Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(92 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6188 produits trouvés pour "Apoptose"
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GEM144
CAS :GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.Formule :C28H31NO5Couleur et forme :SolidMasse moléculaire :461.55ATSP-7041
CAS :ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)Formule :C87H125N17O21Couleur et forme :SolidMasse moléculaire :1745.02Anticancer agent 77
CAS :Anticancer agent 77 exhibits anticancer effects and can be used extensively in synthetic and medicinal chemistry studies.Formule :C25H30BrN7Couleur et forme :SolidMasse moléculaire :508.46p53 Activator 5
CAS :Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formule :C29H32F6N4OCouleur et forme :SolidMasse moléculaire :566.58CCCI-01
CAS :CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.Formule :C11H9N3O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :247.21PI3K inhibitor C 96
CAS :PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.Formule :C11H8N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.26Semapimod
CAS :Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.Formule :C34H52N18O2Couleur et forme :SolidMasse moléculaire :744.9PD173952
CAS :PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.Formule :C24H21Cl2N5O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :482.36Thioxodihydroquinazolinone-19
CAS :Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.Formule :C16H14N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.36Anticancer agent 99
CAS :Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.Formule :C19H20F3N3O2Couleur et forme :SolidMasse moléculaire :379.38IST5-002
CAS :IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.Formule :C17H20N5O7PDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :437.34Didesmethylrocaglamide
CAS :Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,Formule :C27H27NO7Couleur et forme :SolidMasse moléculaire :477.51Aurora kinase-IN-1
Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.Formule :C30H25Br2N3O5Couleur et forme :SolidMasse moléculaire :667.34Mcl1-IN-4
CAS :Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formule :C28H26N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.58RIPK1-IN-13
CAS :RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.Formule :C21H20ClN3O3Couleur et forme :SolidMasse moléculaire :397.85D-Cl-amidine
CAS :D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.Formule :C14H19ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.78Topoisomerase I inhibitor 5
CAS :Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.Formule :C24H24N2O2Couleur et forme :SolidMasse moléculaire :372.46Aurora A inhibitor 2
CAS :Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).Formule :C24H26N6O3Couleur et forme :SolidMasse moléculaire :446.5BMS-566394
CAS :BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).Formule :C22H21F3N4O4Couleur et forme :SolidMasse moléculaire :462.42K145
CAS :K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.Formule :C18H24N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.46VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.Formule :C26H20Cl2F3N5O3S2Couleur et forme :SolidMasse moléculaire :642.5BCL6-IN-8c
CAS :BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbentFormule :C20H20ClN3O5Couleur et forme :SolidMasse moléculaire :417.84CYD-2-11
CAS :CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.Formule :C22H18N2O3Couleur et forme :SolidMasse moléculaire :358.39CB-64D
CAS :CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.Formule :C22H23NO2Couleur et forme :SolidMasse moléculaire :333.42Apoptotic agent-3
CAS :"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."Formule :C31H21N5OSCouleur et forme :SolidMasse moléculaire :511.6CCT373566
CAS :CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.Formule :C26H29ClF2N6O3Couleur et forme :SolidMasse moléculaire :547ZDLD13
CAS :ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.Formule :C18H14N4OCouleur et forme :SolidMasse moléculaire :302.33MR2938
CAS :MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.Formule :C21H24N4O3Couleur et forme :SolidMasse moléculaire :380.44YLT205
CAS :YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.Formule :C16H12BrClN4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.78AP23464
CAS :AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.Formule :C26H30N5O2PDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :475.52MDM2-p53-IN-16
CAS :MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.Formule :C32H33N3O5Couleur et forme :SolidMasse moléculaire :539.62VMY-1-103
CAS :VMY-1-103: a strong CDK inhibitor better than purvalanol B; halts prostate/breast cancer cell growth, induces apoptosis, may treat medulloblastoma.Formule :C34H42ClN9O4SCouleur et forme :SolidMasse moléculaire :708.27Antitumor agent-57
CAS :Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.Formule :C20H15NO5Couleur et forme :SolidMasse moléculaire :349.34EGFR/HER2/TS-IN-1
CAS :EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.Formule :C24H15N5O4S2Couleur et forme :SolidMasse moléculaire :501.54EGFR-IN-88
CAS :EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormule :C22H18Cl2N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.37Bcl-2/Mcl-1-IN-1
CAS :Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.Formule :C28H23NO3Couleur et forme :SolidMasse moléculaire :421.49VEGFR-2-IN-23
CAS :VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Formule :C22H15N5O2Couleur et forme :SolidMasse moléculaire :381.39Bisindolylmaleimide VIII
CAS :Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.
