Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(128 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6172 produits trouvés pour "Apoptose"
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Anti-melanoma agent 1
CAS :Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.Formule :C28H28N2O2Couleur et forme :SolidMasse moléculaire :424.53UCD38B HCl
CAS :UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.Formule :C15H17Cl2N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.25Targapremir-210
CAS :Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.Formule :C32H36N10O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :592.69Flonoltinib
CAS :Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.Formule :C25H34FN7ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :467.58BLM-IN-1
CAS :BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.Formule :C28H35FN4OCouleur et forme :SolidMasse moléculaire :462.6NPD4928
CAS :NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Formule :C29H32N2O6Couleur et forme :SolidMasse moléculaire :504.57HX 630
CAS :RXR agonistFormule :C28H27NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.58Mitoguazone
CAS :Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.Formule :C5H12N8Degré de pureté :97.47% - 98%Couleur et forme :SolidMasse moléculaire :184.2TRAF-STOP inhibitor 6877002
CAS :TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.Formule :C17H17NODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :251.32(1S,2S)-Bortezomib
CAS :(1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib.Formule :C19H25BN4O4Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :384.24Ref: TM-T10061
1mg60,00€2mg92,00€5mg160,00€1mL*10mM (DMSO)163,00€10mg269,00€25mg429,00€50mg583,00€100mg783,00€WJ35435
CAS :WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.Formule :C20H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.4BR102375
CAS :BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.Formule :C31H34N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.64MIR96-IN-1
CAS :MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.Formule :C33H48N8O2Couleur et forme :SolidMasse moléculaire :588.79R-8507
CAS :R-8507: TNF-αRI antagonist, blocks ICAM-1, halts receptor complex internalization, EC50: 2.45 μM (TNF-α), 3.79 μM (IL-1β).Formule :C16H8ClF3N4Couleur et forme :SolidMasse moléculaire :348.71Antitumor agent-44
CAS :Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in humanFormule :C24H15N3O3Couleur et forme :SolidMasse moléculaire :393.39PARP1-IN-31
CAS :PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).Formule :C22H15ClFN3O2Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :407.83c-Met-IN-9
CAS :c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.Formule :C25H19F2N5O3Couleur et forme :SolidMasse moléculaire :475.45B-Raf IN 9
CAS :B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).Formule :C23H20N4OSCouleur et forme :SolidMasse moléculaire :400.5PI3Kα-IN-7
CAS :PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.Formule :C17H22N8O2SCouleur et forme :SolidMasse moléculaire :402.47PERK-IN-3
CAS :PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).Formule :C22H16F2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.38MCL-1/BCL-2-IN-3
CAS :MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.Formule :C27H25BrN2O5SCouleur et forme :SolidMasse moléculaire :569.47Metaproterenol
CAS :Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).Formule :C11H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :211.26Ozarelix
CAS :Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.Formule :C72H96ClN17O14Couleur et forme :SolidMasse moléculaire :1459.09NSC 146109 hydrochloride
CAS :NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.Formule :C17H17ClN2SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :316.85GZD856
CAS :GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.Formule :C29H27F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.56IDH1 Inhibitor 9
CAS :IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.Formule :C26H30N4O3Couleur et forme :SolidMasse moléculaire :446.54iMAC2
CAS :iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibitingFormule :C19H20Br2FN3Couleur et forme :SolidMasse moléculaire :469.19Xanthine oxidase-IN-6
Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.Formule :C29H34N2O15Couleur et forme :SolidMasse moléculaire :650.58VEGFR-2/BRAF-IN-1
VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.Formule :C26H20Cl2F3N5O3S2Couleur et forme :SolidMasse moléculaire :642.5Rhosin
CAS :Rhosin is a specific inhibitor of RhoA GTPases (Kd: ~0.4 uM), blocking RhoA-GEF interaction, not affecting Cdc42/Rac1/LARG, and induces apoptosis.Formule :C20H18N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.4Apoptotic agent-1
CAS :Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.Formule :C12H6ClN5O2SCouleur et forme :SolidMasse moléculaire :319.73RET-IN-12
CAS :RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).Formule :C30H30F3N5O4Couleur et forme :SolidMasse moléculaire :581.59LG190178
CAS :LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.
