGFR-IN-56
CAS :EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.Formule :C23H22N4O3SCouleur et forme :SolidMasse moléculaire :434.51Adapalene sodium salt
CAS :Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.Formule :C28H28NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.519CDK1/2/4-IN-1
CAS :CDK1/2/4-IN-1 inhibits CDKs (IC50: CDK1-1.47μM; CDK2-0.78μM; CDK4-0.87μM) and is useful in cancer studies, affecting apoptosis and the cell cycle.Formule :C15H16N2O2SCouleur et forme :SolidMasse moléculaire :288.36HDACs/mTOR Inhibitor 1
CAS :HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,Formule :C28H38N8O5Couleur et forme :SolidMasse moléculaire :566.65SKI-I
CAS :SKI-I: Human sphingosine kinase inhibitor, IC50 1.2μM; hERK2 inhibitor, IC50 11μM; promotes tumor cell apoptosis.Formule :C25H18N4O2Couleur et forme :SolidMasse moléculaire :406.44SID 3712249
CAS :SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).Formule :C17H21N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.4FW1256
CAS :FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.Formule :C12H10NOPSCouleur et forme :SolidMasse moléculaire :247.25MPT0B392
CAS :MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.Formule :C19H20N2O6SCouleur et forme :SolidMasse moléculaire :404.44AMC-01
CAS :AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51.Formule :C27H27BrN2O6Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :555.42MBM-17S
CAS :MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest andFormule :C36H40N6O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :716.74ARN5187
CAS :ARN5187, a lysosomal REV-ERB β ligand, inhibits transcription and autophagy, shows efficacy, cytotoxicity, and induces apoptosis.Formule :C24H32FN3OCouleur et forme :SolidMasse moléculaire :397.53S65487
CAS :S65487 (VOB560) inhibits Bcl-2, including G101V and D103Y variants, while sparing MCL-1, BFL-1, and BCL-XL, supporting its anticancer potential.Formule :C41H41ClN6O4Degré de pureté :99.034%Couleur et forme :SolidMasse moléculaire :717.26Apoptosis inducer 10
CAS :Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity.Formule :C27H46N2O2Couleur et forme :SolidMasse moléculaire :430.67MI-192
CAS :MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.Formule :C24H21N3O2Couleur et forme :SolidMasse moléculaire :383.44MIR002
CAS :MIR002: an oral POLA1/HDAC11 inhibitor with antitumor effects, enhances p53/p21, causes G1/S arrest, and triggers apoptosis.Formule :C27H29NO5Couleur et forme :SolidMasse moléculaire :447.52RIPK3-IN-2
CAS :RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.Formule :C21H16ClN3O2S2Couleur et forme :SolidMasse moléculaire :441.95CSRM617
CAS :CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.Formule :C10H13N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :255.23BJE6-106
CAS :BJE6-106, Selective PKCδ inhibitor (IC50=0.05 μM), induces caspase-dependent apoptosis, activates JNK/H2AX, for NRAS-mutated melanoma.Formule :C26H23NO2Couleur et forme :SolidMasse moléculaire :381.47ZDLD13
CAS :ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.Formule :C18H14N4OCouleur et forme :SolidMasse moléculaire :302.33AG-024322
CAS :AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.Formule :C23H20F2N6Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :418.44D-Cl-amidine
CAS :D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.Formule :C14H19ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.78Ivaltinostat
CAS :CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.Formule :C24H33N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.54SKF1
CAS :SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.Formule :C23H37ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.01MG-115
CAS :MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.Formule :C25H39N3O5Degré de pureté :97.10%Couleur et forme :White PowderMasse moléculaire :461.59VEGFR-2-IN-19
CAS :VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.Formule :C21H19N3O2Couleur et forme :SolidMasse moléculaire :345.39BPTQ
CAS :BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.Formule :C17H16N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.4SMI-6860766
CAS :SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.Formule :C15H11BrClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.61Merck-22-6
CAS :Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.Formule :C40H43N7O2Couleur et forme :SolidMasse moléculaire :653.82HS56
CAS :HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.Formule :C13H8ClN5OSCouleur et forme :SolidMasse moléculaire :317.75OT-82
CAS :OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Formule :C26H21FN4ODegré de pureté :98.91% - 99.315%Couleur et forme :SolidMasse moléculaire :424.47Ref: TM-T12330
2mg137,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg708,00€50mg1.108,00€100mg1.468,00€BMS-1166 hydrochloride
CAS :"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."Formule :C36H34Cl2N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :677.57HDAC-IN-39
CAS :HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.Formule :C27H26N4O4SCouleur et forme :SolidMasse moléculaire :502.58Flupenthixol
CAS :Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.Formule :C23H25F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.52SHP2-IN-8
CAS :SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.Formule :C17H21Cl2N5SCouleur et forme :SolidMasse moléculaire :398.35NMK-TD-100
CAS :NMK-TD-100: Microtubule disruptor, anti-proliferative, blocks mitosis, causes apoptosis in HeLa; IC50=17.5µM for tubulin polymerization.Formule :C19H17N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.42Anticancer agent 32
CAS :Compound 2g, an anticancer agent, disrupts cell cycle and induces apoptosis for cancer research.Formule :C24H21F2N5OCouleur et forme :SolidMasse moléculaire :433.45Perillic acid
CAS :Perillic acid, a perillyl alcohol metabolite, induces lung cancer cell arrest, apoptosis, and has anti-HSV-1 and immune-modulating effects.Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22BTK-IN-24
CAS :BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.Formule :C26H19F4N5O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :509.46IMM-H004
CAS :IMM-H004 is an effective inhibitor of BV2 microglia activation.Formule :C16H20N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.34Antitumor agent-62
CAS :Antitumor agent-62 releases NO, inhibits cancer cell growth, triggers apoptosis, and halts cell cycle at G2/M.Formule :C21H19N3O9SCouleur et forme :SolidMasse moléculaire :489.46HDAC-IN-36
CAS :HDAC-IN-36: Oral HDAC6 inhibitor, IC50 = 11.68 nM, promotes apoptosis & autophagy, anti-tumor & anti-metastatic, for breast cancer research.Formule :C29H39N5O5Couleur et forme :SolidMasse moléculaire :537.65PD-1/PD-L1-IN 6
CAS :Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.Formule :C25H26N2O3Couleur et forme :SolidMasse moléculaire :402.49IZTZ-1
CAS :IZTZ-1: c-MYC G4 stabilizer, reduces expression, blocks cell cycle, induces apoptosis, inhibits B16 melanoma growth.Formule :C32H35N7SCouleur et forme :SolidMasse moléculaire :549.73CFM-5
CAS :CFM-5 has anticonvulsant activity and is used in epilepsy research.Formule :C23H18BrN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.38NSC10010 hydrochloride
CAS :NSC10010 inhibits gammaherpesvirus B-lymphomas by activating NF-κB and c-Myc pathways.Formule :C31H42Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.60RIP1 kinase inhibitor 5
CAS :RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) inFormule :C13H17F2NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :257.283-(3-Phenoxybenzyl)amino-β-carboline
CAS :3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.Formule :C24H19N3OCouleur et forme :SolidMasse moléculaire :365.43Sibiriline
CAS :Sibiriline is a Receptor-Interacting Protein Kinase 1 inhibitor that acts by preventing immune-dependent hepatitis.Formule :C13H10N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :210.23RS6212
CAS :RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.Formule :C20H22N4O3SCouleur et forme :SolidMasse moléculaire :398.48
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