Formule :C24H22N4O2Degré de pureté :97% - 98.01%Couleur et forme :SolidMasse moléculaire :398.46L6H21
CAS :L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.Formule :C18H18O4Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :298.33Tubulin polymerization-IN-22
CAS :Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.Formule :C19H16O4Couleur et forme :SolidMasse moléculaire :308.33NF-κB-IN-5
CAS :NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.Formule :C23H27N3O4Couleur et forme :SolidMasse moléculaire :409.48CDK6/PIM1-IN-1
CAS :CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.Formule :C25H28FN9Couleur et forme :SolidMasse moléculaire :473.55TPB15
CAS :TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.Formule :C18H9Cl4N5OCouleur et forme :SolidMasse moléculaire :453.11Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Formule :C26H23NOCouleur et forme :SolidMasse moléculaire :365.47CK2/ERK8-IN-1
CAS :TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.Formule :C11H9Br4N3O2Degré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :534.82IDH1 Inhibitor 9
CAS :IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.Formule :C26H30N4O3Couleur et forme :SolidMasse moléculaire :446.54GLS1 Inhibitor-4
CAS :GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.Formule :C29H27F3N10O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.72CMC2.24
CAS :CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.Formule :C26H21NO5Couleur et forme :SolidMasse moléculaire :427.45PDPOB
CAS :PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.Formule :C15H20O5Couleur et forme :SolidMasse moléculaire :280.32Anticancer agent 47
CAS :Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.Formule :C19H14N2O4SCouleur et forme :SolidMasse moléculaire :366.39STAT3-IN-11
CAS :STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.Formule :C20H17NO4Degré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :335.35Anticancer agent 55
CAS :Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.Formule :C28H21Br2FN2O2Couleur et forme :SolidMasse moléculaire :596.294Verticillin A
CAS :Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.Formule :C30H28N6O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :696.84HI5
CAS :HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.Formule :C42H43N5O8Couleur et forme :SolidMasse moléculaire :745.82LOM612
CAS :LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.Formule :C13H10N2O2SCouleur et forme :SolidMasse moléculaire :258.3SK-7041
CAS :SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.Formule :C19H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.39GW-3333
CAS :GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.Formule :C22H36N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.55CRA-026440
CAS :CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7Formule :C23H24N4O4Degré de pureté :96.42%Couleur et forme :SolidMasse moléculaire :420.46p-DDAP
CAS :p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.Formule :C18H31NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.44HDAC6-IN-4
CAS :HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.Formule :C30H38N2O5Couleur et forme :SolidMasse moléculaire :506.63PI3K-IN-33
CAS :PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.Formule :C23H21BrN6O2Couleur et forme :SolidMasse moléculaire :493.36BMH-7
CAS :BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Formule :C20H21N5ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :347.41JS-K
CAS :JS-K is a Nitric oxide donor. It has antiproliferative activity.Formule :C13H16N6O8Couleur et forme :SolidMasse moléculaire :384.3VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.Formule :C26H21ClF3N5O3S2Couleur et forme :SolidMasse moléculaire :608.05NSC10010 hydrochloride
CAS :NSC10010 inhibits gammaherpesvirus B-lymphomas by activating NF-κB and c-Myc pathways.Formule :C31H42Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.60PI3Kδ-IN-11
CAS :PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.Formule :C27H21N5OCouleur et forme :SolidMasse moléculaire :431.49AFG206
CAS :AFG206 is the novel first-generation type II" FLT3 inhibitor."Formule :C20H19N3O2Couleur et forme :SolidMasse moléculaire :333.38LWG-301
LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.Formule :C28H38N8O3SCouleur et forme :SolidMasse moléculaire :566.72IDT
CAS :IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formule :C8H5NS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.26ARN5187 trihydrochloride
CAS :ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.Formule :C24H35Cl3FN3OCouleur et forme :SolidMasse moléculaire :506.912AZD 1152 (hydrochloride)