Formule :C28H42O5Couleur et forme :SolidMasse moléculaire :458.63MDM2-IN-1
CAS :MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.Formule :C23H21Cl2FN2O3Couleur et forme :SolidMasse moléculaire :463.33hCAIX-IN-12
CAS :hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.Formule :C18H14N4O3S2Couleur et forme :SolidMasse moléculaire :398.46Tigilanol tiglate
CAS :Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.Formule :C30H42O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :562.65A-802715
CAS :A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases theFormule :C16H26N4O3Degré de pureté :96.29%Couleur et forme :SolidMasse moléculaire :322.4PIK-C98
CAS :PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.Formule :C16H10Cl2N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.23MI-389
CAS :MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.Formule :C35H35FN6O6Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :654.69Ref: TM-T33380
1mg90,00€5mg188,00€1mL*10mM (DMSO)255,00€10mg280,00€25mg439,00€50mg762,00€100mg1.314,00€TJ08
CAS :TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.Formule :C22H16FN3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :405.38Antitumor agent-19
CAS :Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.Formule :C24H21ClF3N5ODegré de pureté :98.95% - 99.38%Couleur et forme :SolidMasse moléculaire :487.9Ref: TM-T10341
1mg109,00€2mg163,00€5mg241,00€1mL*10mM (DMSO)289,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.035,00€APPA
CAS :APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition ofFormule :C14H13NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.262,3-DCPE
CAS :Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).Formule :C11H15Cl2NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :264.15MIR002
CAS :MIR002: an oral POLA1/HDAC11 inhibitor with antitumor effects, enhances p53/p21, causes G1/S arrest, and triggers apoptosis.Formule :C27H29NO5Couleur et forme :SolidMasse moléculaire :447.52Dimethoate
CAS :Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.Formule :C5H12NO3PS2Degré de pureté :99.74% - 99.91%Couleur et forme :White Crystalline SolidMasse moléculaire :229.26CPI-7c
CAS :CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.Formule :C22H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.39ALC67
CAS :ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.Formule :C15H15NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :289.35L 741742 (free base)
CAS :L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).Formule :C23H25ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.91BMH-9
CAS :BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formule :C19H27N3O2Couleur et forme :SolidMasse moléculaire :329.44A 410099.1
CAS :A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formule :C27H41ClN4O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :505.1L6H21
CAS :L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.Formule :C18H18O4Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :298.33Bisindolylmaleimide VIII
CAS :Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.
Formule :C24H22N4O2Degré de pureté :97% - 98.01%Couleur et forme :SolidMasse moléculaire :398.46BP-1-108
CAS :BP-1-108 is a potent and selective STAT5 inhibitor.Formule :C32H38N2O6SCouleur et forme :SolidMasse moléculaire :578.72Apoptosis inducer 6
CAS :Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.Formule :C27H26N4O3SCouleur et forme :SolidMasse moléculaire :486.59Bozepinib
CAS :Bozepinib is an antitumor compound that acts by inducing PKR-mediated apoptosis and synergizing with IFN.Formule :C20H14Cl2N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.33ASK1-IN-3
CAS :ASK1-IN-3, selective ASK1 inhibitor with 33.8 nM IC50; inhibits cell cycle kinases; induces apoptosis in HepG2 cells.Formule :C18H18N8O2Couleur et forme :SolidMasse moléculaire :378.39ATAD2-IN-1
CAS :ATAD2-IN-1 (compound 19f) serves as a potent ATAD2 inhibitor (IC 50: 0.27 μM), capable of inducing apoptosis. Additionally, it suppresses c-Myc activation and impedes the migration of BT-549 cells [1].Formule :C22H26N6O5Couleur et forme :SolidMasse moléculaire :454.48RIP1 kinase inhibitor 5
CAS :RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) inFormule :C13H17F2NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :257.28Tolbutamide Sodium
CAS :potassium channel blockerFormule :C12H18N2NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.34CCT128930
CAS :'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'Formule :C18H20ClN5Degré de pureté :99.07% - 99.18%Couleur et forme :SolidMasse moléculaire :341.84Ref: TM-T6303
2mg39,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg88,00€25mg166,00€50mg259,00€100mg388,00€200mg617,00€MPT0B002
CAS :MPT0B002 is a microtubule inhibitor that acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cellsFormule :C19H19NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.36PD-1/PD-L1-IN 6
CAS :Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.Formule :C25H26N2O3Couleur et forme :SolidMasse moléculaire :402.49E64FC26
CAS :E64FC26 is a PDI family pan-inhibitor with antitumor activity that inhibits PDIA1 and PDIA6 and can be used to study multiple myeloma and pancreatic cancer.Formule :C19H23F3O2Degré de pureté :98.1% - 98.1%Couleur et forme :SolidMasse moléculaire :340.38Pim-1 kinase inhibitor 1