CAS :AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.Formule :C26H33Cl2FN7O6PCouleur et forme :SolidMasse moléculaire :660.47αβ-Tubulin-IN-1
CAS :αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.Formule :C25H19N3O3Couleur et forme :SolidMasse moléculaire :409.44ZMF-10
CAS :ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.Formule :C19H17F6N7OCouleur et forme :SolidMasse moléculaire :473.38MMP-9-IN-3
CAS :MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.Formule :C29H25N3O4Couleur et forme :SolidMasse moléculaire :479.53SCAL-266
CAS :SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.Formule :C27H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.54PDGFR-IN-1
CAS :PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formule :C25H30N8ODegré de pureté :99.13% - 99.49%Couleur et forme :SolidMasse moléculaire :458.56Ref: TM-T62872
1mg170,00€5mg432,00€1mL*10mM (DMSO)434,00€10mg655,00€25mg1.153,00€50mg1.665,00€100mg2.250,00€JMX0293
JMX0293, a salicylamide derivative, inhibits STAT3, inducing MDA-MB-231 cell apoptosis with IC50=3.38μM, while sparing MCF-10A (IC50>60μM).Formule :C25H30Cl2N4O7Couleur et forme :SolidMasse moléculaire :569.43DRAK2-IN-1
CAS :Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.41Rohinitib
CAS :Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.Formule :C29H31NO8Couleur et forme :SolidMasse moléculaire :521.56SCAL-255
CAS :SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.Formule :C27H28F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.54LSD1-IN-14
CAS :LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.Formule :C21H24FN5Couleur et forme :SolidMasse moléculaire :365.45ANO1-IN-3
CAS :ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].Formule :C20H17NO3Couleur et forme :SolidMasse moléculaire :319.35CAY10503
CAS :CAY10503: proapoptotic, anti-growth agent; arrests cell cycle at G0-G1; IC50 = 7-23 μM; induces HL60 differentiation in 72 hours.Formule :C18H14O3Couleur et forme :SolidMasse moléculaire :278.3(5Z,2E)-CU-3
CAS :(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mMFormule :C16H12N2O4S3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :392.47Ref: TM-T10177
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg160,00€25mg340,00€50mg582,00€100mg898,00€500mg1.791,00€Antitumor agent-56
CAS :Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.Formule :C28H28N2O10SCouleur et forme :SolidMasse moléculaire :584.59RIPK1-IN-11
CAS :RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Formule :C23H24N4O4SCouleur et forme :SolidMasse moléculaire :452.53CDK9-IN-18
CAS :CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.Formule :C27H20N8OCouleur et forme :SolidMasse moléculaire :472.5FAK-IN-5
CAS :FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.Formule :C29H29ClF3N3O4Couleur et forme :SolidMasse moléculaire :576.01GDP366
CAS :GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.Formule :C20H17N5OSDegré de pureté :98.78% - 99.84%Couleur et forme :SolidMasse moléculaire :375.45Ivaltinostat
CAS :CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.Formule :C24H33N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.54BIBU-1361 dihydrochloride
CAS :BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.Formule :C22H29Cl3FN7Couleur et forme :SolidMasse moléculaire :516.87p53 Activator 3
CAS :Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formule :C30H37F3N4O4SCouleur et forme :SolidMasse moléculaire :606.7c-Fms-IN-12
CAS :c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.Formule :C30H32N6O6Couleur et forme :SolidMasse moléculaire :572.61BRD4 Inhibitor-15
CAS :BRD4 Inhibitor-15 targets BRD4 with 18 nM IC50, induces apoptosis in 22RV1 cells, and lowers c-Myc, aiding prostate cancer research.Formule :C22H21N3O2Couleur et forme :SolidMasse moléculaire :359.42VEGFR-2-IN-22
CAS :VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.Formule :C26H24ClFN4O6Couleur et forme :SolidMasse moléculaire :542.94USP7-IN-4
CAS :USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .Formule :C29H34N6O3Degré de pureté :98.27% - 99.09%Couleur et forme :SolidMasse moléculaire :514.62IHMT-TRK-284
CAS :IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Formule :C25H27N7OSCouleur et forme :SolidMasse moléculaire :473.59BJE6-106
CAS :BJE6-106, Selective PKCδ inhibitor (IC50=0.05 μM), induces caspase-dependent apoptosis, activates JNK/H2AX, for NRAS-mutated melanoma.Formule :C26H23NO2Couleur et forme :SolidMasse moléculaire :381.47AQX-016A
CAS :AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49PDK4-IN-1
CAS :PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).Formule :C22H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.41