CAS :Pim-1 kinase inhibitor 1, IC50 0.11 μM, combats various cancers by inducing apoptosis.Formule :C19H13N3O3Couleur et forme :SolidMasse moléculaire :331.32Mcl-1 inhibitor 10
CAS :Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.Formule :C21H15F3O4Couleur et forme :SolidMasse moléculaire :388.34MDM2/XIAP-IN-2
CAS :MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).Formule :C29H32N2O4SCouleur et forme :SolidMasse moléculaire :504.64YM-155 hydrochloride
CAS :Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].Formule :C20H19ClN4O3Couleur et forme :SolidMasse moléculaire :398.85(rel)-Oxaliplatin
CAS :(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.Formule :C8H14N2O4PtCouleur et forme :SolidMasse moléculaire :397.29Vin-F03
CAS :Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.Formule :C22H29N3Couleur et forme :SolidMasse moléculaire :335.49IQDMA
CAS :IQDMA is an inhibitor of the transcription factor STAT5.Formule :C19H20N4Couleur et forme :SolidMasse moléculaire :304.39Undecylprodigiosin
CAS :Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.Formule :C25H35N3OCouleur et forme :SolidMasse moléculaire :393.56PD-1/PD-L1-IN-20
CAS :PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction.Formule :C30H26BrClN2O3Couleur et forme :SolidMasse moléculaire :577.9MX107
CAS :MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49HDAC-IN-51
HDAC-IN-51 is an HDAC inhibitor.Formule :C27H24N4O2Degré de pureté :98.85%Couleur et forme :SolidMasse moléculaire :436.51Anticancer agent 55
CAS :Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.Formule :C28H21Br2FN2O2Couleur et forme :SolidMasse moléculaire :596.294PD-1/PD-L1-IN-25
CAS :"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."Formule :C26H24ClN3O5Couleur et forme :SolidMasse moléculaire :493.94EGFR-IN-88
CAS :EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormule :C22H18Cl2N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.37CCT373566
CAS :CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.Formule :C26H29ClF2N6O3Couleur et forme :SolidMasse moléculaire :547Apoptotic agent-3
CAS :"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."Formule :C31H21N5OSCouleur et forme :SolidMasse moléculaire :511.6TrxR inhibitor D9
CAS :TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).Formule :C25H20AuOPSCouleur et forme :SolidMasse moléculaire :596.43p53 Activator 2
CAS :p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.Formule :C20H21N5O2Couleur et forme :SolidMasse moléculaire :363.41(S)-PERK-IN-5
CAS :(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).Formule :C25H26F2N4O3Couleur et forme :SolidMasse moléculaire :468.5Se-Methylselenocysteine hydrochloride
CAS :Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.Formule :C4H10ClNO2SeDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :218.54MMP2-IN-1
CAS :MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.Formule :C15H13NO5SCouleur et forme :SolidMasse moléculaire :319.33Quinidine polygalacturonate
CAS :Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.Formule :C26H34N2O9Couleur et forme :SolidMasse moléculaire :518.22643EGFR-IN-60
CAS :EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.Formule :C28H28Cl2N6OCouleur et forme :SolidMasse moléculaire :535.47TRK-IN-23
CAS :TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,Formule :C20H17FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.37NSC114792
CAS :NSC114792 is a selective JAK3 inhibitor.Formule :C26H32N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.62CDK/HDAC-IN-2
CAS :CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.Formule :C25H20Cl2N6O3Couleur et forme :SolidMasse moléculaire :523.37GGTI-2154
CAS :GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity againstFormule :C24H28N4O3Couleur et forme :SolidMasse moléculaire :420.5Bcl-2/Mcl-1-IN-3
CAS :Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.Formule :C27H26ClNO4Couleur et forme :SolidMasse moléculaire :463.95Anticancer agent 56
CAS :Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.Formule :C20H18ClN3O3Couleur et forme :SolidMasse moléculaire :383.83(S)-Erypoegin K
CAS :(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.35(Rac)-Indoximod
CAS :(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.Formule :C12H14N2O2Couleur et forme :SolidMasse moléculaire :218.25CZS-241
CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.Formule :C26H24ClF2N9OCouleur et forme :SolidMasse moléculaire :551.98RET-IN-15
CAS :RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.Formule :C27H28N8O2Couleur et forme :SolidMasse moléculaire :496.56Anticancer agent 71
CAS :Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.Formule :C18H13ClF3N5OCouleur et forme :SolidMasse moléculaire :407.78Arylquin 1
CAS :Arylquin 1: a Par-4 secretagogue targeting vimentin; causes non-apoptotic cancer cell death via LMP.Formule :C17H16FN3Couleur et forme :SolidMasse moléculaire :281.33Mammea A/BA
CAS :Mammea A/BA combats T. cruzi by causing mitochondrial damage, ROS, DNA fragmentation, and vacuolization, leading to cell death. Useful for Chagas research.Formule :C25H26O5Couleur et forme :SolidMasse moléculaire :406.47Aurora A inhibitor 2
CAS :Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).Formule :C24H26N6O3Couleur et forme :SolidMasse moléculaire :446.5
